GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1626 - 1650** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23	Q9GZV9	FGF23 HYPF	Homo sapiens (human)
Activation of the phototransduction cascade	Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Sodium/potassium/calcium exchanger 1	O60721 P08100 P10523 P11488 P16499 P18545 P29973 P35913 P62873 P63211 Q14028	CNCG CNCG1 CNCG2 CNCG3L CNCG4 CNGA1 CNGB1 GNAT1 GNATR GNB1 GNGT1 KIAA0702 NCKX1 OPN2 PDE6A PDE6B PDE6G PDEA PDEB PDEG RCNC2 RHO SAG SLC24A1	Homo sapiens (human)
Interferon gamma signaling	2'-5'-oligoadenylate synthase 1 2'-5'-oligoadenylate synthase 2 2'-5'-oligoadenylate synthase 3 2'-5'-oligoadenylate synthase-like protein Beta-2-microglobulin CD44 antigen Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma E3 ubiquitin-protein ligase Midline-1 E3 ubiquitin-protein ligase TRIM17 E3 ubiquitin-protein ligase TRIM21 E3 ubiquitin-protein ligase TRIM22 E3 ubiquitin-protein ligase TRIM31 E3 ubiquitin-protein ligase TRIM34 E3 ubiquitin-protein ligase TRIM35 E3 ubiquitin-protein ligase TRIM38 E3 ubiquitin-protein ligase TRIM45 E3 ubiquitin-protein ligase TRIM48 E3 ubiquitin-protein ligase TRIM62 E3 ubiquitin-protein ligase TRIM68 E3 ubiquitin-protein ligase TRIM8 E3 ubiquitin/ISG15 ligase TRIM25 Gamma-interferon-inducible lysosomal thiol reductase Guanylate-binding protein 1 Guanylate-binding protein 2 Guanylate-binding protein 3 Guanylate-binding protein 4 Guanylate-binding protein 5 Guanylate-binding protein 6 Guanylate-binding protein 7 HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain High affinity immunoglobulin gamma Fc receptor I Intercellular adhesion molecule 1 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Interferon regulatory factor 1 Interferon regulatory factor 2 Interferon regulatory factor 3 Interferon regulatory factor 4 Interferon regulatory factor 5 Interferon regulatory factor 6 Interferon regulatory factor 7 Interferon regulatory factor 8 Interferon regulatory factor 9 MHC class II transactivator Metallothionein-2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 7 Neural cell adhesion molecule 1 Nuclear autoantigen Sp-100 Platelet-activating factor receptor Protein PML Protein kinase C delta type Putative HLA class I histocompatibility antigen, alpha chain H Putative high affinity immunoglobulin gamma Fc receptor IB Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tripartite motif-containing protein 10 Tripartite motif-containing protein 14 Tripartite motif-containing protein 26 Tripartite motif-containing protein 29 Tripartite motif-containing protein 2 Tripartite motif-containing protein 3 Tripartite motif-containing protein 46 Tripartite motif-containing protein 5 Tripartite motif-containing protein 6 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 6 Vascular cell adhesion protein 1 Y-box-binding protein 1	O00635 O14543 O14896 O15105 O15344 O15524 O60674 O75382 P00973 P01579 P01889 P01893 P01903 P01906 P01909 P01911 P01920 P02795 P04439 P04440 P05362 P05538 P10321 P10914 P12314 P13284 P13591 P13747 P13762 P14316 P15260 P16070 P17693 P19320 P19474 P20036 P23458 P23497 P25105 P27361 P28482 P29350 P29590 P29728 P30511 P32455 P32456 P33076 P38484 P61769 P67809 P79483 Q00978 Q02556 Q05655 Q12899 Q13554 Q13555 Q13557 Q13568 Q14134 Q14142 Q14258 Q14653 Q15306 Q15646 Q30154 Q6AZZ1 Q6ZN66 Q7Z4K8 Q8IWZ4 Q8IYM9 Q8N8V2 Q92637 Q92985 Q96PP8 Q96PP9 Q9BVG3 Q9BYJ4 Q9BZR9 Q9BZY9 Q9C030 Q9C035 Q9C040 Q9H0R5 Q9H8W5 Q9UDY6 Q9UPQ4 Q9UQM7 Q9Y577 Q9Y6K5	ATDC B2M BERP C6orf13 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CD44 CES1 CIITA CIS3 EFP ERK1 ERK2 FCG1 FCGR1 FCGR1A FCGR1B FCGR1BP FXY GBP1 GBP2 GBP3 GBP4 GBP4L GBP5 GBP6 GBP7 GC109 GERP GILT HCP HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HLASB HLS5 ICAM1 ICSBP1 IFI30 IFNG IFNGR1 IFNGR2 IFNGT1 IFP1 IGFR1 IGFRB IP30 IRF1 IRF2 IRF3 IRF4 IRF5 IRF6 IRF7 IRF8 IRF9 ISGF3G JAK1 JAK1A JAK1B JAK2 KIAA0129 KIAA0517 KIAA0968 KIAA1098 LHR MADH7 MADH8 MAPK1 MAPK3 MDU2 MDU3 MHC2TA MIC4 MID1 MT2 MT2A MUM1 MYL NCAM NCAM1 NSEP1 OAS1 OAS2 OAS3 OASL OIAS PAFR PKCD PML PP8675 PRKCD PRKM1 PRKM2 PRKM3 PTAFR PTP1C PTPN6 RBCC RFB30 RNF RNF101 RNF137 RNF147 RNF15 RNF16 RNF21 RNF22 RNF27 RNF59 RNF71 RNF81 RNF86 RNF88 RNF89 RNF9 RNF94 RNF95 RNF97 RNF99 RO52 RORET SMAD7 SOCS1 SOCS3 SP100 SS56 SSA1 SSI1 SSI3 STAF50 TERF TIP3 TRIFIC TRIM10 TRIM14 TRIM17 TRIM18 TRIM19 TRIM2 TRIM21 TRIM22 TRIM25 TRIM26 TRIM29 TRIM3 TRIM31 TRIM34 TRIM35 TRIM38 TRIM45 TRIM46 TRIM48 TRIM5 TRIM6 TRIM62 TRIM68 TRIM8 TRIP14 VCAM1 XPRF YB1 YBX1 ZNF147 ZNF173	Homo sapiens (human)
Regulation of PTEN mRNA translation	Helicase MOV-10 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	P60484 Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 CAGH26 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MMAC1 MOV10 PTEN TEP1 TNRC6 TNRC6A TNRC6B TNRC6C	Homo sapiens (human)
O-linked glycosylation	Beta-1,4-glucuronyltransferase 1 Dystroglycan 1 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Protein O-mannose kinase Protein O-mannosyl-transferase 1 Protein O-mannosyl-transferase 2 UDP-GalNAc Xylosyl- and glucuronyltransferase LARGE1 Xylosyl- and glucuronyltransferase LARGE2	O43505 O95461 Q14118 Q8N3Y3 Q8NAT1 Q8NCR0 Q8WZA1 Q9H5K3 Q9UKY4 Q9Y6A1	AGO61 B3GALNT2 B3GNT1 B3GNT6 B4GAT1 C3orf39 DAG1 EOGTL GTDC2 GYLTL1B KIAA0609 LARGE LARGE1 LARGE2 MGAT1.2 POMGNT1 POMGNT2 POMK POMT1 POMT2 SGK196	Homo sapiens (human)
Toxicity of botulinum toxin type F (botF)	Botulinum neurotoxin type F Synaptic vesicle glycoprotein 2A Synaptic vesicle glycoprotein 2B Synaptic vesicle glycoprotein 2C Vesicle-associated membrane protein 1 Vesicle-associated membrane protein 2	P23763 P30996 P63027 Q496J9 Q7L0J3 Q7L1I2	KIAA0735 KIAA0736 KIAA1054 SV2A SV2B SV2C SYB1 SYB2 VAMP1 VAMP2 botF	Homo sapiens (human)
APC/C:Cdc20 mediated degradation of Cyclin B	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 Polyubiquitin-B Polyubiquitin-C Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 P06493 P0CG47 P0CG48 P14635 P30260 P51668 P51965 P60006 P62979 P62987 Q12834 Q13042 Q16763 Q8NHZ8 Q96DE5 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 C10orf104 C11orf51 C9orf17 CCNB CCNB1 CDC16 CDC2 CDC20 CDC23 CDC26 CDC27 CDC28A CDK1 CDKN1 CENP-27 D0S1430E D17S978E E2EPF KIAA1406 P34CDC2 RPS27A SFT TSG24 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S	Homo sapiens (human)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	3-phosphoinositide-dependent protein kinase 1 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Cadherin-5 Calcitonin gene-related peptide type 1 receptor Calmodulin-1 Calpain small subunit 1 Calpain small subunit 2 Calpain-2 catalytic subunit Catenin beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Matrix metalloproteinase-14 Nitric oxide synthase 3 P2Y purinoceptor 2 Pannexin-1 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Piezo-type mechanosensitive ion channel component 1 Platelet endothelial cell adhesion molecule Pro-adrenomedullin Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Receptor activity-modifying protein 2 Serine/threonine-protein kinase N2 Serine/threonine-protein kinase mTOR Talin-1 Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Transient receptor potential cation channel subfamily V member 4 Tyrosine-protein kinase Fyn Vascular endothelial growth factor receptor 2 Vascular endothelial growth factor receptor 3 Vinculin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O00329 O00459 O14610 O14775 O15530 O43306 O60262 O60266 O60503 O60895 O95622 P04632 P06241 P0DP23 P10644 P13861 P16284 P16520 P17612 P17655 P18206 P22612 P22694 P29474 P29992 P31321 P31323 P31749 P33151 P35222 P35318 P35916 P35968 P40145 P41231 P42336 P42338 P42345 P50148 P50150 P50151 P50281 P51828 P59768 P61952 P62873 P62879 P63092 P63211 P63215 P63218 P85299 Q08462 Q08828 Q16513 Q16602 Q5JWF2 Q6R327 Q8NFM4 Q92508 Q96L46 Q96RD7 Q9BPZ7 Q9BVC4 Q9HAV0 Q9HBA0 Q9P2W3 Q9UBI6 Q9UK08 Q9Y490	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADM AKT1 AM CALCRL CALM CALM1 CAM CAM1 CANPL2 CAPN2 CAPN4 CAPNS CAPNS1 CAPNS2 CDH5 CGRPR CTNNB CTNNB1 FAM38A FLK1 FLT4 FRAP FRAP1 FRAP2 FYN GA11 GAQ GBL GNA11 GNAQ GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KDR KIAA0037 KIAA0233 KIAA0422 KIAA0511 KIAA0520 KIAA1027 KIAA1060 KIAA1999 LST8 MAPKAP1 MIP1 MLST8 MMP14 MRS1 MTOR NOS3 P2RU1 P2RY2 PANX1 PDK1 PDPK1 PECAM1 PIEZO1 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R2 PKACA PKB PKN2 PKR1 PKR2 PRK2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKCL2 PROTOR1 PRR5 RAC RAFT1 RAMP2 RAPT1 RICTOR SIN1 TLN TLN1 TRPV4 TSE1 VCL VEGFR2 VEGFR3 VRL2 VROAC	Homo sapiens (human)
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta-1 Tensin-3 Tensin-4	P05556 P08581 P14210 Q68CZ2 Q8IZW8	CTEN FNRB HGF HPTA ITGB1 MDF2 MET MSK12 TEM6 TENS1 TNS3 TNS4 TPP	Homo sapiens (human)
Formation of the Early Elongation Complex	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 P13984 P18074 P18615 P19387 P19388 P19447 P24928 P30876 P32780 P35269 P36954 P50613 P51946 P51948 P52298 P52434 P52435 P53803 P61218 P62487 P62875 P63272 Q09161 Q13888 Q13889 Q6ZYL4 Q8IXH7 Q8WX92 Q92759 Q9H3P2 Q9Y5B0	BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CDK7 CDKN7 COBRA1 CTDP1 ERCC2 ERCC3 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 KIAA1182 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H STK1 SUPT4H SUPT4H1 SUPT5H TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC	Homo sapiens (human)
G beta:gamma signalling through PLC beta	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q00722 Q01970 Q9HAV0 Q9NQ66 Q9P2W3 Q9UBI6 Q9UK08	GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0581 PLCB1 PLCB2 PLCB3	Homo sapiens (human)
PD-1 signaling	HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Programmed cell death 1 ligand 1 Programmed cell death 1 ligand 2 Programmed cell death protein 1 T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase CSK Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	A0A0A6YYK7 P01730 P01733 P01737 P01848 P01850 P01903 P01906 P01909 P01911 P01920 P04234 P04435 P04437 P04440 P05538 P06239 P07766 P09693 P13762 P20036 P29350 P41240 P79483 Q06124 Q15116 Q30154 Q9BQ51 Q9NZQ7	B7DC B7H1 CD273 CD274 CD3D CD3E CD3G CD4 CSK HCP HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLASB LCK PD1 PDCD1 PDCD1L1 PDCD1L2 PDCD1LG1 PDCD1LG2 PDL1 PDL2 PTP1C PTP2C PTPN11 PTPN6 SHPTP2 T3D T3E T3G TCRA TCRBV12S3 TCRBV8S1 TRAC TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9	Homo sapiens (human)
Influenza Virus Induced Apoptosis	ADP/ATP translocase 3 Neuraminidase Protein PB1-F2 Transforming growth factor beta-1 proprotein	P01137 P03468 P0C0U1 P12236	AAC3 ANT3 NA PB1 SLC25A6 TGFB TGFB1	Homo sapiens (human)
Defective B4GALT1 causes CDG-2d	Beta-1,4-galactosyltransferase 1	P15291	B4GALT1 GGTB2	Homo sapiens (human)
Molecules associated with elastic fibres	Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein 4 Bone morphogenetic protein 7 EGF-containing fibulin-like extracellular matrix protein 1 EGF-containing fibulin-like extracellular matrix protein 2 Fibulin-1 Fibulin-2 Fibulin-5 Growth/differentiation factor 5 Integrin alpha-8 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-5 Integrin beta-6 Integrin beta-8 Latent-transforming growth factor beta-binding protein 1 Latent-transforming growth factor beta-binding protein 2 Latent-transforming growth factor beta-binding protein 3 Latent-transforming growth factor beta-binding protein 4 Microfibril-associated glycoprotein 3 Microfibril-associated glycoprotein 4 Microfibrillar-associated protein 2 Microfibrillar-associated protein 5 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta-3 proprotein Vitronectin	O95393 O95967 P01137 P04004 P05106 P05556 P06756 P10600 P12643 P12644 P18075 P18084 P18564 P23142 P26012 P43026 P53708 P55001 P55082 P55083 P61812 P98095 Q12805 Q13361 Q14766 Q14767 Q8N2S1 Q9NS15 Q9UBX5	BMP10 BMP14 BMP2 BMP2A BMP2B BMP4 BMP7 C14orf141 CDMP1 DANCE DVR4 EFEMP1 EFEMP2 FBLN1 FBLN2 FBLN3 FBLN4 FBLN5 FBNL FNRB GDF5 GP3A ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP2 LTBP3 LTBP4 MAGP1 MAGP2 MDF2 MFAP2 MFAP3 MFAP4 MFAP5 MSK12 MSK8 OP1 TGFB TGFB1 TGFB2 TGFB3 VNRA VTN VTNR	Homo sapiens (human)
p53-Dependent G1 DNA Damage Response	Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E1 G1/S-specific cyclin-E2	O96020 P20248 P24864 P24941 P38936 P46527 P78396	CAP20 CCN1 CCNA CCNA1 CCNA2 CCNE CCNE1 CCNE2 CDK2 CDKN1 CDKN1A CDKN1B CDKN2 CIP1 KIP1 MDA6 PIC1 SDI1 WAF1 p27	Homo sapiens (human)
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	Sodium- and chloride-dependent transporter XTRP3	Q9NP91	SIT1 SLC6A20 XT3 XTRP3	Homo sapiens (human)
Metallothioneins bind metals	Metallothionein-1A Metallothionein-1B Metallothionein-1E Metallothionein-1F Metallothionein-1G Metallothionein-1H Metallothionein-1M Metallothionein-1X Metallothionein-2 Metallothionein-3 Metallothionein-4	P02795 P04731 P04732 P04733 P07438 P13640 P25713 P47944 P80294 P80297 Q8N339	CES1 MT1A MT1B MT1E MT1F MT1G MT1H MT1K MT1M MT1Q MT1S MT1X MT2 MT2A MT3 MT4	Homo sapiens (human)
NTF4 activates NTRK2 (TRKB) signaling	BDNF/NT-3 growth factors receptor Neurotrophin-4	P34130 Q16620	NTF4 NTF5 NTRK2 TRKB	Homo sapiens (human)
Resistance of ERBB2 KD mutants to neratinib	Erbin Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Receptor tyrosine-protein kinase erbB-2	P04626 P07900 Q16543 Q96RT1	CDC37 CDC37A ERBB2 ERBB2IP ERBIN HER2 HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NEU NGL	Homo sapiens (human)
Beta-oxidation of very long chain fatty acids	3-ketoacyl-CoA thiolase, peroxisomal ATP-binding cassette sub-family D member 1 Acyl-coenzyme A thioesterase 8 Long-chain fatty acid transport protein 2 Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal bifunctional enzyme Peroxisomal multifunctional enzyme type 2 Peroxisomal succinyl-coenzyme A thioesterase	O14734 O14975 P09110 P33897 P51659 Q08426 Q8N9L9 Q9NUI1	ABCD1 ACAA ACAA1 ACOT4 ACOT8 ACSVL1 ACTEIII ALD DECR2 ECHD EDH17B4 EHHADH FACVL1 FATP2 HSD17B4 PDCR PTE1 PTE2B PTEIB PTHIO SDR17C1 SDR8C1 SLC27A2 VLACS	Homo sapiens (human)
Apoptotic execution phase	B-cell receptor-associated protein 31 Caspase-8 Dynamin-1-like protein Serine/threonine-protein kinase 24	O00429 P51572 Q14790 Q9Y6E0	BAP31 BCAP31 CASP8 DLP1 DNM1L DRP1 DXS1357E MCH5 MST3 STK24 STK3	Homo sapiens (human)
Cellular hexose transport	Fibroblast growth factor 21 Probable glucose sensor protein SLC5A4 Sodium-dependent glucose transporter 1 Sodium/glucose cotransporter 1 Sodium/glucose cotransporter 2 Sodium/glucose cotransporter 4 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 11 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 14 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 2, facilitated glucose transporter member 6 Solute carrier family 2, facilitated glucose transporter member 7 Solute carrier family 2, facilitated glucose transporter member 8 Solute carrier family 2, facilitated glucose transporter member 9 Solute carrier family 45 member 3 Sugar transporter SWEET1	A0PJK1 O95528 P11166 P11168 P11169 P13866 P14672 P31639 Q2M3M2 Q5TF39 Q6PXP3 Q8TD20 Q8TDB8 Q96JT2 Q9BRV3 Q9BYW1 Q9NRM0 Q9NSA1 Q9NY64 Q9NY91 Q9UGQ3	FGF21 GLUT1 GLUT10 GLUT11 GLUT12 GLUT14 GLUT2 GLUT3 GLUT4 GLUT6 GLUT7 GLUT8 GLUT9 GLUTX1 KIAA1919 MFSD4B NAGLT1 NAGT PCANAP6 PRST RAG1AP1 SAAT1 SCP SGLT1 SGLT2 SGLT3 SGLT4 SGLT5 SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A14 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A7 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Homo sapiens (human)	G58161NS G70323CJ
Nilotinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Gamma-carboxylation of protein precursors	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent gamma-carboxylase Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P22891 P38435 Q14393	AXLLG BGLAP F10 F2 F7 F9 GAS6 GC GGCX PROC PROS PROS1 PROZ	Homo sapiens (human)

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