GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1101 - 1125** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Urea cycle	Arginase-1 Arginase-2, mitochondrial Argininosuccinate lyase Argininosuccinate synthase Carbamoyl-phosphate synthase [ammonia], mitochondrial Mitochondrial ornithine transporter 1 Mitochondrial ornithine transporter 2 N-acetylglutamate synthase, mitochondrial NmrA-like family domain-containing protein 1 Ornithine transcarbamylase, mitochondrial	P00480 P00966 P04424 P05089 P31327 P78540 Q8N159 Q9BXI2 Q9HBL8 Q9Y619	ARG1 ARG2 ASL ASS ASS1 CPS1 HSCARG NAGS NMRAL1 ORC1 ORC2 ORNT1 ORNT2 OTC SLC25A15 SLC25A2	Homo sapiens (human)
Acyl chain remodelling of PS	Cytosolic phospholipase A2 beta Cytosolic phospholipase A2 delta Cytosolic phospholipase A2 epsilon Cytosolic phospholipase A2 zeta Cytosolic phospholipase A2 Group 10 secretory phospholipase A2 Group IID secretory phospholipase A2 Group IIE secretory phospholipase A2 Group IIF secretory phospholipase A2 Group XIIA secretory phospholipase A2 Lysophospholipid acyltransferase 1 Lysophospholipid acyltransferase 5 Lysophospholipid acyltransferase LPCAT4 Oxysterol-binding protein-related protein 10 Oxysterol-binding protein-related protein 5 Oxysterol-binding protein-related protein 8 Phospholipase A and acyltransferase 3 Phospholipase A1 member A Phospholipase A2 group V Phospholipase A2, membrane associated Phospholipase A2 Secretory phospholipase A2 receptor	O15496 P04054 P0C869 P14555 P39877 P47712 P53816 Q13018 Q3MJ16 Q53H76 Q643R3 Q68DD2 Q6P1A2 Q6ZNC8 Q86XP0 Q9BXB5 Q9BZF1 Q9BZM1 Q9BZM2 Q9H0X9 Q9NZK7 Q9UNK4	AGPAT7 AYTL3 CLEC13C CPLA2 HRASLS3 HREV107 KIAA1451 KIAA1534 LPCAT3 LPCAT4 LPEAT2 MBOAT1 MBOAT5 NMD OACT1 OACT5 OBPH1 ORP10 ORP5 ORP8 OSBP10 OSBP9 OSBPL10 OSBPL5 OSBPL8 PLA1A PLA2 PLA2A PLA2B PLA2G10 PLA2G12 PLA2G12A PLA2G16 PLA2G1B PLA2G2A PLA2G2D PLA2G2E PLA2G2F PLA2G4 PLA2G4A PLA2G4B PLA2G4D PLA2G4E PLA2G4F PLA2G5 PLA2L PLA2R1 PLAAT3 PPLA2 PSPLA1 RASF-A SPLASH	Homo sapiens (human)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 20 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 SKA complex subunit 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 2 ZW10 interactor	O00139 O14576 O14777 O14980 O15392 O43237 O43264 O43683 O43684 O60566 O75122 O95229 P30153 P30154 P30622 P36873 P42677 P43034 P46060 P49450 P49454 P49792 P50748 P53350 P55735 P57740 P62714 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14738 Q15172 Q15173 Q15691 Q16537 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q8N0S6 Q8N2Z9 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NI77 Q8WUM0 Q8WVK7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96EA4 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NXR1 Q9P258 Q9Y266 Q9Y6D9 Q9Y6G9	AHCTF1 AIK2 AIM1 AIRK2 API4 APITD1 ARK2 AURKB B9D2 BIRC5 BUB1 BUB1B BUB1L BUB3 BUBR1 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 CASC5 CCDC99 CDC20 CDCA1 CDCA8 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CYLN1 D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ELYS EOPA ERCC6L FAAP16 FAM33A FSHPRH1 HDLC1 HEC HEC1 IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0097 KIAA0166 KIAA0197 KIAA0325 KIAA0622 KIAA0627 KIAA1361 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MCM21R MDCR MDS MHF1 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MPS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PESCRG3 PICH PLK PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RANBP2 RANGAP1 RCC2 ROD RPS27 RSN SD SEC13 SEC13A SEC13L1 SEC13R SGO1 SGO2 SGOL1 SGOL2 SKA1 SKA2 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STK1 STK12 STK5 TAOK1 TD60 TMBS62 TXBP181 XPO1 ZW10 ZWILCH ZWINT	Homo sapiens (human)
alectinib-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK	Homo sapiens (human)
PDH complex synthesizes acetyl-CoA from PYR	Dihydrolipoyl dehydrogenase, mitochondrial Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Pyruvate dehydrogenase protein X component, mitochondrial	O00330 P08559 P09622 P10515 P11177 P29803	DLAT DLD DLTA GCSL LAD PDHA1 PDHA2 PDHAL PDHB PDHX PDX1 PHE1A PHE1B PHE3	Homo sapiens (human)
Synaptic adhesion-like molecules	Disks large homolog 1 Disks large homolog 3 Disks large homolog 4 Flotillin-1 Flotillin-2 Glutamate receptor 1 Glutamate receptor 3 Glutamate receptor 4 Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat and fibronectin type III domain-containing protein 1 Leucine-rich repeat and fibronectin type-III domain-containing protein 2 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 Leucine-rich repeat and fibronectin type-III domain-containing protein 4 Receptor-type tyrosine-protein phosphatase F Receptor-type tyrosine-protein phosphatase S Receptor-type tyrosine-protein phosphatase delta Reticulon-3	O15399 O75955 O95197 P10586 P23468 P42261 P42263 P48058 P78352 Q05586 Q12879 Q12959 Q13224 Q13332 Q14254 Q14957 Q6PJG9 Q92796 Q9BTN0 Q9P244 Q9ULH4	ASYIP DLG1 DLG3 DLG4 ESA1 FLOT1 FLOT2 GLUA1 GLUH1 GLUR1 GLUR3 GLUR4 GLURC GRIA1 GRIA3 GRIA4 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GluA3 GluA4 GluN2D KIAA1232 KIAA1246 KIAA1484 LAR LRFN1 LRFN2 LRFN3 LRFN4 M17S1 NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D NSPL2 PSD95 PTPRD PTPRF PTPRS RTN3 SALM1 SALM2 SALM3 SALM4	Homo sapiens (human)
CDK-mediated phosphorylation and removal of Cdc6	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division control protein 6 homolog Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Fizzy-related protein homolog G1/S-specific cyclin-E1 G1/S-specific cyclin-E2 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O00762 O14818 O43242 O96020 P0CG47 P0CG48 P17980 P20248 P20618 P24864 P24941 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30260 P35998 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P60006 P60896 P60900 P62191 P62195 P62333 P62979 P62987 P78396 Q13042 Q13200 Q15008 Q16186 Q16763 Q8NHZ8 Q96DE5 Q99436 Q99460 Q99741 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13 Q9UNM6	ADRM1 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C7orf76 C9orf17 CCN1 CCNA CCNA1 CCNA2 CCNE CCNE1 CCNE2 CDC16 CDC18L CDC23 CDC26 CDC27 CDC6 CDH1 CDK2 CDKN2 CENP-27 D0S1430E D17S978E DSS1 E2EPF FYR FZR FZR1 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 KIAA1242 KIAA1406 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEM1 SFT SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Z	Homo sapiens (human)
Inhibition of TSC complex formation by PKB	Hamartin RAC-beta serine/threonine-protein kinase Tuberin	P31751 P49815 Q92574	AKT2 KIAA0243 TSC TSC1 TSC2 TSC4	Homo sapiens (human)
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization	ADP/ATP translocase 1 ADP/ATP translocase 2 ADP/ATP translocase 3 Protein Vpr	P05141 P12235 P12236 P69726	AAC1 AAC2 AAC3 ANT1 ANT2 ANT3 SLC25A4 SLC25A5 SLC25A6 vpr	Homo sapiens (human)
Defective CUBN causes MGA1	Cobalamin binding intrinsic factor Cubilin Protein amnionless	O60494 P27352 Q9BXJ7	AMN CBLIF CUBN GIF IFCR IFMH	Homo sapiens (human)
Peptide ligand-binding receptors	Adrenocorticotropic hormone receptor Angiotensinogen Apelin receptor Apelin Atypical chemokine receptor 1 B1 bradykinin receptor B2 bradykinin receptor Bombesin receptor subtype-3 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 C5a anaphylatoxin chemotactic receptor 2 Cholecystokinin receptor type A Cholecystokinin Complement C3 Complement C5 Cortistatin Delta-type opioid receptor Endoplasmic reticulum membrane adapter protein XK Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Endothelin-converting enzyme 1 Endothelin-converting enzyme 2 G-protein coupled estrogen receptor 1 G-protein coupled receptor 37-like 1 Galanin peptides Galanin receptor type 1 Galanin receptor type 2 Galanin receptor type 3 Gastrin-releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Growth hormone secretagogue receptor type 1 Interleukin-8 Kappa-type opioid receptor Kell blood group glycoprotein KiSS-1 receptor Kininogen-1 Melanin-concentrating hormone receptor 1 Melanin-concentrating hormone receptor 2 Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Metastasis-suppressor KiSS-1 Motilin receptor Mu-type opioid receptor Neurolysin, mitochondrial Neuromedin-B receptor Neuromedin-B Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide B Neuropeptide S receptor Neuropeptide S Neuropeptide W Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 4 Neuropeptide Y receptor type 5 Neuropeptides B/W receptor type 1 Neuropeptides B/W receptor type 2 Neurotensin receptor type 1 Neurotensin receptor type 2 Neurotensin/neuromedin N Nociceptin receptor Pancreatic polypeptide prohormone Peptide YY Prepronociceptin Pro-MCH Pro-neuropeptide Y Pro-opiomelanocortin Pro-thyrotropin-releasing hormone Proenkephalin-A Proenkephalin-B Prokineticin receptor 1 Prokineticin receptor 2 Prokineticin-1 Prokineticin-2 Prolactin-releasing peptide receptor Prolactin-releasing peptide Promotilin Prosaposin receptor GPR37 Prosaposin Proteinase-activated receptor 1 Proteinase-activated receptor 2 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin receptor type 4 Somatostatin receptor type 5 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Type-2 angiotensin II receptor Urotensin-2 receptor Urotensin-2 Urotensin-2B	O00230 O00254 O15354 O43193 O43603 O60755 O60883 O95399 O95665 P00734 P01019 P01024 P01031 P01042 P01189 P01210 P01213 P01298 P01303 P05305 P06307 P07492 P07602 P08949 P0C0P6 P0DPD6 P10082 P10145 P12872 P14138 P20382 P20396 P20800 P21730 P22466 P23276 P24530 P25101 P25116 P25929 P28336 P30411 P30550 P30556 P30872 P30874 P30989 P30990 P31391 P32238 P32239 P32245 P32247 P32745 P33032 P34981 P35346 P35372 P35414 P41143 P41145 P41146 P41968 P42892 P46663 P47211 P48145 P48146 P48645 P49146 P49683 P50052 P50391 P51811 P55085 P58294 P61278 P81277 Q01718 Q01726 Q13519 Q15726 Q15761 Q16570 Q16581 Q5H8A3 Q6W5P4 Q765I0 Q8N729 Q8NFJ6 Q8NG41 Q8TCW9 Q92847 Q969F8 Q969V1 Q96RI0 Q99527 Q99705 Q9BYT8 Q9GZQ4 Q9HB89 Q9HC23 Q9P296 Q9UKP6 Q9ULZ1	ACKR1 ACTHR AGT AGTBP AGTR1 AGTR1A AGTR1B AGTR2 AGTRL1 APEL APJ APLN APLNR AT2R1 AT2R1B AXOR12 AZ3B BDK BDKRB1 BDKRB2 BKR2 BRADYB1 BRS3 BV8 C3 C3AR1 C3R1 C5 C5AR C5AR1 C5AR2 C5L2 C5R1 CCK CCKAR CCKBR CCKRA CCKRB CEPR CF2R CMKRL2 CORT CPAMD1 CPAMD4 CXCL8 DARC DRY12 ECE1 ECE2 EDN1 EDN2 EDN3 EDNRA EDNRB ETA ETBRLP2 ETRA ETRB F2 F2R F2RL1 F2RL2 F2RL3 FY GAL GAL1 GALN GALNR GALNR1 GALNR2 GALNR3 GALR1 GALR2 GALR3 GHSR GLBA GLNN GPD GPER GPER1 GPR10 GPR11 GPR14 GPR145 GPR154 GPR24 GPR30 GPR37 GPR37L1 GPR38 GPR54 GPR66 GPR7 GPR73 GPR73L1 GPR77 GPR8 GPRA GR3 GRP GRPR HNFAG09 IL8 KEL KIAA0604 KIAA1226 KISS1 KISS1R KNG KNG1 MC1R MC2R MC3R MC4R MC5R MCH MCHR1 MCHR2 MLN MLNR MOR1 MSHR MTLR MTLR1 NLN NMB NMBR NMS NMU NMU2R NMUR1 NMUR2 NPB NPBWR1 NPBWR2 NPS NPSR1 NPW NPY NPY1R NPY2R NPY4R NPY5R NPYR NPYR5 NPYY1 NTRR NTS NTSR1 NTSR2 OFQ OOR OPRD OPRD1 OPRK OPRK1 OPRL1 OPRM1 ORL1 PAR1 PAR2 PAR3 PAR4 PDYN PENK PGR14 PKR1 PKR2 PMCH PNOC PNP POMC PPL7 PPL8 PPNPB PPNPW PPY PPYR1 PRH PRLH PRLHR PROK1 PROK2 PROKR1 PROKR2 PSAP PYY SAP1 SERPINA8 SLC1 SLT SST SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 TGR1 TR TRH TRHR URP UTS2 UTS2B UTS2D UTS2R XK XKR1 XRG1	Homo sapiens (human)
Phosphorylation of the APC/C	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S	O00762 P06493 P14635 P30260 P51668 P51965 P53350 P60006 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CCNB CCNB1 CDC16 CDC2 CDC23 CDC26 CDC27 CDC28A CDK1 CDKN1 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 P34CDC2 PLK PLK1 SFT TSG24 UBC5A UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	14-3-3 protein beta/alpha 5'-3' exoribonuclease 1 Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 MAP kinase-activated protein kinase 2 Transportin-1 m7GpppN-mRNA hydrolase mRNA decay activator protein ZFP36 mRNA-decapping enzyme 1A	P26651 P31946 P49137 Q06265 Q13868 Q15024 Q5RKV6 Q8IU60 Q8IZH2 Q92973 Q96B26 Q9NPD3 Q9NPI6 Q9NQT4 Q9NQT5 Q9Y2L1 Q9Y3B2	CML28 CSL4 DCP1A DCP2 DIS3 EXOSC1 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 G0S24 KIAA0116 KIAA1008 KPNB2 MAPKAPK2 MIP1 MTR3 NUDT20 NUP475 OIP2 PMSCL1 RNF162A RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 SEP1 SKI6 SMIF TIS11A TNPO1 TRN TTP XRN1 YWHAB ZFP36	Homo sapiens (human)
Signaling downstream of RAS mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB	Homo sapiens (human)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase SMURF1 Junctional adhesion molecule A Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Peptidyl-prolyl cis-trans isomerase FKBP1A Polyubiquitin-B Polyubiquitin-C Protein kinase C zeta type Rho guanine nucleotide exchange factor 18 TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P01137 P0CG47 P0CG48 P36897 P37173 P61586 P62942 P62979 P62987 Q05513 Q6ZSZ5 Q8TEW0 Q9HCE7 Q9NPB6 Q9P2M7 Q9Y624	ALK5 ARH12 ARHA ARHGEF18 CGN F11R FKBP1 FKBP12 FKBP1A JAM1 JCAM KIAA0521 KIAA1319 KIAA1625 PAR3 PAR3A PAR6A PARD3 PARD6A PKC2 PRKCZ RHO12 RHOA RPS27A SKR4 SMURF1 TGFB TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
NFG and proNGF binds to p75NTR	Beta-nerve growth factor Sortilin-related VPS10 domain containing receptor 3 Tumor necrosis factor receptor superfamily member 16	P01138 P08138 Q17R88	NGF NGFB NGFR SORCS3 TNFRSF16	Homo sapiens (human)
SMAC (DIABLO) binds to IAPs	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP	Homo sapiens (human)
Synthesis of Ketone Bodies	3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic Acetoacetyl-CoA synthetase Acetyl-CoA acetyltransferase, mitochondrial Acyl-CoA synthetase short-chain family member 3, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Dehydrogenase/reductase SDR family member 6 Hydroxymethylglutaryl-CoA lyase, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial	P24752 P35914 P54868 Q02338 Q86V21 Q8TB92 Q9BUT1 Q9H6R3	AACS ACAT ACAT1 ACSF1 ACSS3 BDH BDH1 BDH2 DHRS6 HMGCL HMGCLL1 HMGCS2 MAT SDR15C1 SDR9C1	Homo sapiens (human)
Sunitinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Defective ABCC8 can cause hypo- and hyper-glycemias	ATP-binding cassette sub-family C member 8 ATP-sensitive inward rectifier potassium channel 11	Q09428 Q14654	ABCC8 HRINS KCNJ11 SUR SUR1	Homo sapiens (human)
NOTCH2 Activation and Transmission of Signal to the Nucleus	Contactin-1 Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Midkine Neurogenic locus notch homolog protein 2 Nicastrin Notch homolog 2 N-terminal-like protein A Notch homolog 2 N-terminal-like protein B Notch homolog 2 N-terminal-like protein C Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Protein jagged-1 Protein jagged-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O76050 P0CG47 P0CG48 P0DPK3 P0DPK4 P21741 P49768 P49810 P62979 P62987 P78504 Q04721 Q12860 Q7Z3S9 Q86YT6 Q8WW43 Q92542 Q96AX9 Q96BI3 Q9NR61 Q9NZ42 Q9Y219	AD3 AD4 ADAM10 APH1A APH1B CNTN1 DIP1 DLL1 DLL4 JAG1 JAG2 JAGL1 KIAA0253 KIAA1323 KUZ MADM MDK MIB1 MIB2 MK1 N2N NCSTN NEGF2 NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH2 NOTCH2NL NOTCH2NLA NOTCH2NLB NOTCH2NLC PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF67 RPS27A SKD STM2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2	Homo sapiens (human)
Dectin-2 family	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 C-type lectin domain family 10 member A C-type lectin domain family 4 member A C-type lectin domain family 4 member C C-type lectin domain family 4 member D C-type lectin domain family 4 member E C-type lectin domain family 6 member A Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Envelope glycoprotein gp160 Genome polyprotein High affinity immunoglobulin epsilon receptor subunit gamma Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1 Truncated surface protein Truncated surface protein Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK	P03375 P03377 P03378 P04578 P04579 P04580 P04581 P04582 P04583 P04624 P05877 P05878 P05879 P05880 P05881 P05882 P06241 P07948 P12487 P12488 P12489 P12490 P12491 P15941 P16885 P18799 P19549 P19550 P19551 P20871 P20888 P30273 P31819 P31872 P35961 P43405 P98088 Q02505 Q02817 Q5SSG8 Q685J3 Q6EIG7 Q6W4X9 Q70626 Q7Z5P9 Q8IUN9 Q8N307 Q8N387 Q8TAX7 Q8WTT0 Q8WXI7 Q8WXI8 Q96DR8 Q99102 Q99IB8 Q9H195 Q9H3R2 Q9HC84 Q9UKN1 Q9ULY5 Q9UMR7	BDCA2 C6orf205 CA125 CLEC10A CLEC4A CLEC4C CLEC4D CLEC4E CLEC6A CLECSF10 CLECSF11 CLECSF13 CLECSF14 CLECSF6 CLECSF7 CLECSF8 CLECSF9 DCIR DECTIN2 DLEC DRCC1 FCER1G FYN HECL HML JTK8 KIAA1359 LLIR LYN MCL MG2 MINCLE MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 PLCG2 PUM RECC SBEM SMUC SYK env	Homo sapiens (human)
IRS activation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin	P01308 P06213 P35568 Q13322 Q9Y4H2	GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207	Homo sapiens (human)
IRF3 mediated activation of type 1 IFN	E3 ubiquitin-protein ligase DTX4 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Serine/threonine-protein kinase TBK1 Z-DNA-binding protein 1	Q14653 Q96MN2 Q9H171 Q9UHD2 Q9Y2E6	C20orf183 DLM1 DTX4 IRF3 KIAA0937 NAK NALP4 NLRP4 PAN2 PYPAF4 RNF155 RNH2 TBK1 ZBP1	Homo sapiens (human)
CLEC7A (Dectin-1) induces NFAT activation	Calcineurin subunit B type 1 Calmodulin-1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 2 Nuclear factor of activated T-cells, cytoplasmic 3 Protein phosphatase 3 catalytic subunit alpha S-adenosylhomocysteine hydrolase-like protein 1 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform	O43865 O95644 P0DP23 P16298 P63098 Q08209 Q12968 Q13469 Q14571 Q14573 Q14643	AHCYL1 CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CNA CNA2 CNB DCAL INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 NFAT1 NFAT2 NFAT4 NFATC NFATC1 NFATC2 NFATC3 NFATP PPP3CA PPP3CB PPP3R1 XPVKONA	Homo sapiens (human)

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