GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1176 - 1200** of **2090** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	GTPase HRas GTPase NRas Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O00459 O60674 P01111 P01112 P06239 P06241 P07947 P07948 P10721 P27986 P40763 P42224 P42229 P42336 P51692 Q07889 Q92569	APRF FYN GRB1 HRAS HRAS1 JAK2 JTK8 KIT LCK LYN NRAS PIK3CA PIK3R1 PIK3R2 PIK3R3 SCFR SOS1 STAT1 STAT3 STAT5 STAT5A STAT5B YES YES1
Interleukin-23 signaling	Interleukin-12 receptor subunit beta-1 Interleukin-12 subunit beta Interleukin-23 receptor Interleukin-23 subunit alpha Non-receptor tyrosine-protein kinase TYK2 Protein disulfide-isomerase Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK2	O60674 P07237 P29460 P29597 P40763 P42701 Q14765 Q5VWK5 Q9NPF7	APRF ERBA2L IL12B IL12R IL12RB IL12RB1 IL23A IL23R JAK2 NKSF2 P4HB PDI PDIA1 PO4DB SGRF STAT3 STAT4 TYK2
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	Developmental pluripotency-associated protein 4 Ephrin type-A receptor 1 Fibroblast growth factor 2 Forkhead box protein D3 Homeobox protein NANOG POU domain, class 5, transcription factor 1 Protein Cripto Sal-like protein 1 Sal-like protein 4 Signal transducer and activator of transcription 3 Transcription factor SOX-2 Zinc finger protein ZIC 3	O60481 P09038 P13385 P21709 P40763 P48431 Q01860 Q7L190 Q9H9S0 Q9NSC2 Q9UJQ4 Q9UJU5	APRF CRIPTO CRIPTO-1 DPPA4 EPH EPHA1 EPHT EPHT1 FGF2 FGFB FOXD3 HFH2 NANOG OCT3 OCT4 OTF3 POU5F1 SAL1 SALL1 SALL4 SOX2 STAT3 TDGF1 ZIC3 ZNF203 ZNF794 ZNF797
Signaling by Leptin	Insulin receptor substrate 1 Insulin receptor substrate 2 Leptin Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P35568 P40763 P41159 P42229 P51692 Q06124 Q9Y4H2	APRF CIS3 IRS1 IRS2 JAK2 LEP OB OBS PTP2C PTPN11 SHPTP2 SOCS3 SSI3 STAT3 STAT5 STAT5A STAT5B
Signaling by SCF-KIT	Chymase GRB2-associated-binding protein 2 GRB2-related adapter protein 2 GRB2-related adapter protein GTPase HRas GTPase NRas Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 7 Mast/stem cell growth factor receptor Kit Matrix metalloproteinase-9 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Protein kinase C alpha type Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Receptor-type tyrosine-protein phosphatase U Serine/threonine-protein kinase Chk1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Tyrosine-protein kinase Fer Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Tec Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11	O00459 O14757 O60674 O75791 P01111 P01112 P06239 P06241 P07332 P07947 P07948 P10721 P14780 P15498 P16591 P17252 P23946 P27986 P40763 P42224 P42229 P42336 P42680 P51692 P63000 Q06124 Q07889 Q13322 Q13588 Q14451 Q92569 Q92729 Q9UQC2	APRF CHEK1 CHK1 CLG4B CMA1 CYH CYM FER FES FMI FPS FYN GAB2 GADS GRAP GRAP2 GRB1 GRB10 GRB2L GRB7 GRBIR GRID HRAS HRAS1 JAK2 JTK8 KIAA0207 KIAA0571 KIT LCK LYN MMP9 NRAS PCP2 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKCA PRKACA PRKCA PSCTK4 PTP2C PTPN11 PTPRO PTPRU RAC1 SCFR SHPTP2 SOS1 STAT1 STAT3 STAT5 STAT5A STAT5B TC25 TEC TYK3 VAV VAV1 YES YES1
Interleukin-6 signaling	E3 ubiquitin-protein ligase CBL Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P05231 P08887 P22681 P23458 P29597 P40189 P40763 P42224 Q06124	APRF CBL CBL2 CIS3 IFNB2 IL6 IL6R IL6ST JAK1 JAK1A JAK1B JAK2 PTP2C PTPN11 RNF55 SHPTP2 SOCS3 SSI3 STAT1 STAT3 TYK2
Interleukin-35 Signalling	Calnexin Interleukin-12 receptor subunit beta-2 Interleukin-12 subunit alpha Interleukin-27 receptor subunit alpha Interleukin-27 subunit beta Interleukin-6 receptor subunit beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 P23458 P27824 P29459 P29597 P40189 P40763 P42224 Q14213 Q14765 Q6UWB1 Q99665	APRF CANX CRL1 EBI3 IL12A IL12RB2 IL27B IL27RA IL6ST JAK1 JAK1A JAK1B JAK2 NKSF1 STAT1 STAT3 STAT4 TCCR TYK2 WSX1
Interleukin-27 signaling	Calnexin Cytokine receptor-like factor 1 Interleukin-27 receptor subunit alpha Interleukin-27 subunit alpha Interleukin-27 subunit beta Interleukin-6 receptor subunit beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 O75462 P23458 P27824 P29597 P40189 P40763 P42224 Q14213 Q6UWB1 Q8NEV9	APRF CANX CRL1 CRLF1 EBI3 IL27 IL27A IL27B IL27RA IL30 IL6ST JAK1 JAK1A JAK1B JAK2 STAT1 STAT3 TCCR TYK2 WSX1
Inactivation of CSF3 (G-CSF) signaling	Cullin-5 Elongin-B Elongin-C Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Non-receptor tyrosine-protein kinase TYK2 Polyubiquitin-B Polyubiquitin-C RING-box protein 2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14543 O15524 O60674 P07948 P08631 P09919 P0CG47 P0CG48 P23458 P29597 P40763 P42224 P42229 P43405 P51668 P51692 P61077 P62837 P62979 P62987 Q15369 Q15370 Q93034 Q99062 Q9UBF6	APRF C17orf33 CIS3 CSF3 CSF3R CUL5 ELOB ELOC GCSF GCSFR HCK JAK1 JAK1A JAK1B JAK2 JTK8 LYN PUBC1 RBX2 RNF7 ROC2 RPS27A SAG SFT SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TCEB1 TCEB2 TIP3 TYK2 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 VACM1
Interleukin-10 signaling	C-C chemokine receptor type 1 C-C chemokine receptor type 2 C-C chemokine receptor type 5 C-C motif chemokine 19 C-C motif chemokine 20 C-C motif chemokine 22 C-C motif chemokine 2 C-C motif chemokine 3-like 1 C-C motif chemokine 3 C-C motif chemokine 4 C-C motif chemokine 5 C-X-C motif chemokine 10 C-X-C motif chemokine 2 Granulocyte colony-stimulating factor Granulocyte-macrophage colony-stimulating factor Growth-regulated alpha protein Intercellular adhesion molecule 1 Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-10 receptor subunit alpha Interleukin-10 receptor subunit beta Interleukin-10 Interleukin-12 subunit alpha Interleukin-12 subunit beta Interleukin-18 Interleukin-6 Interleukin-8 Leukemia inhibitory factor Low affinity immunoglobulin epsilon Fc receptor Macrophage colony-stimulating factor 1 Metalloproteinase inhibitor 1 Non-receptor tyrosine-protein kinase TYK2 Platelet-activating factor receptor Prostaglandin G/H synthase 2 Signal transducer and activator of transcription 3 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor Tyrosine-protein kinase JAK1 fMet-Leu-Phe receptor	O00626 P01033 P01375 P01583 P01584 P02778 P04141 P05231 P05362 P06734 P09341 P09603 P09919 P10145 P10147 P13236 P13500 P13501 P14778 P15018 P16619 P18510 P19438 P19875 P20333 P21462 P22301 P23458 P25105 P27930 P29459 P29460 P29597 P32246 P33681 P35354 P40763 P41597 P42081 P51681 P78556 Q08334 Q13651 Q14116 Q99731	APRF C17orf33 CCL19 CCL2 CCL20 CCL22 CCL3 CCL3L1 CCL3L3 CCL4 CCL5 CCR1 CCR2 CCR5 CD23A CD28LG CD28LG1 CD28LG2 CD80 CD86 CLEC4J CLGI CMKBR1 CMKBR2 CMKBR5 CMKR1 COX2 CRFB4 CSF1 CSF2 CSF3 CXCL1 CXCL10 CXCL2 CXCL8 D17S136E D17S1718 D21S58 D21S66 ELC FCE2 FCER2 FPR1 G0S19-1 G0S19-2 GCSF GMCSF GRO GRO1 GRO2 GROA GROB HILDA ICAM1 IFNB2 IGEBF IGIF IL10 IL10R IL10RA IL10RB IL12A IL12B IL18 IL1A IL1B IL1F1 IL1F2 IL1F3 IL1F4 IL1R IL1R1 IL1R2 IL1RA IL1RB IL1RN IL1RT1 IL6 IL8 INP10 JAK1 JAK1A JAK1B LAB7 LAG1 LARC LIF MCP1 MDC MGSA MIP1A MIP1B MIP2A MIP3A MIP3B NKSF1 NKSF2 PAFR PTAFR PTGS2 SCYA19 SCYA2 SCYA20 SCYA22 SCYA3 SCYA3L1 SCYA4 SCYA5 SCYAR1 SCYB1 SCYB10 SCYB2 STAT3 TIMP TIMP1 TNF TNFA TNFAR TNFBR TNFR1 TNFR2 TNFRSF1A TNFRSF1B TNFSF2 TYK2
Signaling by CSF1 (M-CSF) in myeloid cells	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 E3 ubiquitin-protein ligase CBL GRB2-associated-binding protein 2 GRB2-associated-binding protein 3 GRB2-related adapter protein 2 GTPase KRas Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1 THO complex subunit 5 homolog Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00329 O15357 O75791 P01116 P06241 P07333 P07947 P07948 P08631 P09603 P0CG47 P0CG48 P12931 P16885 P22681 P27986 P29353 P40763 P42224 P42336 P42338 P62979 P62987 Q06124 Q07889 Q13769 Q6ZMJ4 Q8WWW8 Q92835 Q9UQC2	APRF C16orf77 C22orf19 CBL CBL2 CSF1 CSF1R FMS FYN GAB2 GAB3 GADS GRAP2 GRB1 GRB2L GRID HCK IL34 INPP5D INPPL1 JTK8 KIAA0571 KIAA0983 KRAS KRAS2 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PLCG2 PTP2C PTPN11 RASK2 RNF55 RPS27A SHC SHC1 SHCA SHIP SHIP1 SHIP2 SHPTP2 SOS1 SRC SRC1 STAT1 STAT3 THOC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YES YES1
PTK6 Activates STAT3	Protein-tyrosine kinase 6 Signal transducer and activator of transcription 3 Signal-transducing adaptor protein 2 Suppressor of cytokine signaling 3	O14543 P40763 Q13882 Q9UGK3	APRF BKS BRK CIS3 PTK6 SOCS3 SSI3 STAP2 STAT3
Interleukin-37 signaling	Caspase-1 Interleukin-18 receptor 1 Interleukin-18-binding protein Interleukin-37 Mothers against decapentaplegic homolog 3 Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 3 Single Ig IL-1-related receptor Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type 13 Tyrosine-protein phosphatase non-receptor type 14 Tyrosine-protein phosphatase non-receptor type 18 Tyrosine-protein phosphatase non-receptor type 20 Tyrosine-protein phosphatase non-receptor type 23 Tyrosine-protein phosphatase non-receptor type 2 Tyrosine-protein phosphatase non-receptor type 4 Tyrosine-protein phosphatase non-receptor type 5 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type 7 Tyrosine-protein phosphatase non-receptor type 9	O95998 P17706 P29074 P29350 P29466 P35236 P40763 P43378 P54829 P84022 Q05209 Q06124 Q12923 Q13478 Q15678 Q4JDL3 Q6IA17 Q99952 Q9H3S7 Q9NZH6 Q9UHD2	APRF BDP1 CASP1 FIL1Z HCP IL18BP IL18R1 IL1BC IL1BCE IL1F7 IL1H4 IL1RP1 IL1RRP IL37 KIAA1471 MADH3 NAK PEZ PNP1 PTP1C PTP1E PTP2C PTPD2 PTPL1 PTPN11 PTPN12 PTPN13 PTPN14 PTPN18 PTPN2 PTPN20 PTPN20A PTPN20B PTPN23 PTPN4 PTPN5 PTPN6 PTPN7 PTPN9 PTPT SHPTP2 SIGIRR SMAD3 STAT3 TBK1
Signaling by cytosolic FGFR1 fusion mutants	Breakpoint cluster region protein Centrosomal protein 43 Cleavage and polyadenylation specificity factor subunit 6 FGFR1 oncogene partner 2 GRB2-associated-binding protein 2 Homeobox protein cut-like 1 Leucine-rich repeat flightless-interacting protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Transcription intermediary factor 1-alpha Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	O15164 O95684 P11274 P27986 P39880 P40763 P42224 P42229 P42336 P51692 Q16630 Q32MZ4 Q92614 Q9NVK5 Q9UBW7 Q9UQC2	APRF BCR BCR1 CD245 CEP43 CFIM68 CPSF6 CUTL1 CUX1 D22S11 FGFR1OP FGFR1OP2 FIM FOP GAB2 GCF2 GRB1 KIAA0216 KIAA0571 LRRFIP1 MYO18A MYSPDZ PIK3CA PIK3R1 RAMP RNF82 STAT1 STAT3 STAT5 STAT5A STAT5B TIAF1 TIF1 TIF1A TRIM24 TRIP ZMYM2 ZNF198
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Crk-like protein Cytoplasmic protein NCK2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Proto-oncogene tyrosine-protein kinase Src Rap guanine nucleotide exchange factor 1 Ras GTPase-activating protein 1 SH2/SH3 adapter protein NCK1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription 6 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O00459 O43639 P01111 P01112 P01127 P09619 P12931 P16234 P16333 P19174 P20936 P27986 P40763 P42224 P42226 P42229 P42336 P42338 P46108 P46109 P51692 P56945 Q06124 Q07889 Q13905 Q14451	APRF BCAR1 CAS CASS1 CRK CRKAS CRKL GAP GRB1 GRB4 GRB7 GRF2 HRAS HRAS1 NCK NCK1 NCK2 NRAS PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTP2C PTPN11 RAPGEF1 RASA RASA1 RHEPDGFRA SHPTP2 SIS SOS1 SRC SRC1 STAT1 STAT3 STAT5 STAT5A STAT5B STAT6
Interleukin-7 signaling	Bromodomain and WD repeat-containing protein 1 Cytokine receptor common subunit gamma Cytokine receptor-like factor 2 Cytokine-inducible SH2-containing protein Hepatocyte growth factor Histone H3.1 Histone H3.2 Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin-7 receptor subunit alpha Interleukin-7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 2 Thymic stromal lymphopoietin Transcription activator BRG1 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3 V(D)J recombination-activating protein 1 V(D)J recombination-activating protein 2	O00459 O14508 O15524 P13232 P14210 P15918 P16871 P23458 P27986 P31785 P35568 P40763 P42229 P51532 P51692 P52333 P55895 P68431 Q71DI3 Q92569 Q969D9 Q9HC73 Q9NSE2 Q9NSI6 Q9Y4H2	APRF BAF190A BRG1 BRWD1 C21orf107 CIS2 CISH CRL2 CRLF2 G18 GRB1 H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM HGF HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST2H3A HIST2H3C HIST2H3D HPTA IL2RG IL7 IL7R ILXR IRS1 IRS2 JAK1 JAK1A JAK1B JAK3 PIK3R1 PIK3R2 PIK3R3 RAG1 RAG2 RNF74 SMARCA4 SNF2B SNF2L4 SOCS1 SOCS2 SSI1 SSI2 STAT3 STAT5 STAT5A STAT5B STATI2 TIP3 TSLP TSLPR WDR9
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	Apoptosis regulator Bcl-2 BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 Bcl-2-like protein 11 Bcl-2-like protein 1 Bcl-2-modifying factor Bcl2-associated agonist of cell death Phorbol-12-myristate-13-acetate-induced protein 1 Signal transducer and activator of transcription 3	O43521 P10415 P40763 P55957 Q07817 Q13794 Q92934 Q96LC9 Q9BXH1	APRF BAD BBC3 BBC6 BCL2 BCL2L BCL2L1 BCL2L11 BCL2L8 BCLX BID BIM BMF NOXA PMAIP1 PUMA STAT3
Interleukin-15 signaling	Cytokine receptor common subunit gamma GRB2-associated-binding protein 2 Growth factor receptor-bound protein 2 Interleukin-15 receptor subunit alpha Interleukin-15 Interleukin-2 receptor subunit beta SHC-transforming protein 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Son of sevenless homolog 2 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3	P14784 P23458 P29353 P31785 P40763 P40933 P42229 P51692 P52333 P62993 Q07889 Q07890 Q13261 Q9UQC2	APRF ASH GAB2 GRB2 IL15 IL15RA IL15RB IL2RB IL2RG JAK1 JAK1A JAK1B JAK3 KIAA0571 SHC SHC1 SHCA SOS1 SOS2 STAT3 STAT5 STAT5A STAT5B
Signaling by CSF3 (G-CSF)	GRB2-associated-binding protein 2 GTPase KRas Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Growth factor receptor-bound protein 2 Non-receptor tyrosine-protein kinase TYK2 SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11	O14543 O15524 O60674 P01116 P07948 P08631 P09919 P23458 P29353 P29597 P40763 P42224 P42229 P43405 P51692 P62993 Q06124 Q99062 Q9UQC2	APRF ASH C17orf33 CIS3 CSF3 CSF3R GAB2 GCSF GCSFR GRB2 HCK JAK1 JAK1A JAK1B JAK2 JTK8 KIAA0571 KRAS KRAS2 LYN PTP2C PTPN11 RASK2 SHC SHC1 SHCA SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TIP3 TYK2
Ligand-independent caspase activation via DCC	Caspase-3 Caspase-9 DCC-interacting protein 13-alpha Death-associated protein kinase 1 Death-associated protein kinase 2 Death-associated protein kinase 3 Melanoma-associated antigen D1 Netrin receptor DCC Netrin receptor UNC5A Netrin receptor UNC5B	O43293 P42574 P43146 P53355 P55211 Q6ZN44 Q8IZJ1 Q9UIK4 Q9UKG1 Q9Y5V3	APPL APPL1 CASP3 CASP9 CPP32 DAPK DAPK1 DAPK2 DAPK3 DCC DIP13A IGDCC1 KIAA1428 KIAA1976 MAGED1 MCH6 NRAGE P53RDL1 UNC5A UNC5B UNC5H1 UNC5H2 ZIPK
Cristae formation	ATP synthase F(0) complex subunit B1, mitochondrial ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase F(0) complex subunit C2, mitochondrial ATP synthase F(0) complex subunit C3, mitochondrial ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit delta, mitochondrial ATP synthase subunit e, mitochondrial ATP synthase subunit epsilon, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial ATP synthase subunit s, mitochondrial ATP synthase-coupling factor 6, mitochondrial DnaJ homolog subfamily C member 11 MICOS complex subunit MIC10 MICOS complex subunit MIC13 MICOS complex subunit MIC19 MICOS complex subunit MIC25 MICOS complex subunit MIC26 MICOS complex subunit MIC27 MICOS complex subunit MIC60 Metaxin-1 Metaxin-2 Sorting and assembly machinery component 50 homolog Stress-70 protein, mitochondrial Transmembrane protein 11, mitochondrial	O75431 O75947 O75964 P00846 P03928 P05496 P06576 P17152 P18859 P24539 P25705 P30049 P36542 P38646 P48047 P48201 P56134 P56381 P56385 Q06055 Q13505 Q16891 Q5TGZ0 Q5XKP0 Q6UXV4 Q99766 Q9BRQ6 Q9BUR5 Q9NVH1 Q9NX63 Q9Y512	APOO APOOL ATP5A ATP5A1 ATP5AL2 ATP5B ATP5C ATP5C1 ATP5CL1 ATP5D ATP5E ATP5F1 ATP5F1A ATP5F1B ATP5F1C ATP5F1D ATP5F1E ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5JL ATP5K ATP5L ATP5MC1 ATP5MC2 ATP5MC3 ATP5ME ATP5MF ATP5MG ATP5O ATP5PB ATP5PD ATP5PF ATP5PO ATP5S ATP6 ATP8 ATPASE6 ATPASE8 ATPM ATPMB ATPO ATPSB ATPW C17orf35 C19orf70 C1orf151 CHCHD3 CHCHD6 CHCM1 CXorf33 DMAC2L DNAJC11 FAM121A FAM121B GRP75 HMP HSPA9 HSPA9B IMMT MIC10 MIC13 MIC19 MIC23 MIC25 MIC26 MIC27 MIC60 MICOS10 MICOS13 MINOS1 MINOS2 MINOS3 MT-ATP6 MT-ATP8 MTATP6 MTATP8 MTX MTX1 MTX2 MTXN PM1 QIL1 SAM50 SAMM50 TMEM11 mt-HSP70
Resolution of D-loop Structures through Holliday Junction Intermediates	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein Crossover junction endonuclease EME1 Crossover junction endonuclease MUS81 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA repair-scaffolding protein DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 FIGNL1-interacting regulator of recombination and mitosis Fanconi anemia group J protein Fidgetin-like protein 1 Flap endonuclease GEN homolog 1 Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 Probable crossover junction endonuclease EME2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Serine-protein kinase ATM Structure-specific endonuclease subunit SLX1 Structure-specific endonuclease subunit SLX4	A4GXA9 O15315 O43502 O43542 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14159 Q14191 Q17RS7 Q6PIW4 Q86YC2 Q8IY92 Q92878 Q92993 Q96AY2 Q96B01 Q96E14 Q96NY9 Q99708 Q99728 Q9BQ83 Q9BX63 Q9H9A7 Q9NSG2 Q9UQ84	APOLO1 ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 BTBD12 C16orf75 C1orf112 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EME1 EME2 EXO1 EXOI FACD FANCD1 FANCJ FANCN FIGNL1 FIRRM GEN1 GIYD1 GIYD2 HEX1 HNGS1 HTATIP KAT5 KIAA0083 KIAA0146 KIAA1784 KIAA1987 MMS4 MRE11 MRE11A MUS81 NBN NBS NBS1 P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 SEM1 SHFDG1 SHFM1 SLX1 SLX1A SLX1B SLX4 SPIDR TIP60 TOP3 TOP3A WRN XRCC2 XRCC3
Terminal pathway of complement	Clusterin Complement C5 Complement component C6 Complement component C7 Complement component C8 alpha chain Complement component C8 beta chain Complement component C8 gamma chain Complement component C9	P01031 P02748 P07357 P07358 P07360 P10643 P10909 P13671	APOJ C5 C6 C7 C8A C8B C8G C9 CLI CLU CPAMD4 KUB1
Scavenging by Class H Receptors	Apolipoprotein B-100 SPARC Stabilin-1 Stabilin-2	P04114 P09486 Q8WWQ8 Q9NY15	APOB FEEL1 FEEL2 FELL FEX2 HARE KIAA0246 ON SPARC STAB1 STAB2
Scavenging by Class F Receptors	Apolipoprotein B-100 Calreticulin Heat shock protein 105 kDa Heat shock protein HSP 90-alpha Hypoxia up-regulated protein 1 Major outer membrane protein P.IB Scavenger receptor class F member 1	P04114 P07900 P18195 P27797 Q14162 Q92598 Q9Y4L1	APOB CALR CRTC GRP170 HSP105 HSP110 HSP90A HSP90AA1 HSPC1 HSPCA HSPH1 HSPH4 HYOU1 KIAA0149 KIAA0201 ORP150 SCARF1 SREC porB

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