GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1901 - 1925** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Defective ABCG8 causes GBD4 and sitosterolemia	ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8	Q9H221 Q9H222	ABCG5 ABCG8	Homo sapiens (human)
Influenza Infection	Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821	HA M NA NP NS PA PB1 PB2	Homo sapiens (human)
Defective GFPT1 causes CMSTA1	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1	Q06210	GFAT GFPT GFPT1	Homo sapiens (human)
Dissolution of Fibrin Clot	Alpha-2-antiplasmin Annexin A2 Glia-derived nexin Histidine-rich glycoprotein Plasminogen activator inhibitor 1 Plasminogen activator inhibitor 2 Plasminogen Protein S100-A10 Serpin B6 Serpin B8 Tissue-type plasminogen activator Urokinase plasminogen activator surface receptor Urokinase-type plasminogen activator	P00747 P00749 P00750 P04196 P05120 P05121 P07093 P07355 P08697 P35237 P50452 P60903 Q03405	AAP ANX2 ANX2L4 ANX2LG ANXA2 CAL1H CAL1L CLP11 HRG LPC2D MO3 PAI1 PAI2 PI6 PI7 PI8 PLANH1 PLANH2 PLAT PLAU PLAUR PLG PLI PN1 PTI S100A10 SERPINB2 SERPINB6 SERPINB8 SERPINE1 SERPINE2 SERPINF2 UPAR	Homo sapiens (human)
Signaling by activated point mutants of FGFR1	Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 1	P05230 P08620 P09038 P10767 P11362 P31371 Q9GZV9 Q9NP95	BFGFR CEK FGF1 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFBR FGFR1 FLG FLT2 HBGFR HST HST2 HSTF1 HSTF2 HYPF KS3	Homo sapiens (human)
NGF processing	Beta-nerve growth factor Furin Proprotein convertase subtilisin/kexin type 5 Proprotein convertase subtilisin/kexin type 6	P01138 P09958 P29122 Q92824	FUR FURIN NGF NGFB PACE PACE4 PC5 PC6 PCSK3 PCSK5 PCSK6	Homo sapiens (human)
TP53 Regulates Transcription of Death Receptors and Ligands	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3 Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily member 10C Tumor necrosis factor receptor superfamily member 10D Tumor necrosis factor receptor superfamily member 6 Tumor protein 63 Tumor protein p73	O00220 O14763 O14798 O15350 P04637 P17936 P25445 Q13625 Q86XT9 Q96KQ4 Q9H3D4 Q9UBN6	APO2 APT1 ASPP1 ASPP2 BBP DCR1 DCR2 DR4 DR5 FAS FAS1 IBP3 IGFBP3 KET KIAA0771 KILLER LIT P53 P63 P73 P73H P73L PPP1R13B TMEM219 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF6 TP53 TP53BP2 TP63 TP73 TP73L TRAILR1 TRAILR2 TRAILR3 TRAILR4 TRICK2 TRID TRUNDD ZTNFR9	Homo sapiens (human)
Potassium transport channels	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 1 Inward rectifier potassium channel 16	P48048 P78508 Q9NPI9	KCNJ1 KCNJ10 KCNJ16 ROMK1	Homo sapiens (human)
GAB1 signalosome	Amphiregulin Epidermal growth factor receptor Epigen GRB2-associated-binding protein 1 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha Tyrosine-protein kinase CSK Tyrosine-protein phosphatase non-receptor type 11	O14944 P00533 P01133 P01135 P12931 P15514 P27986 P35070 P41240 P42336 P49023 Q06124 Q13480 Q6UW88 Q99075 Q9NWQ8	AREG AREGB BTC CBP CSK DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG GAB1 GRB1 HBEGF HEGFL HER1 PAG PAG1 PIK3CA PIK3R1 PTP2C PTPN11 PXN SDGF SHPTP2 SRC SRC1 TGFA	Homo sapiens (human)
Mitochondrial Uncoupling	ADP/ATP translocase 1 Mitochondrial brown fat uncoupling protein 1	P12235 P25874	AAC1 ANT1 SLC25A4 SLC25A7 UCP UCP1	Homo sapiens (human)
SUMOylation of SUMOylation proteins	Aladin E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase Topors Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 mRNA export factor RAE1	A8CG34 O15504 O75694 P12270 P35658 P37198 P49790 P49792 P55735 P57740 P61956 P63165 P63279 P78406 Q12769 Q5SRE5 Q7Z3B4 Q8N1F7 Q8N2W9 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9NS56 Q9UKX7	AAAS ADRACALA C7orf14 CAIN CAN CG1 D3S1231E KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 LUN MP44 MRNP41 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 PIAS4 PIASG POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R SMT3B SMT3C SMT3H2 SMT3H3 SUMO1 SUMO2 TMEM48 TOPORS TP53BPL TPR UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
RAF activation	14-3-3 protein beta/alpha BRCA1-associated protein Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 GTPase HRas GTPase NRas Kinase suppressor of Ras 1 Leucine-rich repeat protein SHOC-2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase kinase kinase 11 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras-related protein M-Ras Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Tyrosine-protein kinase JAK2	O14807 O60674 P01111 P01112 P04049 P0DP23 P10398 P12931 P15056 P27448 P30153 P30154 P31946 P35232 P36507 P36873 P62140 P62714 P67775 Q02750 Q13362 Q13554 Q13555 Q13557 Q14738 Q15172 Q15173 Q16537 Q16584 Q7Z569 Q8IVT5 Q9UQ13 Q9UQM7	ARAF ARAF1 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CTAK1 EMK2 HRAS HRAS1 JAK2 KIAA0044 KIAA0862 KIAA0968 KSR KSR1 MAP2K1 MAP2K2 MAP3K11 MARK3 MEK1 MEK2 MKK2 MLK3 MRAS NRAS PHB PHB1 PKS PKS2 PPP1CB PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RNF52 RRAS3 SHOC2 SPRK SRC SRC1 YWHAB	Homo sapiens (human)
Integration of provirus	Barrier-to-autointegration factor Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y Importin subunit alpha-5 PC4 and SFRS1-interacting protein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	O75475 O75531 P04585 P04591 P04618 P05919 P17096 P52294 P62937 P69723 P69726	BAF BANF1 BCRG1 CYPA DFS70 HMGA1 HMGIY KPNA1 LEDGF PPIA PSIP1 PSIP2 RCH2 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Epithelial-Mesenchymal Transition (EMT) during gastrulation	Eomesodermin homolog Fibroblast growth factor receptor 1 T-box transcription factor T Zinc finger protein SNAI1	O15178 O95863 O95936 P11362	BFGFR CEK EOMES FGFBR FGFR1 FLG FLT2 HBGFR SNAH SNAI1 T TBR2 TBXT	Homo sapiens (human)
Signaling by PDGFRA extracellular domain mutants	GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1	O00459 P01111 P01112 P16234 P27986 P40763 P42224 P42336 P42338 Q07889	APRF GRB1 HRAS HRAS1 NRAS PDGFR2 PDGFRA PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 RHEPDGFRA SOS1 STAT1 STAT3	Homo sapiens (human)
Defective SLC7A9 causes cystinuria (CSNU)	Amino acid transporter heavy chain SLC3A1 b(0,+)-type amino acid transporter 1	P82251 Q07837	BAT1 NBAT SLC3A1 SLC7A9	Homo sapiens (human)
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK and LTK ligand 1 ALK and LTK ligand 2 ALK tyrosine kinase receptor Fibroblast growth factor receptor substrate 2 Insulin receptor substrate 1 Midkine Myc proto-oncogene protein N-myc proto-oncogene protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Pleiotrophin Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK3 Tyrosine-protein phosphatase non-receptor type 6	O00459 P01106 P04198 P19174 P21246 P21741 P27986 P29350 P35568 P40763 P42336 P42338 P52333 Q6UX46 Q6UXT8 Q8WU20 Q9UM73	ALK ALKAL1 ALKAL2 APRF BHLHE37 BHLHE39 FAM150A FAM150B FRS2 GRB1 HBNF1 HCP IRS1 JAK3 MDK MK1 MYC MYCN NEGF1 NEGF2 NMYC PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTN PTP1C PTPN6 STAT3	Homo sapiens (human)
Maturation of protein 3a	Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 ORF3a protein Polypeptide N-acetylgalactosaminyltransferase 1	P0DTC3 P15907 Q10472 Q11201 Q11203 Q11206 Q16842 Q8NDV1 Q9H4F1 Q9UJ37	3a CGS23 GALNT1 NANTA3 SIAT1 SIAT3C SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SIAT7B SIAT7C SIAT7D SIATL1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST6GAL1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 STHM STZ	Homo sapiens (human)
Chylomicron remodeling	Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 Lipoprotein lipase	P02647 P02649 P02652 P02655 P02656 P04114 P06727 P06858 Q6Q788 Q8IV16	APC2 APOA1 APOA2 APOA4 APOA5 APOB APOC2 APOC3 APOE GPIHBP1 HBP1 LIPD LPL RAP3	Homo sapiens (human)
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)	Sodium-dependent dopamine transporter	Q01959	DAT1 SLC6A3	Homo sapiens (human)
Regulation of RUNX1 Expression and Activity	Core-binding factor subunit beta Cyclin-dependent kinase 6 G1/S-specific cyclin-D1 G1/S-specific cyclin-D2 G1/S-specific cyclin-D3 Helicase MOV-10 Protein PML Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Proto-oncogene tyrosine-protein kinase Src Runt-related transcription factor 1 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Tyrosine-protein phosphatase non-receptor type 11	P12931 P24385 P29590 P30279 P30281 Q00534 Q01196 Q06124 Q13951 Q8NDV7 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9	AGO1 AGO2 AGO3 AGO4 AML1 BCL1 CAGH26 CBFA2 CBFB CCND1 CCND2 CCND3 CDK6 CDKN6 EIF2C1 EIF2C2 EIF2C3 EIF2C4 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 MOV10 MYL PML PP8675 PRAD1 PTP2C PTPN11 RNF71 RUNX1 SHPTP2 SRC SRC1 TNRC6 TNRC6A TNRC6B TNRC6C TRIM19	Homo sapiens (human)
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O60825 P16118 P17612 P22612 P22694 P30153 P30154 P62714 P67775 Q14738 Q16875 Q16877	F6PK PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFRX PKACA PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D PRKACA PRKACB PRKACG	Homo sapiens (human)
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)	Sodium- and chloride-dependent transporter XTRP3	Q9NP91	SIT1 SLC6A20 XT3 XTRP3	Homo sapiens (human)
Serotonin and melatonin biosynthesis	Acetylserotonin O-methyltransferase Aromatic-L-amino-acid decarboxylase Serotonin N-acetyltransferase Tryptophan 5-hydroxylase 1 Tryptophan 5-hydroxylase 2	P17752 P20711 P46597 Q16613 Q8IWU9	AADC AANAT ASMT DDC NTPH SNAT TPH TPH1 TPH2 TPRH TRPH	Homo sapiens (human)
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Acetylcholine receptor subunit alpha Neuronal acetylcholine receptor subunit alpha-2 Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit alpha-5 Neuronal acetylcholine receptor subunit alpha-6 Neuronal acetylcholine receptor subunit alpha-7 Neuronal acetylcholine receptor subunit alpha-9 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-3 Neuronal acetylcholine receptor subunit beta-4	P02708 P17787 P30532 P30926 P32297 P36544 P43681 Q05901 Q15822 Q15825 Q9UGM1	ACHRA CHNRA CHRNA1 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNA7 CHRNA9 CHRNB2 CHRNB3 CHRNB4 NACHRA3 NACHRA5 NACHRA7 NACHRA9 NACRA4	Homo sapiens (human)

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