GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1251 - 1275** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
FCERI mediated Ca+2 mobilization	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Calcineurin subunit B type 1 Calmodulin-1 GRB2-related adapter protein 2 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Lymphocyte cytosolic protein 2 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 2 Nuclear factor of activated T-cells, cytoplasmic 3 Protein phosphatase 3 catalytic subunit alpha Proto-oncogene vav S-adenosylhomocysteine hydrolase-like protein 1 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform Son of sevenless homolog 1 Tyrosine-protein kinase BTK Tyrosine-protein kinase ITK/TSK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase TXK Tyrosine-protein kinase Tec UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O43865 O75791 O95644 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P0DP23 P15498 P16298 P16885 P19174 P23083 P42680 P42681 P43405 P52735 P63098 P80748 Q06187 Q07889 Q08209 Q08881 Q12968 Q13094 Q13469 Q14571 Q14573 Q14643 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9UKW4	AGMX1 AHCYL1 ATK BPK BTK CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CNA CNA2 CNB DCAL EMT GADS GRAP2 GRB2L GRID IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 INSP3R1 IRBIT ITK ITPR1 ITPR2 ITPR3 JTK8 LCP2 LYK LYN NFAT1 NFAT2 NFAT4 NFATC NFATC1 NFATC2 NFATC3 NFATP PLC1 PLCG1 PLCG2 PPP3CA PPP3CB PPP3R1 PSCTK4 PTK4 RLK SOS1 SYK TEC TXK V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3 XPVKONA	Homo sapiens (human)
Elastic fibre formation	Elastin Fibrillin-1 Fibrillin-2 Fibrillin-3 Fibulin-5 Furin Integrin alpha-5 Integrin alpha-V Integrin beta-1 Integrin beta-3 Integrin beta-6 Lysyl oxidase homolog 1 Lysyl oxidase homolog 2 Lysyl oxidase homolog 3 Lysyl oxidase homolog 4 Microfibrillar-associated protein 2 Microfibrillar-associated protein 5 Protein-lysine 6-oxidase	P05106 P05556 P06756 P08648 P09958 P15502 P18564 P28300 P35555 P35556 P55001 P58215 Q08397 Q13361 Q75N90 Q96JB6 Q9UBX5 Q9Y4K0	DANCE ELN FBLN5 FBN FBN1 FBN2 FBN3 FNRA FNRB FUR FURIN GP3A ITGA5 ITGAV ITGB1 ITGB3 ITGB6 KIAA1776 LOX LOXC LOXL LOXL1 LOXL2 LOXL3 LOXL4 MAGP1 MAGP2 MDF2 MFAP2 MFAP5 MSK12 MSK8 PACE PCSK3 VNRA VTNR	Homo sapiens (human)
Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1)	Sodium/iodide cotransporter	Q92911	NIS SLC5A5	Homo sapiens (human)
TWIK-related spinal cord K+ channel (TRESK)	Potassium channel subfamily K member 18	Q7Z418	KCNK18 TRESK TRIK	Homo sapiens (human)
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	CREB-binding protein Cullin-1 Cyclin-C Cyclin-dependent kinase 8 Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B E3 ubiquitin-protein ligase RBX1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Hairy/enhancer-of-split related with YRPW motif-like protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Myc proto-oncogene protein Neurogenic locus notch homolog protein 1 Nicastrin Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Protein jagged-1 Protein jagged-2 Recombining binding protein suppressor of hairless S-phase kinase-associated protein 1 SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O15379 O60907 O75376 O76050 P01106 P0CG47 P0CG48 P24863 P46531 P49336 P49768 P49810 P56524 P62877 P62979 P62987 P63208 P78504 P78536 Q06330 Q09472 Q13495 Q13547 Q13573 Q13616 Q14469 Q5TA89 Q86YT6 Q8IZL2 Q8WUI4 Q8WW43 Q92542 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96AX9 Q96BI3 Q96DB2 Q96JK9 Q9BY41 Q9BZK7 Q9NQ87 Q9NR61 Q9NZ42 Q9UBN7 Q9UBP5 Q9UKV0 Q9UQL6 Q9Y219 Q9Y5J3 Q9Y618	AD3 AD4 ADAM10 ADAM17 APH1A APH1B BHLHB31 BHLHB32 BHLHB33 BHLHB38 BHLHB39 BHLHE39 CBP CCNC CDK8 CG1 CHF1 CHF2 CREBBP CSVP CTG26 CUL1 CXorf6 DIP1 DLL1 DLL4 EMC19 EP300 GCN5 GCN5L2 GRL HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HEYL HL HRT1 HRT2 HRT3 HRY IGKJRB IGKJRB1 IRA1 JAG1 JAG2 JAGL1 KAT2A KAT2B KIAA0200 KIAA0253 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1323 KIAA1816 KIAA1819 KUZ MADM MAML1 MAML2 MAML3 MAMLD1 MIB1 MIB2 MITR MYC NCOR1 NCOR2 NCSTN NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH1 OCP2 P300 PCAF PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RBPJ RBPJK RBPSUH RBX1 RNF67 RNF75 ROC1 RPD3L1 RPS27A SKD SKIIP SKIP SKP1 SKP1A SNW1 STM2 TACE TAN1 TBL1 TBL1X TBL1XR1 TBLR1 TCEB1L UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2	Homo sapiens (human)
Macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit beta-2 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-2 5'-AMP-activated protein kinase subunit gamma-3 Activating molecule in BECN1-regulated autophagy protein 1 Autophagy protein 5 Autophagy-related protein 101 Autophagy-related protein 13 Autophagy-related protein 16-1 Autophagy-related protein 9A Autophagy-related protein 9B Beclin 1-associated autophagy-related key regulator Beclin-1 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 4b Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cysteine protease ATG4A Cysteine protease ATG4B Cysteine protease ATG4C Cysteine protease ATG4D Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic GTP-binding protein Rheb Gamma-aminobutyric acid receptor-associated protein-like 1 Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein-like 3 Gamma-aminobutyric acid receptor-associated protein Hamartin Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Microtubule-associated proteins 1A/1B light chain 3C Neutral amino acid transporter 9 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14 Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3 Phosphoinositide 3-kinase regulatory subunit 4 RB1-inducible coiled-coil protein 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Serine/threonine-protein kinase ULK1 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Tuberin UV radiation resistance-associated gene protein Ubiquitin-like modifier-activating enzyme ATG7 Ubiquitin-like protein ATG12 Ubiquitin-like-conjugating enzyme ATG10 Ubiquitin-like-conjugating enzyme ATG3 WD repeat domain phosphoinositide-interacting protein 1 WD repeat domain phosphoinositide-interacting protein 2 WD repeat domain phosphoinositide-interacting protein 3 WD repeat domain phosphoinositide-interacting protein 4	O43504 O43633 O43741 O75143 O75385 O94817 O95166 O95352 P42345 P49815 P54619 P54646 P60520 P63167 Q0VGL1 Q13131 Q13615 Q14457 Q15382 Q5MNZ6 Q5MNZ9 Q5VZM2 Q674R7 Q676U5 Q6IAA8 Q6ZNE5 Q7L523 Q7Z3C6 Q86TL0 Q8N122 Q8NBW4 Q8NCE2 Q8NEB9 Q8TDY2 Q8WUX9 Q8WYN0 Q92574 Q96CF2 Q96DT6 Q96FJ2 Q96FZ7 Q99570 Q9BSB4 Q9BVC4 Q9BXW4 Q9BY43 Q9BY60 Q9C0C7 Q9GZQ8 Q9H0R8 Q9H0Y0 Q9H1Y0 Q9H444 Q9H492 Q9HB90 Q9NQL2 Q9NT62 Q9P2Y5 Q9UGI9 Q9UGJ0 Q9UHA4 Q9UQN3 Q9Y2Q5 Q9Y3E7 Q9Y478 Q9Y484 Q9Y4P1 Q9Y4P8	AMBRA1 AMPK AMPK1 AMPK2 AMPKG3 APG10L APG12 APG12L APG16L APG3 APG3L APG4A APG4B APG4C APG4D APG5L APG7L APG9L1 APG9L2 ASP ATG10 ATG101 ATG12 ATG13 ATG14 ATG14L ATG16L1 ATG3 ATG4A ATG4B ATG4C ATG4D ATG5 ATG7 ATG9A ATG9B AUTL1 AUTL2 AUTL3 AUTL4 BC2 BECN1 C11orf59 C12orf44 C14orf123 C20orf178 C3orf29 C7orf59 CGI149 CHMP2 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 DCAF3 DLC1 DLC2 DNCL1 DNCLC1 DYNLL1 DYNLL2 FLC3A FLC3B FRAP FRAP1 FRAP2 GABARAP GABARAPL1 GABARAPL2 GABARAPL3 GBL GEC1 GEF2 GT197 HBXIP HDLC1 KIAA0203 KIAA0243 KIAA0371 KIAA0652 KIAA0722 KIAA0831 KIAA0943 KIAA1303 KIAA1736 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP1ALC3 MAP1LC3A MAP1LC3B MAP1LC3C MAP2K1IP1 MAPBPIP MAPKSP1 MLST8 MTMR14 MTMR3 MTOR NEDF NOS3AS PDRO PIK3C3 PIK3R4 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RAFT1 RAPT1 RAPTOR RB1CC1 RBICC RHEB RHEB2 ROBLD3 RPTOR RRAGA RRAGB RRAGC RRAGD SHAX1 SHAX2 SHAX3 SLC38A9 TSC TSC1 TSC2 TSC4 ULK1 URLC11 UVRAG VPS15 VPS20 VPS24 VPS34 WDR45 WDR45B WDR45L WDRX1 WDRXI4 WIPI1 WIPI2 WIPI3 WIPI4 WIPI49 XIP ZFYVE10	Homo sapiens (human)
Uptake of dietary cobalamins into enterocytes	Chymotrypsinogen B2 Chymotrypsinogen B Cobalamin binding intrinsic factor Cubilin Lysosomal cobalamin transport escort protein LMBD1 Lysosomal cobalamin transporter ABCD4 Protein amnionless Serine protease 1 Transcobalamin-1 Trypsin-3	O14678 O60494 P07477 P17538 P20061 P27352 P35030 Q6GPI1 Q9BXJ7 Q9NUN5	ABCD4 AMN C6orf209 CBLIF CTRB CTRB1 CTRB2 CUBN GIF IFCR IFMH LMBRD1 NESI PRSS1 PRSS3 PRSS4 PXMP1L TC1 TCN1 TRP1 TRY1 TRY3 TRY4 TRYP1	Homo sapiens (human)
TRIF-mediated programmed cell death	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 3 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	O00206 P08571 Q13158 Q13546 Q14790 Q86XR7 Q8IUC6 Q9Y572 Q9Y6Y9	CASP8 CD14 ESOP1 FADD LY96 MCH5 MD2 MORT1 PRVTIRB RIP RIP1 RIP3 RIPK1 RIPK3 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAM TRIF	Homo sapiens (human)
Interconversion of nucleotide di- and triphosphates	Adenylate kinase 2, mitochondrial Adenylate kinase 4, mitochondrial Adenylate kinase 7 Adenylate kinase 8 Adenylate kinase 9 Adenylate kinase isoenzyme 1 Adenylate kinase isoenzyme 5 Adenylate kinase isoenzyme 6 CTP synthase 1 CTP synthase 2 Deoxycytidylate deaminase Glutaredoxin-1 Guanylate kinase NAD(P)H pyrophosphatase NUDT13, mitochondrial Nucleoside diphosphate kinase 3 Nucleoside diphosphate kinase A Nucleoside diphosphate kinase B Nucleoside diphosphate kinase, mitochondrial Putative nucleoside diphosphate kinase Ribonucleoside-diphosphate reductase large subunit Ribonucleoside-diphosphate reductase subunit M2 B Ribonucleoside-diphosphate reductase subunit M2 Thioredoxin reductase 1, cytoplasmic Thioredoxin Thymidylate kinase Thymidylate synthase UMP-CMP kinase dCTP pyrophosphatase 1	O00746 O60361 P00568 P04818 P10599 P15531 P17812 P22392 P23919 P23921 P27144 P30085 P31350 P32321 P35754 P54819 Q13232 Q16774 Q16881 Q5TCS8 Q7LG56 Q86X67 Q96M32 Q96MA6 Q9H773 Q9NRF8 Q9Y3D8 Q9Y6K8	ADK2 AK1 AK2 AK3 AK3L1 AK4 AK5 AK6 AK7 AK8 AK9 AKD1 AKD2 C6orf199 C6orf224 C9orf98 CDC8 CINAP CMK CMPK CMPK1 CTPS CTPS1 CTPS2 DCTD DCTPP1 DTYMK GLRX GMK GMPK GRIM12 GRX GUK1 KDRF NDPKA NM23 NM23B NM23D NME1 NME2 NME2P1 NME3 NME4 NUDT13 P53R2 RR1 RR2 RRM1 RRM2 RRM2B TMPK TRDX TRX TRX1 TS TXN TXNRD1 TYMK TYMS UCK UMK UMPK XTP3TPA	Homo sapiens (human)
Defective EXT1 causes exostoses 1, TRPS2 and CHDS	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Exostosin-1 Exostosin-2 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4	O00468 O75056 O75487 P18827 P31431 P34741 P35052 P51654 P78333 P98160 Q16394 Q8N158 Q93063 Q9Y625	AGRIN AGRN EXT1 EXT2 GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HSPG1 HSPG2 KIAA0468 OCI5 SDC SDC1 SDC2 SDC3 SDC4	Homo sapiens (human)
Arachidonate production from DAG	Diacylglycerol lipase-alpha Diacylglycerol lipase-beta Lysophosphatidylserine lipase ABHD12 Monoacylglycerol lipase ABHD6 Monoglyceride lipase	Q8N2K0 Q8NCG7 Q99685 Q9BV23 Q9Y4D2	ABHD12 ABHD6 C11orf11 C20orf22 DAGLA DAGLB KIAA0659 MGLL NSDDR	Homo sapiens (human)
Degradation of GLI1 by the proteasome	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase RBX1 F-box/WD repeat-containing protein 1A Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein numb homolog S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein GLI1 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00231 O00232 O00487 O14818 O43242 P08151 P0CG47 P0CG48 P17612 P17980 P20618 P22612 P22694 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P49757 P51665 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P63208 Q13200 Q13616 Q15008 Q16186 Q96J02 Q99436 Q99460 Q9UMX1 Q9UNM6 Q9Y297	ADRM1 BTRC BTRCP C14orf41 C7orf76 CUL1 DSS1 EMC19 FBW1A FBXW1A GLI GLI1 GP110 HC2 HC3 HC8 HC9 HSPC ITCH KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU NUMB OCP2 PFAAP4 PKACA POH1 PRKACA PRKACB PRKACG PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUFU SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
RND1 GTPase cycle	Aldehyde dehydrogenase family 3 member A2 Ankyrin repeat domain-containing protein 26 Carboxypeptidase D Caveolin-1 DEP domain-containing protein 1B Desmoplakin Disks large homolog 5 Dystonin Ephrin type-A receptor 2 Epithelial-stromal interaction protein 1 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Flotillin-2 Girdin Growth factor receptor-bound protein 7 Inner nuclear membrane protein Man1 Kinase D-interacting substrate of 220 kDa Kinesin-like protein KIF14 Mucin-13 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plakophilin-4 Pleckstrin homology domain-containing family G member 5 Plexin-A1 Protein FAM135A Protein FAM83B RNA-binding motif protein, X chromosome Ras GTPase-activating protein nGAP Ras-related protein R-Ras2 Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Rho-related GTP-binding protein Rho6 Stathmin-2 Stress-induced-phosphoprotein 1 Thioredoxin-like protein 1 Transferrin receptor protein 1 Transmembrane protein 59 Tyrosine-protein phosphatase non-receptor type 13 UBX domain-containing protein 11 Vang-like protein 1 Vang-like protein 2 tRNA (34-2'-O)-methyltransferase regulator WDR6	O00459 O43396 O43559 O75976 O94827 P02786 P15924 P27986 P29317 P31948 P38159 P51648 P62070 Q03001 Q03135 Q12923 Q13017 Q14254 Q14451 Q15058 Q3V6T2 Q5T0W9 Q5T124 Q8TAA9 Q8TDM6 Q8WU20 Q8WUY9 Q92730 Q93045 Q96J88 Q99569 Q9BXS4 Q9H3R2 Q9NNW5 Q9NRY4 Q9P2D6 Q9UIW2 Q9UJF2 Q9ULH0 Q9ULK5 Q9UPS8 Q9Y2U8	ALDH10 ALDH3A2 ANKRD26 APE ARHGAP35 ARHGAP5 ARMS BP230 BP240 BPAG1 C1orf8 C6orf143 CAV CAV1 CCDC88A CPD DEPDC1B DLG5 DMH DRCC1 DSP DST DT ECK EPHA2 EPSTI1 ESA1 FALDH FAM135A FAM83B FLOT2 FRS2 FRS3 GRB1 GRB7 GRDN GRF1 GRLF1 HNRPG KIAA0042 KIAA0583 KIAA0720 KIAA0728 KIAA1074 KIAA1212 KIAA1215 KIAA1250 KIAA1411 KIAA1722 KIDINS220 KIF14 LEMD3 M17S1 MAN1 MUC13 NGAP NOV P190A PDLG PIK3R1 PIK3R2 PKP4 PLEKHG5 PLXN1 PLXNA1 PNP1 PTP1E PTPL1 PTPN13 RASAL2 RBMX RBMXP1 RECC RHO6 RHOGAP5 RND1 RRAS2 SCG10 SCGN10 SOC STB1 STB2 STIP1 STMN2 TC21 TFRC TMEM59 TRP32 TXL TXNL TXNL1 UBXD5 UBXN11 VANGL1 VANGL2 WDR6 XTP8 p190ARHOGAP	Homo sapiens (human)
Transcriptional regulation by small RNAs	Aladin DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 SUMO-protein ligase RanBP2 GTP-binding nuclear protein Ran Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Importin-8 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog Protein argonaute-1 Protein argonaute-2 Trinucleotide repeat-containing gene 6A protein mRNA export factor RAE1	A8CG34 O15397 O15504 O15514 O60814 O75694 P04908 P06899 P0C5Y9 P12270 P16104 P19387 P19388 P20671 P23527 P24928 P30876 P33778 P35658 P36954 P37198 P49790 P49792 P52434 P52435 P53803 P55735 P57053 P57740 P58876 P61218 P62487 P62805 P62807 P62826 P62875 P68431 P78406 P84243 Q12769 Q16777 Q16778 Q5SRE5 Q6FI13 Q71DI3 Q71UI9 Q7Z3B4 Q8N1F7 Q8N257 Q8NDV7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q93077 Q93079 Q96A08 Q96HA1 Q99567 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9BTX1 Q9BW27 Q9NRG9 Q9UKV8 Q9UKX7 Q9UL18	AAAS ADRACALA AGO1 AGO2 ARA24 C7orf14 CAGH26 CAIN CAN CG1 D3S1231E EIF2C1 EIF2C2 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 IPO8 KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KIAA1460 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF POM121 POM121A POM121C RAE1 RAN RANBP2 RANBP8 RPB7 SEC13 SEC13A SEC13L1 SEC13R TMEM48 TNRC6 TNRC6A TPR TSH2B	Homo sapiens (human)
Maturation of protein M	Membrane protein	P0DTC5	M	Homo sapiens (human)
The NLRP3 inflammasome	Alpha-hemolysin Amyloid-beta precursor protein Apoptosis-associated speck-like protein containing a CARD Caspase-1 Heat shock protein HSP 90-beta Heme oxygenase 1 NACHT, LRR and PYD domains-containing protein 3 Nuclear factor NF-kappa-B p100 subunit Nuclear factor NF-kappa-B p105 subunit P2X purinoceptor 7 Pannexin-1 Proline-serine-threonine phosphatase-interacting protein 1 Protein SGT1 homolog Pyrin Thioredoxin-interacting protein Thioredoxin Transcription factor p65	O15553 O43586 P05067 P08238 P09601 P09616 P10599 P19838 P29466 Q00653 Q04206 Q96P20 Q96RD7 Q99572 Q9H3M7 Q9ULZ3 Q9Y2Z0	A4 AD1 APP ASC C1orf7 CARD5 CASP1 CD2BP1 CIAS1 HMOX1 HO HO1 HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IL1BC IL1BCE LYT10 MEF MEFV MRS1 NALP3 NFKB1 NFKB2 NFKB3 NLRP3 P2RX7 PANX1 PSTPIP1 PYCARD PYPAF1 RELA SUGT1 TMS1 TRDX TRIM20 TRX TRX1 TXN TXNIP VDUP1 hla hly	Homo sapiens (human)
Signaling by ERBB2 TMD/JMD mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P07900 P19174 P29353 P35070 P56975 Q02297 Q07889 Q16543 Q8WWG1 Q96RT1 Q99075	BTC CDC37 CDC37A DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG GGF HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PLC1 PLCG1 SHC SHC1 SHCA SMDF SOS1	Homo sapiens (human)
Activation of G protein gated Potassium channels	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	O14610 O14775 O60262 O75899 P16520 P48050 P48051 P48544 P48549 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P63252 P78508 Q14500 Q92806 Q99712 Q9HAV0 Q9NPI9 Q9P2W3 Q9UBI6 Q9UBS5 Q9UK08	GABBR1 GABBR2 GIRK1 GIRK2 GIRK3 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPR51 GPRC3A GPRC3B IRK1 IRK2 IRK3 KATP2 KCNJ10 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ7 KCNJ9 KCNJN1	Homo sapiens (human)
Negative regulation of NOTCH4 signaling	14-3-3 protein zeta/delta 26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 E3 ubiquitin-protein ligase RBX1 Neurogenic locus notch homolog protein 4 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RAC-alpha serine/threonine-protein kinase S-phase kinase-associated protein 1 Transforming acidic coiled-coil-containing protein 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P31749 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P63104 P63208 Q13200 Q13616 Q15008 Q16186 Q99436 Q99460 Q99466 Q9UNM6 Q9Y6A5	ADRM1 AKT1 C7orf76 CUL1 DSS1 EMC19 ERIC1 GP110 HC2 HC3 HC8 HC9 HSPC INT3 KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NOTCH4 NU OCP2 PFAAP4 PKB POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RAC RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TACC3 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y YWHAZ Z	Homo sapiens (human)
Signaling by ROBO receptors	C-X-C chemokine receptor type 4 Ena/VASP-like protein Glypican-1 Leucine-rich repeat transmembrane protein FLRT3 Neuropilin-1 Profilin-1 Profilin-2 Protein enabled homolog Roundabout homolog 1 Roundabout homolog 2 Slit homolog 1 protein Slit homolog 2 protein Slit homolog 3 protein Stromal cell-derived factor 1 Vasodilator-stimulated phosphoprotein	O14786 O75093 O75094 O94813 P07737 P35052 P35080 P48061 P50552 P61073 Q8N8S7 Q9HCK4 Q9NZU0 Q9UI08 Q9Y6N7	CXCL12 CXCR4 DUTT1 ENAH EVL FLRT3 GPC1 KIAA0813 KIAA0814 KIAA1469 KIAA1568 MEGF4 MEGF5 MENA NRP NRP1 PFN1 PFN2 RNB6 ROBO1 ROBO2 SDF1 SDF1A SDF1B SLIL1 SLIL2 SLIL3 SLIT1 SLIT2 SLIT3 VASP VEGF165R	Homo sapiens (human)
O-glycosylation of TSR domain-containing proteins	A disintegrin and metalloproteinase with thrombospondin motifs 10 A disintegrin and metalloproteinase with thrombospondin motifs 12 A disintegrin and metalloproteinase with thrombospondin motifs 13 A disintegrin and metalloproteinase with thrombospondin motifs 14 A disintegrin and metalloproteinase with thrombospondin motifs 15 A disintegrin and metalloproteinase with thrombospondin motifs 16 A disintegrin and metalloproteinase with thrombospondin motifs 17 A disintegrin and metalloproteinase with thrombospondin motifs 18 A disintegrin and metalloproteinase with thrombospondin motifs 19 A disintegrin and metalloproteinase with thrombospondin motifs 1 A disintegrin and metalloproteinase with thrombospondin motifs 20 A disintegrin and metalloproteinase with thrombospondin motifs 2 A disintegrin and metalloproteinase with thrombospondin motifs 3 A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin and metalloproteinase with thrombospondin motifs 5 A disintegrin and metalloproteinase with thrombospondin motifs 6 A disintegrin and metalloproteinase with thrombospondin motifs 7 A disintegrin and metalloproteinase with thrombospondin motifs 8 A disintegrin and metalloproteinase with thrombospondin motifs 9 ADAMTS-like protein 1 ADAMTS-like protein 2 ADAMTS-like protein 3 ADAMTS-like protein 4 ADAMTS-like protein 5 Beta-1,3-glucosyltransferase GDP-fucose protein O-fucosyltransferase 2 Properdin SCO-spondin Semaphorin-5A Semaphorin-5B Somatomedin-B and thrombospondin type-1 domain-containing protein Spondin-1 Spondin-2 Thrombospondin type-1 domain-containing protein 1 Thrombospondin type-1 domain-containing protein 4 Thrombospondin type-1 domain-containing protein 7A Thrombospondin type-1 domain-containing protein 7B Thrombospondin-1 Thrombospondin-2	A2VEC9 O15072 O75173 O95450 P07996 P27918 P35442 P58397 P59510 P82987 Q13591 Q6UY14 Q6Y288 Q6ZMM2 Q6ZMP0 Q76LX8 Q86TH1 Q8IVN8 Q8N6G6 Q8TE56 Q8TE57 Q8TE58 Q8TE59 Q8TE60 Q8WXS8 Q9BUD6 Q9C0I4 Q9H324 Q9HCB6 Q9NS62 Q9P283 Q9P2N4 Q9UHI8 Q9UKP4 Q9UKP5 Q9UNA0 Q9UP79 Q9UPZ6 Q9Y2G5	ADAMTS1 ADAMTS10 ADAMTS11 ADAMTS12 ADAMTS13 ADAMTS14 ADAMTS15 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS19 ADAMTS2 ADAMTS20 ADAMTS21 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS6 ADAMTS7 ADAMTS8 ADAMTS9 ADAMTSL1 ADAMTSL2 ADAMTSL3 ADAMTSL4 ADAMTSL5 ADAMTSR1 ADMP2 B3GALTL B3GLCT B3GTL C21orf80 C8orf84 C9orf8 C9orf94 CFP DIL1 FUT13 KIAA0366 KIAA0605 KIAA0688 KIAA0762 KIAA0958 KIAA0960 KIAA1233 KIAA1312 KIAA1346 KIAA1445 KIAA1679 KIAA2029 KIAA2036 METH1 METH2 PCINP PCPNI PFC POFUT2 RPESP SBSPON SEMA5A SEMA5B SEMAF SEMAG SPON1 SPON2 SSPO SSPOP THBS1 THBS2 THSD1 THSD4 THSD6 THSD7A THSD7B TMTSP TSP TSP1 TSP2 TSRC1 VSGP	Homo sapiens (human)
Adenylate cyclase activating pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(olf) subunit alpha	O43306 O60266 O60503 O95622 P38405 P40145 P51828 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAL KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Signaling by CSF3 (G-CSF)	GRB2-associated-binding protein 2 GTPase KRas Granulocyte colony-stimulating factor receptor Granulocyte colony-stimulating factor Growth factor receptor-bound protein 2 Non-receptor tyrosine-protein kinase TYK2 SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase HCK Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein phosphatase non-receptor type 11	O14543 O15524 O60674 P01116 P07948 P08631 P09919 P23458 P29353 P29597 P40763 P42224 P42229 P43405 P51692 P62993 Q06124 Q99062 Q9UQC2	APRF ASH C17orf33 CIS3 CSF3 CSF3R GAB2 GCSF GCSFR GRB2 HCK JAK1 JAK1A JAK1B JAK2 JTK8 KIAA0571 KRAS KRAS2 LYN PTP2C PTPN11 RASK2 SHC SHC1 SHCA SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT1 STAT3 STAT5 STAT5A STAT5B SYK TIP3 TYK2	Homo sapiens (human)
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Neurotrophin-4 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O43559 P01111 P01112 P23560 P34130 Q06124 Q07889 Q16620 Q8WU20	BDNF FRS2 FRS3 HRAS HRAS1 NRAS NTF4 NTF5 NTRK2 PTP2C PTPN11 SHPTP2 SOS1 TRKB	Homo sapiens (human)
RHOD GTPase cycle	A-kinase anchor protein 12 Adenosine 5'-monophosphoramidase HINT2 Alpha-actinin-1 Caveolin-1 Cell surface glycoprotein MUC18 Copine-8 DEP domain-containing protein 1B Delta(14)-sterol reductase LBR Drebrin EF-hand domain-containing protein D2 Emerin Extended synaptotagmin-1 F-actin-capping protein subunit beta Filamin-A-interacting protein 1 Gamma-adducin Golgin subfamily A member 8R Inner nuclear membrane protein Man1 Lamin-B1 Lamina-associated polypeptide 2, isoforms beta/gamma Membrane-associated progesterone receptor component 2 Metalloreductase STEAP3 Motile sperm domain-containing protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plexin-A1 Plexin-B1 Protein ERGIC-53 Protein diaphanous homolog 1 Protein diaphanous homolog 3 Rabankyrin-5 Rac GTPase-activating protein 1 Ras-related protein Rab-7a Rho GTPase-activating protein 12 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 5 Rho-related GTP-binding protein RhoD Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase PAK 6 Serine/threonine-protein kinase VRK2 Sodium bicarbonate cotransporter 3 Starch-binding domain-containing protein 1 Torsin-1A-interacting protein 1 Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C WASP homolog-associated protein with actin, membranes and microtubules	A7KAX9 I6L899 O00212 O00459 O15173 O43157 O60610 O95210 O95292 P12814 P20700 P27986 P42167 P43121 P47756 P49257 P50402 P51149 Q02952 Q03135 Q07960 Q13017 Q14739 Q15836 Q16643 Q5JTV8 Q5T5U3 Q658P3 Q68EM7 Q7Z7B0 Q86Y07 Q86YQ8 Q8IWW6 Q8NHP6 Q8TAA9 Q8TF30 Q8WUY9 Q96C19 Q9BSJ8 Q9BX68 Q9C0H5 Q9H0H5 Q9NQU5 Q9NRY4 Q9NSV4 Q9P286 Q9P2R3 Q9UEY8 Q9UIW2 Q9UNA1 Q9Y2U8 Q9Y6M7	ACTN1 ADD3 ADDL AKAP12 AKAP250 ANKFY1 ANKHZN ARHD ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 BT CAPZB CAV CAV1 CDC42GAP CPNE8 D0S117E DBN1 DEPDC1B DG6 DIAP1 DIAP3 DIAPH1 DIAPH3 EDMD EFHD2 EMD ERGIC53 ESYT1 F5F8D FAM62A FILIP1 GOLGA8R GRAF GRB1 GRF1 GRIT GRLF1 HINT2 KIAA0407 KIAA0621 KIAA0712 KIAA0747 KIAA1255 KIAA1264 KIAA1275 KIAA1424 KIAA1478 KIAA1688 KIAA1722 KIAA1971 LAP1 LAP2 LBR LEMD3 LMAN1 LMN2 LMNB LMNB1 MAN1 MBC2 MCAM MGCRACGAP MOSPD2 MUC18 NBC2 NBC2B NBC3 NBCn1 NOV OPHN1L P190A PAK5 PAK6 PAK7 PGRMC2 PIK3R1 PIK3R2 PLXN1 PLXN5 PLXNA1 PLXNB1 PMBP RAB7 RAB7A RACGAP1 RHOD RHOGAP1 RHOGAP5 RICH1 RICS SBC2 SEP SLC4A6 SLC4A7 STA STB2 STBD1 STEAP3 SWS1 SYB3 TMPO TOR1AIP1 TSAP6 VAMP3 VANGL1 VAPB VRK2 WHAMM WHDC1 XTP8 p190ARHOGAP	Homo sapiens (human)

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