GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	February 28, 2024
DisGeNET	February 14, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID	Disease Name	Gene Symbol ▲	Gene ID
DOID:5603	T-cell acute lymphoblastic leukemia	ABCC1 AKR1C3 CNTN2 GGH HPSE2 NUP145 PIK3CA PIK3CB PIK3CD PIK3CG PLA2R1 SOAT1	22925 4363 5290 5291 5293 5294 60495 6646 6900 852788 8644 8836
DOID:0112168	autosomal dominant nonsyndromic deafness 77	ABCC1 Abcc1 Abcc1	17250 24565 4363
DOID:9953	acute biphenotypic leukemia	ABCC1 GGH HPSE2 PLA2R1 SOAT1	22925 4363 60495 6646 8836
DOID:12603	acute leukemia	ABCC1 GGH HPSE2 PLA2R1 SOAT1	22925 4363 60495 6646 8836
DOID:10588	adrenoleukodystrophy	ABCD1 ABCD2 ABCD3 ACSBG1 ACSBG2 Abcd1 Abcd1 Abcd2 Abcd2 Abcd3 Abcd3 ELOVL1 ELOVL7 abcd1	11666 19299 215 225 23205 25270 26874 363516 566367 5825 64834 79993 81616 84356
DOID:905	Zellweger syndrome	ABCD3 Abcd3 Abcd3 PEX1 PEX1 Pex1 SCP2	19299 25270 5189 5825 6342 71382 853636
DOID:0111066	congenital bile acid synthesis defect 5	ABCD3 Abcd3 Abcd3	19299 25270 5825
DOID:684	hepatocellular carcinoma	ABCE1 ACE ACER3 ACTB ADE4 AKR1B1 ALDH2 ALDH7A1 ALDOC APRT APT1 APT2 ARG1 Abce1 Acer3 Aprt Aprt Aprt Arg1 Arg1 CAD CALR CAR1 CAT CDH13 CYP2C19 CYP2E1 Cad Calr Ces1f ERN1 Ern1 FHIT FUT6 Fhit Fhit G6PC1 G6PD G6pc1 G6pc1 GAPDH GGT1 GPC1 GPC3 GPX1 GPX3 HDAC1 HDAC1 HDAC2 HDAC4 HDAC5 HJV HK2 HMGCS2 HNT2 HPGDS HPRT1 HRAS HSPA5 Hdac2 Hdac4 Hdac4 Hprt1 Hprt1 Hras Hras ICAM1 IDH2 IGF2R IL18R1 INSR IRE1 Il18r1 KLRK1 KRAS Kras Kras Lerp MBL2 MEST MRC1 MTHFD2 Mthfd2 NEIL3 NRAS Neil3 Nmdmc Nras OGT PAFAH1B1 PIK3CA PIK3CB PLAAT4 PLAUR PLC1 PLCG1 PLOD3 PNPLA3 PON1 PPAT PRKAA2 PTEN PTGS2 Plcg1 Plcg1 Plod3 Plod3 Plod Pnpla3 PolG1 Pon1 Pon1 Ppat Ppat Prat R09H10.3 RAC1 RGN RIT1 RPD3 Rac1 Rac1 Ras85D Rgn Rgn Rit1 Rrp1 SMC3 SMC3 SMC3 SOAT2 SRD5A2 SULF1 TEP1 TIGAR YDC1 YPC1 ZK697.8 aprt-1 atgl-1 daf-2 dally dlp hda-1 hda-4 ire-1 neil3.L nras.L plc-3 plod3.L plod3 plod3 pyr-1 r rgn rgn	10014 100380996 1012 10797 116939 117544 11821 11846 14198 14377 148738 15182 15452 15461 1557 1571 16182 1636 16653 172232 174305 174385 174586 175410 175910 17768 179959 181723 187757 18803 18979 191414 19353 19733 19769 2081 208727 217 2272 22914 230 231 231327 23213 234258 234564 24015 24465 24525 24605 25106 2528 2538 2539 25634 25738 2597 26433 2678 2719 27306 2817 2876 2878 288583 292072 29221 293621 3065 3066 3099 3158 3251 32627 32640 3265 3309 33500 3383 3418 34792 3482 353 363287 363875 3643 380138 383 3845 38565 39013 39265 39596 399446 403070 40935 41140 41166 4153 4232 43223 4360 448549 47895 48224 4893 501 5048 5290 5291 5329 5335 5444 5471 55247 55331 556077 5563 57103 5728 5743 5879 5920 60 6016 60398 6059 66190 6716 69719 734090 78943 790 80339 811 84024 8435 847 8473 851899 852051 852481 853371 854986 855346 855386 855595 855860 855993 856018 856478 8809 8985 9104 9126 9759
DOID:526	human immunodeficiency virus infectious disease	ABCE1 AICDA Abce1 Aicda CD209 CYP2B6 MBL2 PLA2G2A PLAUR PTGS2 Pla2g2a Pla2g2a SAMHD1 SELP	11628 1555 18780 24015 25939 29692 30835 4153 5320 5329 57379 5743 6059 6403
DOID:3910	lung adenocarcinoma	ABCE1 AKR1A1 Abce1 CALR CD44 CLEC14A CYP24A1 Calr EEF2 EFT1 Eef2 Eef2 GPX3 HRAS IDH1 IDH2 IGF2R KRAS Kras Kras Lerp N PLC1 PLCG1 Plcg1 Plcg1 Plod Ras85D SAMHD1 SDC1 SULF2 Sdc eEF2 eef2.1.L eef2b plc-3	10327 13629 1591 161198 16653 174586 18803 1938 24015 24525 25738 25939 2878 29565 31293 3265 326929 3417 3418 3482 35422 37447 380348 3845 39265 41140 41166 43223 5335 55959 6059 6382 811 851993 855860 960