GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
ADORA2B mediated anti-inflammatory cytokines production	Adenosine receptor A2b Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Interleukin-6 cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A8MTJ3 O14610 O14775 O43306 O60262 O60266 O60503 O95622 P04899 P05231 P08754 P10644 P13861 P16520 P17612 P19086 P22612 P22694 P29275 P31321 P31323 P40145 P50150 P50151 P51817 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADORA2B GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP IFNB2 IL6 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PKX1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX TSE1	Homo sapiens (human)
SUMOylation of chromatin organization proteins	Aladin Chromobox protein homolog 2 Chromobox protein homolog 5 Chromobox protein homolog 8 Chromodomain-helicase-DNA-binding protein 3 DNA-binding protein SATB1 DNA-binding protein SATB2 E3 SUMO-protein ligase CBX4 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase RanBP2 E3 SUMO-protein ligase ZBED1 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Histone H4 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 4 Lethal(3)malignant brain tumor-like protein 2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Protein SEC13 homolog SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 mRNA export factor RAE1	A8CG34 O00257 O15504 O75694 O75925 O96006 P12270 P35226 P35227 P35658 P37198 P45973 P49790 P49792 P55735 P55854 P56524 P57740 P61956 P62805 P63165 P63279 P78364 P78406 Q01826 Q06587 Q12769 Q12873 Q13547 Q14781 Q15022 Q5SRE5 Q7Z3B4 Q8IXK0 Q8N1F7 Q8NDX5 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q92769 Q969R5 Q96HA1 Q99496 Q99567 Q9BTX1 Q9BW27 Q9HC52 Q9NRG9 Q9UKX7 Q9UPW6	AAAS ADRACALA ALTE BAP1 BMI1 C7orf14 CAIN CAN CBX2 CBX4 CBX5 CBX8 CG1 CHD3 CHET9 D3S1231E DDXBP1 DING DREF EDR1 EDR2 EDR3 H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HDAC1 HDAC2 HDAC4 HIPI3 HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H4 HIST2H4A HIST2H4B HIST4H4 HP1A JJAZ1 KIAA0023 KIAA0095 KIAA0160 KIAA0169 KIAA0197 KIAA0225 KIAA0288 KIAA0618 KIAA0785 KIAA0791 KIAA0906 KIAA1034 L3MBTL2 MEL18 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PC3 PCGF2 PCGF4 PCNT1 PH1 PH2 PH3 PHC1 PHC2 PHC3 PIAS1 POM121 POM121A POM121C RAE1 RANBP2 RC1 RING1 RING1A RING1B RNF1 RNF110 RNF2 RNF51 RPD3L1 SATB1 SATB2 SEC13 SEC13A SEC13L1 SEC13R SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUMO1 SUMO2 SUMO3 SUZ12 TMEM48 TPR TRAMP UBC9 UBCE9 UBE2I UBL1 ZBED1 ZNF144 hDREF	Homo sapiens (human)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	26S proteasome complex subunit SEM1 BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA repair protein RAD51 homolog 2 DNA repair protein RAD51 homolog 3 DNA repair protein RAD51 homolog 4 DNA repair protein XRCC2 DNA repair protein XRCC3 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin Partner and localizer of BRCA2 RAD51-associated protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Regulator of telomere elongation helicase 1 Serine-protein kinase ATM	O15315 O43502 O43542 O43543 O60934 O75771 P38398 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q14191 Q86YC2 Q92878 Q92993 Q96B01 Q96E14 Q99708 Q99728 Q9BX63 Q9H9A7 Q9NZ71 Q9UQ84	ATM BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C16orf75 C20orf41 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FANCN HEX1 HNGS1 HTATIP KAT5 KIAA0083 KIAA1088 MRE11 MRE11A NBN NBS NBS1 NHL P95 PALB2 PIR51 RAD50 RAD51 RAD51A RAD51AP1 RAD51B RAD51C RAD51D RAD51L1 RAD51L2 RAD51L3 RBBP8 REC2 RECA RECQ2 RECQ3 RECQL2 RECQL3 RMI1 RMI2 RNF53 RTEL1 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A WRN XRCC2 XRCC3	Homo sapiens (human)
PI Metabolism	Tumor necrosis factor alpha-induced protein 8-like protein 1 Tumor necrosis factor alpha-induced protein 8-like protein 2 Tumor necrosis factor alpha-induced protein 8-like protein 3 Tumor necrosis factor alpha-induced protein 8	O95379 Q5GJ75 Q6P589 Q8WVP5	TIPE3 TNFAIP8 TNFAIP8L1 TNFAIP8L2 TNFAIP8L3	Homo sapiens (human)
Respiratory syncytial virus (RSV) attachment and entry	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein CX3C chemokine receptor 1 Epidermal growth factor receptor Furin Fusion glycoprotein F0 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Insulin-like growth factor 1 receptor Lymphocyte antigen 96 Matrix protein Monocyte differentiation antigen CD14 Nucleolin Nucleoprotein Phosphoprotein Protein M2-1 RNA-directed RNA polymerase L Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Toll-like receptor 4	O00206 O00468 O75056 O75487 P00533 P03418 P03420 P03421 P04545 P08069 P08571 P09958 P0DOE7 P18827 P19338 P20339 P28887 P31431 P34741 P35052 P49238 P51148 P51654 P61020 P78333 P98160 Q8N158 Q9Y625 Q9Y6Y9	AGRIN AGRN CD14 CMKBRL1 CX3CR1 EGFR ERBB ERBB1 ESOP1 F FUR FURIN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 GPR13 HER1 HSPG1 HSPG2 IGF1R KIAA0468 L LY96 M M2-1 MD2 N NCL OCI5 P PACE PCSK3 RAB5 RAB5A RAB5B RAB5C RABL SDC SDC1 SDC2 SDC3 SDC4 TLR4	Homo sapiens (human)
Phase I - Functionalization of compounds	Aldehyde dehydrogenase, dimeric NADP-preferring Amine oxidase [copper-containing] 2 Amine oxidase [copper-containing] 3 Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Carbonyl reductase [NADPH] 3 Carboxylesterase 3 Carboxymethylenebutenolidase homolog Cocaine esterase Cytochrome P450 2B6 Cytochrome P450 3A4 Cytochrome b5 type B Diamine oxidase [copper-containing] Epoxide hydrolase 1 Liver carboxylesterase 1 Mitochondrial amidoxime reducing component 2 Mitochondrial amidoxime-reducing component 1 NADH-cytochrome b5 reductase 3 Ribosyldihydronicotinamide dehydrogenase [quinone] Valacyclovir hydrolase	A9YTQ3 O00748 O43169 O75106 O75828 P00387 P07099 P08684 P16083 P19801 P20813 P22760 P23141 P27540 P30838 P35869 Q16853 Q5VT66 Q6UWW8 Q86WA6 Q969Z3 Q96DG6 Q9HBZ2	AADAC ABP ABP1 AHR AHRR ALDH3 ALDH3A1 AOC1 AOC2 AOC3 ARNT ARNT2 BHLHE1 BHLHE2 BHLHE76 BHLHE77 BPHL CBR3 CES1 CES2 CES3 CMBL CYB5B CYB5M CYB5R3 CYP2B6 CYP3A3 CYP3A4 DAC DAO DIA1 EPHX EPHX1 EPOX ICE KIAA0307 KIAA1234 MARC1 MARC2 MCNAA MOSC1 MOSC2 MTARC1 MTARC2 NMOR2 NQO2 OMB5 SDR21C2 SES1 VAP1	Homo sapiens (human)
ASP-3026-resistant ALK mutants	ALK tyrosine kinase receptor	Q9UM73	ALK	Homo sapiens (human)
Regulation of necroptotic cell death	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase-8 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase XIAP E3 ubiquitin-protein ligase parkin E3 ubiquitin-protein ligase pellino homolog 1 FAS-associated death domain protein Flotillin-1 Flotillin-2 Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Mixed lineage kinase domain-like protein Polyubiquitin-B Polyubiquitin-C Programmed cell death 6-interacting protein Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 Syntenin-1 TNF receptor-associated factor 2 Tumor necrosis factor receptor type 1-associated DEATH domain protein UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit Ubiquitin-conjugating enzyme E2 L3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00560 O15294 O60260 O75955 P07900 P0CG47 P0CG48 P62979 P62987 P68036 P98170 Q12933 Q13158 Q13489 Q13490 Q13546 Q14254 Q14790 Q15628 Q16543 Q8NB16 Q8WUM4 Q96FA3 Q96J02 Q9UNE7 Q9Y572	AIP1 ALIX API1 API2 API3 BIRC2 BIRC3 BIRC4 CASP8 CDC37 CDC37A CHIP ESA1 FADD FLOT1 FLOT2 HSP90A HSP90AA1 HSPC1 HSPCA IAP3 ITCH KIAA1375 M17S1 MCH5 MDA9 MIHB MIHC MLKL MORT1 OGT PARK2 PDCD6IP PELI1 PRISM PRKN RIP RIP1 RIP3 RIPK1 RIPK3 RNF48 RNF49 RPS27A SDCBP STUB1 SYCL TRADD TRAF2 TRAP3 UBA52 UBA80 UBB UBC UBCE7 UBCEP1 UBCEP2 UBCH7 UBE2L3 XIAP	Homo sapiens (human)
Interleukin-21 signaling	Cytokine receptor common subunit gamma Interleukin-21 receptor Interleukin-21 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK3	P23458 P31785 P40763 P42224 P42229 P51692 P52333 Q14765 Q9HBE4 Q9HBE5	APRF IL21 IL21R IL2RG JAK1 JAK1A JAK1B JAK3 NILR STAT1 STAT3 STAT4 STAT5 STAT5A STAT5B	Homo sapiens (human)
LXRs regulate gene expression linked to gluconeogenesis	Nuclear receptor-interacting protein 1 Oxysterols receptor LXR-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta	P19793 P28702 P35558 P48552 Q13133	LXRA NR1H3 NR2B1 NR2B2 NRIP1 PCK1 PEPCK1 RXRA RXRB	Homo sapiens (human)
Signaling by RAS GTPase mutants	GTPase HRas GTPase KRas GTPase NRas	P01111 P01112 P01116	HRAS HRAS1 KRAS KRAS2 NRAS RASK2	Homo sapiens (human)
Beta oxidation of myristoyl-CoA to lauroyl-CoA	Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P28330 P40939 P55084	ACADL HADH HADHA HADHB	Homo sapiens (human)
Neurotransmitter release cycle	N-acylethanolamine-hydrolyzing acid amidase	Q02083	ASAHL NAAA PLT	Homo sapiens (human)
EPHA-mediated growth cone collapse	Ephexin-1 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O14950 O75116 P06241 P07947 P07948 P24844 P35579 P35580 P35749 P60660 P61586 Q13464 Q7Z406 Q8N5V2	ARH12 ARHA FYN JTK8 KIAA0619 KIAA0866 KIAA2034 LYN MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYRL2 NGEF RHO12 RHOA ROCK1 ROCK2 YES YES1	Homo sapiens (human)
SLC15A4:TASL-dependent IRF5 activation	Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon regulatory factor 5 NF-kappa-B essential modulator Solute carrier family 15 member 4 TLR adapter interacting with SLC15A4 on the lysosome	O14920 O15111 Q13568 Q8N697 Q9HAI6 Q9Y6K9	CHUK CXorf21 FIP3 IKBKB IKBKG IKKA IKKB IRF5 NEMO PHT1 PTR4 SLC15A4 TASL TCF16	Homo sapiens (human)
Heme signaling	3'-5' exoribonuclease HELZ2 Apolipoprotein A-I Apolipoprotein B-100 Basic helix-loop-helix ARNT-like protein 1 C-type lectin domain family 1 member B CREB-binding protein CREB-regulated transcription coactivator 1 CREB-regulated transcription coactivator 2 CREB-regulated transcription coactivator 3 Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Cyclic AMP-dependent transcription factor ATF-2 Exportin-1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Heme oxygenase 1 Hemoglobin subunit alpha Hemoglobin subunit beta Histone acetyltransferase p300 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Lymphocyte antigen 96 Mediator of RNA polymerase II transcription subunit 1 Membrane-associated progesterone receptor component 2 Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D NAD-dependent protein deacetylase sirtuin-1 Neuronal PAS domain-containing protein 2 Nuclear factor erythroid 2-related factor 2 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor-interacting protein 1 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Proton-coupled folate transporter Retinoic acid receptor RXR-alpha Retinoic acid-induced protein 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Toll-like receptor 4 Transcription factor MafK Transcription regulator protein BACH1 Trimethylguanosine synthase	O00206 O00327 O14867 O14980 O15173 O15379 O15516 O60675 O60907 O75376 P02647 P04114 P09601 P15336 P19793 P20393 P35398 P48552 P68871 P69905 Q06413 Q07869 Q09472 Q14686 Q14814 Q15596 Q15648 Q15788 Q16236 Q3L8U1 Q53ET0 Q6STE5 Q6UUV7 Q6UUV9 Q7Z5J4 Q86X55 Q92793 Q96EB6 Q96NT5 Q96RS0 Q99743 Q9BYK8 Q9BZK7 Q9P126 Q9UBK2 Q9Y6Y9	AIB3 APOA1 APOB ARC205 ARNTL ATF2 BACH1 BAF60C BHLHE5 BHLHE74 BHLHE75 BHLHE8 BHLHE9 BMAL1 CARM1 CBP CHD9 CLEC1B CLEC2 CLOCK CREB2 CREBBP CREBP1 CRM1 CRSP1 CRSP200 CRTC1 CRTC2 CRTC3 DG6 DRIP205 DRIP230 EAR1 EP300 ESOP1 G21 HBA1 HBA2 HBB HCA137 HCP1 HDAC3 HELZ2 HMOX1 HO HO1 HREV IRA1 KIAA0181 KIAA0308 KIAA0334 KIAA0616 KIAA1047 KIAA1769 KIAA1820 KISH2 LEM6 LY96 MAFK MD2 MECT1 MED1 MEF2C MEF2D MOP3 MOP4 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NFE2L2 NPAS2 NR1C1 NR1D1 NR1F1 NR2B1 NRF2 NRIP1 P300 PASD3 PASD4 PBP PCFT PGC1 PGC1A PGRMC2 PIMT PMBP PPAR PPARA PPARBP PPARGBP PPARGC1 PPARGC1A PRIC285 PRIC320 PRMT4 RAI1 RAP250 RB18A RORA RXRA RZRA SIR2L1 SIRT1 SLC46A1 SMARCD3 SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 THRAL TIF2 TLR4 TORC1 TORC2 TORC3 TRAP220 TRBP TRIP2 WAMTP1 XPO1	Homo sapiens (human)
Glyoxylate metabolism and glycine degradation	2-Hydroxyacid oxidase 1 4-hydroxy-2-oxoglutarate aldolase, mitochondrial Alanine--glyoxylate aminotransferase 2, mitochondrial Alanine--glyoxylate aminotransferase Aspartate aminotransferase, mitochondrial D-amino-acid oxidase D-aspartate oxidase Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial Glycine N-methyltransferase Glyoxylate reductase/hydroxypyruvate reductase Hydroxyproline dehydrogenase Peroxisomal membrane protein 2	P00505 P14920 P21549 P30038 Q14749 Q86XE5 Q99489 Q9BYV1 Q9NR77 Q9UBQ7 Q9UF12 Q9UJM8	AGT1 AGT2 AGXT AGXT2 ALDH4 ALDH4A1 C10orf65 DAMOX DAO DDO DHDPSL GLXR GNMT GOT2 GOX1 GRHPR HAO1 HOGA1 HSPOX1 HYPDH KYAT4 P5CDH PMP22 PRODH2 PXMP2 SPAT	Homo sapiens (human)
Signaling by FGFR4 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1	P01111 P01112 P19174 P22455 P27986 P42336 Q07889 Q13480 Q8WU20	FGFR4 FRS2 GAB1 GRB1 HRAS HRAS1 JTK2 NRAS PIK3CA PIK3R1 PLC1 PLCG1 SOS1 TKF	Homo sapiens (human)
Aryl hydrocarbon receptor signalling	AH receptor-interacting protein Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Heat shock protein HSP 90-beta Prostaglandin E synthase 3	A9YTQ3 O00170 P08238 P27540 P35869 Q15185 Q9HBZ2	AHR AHRR AIP ARNT ARNT2 BHLHE1 BHLHE2 BHLHE76 BHLHE77 HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KIAA0307 KIAA1234 P23 PTGES3 TEBP XAP2	Homo sapiens (human)
Kandutsch-Russell pathway	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 7-dehydrocholesterol reductase Delta(24)-sterol reductase Lathosterol oxidase	O75845 Q15125 Q15392 Q9UBM7	D7SR DHCR24 DHCR7 EBP KIAA0018 SC5D SC5DL	Homo sapiens (human)
Replication of the SARS-CoV-2 genome	Probable ATP-dependent RNA helicase DDX5 Replicase polyprotein 1a Replicase polyprotein 1ab Retinoblastoma-associated protein Zinc finger CCHC-type and RNA-binding motif-containing protein 1 von Hippel-Lindau disease tumor suppressor	P06400 P0DTC1 P0DTD1 P17844 P40337 Q8TBF4	DDX5 G17P1 HELR HLR1 RB1 VHL ZCRB1 rep	Homo sapiens (human)
Eukaryotic Translation Termination	Acylamino-acid-releasing enzyme Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Eukaryotic peptide chain release factor GTP-binding subunit ERF3B Eukaryotic peptide chain release factor subunit 1 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Methyltransferase N6AMT1 Multifunctional methyltransferase subunit TRM112-like protein Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P05386 P05387 P05388 P08708 P08865 P13798 P15170 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P39019 P39023 P40429 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P50914 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62495 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q6P5R6 Q71UM5 Q8IYD1 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q9UI30 Q9UNX3 Q9Y3U8 Q9Y5N5	APEH BBC1 C21orf127 CCG2 D11S2243E D3F15S2 D3S48E D6S218E DNF15S2 DXS648E EC45 ERF1 ERF3A ERF3B ETF1 FAU FTE1 GSPT1 GSPT2 HEMK2 KMT9 LAMBR LAMR1 MFTL MPS1 N6AMT1 NEDD6 PRED28 QM RF1 RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SUP45L1 SURF-3 SURF3 TRMT112 TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
The retinoid cycle in cones (daylight vision)	Acyl-CoA wax alcohol acyltransferase 2 Long-wave-sensitive opsin 1 Medium-wave-sensitive opsin 1 Retinaldehyde-binding protein 1 Retinol-binding protein 3 Short-chain dehydrogenase/reductase 3 Short-wave-sensitive opsin 1	O75911 P03999 P04000 P04001 P10745 P12271 Q6E213	AWAT2 BCP CRALBP DC4 DGAT2L4 DHRS3 GCP MFAT OPN1LW OPN1MW OPN1SW RBP3 RCP RDH17 RLBP1 SDR16C1 WS	Homo sapiens (human)
Surfactant metabolism	Adenosine deaminase 2 Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Cytokine receptor common subunit beta Cytoskeleton-associated protein 4 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha LIM and cysteine-rich domains protein 1 Napsin-A P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Pepsin A-3 Pepsin A-4 Pepsin A-5 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Scavenger receptor cysteine-rich domain-containing protein DMBT1 Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Surfactant-associated protein 3 Thyroid transcription factor 1-associated protein 26 Transcription factor GATA-6 Transcription termination factor 1	O95436 O96009 P07988 P08913 P09668 P0C7M3 P0DJD7 P0DJD8 P0DJD9 P11686 P15509 P18825 P29274 P29275 P32927 P35247 P41231 Q06495 Q07065 Q15361 Q8IWL1 Q8IWL2 Q8IZF2 Q92908 Q99758 Q9NZK5 Q9NZU5 Q9P031 Q9UGM3 Q9UIJ5	ABC3 ABCA3 ADA2 ADGF ADGRF5 ADORA2 ADORA2A ADORA2B ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR BR22 CCDC59 CECR1 CKAP4 COLEC4 COLEC5 COLEC7 CPSB CSF2R CSF2RA CSF2RB CSF2RY CTSH DMBT1 GATA6 GP340 GPR116 IDGFL IL3RB IL5RB KIAA0758 LMCD1 NAP1 NAPA NAPSA NPT2 P2RU1 P2RY2 PGA3 PGA4 PGA5 PSAP PSPD REAM REC SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH SLC17A2 SLC34A1 SLC34A2 TAP26 TTF1 ZDHHC2 ZNF372	Homo sapiens (human)
Pyroptosis	Apoptosis regulator BAX Bcl-2 homologous antagonist/killer Caspase-1 Caspase-3 Caspase-4 Caspase-5 Cellular tumor antigen p53 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c Gasdermin-D Gasdermin-E Granzyme B High mobility group protein B1 Interferon regulatory factor 1 Interferon regulatory factor 2 Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Neutrophil elastase Tumor protein 63	O43633 O60443 P01583 P01584 P04637 P08246 P09429 P10144 P10914 P14316 P29466 P42574 P49662 P51878 P57764 P99999 Q07812 Q14116 Q16611 Q8WUX9 Q96CF2 Q96FZ7 Q9BY43 Q9H3D4 Q9H444 Q9UQN3 Q9Y3E7	BAK BAK1 BAX BC2 BCL2L4 BCL2L7 C14orf123 C20orf178 CASP1 CASP3 CASP4 CASP5 CDN1 CGI149 CGL1 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CPP32 CSPB CTLA1 CYC CYCS DFNA5 DFNA5L ELA2 ELANE GRB GSDMD GSDMDC1 GSDME GZMB HMG1 HMGB1 ICERE1 ICH2 ICH3 IGIF IL18 IL1A IL1B IL1BC IL1BCE IL1F1 IL1F2 IL1F4 IRF1 IRF2 KET NEDF P53 P63 P73H P73L SHAX1 SHAX2 SHAX3 TP53 TP63 TP73L VPS20 VPS24	Homo sapiens (human)

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