GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1151 - 1175** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Catenin beta-1 Dipeptidyl peptidase 4 Free fatty acid receptor 1 Free fatty acid receptor 4 Gastrin-releasing peptide Glucose-dependent insulinotropic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Homeobox protein CDX-2 Leptin Neuroendocrine convertase 1 Paired box protein Pax-6 Pro-glucagon Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Transcription factor 7-like 2	A8MTJ3 O14842 P01275 P07492 P16520 P26367 P27487 P29120 P35222 P41159 P61009 P62873 P67812 Q15005 Q5NUL3 Q8TDV5 Q99626 Q9BY50 Q9NQB0 Q9P2W3 Q9Y6A9	ADCP2 AN2 CD26 CDX2 CDX3 CTNNB CTNNB1 DPP4 FFAR1 FFAR4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GPR120 GPR129 GPR40 GRP KIAA0102 LEP NEC1 O3FAR1 OB OBS PAX6 PCSK1 PGR4 SEC11A SEC11C SEC11L1 SEC11L3 SPC12 SPC18 SPC21 SPC22 SPC25 SPCS1 SPCS2 SPCS3 SPCS4A SPCS4C TCF4 TCF7L2	Homo sapiens (human)	G58161NS
Activated NTRK3 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 NT-3 growth factor receptor Neurotrophin-3	P19174 P20783 Q16288	NTF3 NTRK3 PLC1 PLCG1 TRKC	Homo sapiens (human)
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta CD44 antigen Calcineurin B homologous protein 1 Hyaluronan mediated motility receptor Hyaluronidase-1 Hyaluronidase-2 Hyaluronidase-3 Lymphatic vessel endothelial hyaluronic acid receptor 1 Sodium/hydrogen exchanger 1 Stabilin-2	O43820 O75330 P06865 P07686 P08236 P16070 P19634 Q12794 Q12891 Q8WWQ8 Q99653 Q9Y5Y7	APNH1 CD44 CHP CHP1 CRSBP1 FEEL2 FELL FEX2 GUSB HAR HARE HEXA HEXB HMMR HYAL1 HYAL2 HYAL3 IHABP LHR LUCA1 LUCA2 LUCA3 LYVE1 MDU2 MDU3 MIC4 NHE1 RHAMM SLC9A1 STAB2 XLKD1	Homo sapiens (human)	G35674CY
Interleukin-18 signaling	Interleukin-13 Interleukin-18 receptor 1 Interleukin-18 receptor accessory protein Interleukin-18-binding protein Interleukin-18 Interleukin-37 Interleukin-4 Polyunsaturated fatty acid 5-lipoxygenase	O95256 O95998 P05112 P09917 P35225 Q13478 Q14116 Q9NZH6	ALOX5 FIL1Z IGIF IL13 IL18 IL18BP IL18R1 IL18RAP IL1F4 IL1F7 IL1H4 IL1R7 IL1RP1 IL1RRP IL37 IL4 LOG5 NC30	Homo sapiens (human)
STAT6-mediated induction of chemokines	Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 6 Stimulator of interferon genes protein	P42226 Q86WV6 Q9UHD2	ERIS MITA NAK STAT6 STING STING1 TBK1 TMEM173	Homo sapiens (human)
Endosomal/Vacuolar pathway	Beta-2-microglobulin Cathepsin L2 Cathepsin S HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G Leucyl-cystinyl aminopeptidase Procathepsin L Putative HLA class I histocompatibility antigen, alpha chain H	O60911 P01889 P01893 P04439 P07711 P10321 P13747 P17693 P25774 P30511 P61769 Q9UIQ6	B2M CATL2 CTSL CTSL1 CTSL2 CTSS CTSU CTSV HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH LNPEP OTASE	Homo sapiens (human)
Activated NTRK2 signals through CDK5	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 Ras-related C3 botulinum toxin substrate 1 Rho guanine nucleotide exchange factor TIAM1	P23560 P63000 Q00535 Q13009 Q15078 Q16620	BDNF CDK5 CDK5R CDK5R1 CDKN5 NCK5A NTRK2 PSSALRE RAC1 TC25 TIAM1 TRKB	Homo sapiens (human)
FLT3 signaling by CBL mutants	E3 ubiquitin-protein ligase CBL Fms-related tyrosine kinase 3 ligand Polyubiquitin-B Polyubiquitin-C Receptor-type tyrosine-protein kinase FLT3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P0CG47 P0CG48 P22681 P36888 P49771 P62979 P62987	CBL CBL2 CD135 FLK2 FLT3 FLT3LG RNF55 RPS27A STK1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Reversible hydration of carbon dioxide	Carbonic anhydrase 12 Carbonic anhydrase 13 Carbonic anhydrase 14 Carbonic anhydrase 1 Carbonic anhydrase 2 Carbonic anhydrase 3 Carbonic anhydrase 4 Carbonic anhydrase 5A, mitochondrial Carbonic anhydrase 5B, mitochondrial Carbonic anhydrase 6 Carbonic anhydrase 7 Carbonic anhydrase 9	O43570 P00915 P00918 P07451 P22748 P23280 P35218 P43166 Q16790 Q8N1Q1 Q9ULX7 Q9Y2D0	CA1 CA12 CA13 CA14 CA2 CA3 CA4 CA5 CA5A CA5B CA6 CA7 CA9 G250 MN	Homo sapiens (human)
Regulation of actin dynamics for phagocytic cup formation	Abl interactor 1 Abl interactor 2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Actin-binding protein WASF3 Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 1B Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 Cell division control protein 42 homolog Cofilin-1 Cytoplasmic FMR1-interacting protein 1 Cytoplasmic FMR1-interacting protein 2 Dedicator of cytokinesis protein 1 Engulfment and cell motility protein 1 Engulfment and cell motility protein 2 Focal adhesion kinase 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta High affinity immunoglobulin gamma Fc receptor I IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) LIM domain kinase 1 Low affinity immunoglobulin gamma Fc region receptor II-a Low affinity immunoglobulin gamma Fc region receptor III-A Merlin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin-2 Myosin-9 NCK-interacting protein with SH3 domain Nck-associated protein 1-like Nck-associated protein 1 Protein BRICK1 Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 SH2/SH3 adapter protein NCK1 Serine/threonine-protein kinase PAK 1 T-cell surface glycoprotein CD3 gamma chain Tyrosine-protein kinase ABL1 Tyrosine-protein kinase BTK Tyrosine-protein kinase SYK UGa8H (Fragment) Unconventional myosin-IXb Unconventional myosin-Ic Unconventional myosin-Va Unconventional myosin-X V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 A6NGB9 O00159 O00401 O15143 O15144 O15145 O15511 O43516 P00519 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P07900 P08238 P08637 P09693 P0CF74 P0CG04 P0DOY2 P0DOY3 P12314 P12318 P15498 P16333 P23083 P23528 P27361 P28482 P35240 P35579 P42768 P43405 P46108 P52735 P53667 P55160 P59998 P60709 P60953 P61158 P61160 P63000 P63261 P80748 Q05397 Q06187 Q13153 Q13459 Q14185 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q7L576 Q8IZP0 Q8TF74 Q8WUW1 Q92556 Q92558 Q92747 Q96F07 Q96JJ3 Q9HD67 Q9NYB9 Q9NZQ3 Q9UKW4 Q9UKX2 Q9UPY6 Q9UQB8 Q9Y2A7 Q9Y4I1 Q9Y6W5	ABI1 ABI2 ABL ABL1 ACTB ACTG ACTG1 ACTR2 ACTR3 AF3P21 AGMX1 ARC16 ARC20 ARC21 ARC34 ARC41 ARGBPIA ARP2 ARP3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ATK BAIAP2 BPK BRK1 BTK C3orf10 CD16A CD32 CD3G CDC42 CED12A CFL CFL1 CR16 CRK CYFIP1 CYFIP2 DOCK1 ELMO1 ELMO2 ERK1 ERK2 FAK FAK1 FCG1 FCG2 FCG3 FCGR1 FCGR1A FCGR2A FCGR2A1 FCGR3 FCGR3A HEM1 HEM2 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB IGFR1 IGFR2 IGFR3 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IMD2 JTK7 KIAA0068 KIAA0269 KIAA0281 KIAA0587 KIAA0799 KIAA0900 KIAA1168 KIAA1834 LIMK LIMK1 MAPK1 MAPK3 MYH12 MYH2 MYH9 MYHSA2 MYO10 MYO1C MYO5A MYO9B MYR5 NAP1 NCK NCK1 NCKAP1 NCKAP1L NCKIPSD NF2 PAK1 PIR121 PRKM1 PRKM2 PRKM3 PTK2 RAC1 SCAR1 SCAR3 SCH SOP2L SPIN90 SSH3BP1 SYK T3G TC25 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3 WAS WASF1 WASF2 WASF3 WASL WASPIP WAVE1 WAVE2 WAVE3 WICH WIP WIPF1 WIPF2 WIPF3 WIRE	Homo sapiens (human)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon regulatory factor 7 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q06124 Q13114 Q14164 Q14653 Q86XR7 Q8IUC6 Q92844 Q92985 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI IRF3 IRF7 ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB PTP2C PTPN11 RPS27A SHPTP2 TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	P15121 Q00796	AKR1B1 ALDR1 ALR2 SORD	Homo sapiens (human)	G58161NS
Defective CSF2RB causes SMDP5	Cytokine receptor common subunit beta Granulocyte-macrophage colony-stimulating factor receptor subunit alpha Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Surfactant protein C Surfactant-associated protein 3	P07988 P0C7M3 P11686 P15509 P32927 P35247 Q8IWL1 Q8IWL2	COLEC4 COLEC5 COLEC7 CSF2R CSF2RA CSF2RB CSF2RY IL3RB IL5RB PSAP PSPD SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH	Homo sapiens (human)
Atorvastatin ADME	ATP-binding cassette sub-family C member 2 ATP-dependent translocase ABCB1 Cytochrome P450 3A4 Serum paraoxonase/arylesterase 1 Serum paraoxonase/lactonase 3 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 UDP-glucuronosyltransferase 1A3	P08183 P08684 P27169 P35503 Q15166 Q92887 Q9NPD5 Q9Y6L6	ABCB1 ABCC2 CMOAT CMOAT1 CMRP CYP3A3 CYP3A4 GNT1 LST1 LST2 MDR1 MRP2 OATP1B1 OATP1B3 OATP2 OATP8 OATPC PGY1 PON PON1 PON3 SLC21A6 SLC21A8 SLCO1B1 SLCO1B3 UGT1 UGT1A3	Homo sapiens (human)
Defective BTD causes biotidinase deficiency	Biotinidase	P43251	BTD	Homo sapiens (human)
Methylation	Adenosylhomocysteinase Arsenite methyltransferase Catechol O-methyltransferase Cytochrome P450 1A2 Glutathione S-transferase omega-1 Methionine adenosyltransferase 2 subunit beta Methionine synthase reductase Methionine synthase Methyltransferase N6AMT1 Multifunctional methyltransferase subunit TRM112-like protein Nicotinamide N-methyltransferase S-adenosylmethionine synthase isoform type-1 S-adenosylmethionine synthase isoform type-2 Thiopurine S-methyltransferase	P05177 P21964 P23526 P31153 P40261 P51580 P78417 Q00266 Q99707 Q9HBK9 Q9NZL9 Q9UBK8 Q9UI30 Q9Y5N5	AHCY AMS1 AMS2 AS3MT C21orf127 COMT CYP1A2 CYT19 GSTO1 GSTTLP28 HEMK2 KMT9 MAT1A MAT2A MAT2B MATA1 MATA2 MTR MTRR N6AMT1 NNMT PRED28 SAHH TGR TPMT TRMT112	Homo sapiens (human)
Defective F8 binding to the cell membrane	Coagulation factor VIII	P00451	F8 F8C	Homo sapiens (human)
Glycosphingolipid biosynthesis	2-hydroxyacylsphingosine 1-beta-galactosyltransferase Alpha-2,8-sialyltransferase 8E Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Beta-1,3-galactosyltransferase 4 Beta-1,4 N-acetylgalactosaminyltransferase 1 Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase 6 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 Ceramide glucosyltransferase Ceramide kinase Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Galactosylceramide sulfotransferase Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase UDP-GalNAc	O15466 O43286 O75752 O96024 P19526 Q00973 Q10981 Q11203 Q16739 Q16842 Q16880 Q8TCT0 Q969X2 Q99999 Q9BVH7 Q9BYG0 Q9NPC4 Q9UBX8 Q9UNP4	A14GALT A4GALT A4GALT1 B3GALNT1 B3GALT3 B3GALT4 B3GNT5 B4GALNT1 B4GALT5 B4GALT6 CERK CGT CST FUT1 FUT2 GAL3ST1 GALGT GALT4 H HSC KIAA1646 SEC2 SIAT2 SIAT4B SIAT6 SIAT7E SIAT7F SIAT8E SIAT9 ST3GAL2 ST3GAL3 ST3GAL5 ST6GALNAC5 ST6GALNAC6 ST8SIA5 UGCG UGT4 UGT8	Homo sapiens (human)
Regulation of Apoptosis	Dynamin-like GTPase OPA1, mitochondrial Metalloendopeptidase OMA1, mitochondrial	O60313 Q96E52	KIAA0567 MPRP1 OMA1 OPA1	Homo sapiens (human)
Type I hemidesmosome assembly	CD151 antigen Collagen alpha-1(XVII) chain Dystonin Integrin alpha-6 Integrin beta-4 Laminin subunit alpha-3 Laminin subunit beta-3 Laminin subunit gamma-2 Plectin	P16144 P23229 P48509 Q03001 Q13751 Q13753 Q15149 Q16787 Q9UMD9	BP180 BP230 BP240 BPAG1 BPAG2 CD151 COL17A1 DMH DST DT ITGA6 ITGB4 KIAA0728 LAMA3 LAMB2T LAMB3 LAMC2 LAMNA LAMNB1 LAMNB2 PLEC PLEC1 TSPAN24	Homo sapiens (human)
Vpu mediated degradation of CD4	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 F-box/WD repeat-containing protein 1A Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein Vpu S-phase kinase-associated protein 1 T-cell surface glycoprotein CD4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 P01730 P05919 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62979 P62987 P63208 Q13200 Q15008 Q16186 Q99436 Q99460 Q9UNM6 Q9Y297	ADRM1 BTRC BTRCP C7orf76 CD4 DSS1 EMC19 FBW1A FBXW1A GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z vpu	Homo sapiens (human)
Maturation of TCA enzymes and regulation of TCA cycle	Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Citrate synthase, mitochondrial Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial Frataxin, mitochondrial Iron-sulfur cluster assembly 1 homolog, mitochondrial Iron-sulfur cluster assembly 2 homolog, mitochondrial Isocitrate dehydrogenase [NADP], mitochondrial LYR motif-containing protein 4 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase assembly factor 1, mitochondrial Succinate dehydrogenase assembly factor 2, mitochondrial Succinate dehydrogenase assembly factor 3, mitochondrial Succinate dehydrogenase assembly factor 4, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial	A6NFY7 A8MUP2 O14521 O75390 P21912 P24752 P31040 P48735 Q16595 Q5VUM1 Q86U28 Q99643 Q99798 Q9BUE6 Q9HD34 Q9NRP4 Q9NTG7 Q9NX18	ACAT ACAT1 ACN9 ACO2 C11orf79 C6orf149 C6orf57 CS CSKMT CYB560 FRDA FXN HBLD1 HBLD2 IDH2 ISCA1 ISCA2 ISD11 LYRM4 LYRM8 MAT METTL12 PGL2 SDH SDH1 SDH2 SDH3 SDH4 SDH5 SDHA SDHAF1 SDHAF2 SDHAF3 SDHAF4 SDHB SDHC SDHD SDHF SIR2L3 SIRT3 X25	Homo sapiens (human)
Negative regulators of RIG-I/MDA5 signaling	Antiviral innate immune response receptor RIG-I Autophagy protein 5 E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RNF125 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase RNF216 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon regulatory factor 3 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein NLR family member X1 OTU domain-containing protein 5 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Poly(rC)-binding protein 2 Polyubiquitin-B Polyubiquitin-C Protein NLRC5 Serine/threonine-protein kinase TBK1 TNF receptor-associated factor 3 Tax1-binding protein 1 Tumor necrosis factor alpha-induced protein 3 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 K Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ATG12 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 O94817 O95786 P05161 P0CG47 P0CG48 P21580 P41226 P51668 P61077 P61086 P62837 P62979 P62987 Q13114 Q13526 Q14164 Q14258 Q14653 Q15366 Q7Z434 Q86UT6 Q86VP1 Q86WI3 Q8IUD6 Q96EQ8 Q96G74 Q96J02 Q9BYX4 Q9C037 Q9H1Y0 Q9NQC7 Q9NWF9 Q9UHD2 Q9UII4	APG12 APG12L APG5L ASP ATG12 ATG5 CAP-1 CEB1 CEBP1 CRAF1 CYLD CYLD1 DDX58 EFP G1P2 HERC5 HIP2 IFIH1 IKBKE IKKE IKKI IPS1 IRF3 ISG15 ITCH KIAA0151 KIAA0849 KIAA1271 LIG MAVS MDA5 NAK NLRC5 NLRX1 NOD27 NOD4 NOD5 NOD9 OTUD5 OTUD7C PCBP2 PIN1 PUBC1 RH116 RIGI RNF125 RNF135 RNF147 RNF216 RNF87 RPS27A SFT T6BP TAX1BP1 TBK1 TNFAIP3 TRAF3 TRAFAMN TRIAD3 TRIM25 TRIM4 UBA52 UBA7 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCE7IP1 UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBCH8 UBE1L UBE2 UBE2D1 UBE2D2 UBE2D3 UBE2K UBE2L6 UCRP VISA ZIN ZNF147	Homo sapiens (human)
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Artemin Docking protein 1 Docking protein 2 Docking protein 4 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GDNF family receptor alpha-3 GDNF family receptor alpha-4 GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Glial cell line-derived neurotrophic factor Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase 7 Neurturin PDZ and LIM domain protein 7 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Protein kinase C alpha type Proto-oncogene tyrosine-protein kinase receptor Ret Rap1 GTPase-activating protein 1 SH3 and multiple ankyrin repeat domains protein 3 SHC-transforming protein 1 SHC-transforming protein 3 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00329 O00451 O00459 O60496 O60542 O60609 P07949 P17252 P17612 P19174 P22612 P22694 P27986 P29353 P39905 P42336 P42338 P47736 P56159 Q06124 Q07889 Q13164 Q13322 Q13480 Q14451 Q5T4W7 Q6PKX4 Q8TEW6 Q8WU20 Q92529 Q92569 Q99704 Q99748 Q9BYB0 Q9GZZ7 Q9NR12 Q9P104 Q9UQC2 Q9Y4H2	ARTN BMK1 C20orf180 CDHF12 CDHR16 DOK1 DOK2 DOK4 DOK5 DOK5L DOK6 ENIGMA ERK5 EVN FRS2 GAB1 GAB2 GDNF GDNFRA GDNFRB GFRA1 GFRA2 GFRA3 GFRA4 GRB1 GRB10 GRB7 GRBIR IRS2 KIAA0207 KIAA0474 KIAA0571 KIAA1650 MAPK7 NRTN NSHC PDLIM7 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PKACA PKCA PLC1 PLCG1 PRKACA PRKACB PRKACG PRKCA PRKM7 PROSAP2 PSAP2 PSPN PTC PTP2C PTPN11 RAP1GA1 RAP1GAP RET RETL1 RETL2 SHANK3 SHC SHC1 SHC3 SHCA SHCC SHPTP2 SOS1 TRNR1 TRNR2	Homo sapiens (human)
PTK6 Regulates Proteins Involved in RNA Processing	KH domain-containing, RNA-binding, signal transduction-associated protein 1 KH domain-containing, RNA-binding, signal transduction-associated protein 2 KH domain-containing, RNA-binding, signal transduction-associated protein 3 Protein-tyrosine kinase 6 Splicing factor, proline- and glutamine-rich	O75525 P23246 Q07666 Q13882 Q5VWX1	BRK KHDRBS1 KHDRBS2 KHDRBS3 PSF PTK6 SALP SAM68 SFPQ SLM1 SLM2	Homo sapiens (human)

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