GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1676 - 1700** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Formation of HIV-1 elongation complex containing HIV-1 Tat	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-T1 Cyclin-dependent kinase 7 Cyclin-dependent kinase 9 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongin-A2 Elongin-A Elongin-B Elongin-C FACT complex subunit SPT16 FACT complex subunit SSRP1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Negative elongation factor A Negative elongation factor B Negative elongation factor C/D Negative elongation factor E Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Protein Tat RNA polymerase II elongation factor ELL RNA polymerase II subunit A C-terminal domain phosphatase Transcription elongation factor A protein 1 Transcription elongation factor SPT4 Transcription elongation factor SPT5	O00267 O15514 O60563 P04608 P13984 P18074 P18615 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P35269 P36954 P50613 P50750 P51946 P51948 P52298 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P63272 Q08945 Q09161 Q13888 Q13889 Q14241 Q15369 Q15370 Q6ZYL4 Q8IXH7 Q8IYF1 Q8WX92 Q92759 Q9H3P2 Q9Y5B0 Q9Y5B9	BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CBP20 CBP80 CCNH CCNT1 CDC2L4 CDK7 CDK9 CDKN7 COBRA1 CTDP1 ELL ELOA ELOA2 ELOB ELOC ERCC2 ERCC3 FACT140 FACT80 FACTP140 FCP1 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S KIAA1182 MAT1 MNAT1 MO15 NCBP NCBP1 NCBP2 NELFA NELFB NELFCD NELFD NELFE POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RD RDBP RNF66 RPB7 SPT4H SPT5 SPT5H SSRP1 STK1 SUPT16H SUPT4H SUPT4H1 SUPT5H TAK TCEA1 TCEB1 TCEB2 TCEB3 TCEB3B TCEB3L TFIIS TH1 TH1L TTDA WHSC2 XPB XPBC XPD XPDC tat	Homo sapiens (human)
Rev-mediated nuclear export of HIV RNA	Aladin E3 SUMO-protein ligase RanBP2 Exportin-1 GTP-binding nuclear protein Ran Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein Rev Protein SEC13 homolog Ran GTPase-activating protein 1 Ran-specific GTPase-activating protein Regulator of chromosome condensation mRNA export factor RAE1	A8CG34 O14980 O15504 O75694 P04618 P12270 P18754 P35658 P37198 P43487 P46060 P49790 P49792 P55735 P57740 P62826 P78406 Q12769 Q5SRE5 Q7Z3B4 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UKX7	AAAS ADRACALA ARA24 C7orf14 CAIN CAN CG1 CHC1 CRM1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KIAA1835 MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C RAE1 RAN RANBP1 RANBP2 RANGAP1 RCC1 SD SEC13 SEC13A SEC13L1 SEC13R TMEM48 TPR XPO1 rev	Homo sapiens (human)
Neurexins and neuroligins	Amyloid-beta A4 precursor protein-binding family A member 1 Amyloid-beta A4 precursor protein-binding family A member 2 Amyloid-beta A4 precursor protein-binding family A member 3 Band 4.1-like protein 1 Band 4.1-like protein 2 Band 4.1-like protein 3 Band 4.1-like protein 5 Brain-enriched guanylate kinase-associated protein Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Disks large-associated protein 1 Disks large-associated protein 2 Disks large-associated protein 3 Disks large-associated protein 4 Drebrin-like protein Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2A Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2C Glutamate receptor ionotropic, NMDA 2D Homer protein homolog 1 Homer protein homolog 2 Homer protein homolog 3 Leucine-rich repeat transmembrane neuronal protein 1 Leucine-rich repeat transmembrane neuronal protein 2 Leucine-rich repeat transmembrane neuronal protein 3 Leucine-rich repeat transmembrane neuronal protein 4 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 5 Neurexin-1-beta Neurexin-1 Neurexin-2-beta Neurexin-2 Neurexin-3-beta Neurexin-3 Neuroligin-1 Neuroligin-2 Neuroligin-3 Neuroligin-4, X-linked Neuroligin-4, Y-linked PDZ and LIM domain protein 5 Peripheral plasma membrane protein CASK Protein 4.1 Protein lin-7 homolog A Protein lin-7 homolog B Protein lin-7 homolog C SH3 and multiple ankyrin repeat domains protein 1 SH3 and multiple ankyrin repeat domains protein 2 SH3 and multiple ankyrin repeat domains protein 3 Sharpin Signal-induced proliferation-associated 1-like protein 1 Synaptotagmin-10 Synaptotagmin-12 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-7 Synaptotagmin-9 Syntaxin-1A Syntaxin-binding protein 1	O14490 O14910 O14936 O15399 O43166 O43300 O43491 O43581 O95886 O96018 P11171 P21579 P41594 P58400 P58401 P61764 P78352 Q02410 Q05586 Q12879 Q13224 Q13255 Q14957 Q15700 Q16623 Q6XYQ8 Q86SS6 Q86UE6 Q86VH4 Q86VH5 Q86YM7 Q8IV01 Q8N0W4 Q8N2Q7 Q8N9I0 Q8NFZ3 Q8NFZ4 Q92796 Q96HC4 Q99767 Q9BUH8 Q9BYB0 Q9H0F6 Q9H4G0 Q9HAP6 Q9HCM4 Q9HDB5 Q9NSB8 Q9NSC5 Q9NUP9 Q9NZ94 Q9P1A6 Q9P2S2 Q9UJU6 Q9ULB1 Q9UPX8 Q9Y2H0 Q9Y2J2 Q9Y4C0 Q9Y566	APBA1 APBA2 APBA3 BEGAIN C14orf60 C8orf68 CASK CMAP CORTBP1 DAL1 DAP1 DAP2 DAP3 DAP4 DBNL DLG2 DLG3 DLG4 DLGAP1 DLGAP2 DLGAP3 DLGAP4 E41P E6TP1 ENH EPB41 EPB41L1 EPB41L2 EPB41L3 EPB41L5 ERICH1-AS1 GKAP GPRC1A GPRC1E GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRM1 GRM5 GluN2D HOMER1 HOMER2 HOMER3 KIAA0338 KIAA0416 KIAA0440 KIAA0578 KIAA0743 KIAA0921 KIAA0951 KIAA0964 KIAA0987 KIAA1022 KIAA1070 KIAA1232 KIAA1260 KIAA1366 KIAA1446 KIAA1480 KIAA1548 KIAA1650 LIN2 LIN7A LIN7B LIN7C LRRN2 LRRTM1 LRRTM2 LRRTM3 LRRTM4 MALS1 MALS2 MALS3 MGLUR1 MGLUR5 MINT1 MINT2 MINT3 NL3 NLGN1 NLGN2 NLGN3 NLGN4 NLGN4X NLGN4Y NMDAR1 NMDAR2A NMDAR2B NMDAR2C NMDAR2D NRXN1 NRXN2 NRXN3 PCANAP7 PDLIM5 PROSAP1 PROSAP2 PSAP2 PSD95 SAPAP4 SH3P7 SHANK1 SHANK2 SHANK3 SHARPIN SIPA1L1 SIPL1 STX1 STX1A STXBP1 SVP65 SYN47 SYT SYT1 SYT10 SYT12 SYT2 SYT7 SYT9 UNC18A VELI1 VELI2 VELI3 X11 X11L X11L2	Homo sapiens (human)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor-associated factor 2 TNF receptor-associated factor 3 Tumor necrosis factor ligand superfamily member 11 Tumor necrosis factor ligand superfamily member 12 Tumor necrosis factor ligand superfamily member 13B Tumor necrosis factor ligand superfamily member 14 Tumor necrosis factor receptor superfamily member 11A Tumor necrosis factor receptor superfamily member 12A Tumor necrosis factor receptor superfamily member 13C Tumor necrosis factor receptor superfamily member 3	O14788 O43508 O43557 P01374 P29965 P36941 Q06643 Q12933 Q13114 Q13489 Q13490 Q96RJ3 Q99558 Q9NP84 Q9Y275 Q9Y6Q6	API1 API2 APO3L BAFF BAFFR BIRC2 BIRC3 BLYS BR3 CAP-1 CD40L CD40LG CRAF1 D12S370 DR3LG FN14 HVEML LIGHT LTA LTB LTBR MAP3K14 MIHB MIHC NIK OPGL RANK RANKL RNF48 RNF49 TALL1 TNFB TNFC TNFCR TNFR3 TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF3 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF20 TNFSF3 TNFSF5 TRAF2 TRAF3 TRAFAMN TRANCE TRAP TRAP3 ZTNF4	Homo sapiens (human)
Transport and synthesis of PAPS	Adenosine 3'-phospho 5'-phosphosulfate transporter 1 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Sulfate anion transporter 1 Sulfate transporter	O43252 O95340 P50443 Q8TB61 Q9H1N7 Q9H2B4	ATPSK1 ATPSK2 C6orf196 DTD DTDST PAPSS PAPSS1 PAPSS2 PAPST1 PAPST2 SAT1 SLC26A1 SLC26A2 SLC35B2 SLC35B3	Homo sapiens (human)
Defective MOGS causes CDG-2b	Mannosyl-oligosaccharide glucosidase	Q13724	GCS1 MOGS	Homo sapiens (human)
IL-6-type cytokine receptor ligand interactions	Cardiotrophin-1 Cardiotrophin-like cytokine factor 1 Ciliary neurotrophic factor receptor subunit alpha Ciliary neurotrophic factor Cytokine receptor-like factor 1 Interleukin-11 receptor subunit alpha Interleukin-11 Interleukin-31 receptor subunit alpha Interleukin-31 Interleukin-6 receptor subunit beta Leukemia inhibitory factor receptor Leukemia inhibitory factor Non-receptor tyrosine-protein kinase TYK2 Oncostatin-M-specific receptor subunit beta Oncostatin-M Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2	O60674 O75462 P13725 P15018 P20809 P23458 P26441 P26992 P29597 P40189 P42702 Q14626 Q16619 Q6EBC2 Q8NI17 Q99650 Q9UBD9	BSF3 CLC CLCF1 CNTF CNTFR CRL3 CRLF1 CTF1 GPL HILDA IL11 IL11RA IL31 IL31RA IL6ST JAK1 JAK1A JAK1B JAK2 LIF LIFR NNT1 OSM OSMR OSMRB TYK2	Homo sapiens (human)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	ATPase GET3 Amyloid-beta precursor protein Emerin Golgi to ER traffic protein 4 homolog Guided entry of tail-anchored proteins factor 1 Guided entry of tail-anchored proteins factor CAMLG Heme oxygenase 1 Large proline-rich protein BAG6 Major prion protein Otoferlin Protein transport protein Sec61 subunit beta Protein transport protein Sec61 subunit gamma Small glutamine-rich tetratricopeptide repeat-containing protein alpha Stress-associated endoplasmic reticulum protein 1 Syntaxin-1A Syntaxin-5 Ubiquitin-like protein 4A Vesicle-associated membrane protein 2 Vesicle-associated membrane protein-associated protein A	O00258 O43681 O43765 P04156 P05067 P09601 P11441 P46379 P49069 P50402 P60059 P60468 P63027 Q13190 Q16623 Q7L5D6 Q9HC10 Q9P0L0 Q9Y6X1	A4 AD1 ALTPRP APP ARSA ASNA1 BAG6 BAT3 C7orf20 CAML CAMLG CEE CHD5 DXS254E EDMD EMD FER1L2 G3 GDX GET1 GET2 GET3 GET4 HMOX1 HO HO1 OTOF PRIP PRNP PRP RAMP4 SEC61B SEC61G SERP1 SGT SGT1 SGTA STA STX1 STX1A STX5 STX5A SYB2 TRC35 TRC40 UBL4 UBL4A VAMP2 VAP33 VAPA WRB	Homo sapiens (human)
Insulin receptor recycling	Cathepsin D Insulin receptor Insulin-degrading enzyme Insulin Receptor-type tyrosine-protein phosphatase F Tyrosine-protein phosphatase non-receptor type 1 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C 2 V-type proton ATPase subunit D V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G 3 V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit e 2	O15342 O75348 O95670 P01308 P06213 P07339 P10586 P14735 P15313 P18031 P21281 P21283 P27449 P36543 P38606 P61421 Q13488 Q15904 Q16864 Q8N8Y2 Q8NEY4 Q8NHE4 Q93050 Q96A05 Q96LB4 Q99437 Q9HBG4 Q9UI12 Q9Y487 Q9Y5K8	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6E1 ATP6E2 ATP6EL2 ATP6F ATP6G ATP6G1 ATP6G2 ATP6G3 ATP6H ATP6IP1 ATP6J ATP6L ATP6M ATP6N1 ATP6N1A ATP6N1B ATP6N1C ATP6N2 ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A3 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V0E2L ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1EL2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATPL C7orf32 CPSD CTSD IDE INS INSR LAR NG38 PTP1B PTPN1 PTPRF TCIRG1 VATB VATC VATD VATF VATPS1 VPATPD VPP1 VPP2 VPP3 XAP3	Homo sapiens (human)
STAT5 Activation	Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 2 Receptor-type tyrosine-protein kinase FLT3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein phosphatase non-receptor type 11	P36888 P42229 P49771 P51692 Q06124 Q9UQC2	CD135 FLK2 FLT3 FLT3LG GAB2 KIAA0571 PTP2C PTPN11 SHPTP2 STAT5 STAT5A STAT5B STK1	Homo sapiens (human)
Defective DPM2 causes CDG-1u	Dolichol phosphate-mannose biosynthesis regulatory protein Dolichol-phosphate mannosyltransferase subunit 1 Dolichol-phosphate mannosyltransferase subunit 3	O60762 O94777 Q9P2X0	DPM1 DPM2 DPM3	Homo sapiens (human)
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein FLICE inhibitory protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor-interacting serine/threonine-protein kinase 1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 2 Toll-like receptor 4 Tumor necrosis factor ligand superfamily member 10 Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein Viral CASP8 and FADD-like apoptosis regulator	O00206 O00220 O14763 P08571 P25445 P48023 P50591 Q12933 Q13158 Q13546 Q14790 Q15628 Q76RF1 Q86XR7 Q8IUC6 Q98325 Q9Y6Y9	APO2 APO2L APT1 APT1LG1 CASP8 CD14 CD95L DR4 DR5 ESOP1 FADD FAS FAS1 FASL FASLG KILLER LY96 MC159L MCH5 MD2 MORT1 ORF71 PRVTIRB RIP RIP1 RIPK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TNFRSF10A TNFRSF10B TNFRSF6 TNFSF10 TNFSF6 TRADD TRAF2 TRAIL TRAILR1 TRAILR2 TRAM TRAP3 TRICK2 TRIF ZTNFR9	Homo sapiens (human)
tRNA processing in the nucleus	ATP-dependent RNA helicase DDX1 Aladin Ashwin CCA tRNA nucleotidyltransferase 1, mitochondrial Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 4 Cleavage stimulation factor subunit 2 E3 SUMO-protein ligase RanBP2 Exportin-T GTP-binding nuclear protein Ran Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Polyribonucleotide 5'-hydroxyl-kinase Clp1 Protein FAM98B Protein SEC13 homolog Protein archease RNA transcription, translation and transport factor protein RNA-splicing ligase RtcB homolog Ribonuclease P protein subunit p14 Ribonuclease P protein subunit p20 Ribonuclease P protein subunit p21 Ribonuclease P protein subunit p25 Ribonuclease P protein subunit p29 Ribonuclease P protein subunit p30 Ribonuclease P protein subunit p38 Ribonuclease P protein subunit p40 Ribonuclease P/MRP protein subunit POP5 Ribonucleases P/MRP protein subunit POP1 Zinc phosphodiesterase ELAC protein 2 mRNA export factor RAE1 tRNA-splicing endonuclease subunit Sen15 tRNA-splicing endonuclease subunit Sen2 tRNA-splicing endonuclease subunit Sen34 tRNA-splicing endonuclease subunit Sen54	A8CG34 O15504 O43592 O75694 O75817 O75818 O95059 O95639 O95707 P12270 P33240 P35658 P37198 P49790 P49792 P55735 P57740 P62826 P78345 P78346 P78406 Q10570 Q12769 Q52LJ0 Q5SRE5 Q7Z3B4 Q7Z6J9 Q8IWT0 Q8N1F7 Q8NCE0 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q8WW01 Q92499 Q92621 Q92989 Q969H6 Q96HA1 Q96Q11 Q99567 Q99575 Q9BQ52 Q9BSV6 Q9BTX1 Q9BUL9 Q9BVC5 Q9BW27 Q9H633 Q9NRG9 Q9UKX7 Q9Y224 Q9Y3I0	AAAS ADRACALA ARA24 ARCH C14orf166 C1orf19 C22orf28 C2orf49 C6orf135 C7orf14 CAIN CAN CAT60 CG1 CLP1 CPSF1 CPSF160 CPSF30 CPSF4 CSTF2 D3S1231E DDX1 ELAC2 FAM98B HEAB HPC2 KIAA0023 KIAA0061 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 LENG5 MP44 MRNP41 NAR NDC1 NEB1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 POM121 POM121A POM121C POP1 POP4 POP5 POP7 RAE1 RAN RANBP2 RNASEP1 RNASEP2 RPP14 RPP20 RPP21 RPP25 RPP29 RPP30 RPP38 RPP40 RTCB RTRAF SEC13 SEC13A SEC13L1 SEC13R SEN15 SEN2 SEN34 SEN54 TMEM48 TPR TRNT1 TSEN15 TSEN2 TSEN34 TSEN54 XPOT ZBTB8OS	Homo sapiens (human)
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 E3 ubiquitin-protein ligase RNF31 E3 ubiquitin-protein ligase XIAP Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator OTU domain-containing protein 1 OTU domain-containing protein 7B Optineurin RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor-interacting serine/threonine-protein kinase 1 Sharpin Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 1 TNF receptor-associated factor 2 Tumor necrosis factor alpha-induced protein 3 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 21 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD	O14920 O15111 O43318 O75604 P01375 P19438 P21580 P63244 P98170 Q12933 Q13077 Q13107 Q13489 Q13490 Q13546 Q15628 Q15750 Q5VV17 Q6GQQ9 Q8N5C8 Q96CV9 Q96EP0 Q9BYM8 Q9H0F6 Q9NQC7 Q9NYJ8 Q9UK80 Q9UM82 Q9Y6K9	API1 API2 API3 BIRC2 BIRC3 BIRC4 C20orf18 CHUK CYLD CYLD1 DUBA7 EBI6 FIP2 FIP3 GLC1E GNB2L1 HIP7 HYPL IAP3 IKBKB IKBKG IKKA IKKB KIAA0733 KIAA0757 KIAA0849 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MIHB MIHC NEMO NRP OPTN OTDC1 OTUD1 OTUD7B OTUD7C PD1 RACK1 RBCK1 RIP RIP1 RIPK1 RNF31 RNF48 RNF49 RNF54 SHARPIN SIPL1 SPATA2 TAB1 TAB2 TAB3 TAK1 TCF16 TNF TNFA TNFAIP3 TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF1 TRAF2 TRAP3 UBCE7IP3 UBP41 UNP UNPH USP2 USP21 USP23 USP4 XAP3 XAP4 XIAP ZA20D1 ZIBRA	Homo sapiens (human)
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin-3 Drebrin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoproteins C1/C2 Hsp90 co-chaperone Cdc37 PH-interacting protein RNA-binding motif protein, X chromosome RNA-binding protein Musashi homolog 2 Rho-related BTB domain-containing protein 2 Serine/arginine repetitive matrix protein 1 Serine/threonine-protein kinase 38 Spliceosome RNA helicase DDX39B T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Tropomodulin-3 Twinfilin-1 Unconventional myosin-VI	O43396 P07900 P07910 P08238 P12814 P38159 P40227 P62995 P63261 P78371 Q12792 Q13618 Q13838 Q15208 Q16543 Q16643 Q8IYB3 Q8WWQ0 Q96DH6 Q99832 Q9BYZ6 Q9NYL9 Q9UM54	99D8.1 ACTG ACTG1 ACTN1 BAT1 CCT2 CCT6 CCT6A CCT7 CCTB CCTH CCTZ CDC37 CDC37A CUL3 D0S117E DBC2 DBN1 DCAF14 DDX39B HNRNPC HNRPC HNRPG HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0389 KIAA0617 KIAA0717 MSI2 MYO6 NDR1 NIP7-1 PHIP PTK9 RBMX RBMXP1 RHOBTB2 SFRS10 SRM160 SRRM1 STK38 TMOD3 TRA2B TRP32 TWF1 TXL TXNL TXNL1 UAP56 WDR11	Homo sapiens (human)
DAG and IP3 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Protein kinase C delta type Protein kinase C epsilon type S-adenosylhomocysteine hydrolase-like protein 1	O43865 P19174 Q02156 Q05655 Q14571 Q14573 Q14643	AHCYL1 DCAL INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 PKCD PKCE PLC1 PLCG1 PRKCD PRKCE XPVKONA	Homo sapiens (human)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Free fatty acid receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15	O14842 O95837 P29992 P30679 P50148 Q00722 Q01970 Q9NQ66	FFAR1 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ GPR40 KIAA0581 PLCB1 PLCB2 PLCB3	Homo sapiens (human)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	3 beta-hydroxysteroid dehydrogenase type 7 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Acyl-coenzyme A thioesterase 8 Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1 member C2 Aldo-keto reductase family 1 member C3 Aldo-keto reductase family 1 member C4 Aldo-keto reductase family 1 member D1 Alpha-methylacyl-CoA racemase Bile acid receptor Bile acid-CoA Bile salt export pump Cytochrome P450 7A1 Cytochrome P450 7B1 Long-chain fatty acid transport protein 2 Long-chain fatty acid transport protein 5 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal multifunctional enzyme type 2 Retinoic acid receptor RXR-alpha Sterol 26-hydroxylase, mitochondrial	O14734 O14975 O75881 O95342 P17516 P19793 P22680 P42330 P51659 P51857 P52895 Q02318 Q04828 Q14032 Q15596 Q15788 Q96RI1 Q99424 Q9H2F3 Q9UHK6 Q9UNU6 Q9Y2P5	ABCB11 ACOT8 ACOX2 ACSB ACSVL1 ACSVL6 ACTEIII AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 AMACR BAAT BAR BHLHE74 BHLHE75 BSEP CHDR CYP12 CYP27 CYP27A1 CYP7 CYP7A1 CYP7B1 CYP8B1 DDH DDH1 DDH2 EDH17B4 FACVL1 FACVL3 FATP2 FATP5 FXR HRR1 HSD17B4 HSD17B5 HSD3B7 KIAA0119 NCOA1 NCOA2 NR1H4 NR2B1 PGFS PTE1 RIP14 RXRA SDR8C1 SLC27A2 SLC27A5 SRC1 SRC2 SRD5B1 TIF2 VLACS	Homo sapiens (human)
Mitochondrial Fatty Acid Beta-Oxidation	3-ketoacyl-CoA thiolase, mitochondrial Acetyl-coenzyme A thioesterase Acyl carrier protein, mitochondrial Acyl-CoA dehydrogenase family member 10 Acyl-CoA dehydrogenase family member 11 Acyl-CoA-binding domain-containing protein 6 Acyl-CoA-binding domain-containing protein 7 Acyl-CoA-binding protein Acyl-coenzyme A thioesterase 11 Acyl-coenzyme A thioesterase 13 Acyl-coenzyme A thioesterase 1 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 9, mitochondrial Acyl-coenzyme A thioesterase THEM4 Acyl-coenzyme A thioesterase THEM5 Cytosolic acyl coenzyme A thioester hydrolase Malonyl-CoA-acyl carrier protein transacylase, mitochondrial Medium-chain acyl-CoA ligase ACSF2, mitochondrial Phosphatidylcholine transfer protein Putative cytosolic acyl coenzyme A thioester hydrolase-like	O00154 O14561 P07108 P42765 P49753 Q5T1C6 Q6JQN1 Q6ZUV0 Q709F0 Q86TX2 Q8IVS2 Q8N1Q8 Q8N6N7 Q8WXI4 Q8WYK0 Q96CM8 Q9BR61 Q9NPJ3 Q9UKL6 Q9Y305	ACAA2 ACAD10 ACAD11 ACBD6 ACBD7 ACOT1 ACOT11 ACOT12 ACOT13 ACOT15 ACOT2 ACOT7 ACOT7L ACOT9 ACSF2 BACH BACHL BFIT CACH CACH1 CTE1 CTMP DBI KIAA0707 MCAT MT NDUFAB1 PCTP PTE2 PTE2A STARD15 STARD2 THEA THEM2 THEM4 THEM5	Homo sapiens (human)
Uptake and function of diphtheria toxin	CD9 antigen Diphtheria toxin Elongation factor 2 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Proheparin-binding EGF-like growth factor Thioredoxin reductase 1, cytoplasmic	P00588 P07900 P08238 P13639 P21926 Q16881 Q99075	CD9 DTR DTS EEF2 EF2 GRIM12 HBEGF HEGFL HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KDRF MIC3 TSPAN29 TXNRD1	Homo sapiens (human)
Trafficking of AMPA receptors	A-kinase anchor protein 5 Band 4.1-like protein 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Disks large homolog 1 Disks large homolog 4 E3 ubiquitin-protein ligase Mdm2 Glutamate receptor 1 Glutamate receptor 3 Glutamate receptor 4 Unconventional myosin-VI Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-3 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-8 subunit	O60359 P24588 P42261 P42263 P48058 P78352 Q00987 Q12959 Q13554 Q13555 Q13557 Q8WXS5 Q9H4G0 Q9UBN1 Q9UM54 Q9UQM7 Q9Y698	AKAP5 AKAP79 CACNG2 CACNG3 CACNG4 CACNG6 CACNG8 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG DLG1 DLG4 EPB41L1 GLUA1 GLUH1 GLUR1 GLUR3 GLUR4 GLURC GRIA1 GRIA3 GRIA4 GluA3 GluA4 KIAA0338 KIAA0389 KIAA0968 MDM2 MYO6 PSD95	Homo sapiens (human)
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15455 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q8IUC6 Q92844 Q96CV9 Q9UHD2	CAP-1 CRAF1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TLR3 TRAF2 TRAF3 TRAFAMN TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Defective translocation of RB1 mutants to the nucleus	Retinoblastoma-associated protein	P06400	RB1	Homo sapiens (human)
PI3K events in ERBB4 signaling	Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor	O14511 O14944 P27986 P35070 P42336 P56975 Q02297 Q8WWG1 Q99075	BTC DTR DTS EREG GGF GRB1 HBEGF HEGFL HGL HRGA NDF NRG1 NRG2 NRG3 NRG4 NTAK PIK3CA PIK3R1 SMDF	Homo sapiens (human)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	E3 ubiquitin-protein ligase pellino homolog 1 E3 ubiquitin-protein ligase pellino homolog 2 E3 ubiquitin-protein ligase pellino homolog 3 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B essential modulator TNF receptor-associated factor 6 Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 P51617 P61088 Q13404 Q8N2H9 Q96FA3 Q9HAT8 Q9Y4K3 Q9Y6K9	BLU CHUK CROC1 FIP3 IKBKB IKBKG IKKA IKKB IRAK IRAK1 NEMO PELI1 PELI2 PELI3 PRISM RNF85 TCF16 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)

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