GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **776 - 800** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
MET Receptor Activation	Hepatocyte growth factor activator Hepatocyte growth factor receptor Hepatocyte growth factor Kunitz-type protease inhibitor 1 Kunitz-type protease inhibitor 2 Serine protease hepsin	O43278 O43291 P05981 P08581 P14210 Q04756	HAI1 HAI2 HGF HGFAC HPN HPTA KOP MET SPINT1 SPINT2 TMPRSS1	Homo sapiens (human)
Non-integrin membrane-ECM interactions	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Discoidin domain-containing receptor 2 Dystroglycan 1 Dystrophin Epithelial discoidin domain-containing receptor 1 Fibroblast growth factor 2 Laminin subunit alpha-1 Laminin subunit alpha-2 Laminin subunit alpha-3 Laminin subunit alpha-4 Laminin subunit alpha-5 Laminin subunit beta-1 Laminin subunit beta-2 Laminin subunit beta-3 Laminin subunit gamma-1 Laminin subunit gamma-2 Laminin subunit gamma-3 Netrin-4 Neurexin-1 Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Transthyretin	O00468 O15230 P01127 P02766 P04085 P07942 P09038 P11047 P11532 P24043 P25391 P55268 P98160 Q08345 Q13751 Q13753 Q14118 Q16363 Q16787 Q16832 Q9HB63 Q9ULB1 Q9Y6N6	AGRIN AGRN CAK DAG1 DDR1 DDR2 DMD EDDR1 FGF2 FGFB HSPG2 KIAA0533 KIAA0578 KIAA1907 LAMA LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB2T LAMB3 LAMC1 LAMC2 LAMC3 LAMM LAMNA LAMNB1 LAMNB2 LAMS NEP NRXN1 NTN4 NTRK4 NTRKR3 PALB PDGF1 PDGF2 PDGFA PDGFB PTK3A RTK6 SIS TKT TRKE TTR TYRO10	Homo sapiens (human)
VEGFR2 mediated cell proliferation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3-phosphoinositide-dependent protein kinase 1 Calmodulin-1 GTPase HRas GTPase NRas Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C zeta type Ras GTPase-activating protein 1 S-adenosylhomocysteine hydrolase-like protein 1 Sphingosine kinase 1 Vascular endothelial growth factor receptor 2	O15530 O43865 P01111 P01112 P05771 P0DP23 P17252 P19174 P20936 P35968 Q05513 Q05655 Q14571 Q14573 Q14643 Q9NYA1	AHCYL1 CALM CALM1 CAM CAM1 DCAL FLK1 GAP HRAS HRAS1 INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KDR NRAS PDK1 PDPK1 PKC2 PKCA PKCB PKCD PLC1 PLCG1 PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCZ RASA RASA1 SK1 SPHK SPHK1 SPK VEGFR2 XPVKONA	Homo sapiens (human)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Core-binding factor subunit beta Erythroid transcription factor Helicase MOV-10 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2B Histone acetyltransferase p300 Histone deacetylase 1 Histone-lysine N-methyltransferase 2A Histone-lysine N-methyltransferase 2B Histone-lysine N-methyltransferase 2C Histone-lysine N-methyltransferase 2D Histone-lysine N-methyltransferase SETD1A Histone-lysine N-methyltransferase SETD1B Integrin alpha-IIb Myosin regulatory light polypeptide 9 Nuclear receptor subfamily 4 group A member 3 Paired amphipathic helix protein Sin3a Paired amphipathic helix protein Sin3b Platelet factor 4 Platelet glycoprotein Ib alpha chain Protein arginine N-methyltransferase 1 Protein arginine N-methyltransferase 6 Protein argonaute-1 Protein argonaute-3 Protein argonaute-4 Protein dpy-30 homolog Protein kinase C theta type Retinoblastoma-binding protein 5 Runt-related transcription factor 1 Set1/Ash2 histone methyltransferase complex subunit ASH2 Thrombospondin-1 Transcription factor NF-E2 45 kDa subunit Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein WD repeat-containing protein 5 Zinc finger protein ZFPM1	O14686 O15047 O60814 O75182 P02776 P04908 P06899 P07359 P07996 P08514 P0C5Y9 P15976 P16104 P20671 P23527 P24844 P33778 P57053 P58876 P61964 P62805 P62807 P68431 P84243 Q01196 Q03164 Q04759 Q09472 Q13547 Q13951 Q15291 Q16621 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8IX07 Q8N257 Q8NDV7 Q8NEZ4 Q92570 Q92831 Q93077 Q93079 Q96A08 Q96LA8 Q96ST3 Q99873 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9C005 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UBL3 Q9UL18 Q9UMN6 Q9UPQ9 Q9UPS6	AGO1 AGO3 AGO4 ALL1 ALR AML1 ASH2L ASH2L1 BIG3 CAGH26 CBFA2 CBFB CHN CSMF CXCL4 CXXC7 DPY30 EIF2C1 EIF2C3 EIF2C4 EP300 ERYF1 FOG1 GATA1 GF1 GP1BA GP2B H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HALR HDAC1 HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HMT2 HRMT1L2 HRMT1L6 HRX HRX2 HTRX IR1B4 ITGA2B ITGAB KAT2B KIAA0304 KIAA0339 KIAA0700 KIAA1076 KIAA1093 KIAA1460 KIAA1506 KIAA1567 KIAA1582 KIAA1631 KMT2A KMT2B KMT2C KMT2D KMT2F KMT2G MINOR MLC2 MLL MLL1 MLL2 MLL3 MLL4 MOV10 MRLC1 MYL9 MYRL2 NFE2 NOR1 NR4A3 P300 PCAF PF4 PRKCQ PRKCT PRMT1 PRMT6 RBBP5 RBQ3 RPD3L1 RUNX1 SCYB4 SET1 SET1A SET1B SETD1A SETD1B SIN3A SIN3B TEC THBS1 TNRC6 TNRC6A TNRC6B TNRC6C TRX1 TRX2 TSH2B TSP TSP1 WBP7 WDR5 ZFN89A ZFPM1	Homo sapiens (human)
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin-B1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein R-Ras Rho GTPase-activating protein 35 Rho-related GTP-binding protein Rho6 Semaphorin-4D Transforming protein RhoA	O43157 P08581 P10301 P61586 P63000 Q92730 Q92854 Q9NRY4	ARH12 ARHA ARHGAP35 C9orf164 CD100 GRF1 GRLF1 KIAA0407 KIAA1722 MET P190A PLXN5 PLXNB1 RAC1 RHO12 RHO6 RHOA RND1 RRAS SEMA4D SEMAJ SEP TC25 p190ARHOGAP	Homo sapiens (human)
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	Aladin E3 SUMO-protein ligase RanBP2 Glucokinase regulatory protein Hexokinase-4 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog mRNA export factor RAE1	A8CG34 O15504 O75694 P12270 P35557 P35658 P37198 P49790 P49792 P55735 P57740 P78406 Q12769 Q14397 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E GCK GCKR KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR	Homo sapiens (human)
TGFBR3 expression	Helicase MOV-10 Histone acetyltransferase p300 Krueppel-like factor 16 Lymphoid-specific helicase Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Myoblast determination protein 1 Myogenic factor 5 Myogenic factor 6 Myogenin N-myc proto-oncogene protein Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Retinoic acid receptor RXR-alpha Retinoic acid receptor alpha Transcription factor 12 Transcription factor 4 Transcription factor E2-alpha Transcription factor Sp1 Transforming growth factor beta receptor type 3 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	P04198 P08047 P10276 P13349 P15172 P15173 P15884 P15923 P19793 P23409 P84022 Q03167 Q09472 Q13485 Q8NDV7 Q99081 Q9BXK1 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9NRZ9 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 BHLHB19 BHLHB20 BHLHB21 BHLHC1 BHLHC2 BHLHC3 BHLHC4 BHLHE37 BTEB4 CAGH26 DPC4 E2A EIF2C1 EIF2C2 EIF2C3 EIF2C4 EP300 HEB HELLS HTF4 ITF1 ITF2 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KLF16 MADH3 MADH4 MOV10 MRF4 MYCN MYF3 MYF4 MYF5 MYF6 MYOD MYOD1 MYOG NMYC NR1B1 NR2B1 NSLP2 P300 PASG RARA RXRA SEF2 SMAD3 SMAD4 SMARCA6 SP1 TCF12 TCF3 TCF4 TGFBR3 TNRC6 TNRC6A TNRC6B TNRC6C TSFP1	Homo sapiens (human)
Triglyceride catabolism	1-acylglycerol-3-phosphate O-acyltransferase ABHD5 Caveolin-1 Fatty acid-binding protein 12 Fatty acid-binding protein 5 Fatty acid-binding protein 9 Fatty acid-binding protein, adipocyte Fatty acid-binding protein, brain Fatty acid-binding protein, heart Fatty acid-binding protein, intestinal Fatty acid-binding protein, liver Gastrotropin Glycerol-3-phosphate dehydrogenase, mitochondrial Hormone-sensitive lipase Monoglyceride lipase Patatin-like phospholipase domain-containing protein 4 Patatin-like phospholipase domain-containing protein 5 Perilipin-1 Perilipin-3 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	A6NFH5 O15540 O60240 O60664 P05413 P07148 P12104 P15090 P17612 P22612 P22694 P36873 P41247 P43304 P51161 P62136 P62140 Q01469 Q03135 Q05469 Q0Z7S8 Q7Z6Z6 Q8WTS1 Q99685	ABHD5 BLBP CAV CAV1 DXS1283E FABP1 FABP11 FABP12 FABP2 FABP3 FABP4 FABP5 FABP6 FABP7 FABP9 FABPB FABPI FABPL GPD2 GS2 GS2L ILBP ILLBP LIPE M6PRBP1 MDGI MGLL MRG NCIE2 PERI PKACA PLIN PLIN1 PLIN3 PNPLA4 PNPLA5 PPP1A PPP1CA PPP1CB PPP1CC PRKACA PRKACB PRKACG TIP47	Homo sapiens (human)
SARS-CoV-2 modulates host translation machinery	Gem-associated protein 2 Gem-associated protein 4 Gem-associated protein 5 Gem-associated protein 6 Gem-associated protein 7 Gem-associated protein 8 Probable ATP-dependent RNA helicase DDX20 Replicase polyprotein 1a Replicase polyprotein 1ab Ribosomal protein eS27-like Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Survival motor neuron protein Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14893 P08708 P08865 P0DTC1 P0DTD1 P14678 P15880 P22090 P23396 P25398 P39019 P42677 P46781 P46782 P46783 P57678 P60866 P61247 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62304 P62306 P62308 P62314 P62316 P62318 P62701 P62753 P62841 P62847 P62851 P62854 P62857 P62861 P62979 P63220 Q16637 Q71UM5 Q8TD47 Q8TEQ6 Q8WXD5 Q9H840 Q9NWZ8 Q9UHI6	CCG2 COD D6S218E DDX20 DP103 FAM51A1 FAU FTE1 GEMIN2 GEMIN3 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 LAMBR LAMR1 MFTL MPS1 PBSCF PBSCG RIG RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA SCAR SIP1 SMN SMN1 SMN2 SMNC SMNT SNRPB SNRPB1 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG UBA80 UBCEP1 rep	Homo sapiens (human)
Defective pro-SFTPB causes SMDP1 and RDS	Pulmonary surfactant-associated protein B	P07988	SFTP3 SFTPB	Homo sapiens (human)
RND3 GTPase cycle	Ankyrin repeat domain-containing protein 26 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Carboxypeptidase D Caveolin-1 Creatine kinase B-type Cytoskeleton-associated protein 4 DEP domain-containing protein 1B Desmoglein-1 Desmoplakin Disks large homolog 5 Dystonin Ephrin type-A receptor 2 Flotillin-2 Girdin Inner nuclear membrane protein Man1 Kinectin Mucin-13 Nischarin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-binding clathrin assembly protein Plakophilin-4 Pleckstrin homology domain-containing family G member 5 Probable ATP-dependent RNA helicase DDX4 Protein FAM83B Protein scribble homolog RNA-binding motif protein, X chromosome Ras GTPase-activating protein nGAP Rho GTPase-activating protein 21 Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Rho-associated protein kinase 1 Rho-related GTP-binding protein RhoE Semaphorin-4F Thioredoxin-like protein 1 Tropomodulin-3 Tyrosine-protein phosphatase non-receptor type 13 UBX domain-containing protein 11 Vang-like protein 1 Vang-like protein 2 tRNA (34-2'-O)-methyltransferase regulator WDR6	O00459 O43396 O75976 O94827 O95754 P12277 P15924 P27986 P29317 P38159 P61587 Q02413 Q03001 Q03135 Q07065 Q12923 Q13017 Q13464 Q13492 Q13829 Q14160 Q14254 Q3V6T2 Q5T0W9 Q5T124 Q5T5U3 Q86UP2 Q8TAA9 Q8TDM6 Q8WUY9 Q8WZ19 Q99569 Q9H3R2 Q9NNW5 Q9NQI0 Q9NRY4 Q9NYL9 Q9UJF2 Q9ULK5 Q9UPS8 Q9Y2I1 Q9Y2U8	ANKRD26 APE ARHE ARHGAP10 ARHGAP21 ARHGAP35 ARHGAP5 BACURD1 BACURD2 BP230 BP240 BPAG1 C6orf143 CALM CAV CAV1 CCDC88A CDHF4 CG1 CKAP4 CKB CKBB CPD CRIB1 DDX4 DEPDC1B DLG5 DMH DRCC1 DSG1 DSP DST DT ECK EDP1 EPHA2 ESA1 FAM83B FLOT2 GRB1 GRDN GRF1 GRLF1 HNRPG IRAS KCTD13 KIAA0004 KIAA0147 KIAA0583 KIAA0720 KIAA0728 KIAA0975 KIAA1074 KIAA1212 KIAA1215 KIAA1424 KIAA1722 KTN1 LAP4 LEMD3 M17S1 MAN1 MUC13 NGAP NISCH P190A PDIP1 PDLG PICALM PIK3R1 PIK3R2 PKP4 PLEKHG5 PNP1 POLDIP1 PTP1E PTPL1 PTPN13 RASAL2 RBMX RBMXP1 RECC RHO8 RHOE RHOGAP5 RND3 ROCK1 SCRB1 SCRIB SEMA4F SEMAM SEMAW SOC STB1 STB2 TMOD3 TNFAIP1 TRP32 TXL TXNL TXNL1 UBXD5 UBXN11 VANGL1 VANGL2 VARTUL VASA WDR6 XTP8 p190ARHOGAP	Homo sapiens (human)
Negative regulation of TCF-dependent signaling by WNT ligand antagonists	Dickkopf-related protein 1 Dickkopf-related protein 2 Dickkopf-related protein 4 Kremen protein 1 Kremen protein 2 Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Protein Wnt-3a Protein Wnt-4 Protein Wnt-5a Protein Wnt-9a Sclerostin Secreted frizzled-related protein 1 Secreted frizzled-related protein 2 Wnt inhibitory factor 1	O14904 O75197 O75581 O94907 P41221 P56704 P56705 Q8N474 Q8NCW0 Q96HF1 Q96MU8 Q9BQB4 Q9UBT3 Q9UBU2 Q9Y5W5	DKK1 DKK2 DKK4 FRP FRP1 FRP2 KREMEN KREMEN1 KREMEN2 KRM1 KRM2 LR3 LRP5 LRP6 LRP7 SARP1 SARP2 SFRP1 SFRP2 SOST WIF1 WNT14 WNT3A WNT4 WNT5A WNT9A	Homo sapiens (human)
Interleukin-37 signaling	Caspase-1 Interleukin-18 receptor 1 Interleukin-18-binding protein Interleukin-37 Mothers against decapentaplegic homolog 3 Serine/threonine-protein kinase TBK1 Signal transducer and activator of transcription 3 Single Ig IL-1-related receptor Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 12 Tyrosine-protein phosphatase non-receptor type 13 Tyrosine-protein phosphatase non-receptor type 14 Tyrosine-protein phosphatase non-receptor type 18 Tyrosine-protein phosphatase non-receptor type 20 Tyrosine-protein phosphatase non-receptor type 23 Tyrosine-protein phosphatase non-receptor type 2 Tyrosine-protein phosphatase non-receptor type 4 Tyrosine-protein phosphatase non-receptor type 5 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type 7 Tyrosine-protein phosphatase non-receptor type 9	O95998 P17706 P29074 P29350 P29466 P35236 P40763 P43378 P54829 P84022 Q05209 Q06124 Q12923 Q13478 Q15678 Q4JDL3 Q6IA17 Q99952 Q9H3S7 Q9NZH6 Q9UHD2	APRF BDP1 CASP1 FIL1Z HCP IL18BP IL18R1 IL1BC IL1BCE IL1F7 IL1H4 IL1RP1 IL1RRP IL37 KIAA1471 MADH3 NAK PEZ PNP1 PTP1C PTP1E PTP2C PTPD2 PTPL1 PTPN11 PTPN12 PTPN13 PTPN14 PTPN18 PTPN2 PTPN20 PTPN20A PTPN20B PTPN23 PTPN4 PTPN5 PTPN6 PTPN7 PTPN9 PTPT SHPTP2 SIGIRR SMAD3 STAT3 TBK1	Homo sapiens (human)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)	RWD domain-containing protein 3 SUMO-activating enzyme subunit 1 SUMO-activating enzyme subunit 2 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3	P55854 P61956 P63165 P63279 Q9UBE0 Q9UBT2 Q9Y3V2	AOS1 RSUME RWDD3 SAE1 SAE2 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUA1 SUMO1 SUMO2 SUMO3 UBA2 UBC9 UBCE9 UBE2I UBL1 UBLE1A UBLE1B	Homo sapiens (human)
Proton-coupled neutral amino acid transporters	Proton-coupled amino acid transporter 1 Proton-coupled amino acid transporter 2	Q495M3 Q7Z2H8	PAT1 PAT2 SLC36A1 SLC36A2 TRAMD1	Homo sapiens (human)
Defective B3GAT3 causes JDSSDHD	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Neurocan core protein Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Versican core protein	O00468 O14594 O75056 O75487 O94766 O95196 P07585 P13611 P18827 P21810 P31431 P34741 P35052 P51654 P78333 P98160 Q6UVK1 Q8N158 Q96GW7 Q9Y625	AGRIN AGRN B3GAT3 BCAN BEHAB BGN CALEB CSPG2 CSPG3 CSPG4 CSPG5 CSPG7 DCN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HSPG1 HSPG2 KIAA0468 MCSP NCAN NEUR NGC OCI5 SDC SDC1 SDC2 SDC3 SDC4 SLRR1A SLRR1B VCAN	Homo sapiens (human)
Costimulation by the CD28 family	B- and T-lymphocyte attenuator ICOS ligand Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tumor necrosis factor receptor superfamily member 14 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	O00459 O75144 P27986 P29350 P42336 Q06124 Q7Z6A9 Q92569 Q92956	B7H2 B7RP1 BTLA GRB1 HCP HVEA HVEM ICOSL ICOSLG KIAA0653 PIK3CA PIK3R1 PIK3R2 PIK3R3 PTP1C PTP2C PTPN11 PTPN6 SHPTP2 TNFRSF14	Homo sapiens (human)
lorlatinib-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK	Homo sapiens (human)
MET activates RAP1 and RAC1	Adapter molecule crk Crk-like protein Dedicator of cytokinesis protein 7 GRB2-associated-binding protein 1 Hepatocyte growth factor receptor Hepatocyte growth factor Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rap-1A Ras-related protein Rap-1b	P08581 P14210 P46108 P46109 P61224 P62834 P63000 Q13480 Q13905 Q96N67	CRK CRKL DOCK7 GAB1 GRF2 HGF HPTA KIAA1771 KREV1 MET RAC1 RAP1A RAP1B RAPGEF1 TC25	Homo sapiens (human)
Pre-NOTCH Transcription and Translation	CREB-binding protein Cellular tumor antigen p53 ETS-related transcription factor Elf-3 G1/S-specific cyclin-D1 Helicase MOV-10 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 NAD-dependent protein deacylase sirtuin-6 Neurogenic locus notch homolog protein 1 Neurogenic locus notch homolog protein 2 Neurogenic locus notch homolog protein 3 Neurogenic locus notch homolog protein 4 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Protein kinase C iota type Recombining binding protein suppressor of hairless Runt-related transcription factor 1 SNW domain-containing protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F3 Transcription factor Jun Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	O00716 O60814 P04637 P04908 P05412 P06899 P0C5Y9 P16104 P20671 P23527 P24385 P33778 P41743 P46531 P57053 P58876 P62805 P62807 P68431 P78545 P84243 Q01094 Q01196 Q04721 Q06330 Q09472 Q13495 Q13573 Q14186 Q14188 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8IZL2 Q8N257 Q8N6T7 Q8NDV7 Q92585 Q92793 Q92830 Q92831 Q93077 Q93079 Q96A08 Q96JK9 Q99466 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UM47 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 AML1 BCL1 CAGH26 CBFA2 CBP CCND1 CG1 CREBBP CXorf6 DP1 DP2 DXS1179E E2F1 E2F3 EIF2C1 EIF2C2 EIF2C3 EIF2C4 ELF3 EP300 ERT ESX GCN5 GCN5L2 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 IGKJRB IGKJRB1 INT3 JEN JUN KAT2A KAT2B KIAA0075 KIAA0200 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KIAA1816 KIAA1819 MAML1 MAML2 MAML3 MAMLD1 MOV10 NOTCH1 NOTCH2 NOTCH3 NOTCH4 P300 P53 PCAF PRAD1 PRKCI RBBP3 RBPJ RBPJK RBPSUH RUNX1 SIR2L6 SIRT6 SKIIP SKIP SNW1 TAN1 TFDP1 TFDP2 TNRC6 TNRC6A TNRC6B TNRC6C TP53 TSH2B	Homo sapiens (human)
FCERI mediated MAPK activation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 GRB2-related adapter protein 2 GTPase HRas GTPase NRas Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Lymphocyte cytosolic protein 2 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Mitogen-activated protein kinase kinase kinase 1 Protein c-Fos Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Son of sevenless homolog 1 Transcription factor Jun Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O14733 O75791 P01100 P01111 P01112 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P05412 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P15498 P16885 P19174 P23083 P27361 P28482 P43405 P45983 P45984 P45985 P52735 P53779 P63000 P80748 Q07889 Q13094 Q13153 Q13177 Q13233 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9UKW4	ERK1 ERK2 FOS G0S7 GADS GRAP2 GRB2L GRID HRAS HRAS1 IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 JNK1 JNK2 JNK3 JNK3A JNKK1 JNKK2 JTK8 JUN LCP2 LYN MAP2K4 MAP2K7 MAP3K1 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MAPKKK1 MEK4 MEK7 MEKK MEKK1 MKK4 MKK7 NRAS PAK1 PAK2 PLC1 PLCG1 PLCG2 PRKM1 PRKM10 PRKM2 PRKM3 PRKM8 PRKM9 PRKMK4 PRKMK7 RAC1 SAPK1 SAPK1A SAPK1B SAPK1C SEK1 SERK1 SKK1 SKK4 SOS1 SYK TC25 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3	Homo sapiens (human)
Interleukin-10 signaling	C-C chemokine receptor type 1 C-C chemokine receptor type 2 C-C chemokine receptor type 5 C-C motif chemokine 19 C-C motif chemokine 20 C-C motif chemokine 22 C-C motif chemokine 2 C-C motif chemokine 3-like 1 C-C motif chemokine 3 C-C motif chemokine 4 C-C motif chemokine 5 C-X-C motif chemokine 10 C-X-C motif chemokine 2 Granulocyte colony-stimulating factor Granulocyte-macrophage colony-stimulating factor Growth-regulated alpha protein Intercellular adhesion molecule 1 Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor antagonist protein Interleukin-1 receptor type 1 Interleukin-1 receptor type 2 Interleukin-10 receptor subunit alpha Interleukin-10 receptor subunit beta Interleukin-10 Interleukin-12 subunit alpha Interleukin-12 subunit beta Interleukin-18 Interleukin-6 Interleukin-8 Leukemia inhibitory factor Low affinity immunoglobulin epsilon Fc receptor Macrophage colony-stimulating factor 1 Metalloproteinase inhibitor 1 Non-receptor tyrosine-protein kinase TYK2 Platelet-activating factor receptor Prostaglandin G/H synthase 2 Signal transducer and activator of transcription 3 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor Tyrosine-protein kinase JAK1 fMet-Leu-Phe receptor	O00626 P01033 P01375 P01583 P01584 P02778 P04141 P05231 P05362 P06734 P09341 P09603 P09919 P10145 P10147 P13236 P13500 P13501 P14778 P15018 P16619 P18510 P19438 P19875 P20333 P21462 P22301 P23458 P25105 P27930 P29459 P29460 P29597 P32246 P33681 P35354 P40763 P41597 P42081 P51681 P78556 Q08334 Q13651 Q14116 Q99731	APRF C17orf33 CCL19 CCL2 CCL20 CCL22 CCL3 CCL3L1 CCL3L3 CCL4 CCL5 CCR1 CCR2 CCR5 CD23A CD28LG CD28LG1 CD28LG2 CD80 CD86 CLEC4J CLGI CMKBR1 CMKBR2 CMKBR5 CMKR1 COX2 CRFB4 CSF1 CSF2 CSF3 CXCL1 CXCL10 CXCL2 CXCL8 D17S136E D17S1718 D21S58 D21S66 ELC FCE2 FCER2 FPR1 G0S19-1 G0S19-2 GCSF GMCSF GRO GRO1 GRO2 GROA GROB HILDA ICAM1 IFNB2 IGEBF IGIF IL10 IL10R IL10RA IL10RB IL12A IL12B IL18 IL1A IL1B IL1F1 IL1F2 IL1F3 IL1F4 IL1R IL1R1 IL1R2 IL1RA IL1RB IL1RN IL1RT1 IL6 IL8 INP10 JAK1 JAK1A JAK1B LAB7 LAG1 LARC LIF MCP1 MDC MGSA MIP1A MIP1B MIP2A MIP3A MIP3B NKSF1 NKSF2 PAFR PTAFR PTGS2 SCYA19 SCYA2 SCYA20 SCYA22 SCYA3 SCYA3L1 SCYA4 SCYA5 SCYAR1 SCYB1 SCYB10 SCYB2 STAT3 TIMP TIMP1 TNF TNFA TNFAR TNFBR TNFR1 TNFR2 TNFRSF1A TNFRSF1B TNFSF2 TYK2	Homo sapiens (human)
Phase 2 - plateau phase	A-kinase anchor protein 9 Potassium voltage-gated channel subfamily E member 1 Potassium voltage-gated channel subfamily E member 2 Potassium voltage-gated channel subfamily E member 3 Potassium voltage-gated channel subfamily E member 4 Potassium voltage-gated channel subfamily E regulatory beta subunit 5 Potassium voltage-gated channel subfamily KQT member 1 Voltage-dependent L-type calcium channel subunit alpha-1C Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-6 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit Voltage-dependent calcium channel subunit alpha-2/delta-2	P15382 P51787 P62955 Q02641 Q08289 Q13936 Q8WWG9 Q8WXS5 Q99996 Q9BXT2 Q9NY47 Q9UBN1 Q9UJ90 Q9Y6H6 Q9Y6J6	AKAP350 AKAP450 AKAP9 AMMECR2 CACH2 CACN2 CACNA1C CACNA2D2 CACNB1 CACNB2 CACNG4 CACNG6 CACNG7 CACNG8 CACNL1A1 CACNLB1 CACNLB2 CCHL1A1 KCNA8 KCNA9 KCNE1 KCNE1L KCNE2 KCNE3 KCNE4 KCNE5 KCNQ1 KIAA0558 KIAA0803 KVLQT1 MYSB	Homo sapiens (human)
TYSND1 cleaves peroxisomal proteins	3-ketoacyl-CoA thiolase, peroxisomal Alkyldihydroxyacetonephosphate synthase, peroxisomal Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal leader peptide-processing protease Peroxisomal multifunctional enzyme type 2 Phytanoyl-CoA dioxygenase, peroxisomal Sterol carrier protein 2	O00116 O14832 P09110 P22307 P51659 Q15067 Q2T9J0	ACAA ACAA1 ACOX ACOX1 AGPS EDH17B4 HSD17B4 PAHX PHYH PTHIO SCP2 SDR8C1 TYSND1	Homo sapiens (human)
NOD1/2 Signaling Pathway	Angio-associated migratory cell protein Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase recruitment domain-containing protein 9 Caspase-1 Caspase-2 Caspase-4 Caspase-8 Caspase-9 Dual specificity mitogen-activated protein kinase kinase 6 E3 ubiquitin-protein ligase Itchy homolog Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Nucleoprotein Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Tumor necrosis factor alpha-induced protein 3 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 O15264 O43187 O43318 O43353 P0DTC9 P21580 P29466 P42575 P49662 P51617 P52564 P53778 P55211 P61088 Q13404 Q13489 Q13490 Q13685 Q14790 Q15750 Q15759 Q16539 Q8N5C8 Q96J02 Q9H257 Q9HC29 Q9NQC7 Q9NYJ8 Q9Y239 Q9Y4K3 Q9Y6K9	AAMP API1 API2 BIRC2 BIRC3 BLU CARD15 CARD4 CARD9 CARDIAK CASP1 CASP2 CASP4 CASP8 CASP9 CHUK CROC1 CSBP CSBP1 CSBP2 CSPB1 CYLD CYLD1 ERK6 FIP3 ICH1 ICH2 IKBKB IKBKG IKKA IKKB IL1BC IL1BCE IRAK IRAK1 IRAK2 ITCH KIAA0733 KIAA0849 MAP2K6 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPK11 MAPK12 MAPK13 MAPK14 MCH5 MCH6 MEK6 MIHB MIHC MKK6 MXI2 N NEDD2 NEMO NOD1 NOD2 OTUD7C PRKM11 PRKM13 PRKMK6 RICK RIP2 RIPK2 RNF48 RNF49 RNF85 SAPK2 SAPK2A SAPK2B SAPK3 SAPK4 SKK3 TAB1 TAB2 TAB3 TAK1 TCF16 TNFAIP3 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)

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