GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **376 - 400** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
FOXO-mediated transcription of cell death genes	B-cell lymphoma 6 protein Bcl-2-binding component 3, isoforms 1/2 Bcl-2-like protein 11 CREB-binding protein Cbp/p300-interacting transactivator 2 DNA damage-inducible transcript 3 protein Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Histone acetyltransferase p300 Nuclear transcription factor Y subunit alpha Nuclear transcription factor Y subunit beta Nuclear transcription factor Y subunit gamma Serine/threonine-protein kinase PINK1, mitochondrial Serine/threonine-protein kinase STK11 Tumor necrosis factor ligand superfamily member 6	O43521 O43524 P23511 P25208 P35638 P41182 P48023 P98177 Q09472 Q12778 Q13952 Q15831 Q92793 Q99967 Q9BXH1 Q9BXM7	AFX AFX1 APT1LG1 BBC3 BCL2L11 BCL5 BCL6 BIM CBP CD95L CHOP CHOP10 CITED2 CREBBP DDIT3 EP300 FASL FASLG FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 GADD153 HAP3 LAZ3 LKB1 MLLT7 MRG1 NFYA NFYB NFYC P300 PINK1 PJS PUMA STK11 TNFSF6 ZBTB27 ZNF51	Homo sapiens (human)
Acyl chain remodeling of DAG and TAG	1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 Acyl-CoA wax alcohol acyltransferase 2 Diacylglycerol O-acyltransferase 1 Diacylglycerol O-acyltransferase 2-like protein 6 Diacylglycerol O-acyltransferase 2 Monoglyceride lipase Patatin-like phospholipase domain-containing protein 2	O75907 Q6E213 Q6ZPD8 Q96AD5 Q96PD7 Q99685 Q9NST1	ADPN AGRP1 ATGL AWAT2 C22orf20 DC3 DC4 DGAT DGAT1 DGAT2 DGAT2L4 DGAT2L6 MFAT MGLL PNPLA2 PNPLA3 WS	Homo sapiens (human)
Formation of intermediate mesoderm	Bone morphogenetic protein 4 Fibroblast growth factor 2 Forkhead box protein C1 Forkhead box protein C2 LIM/homeobox protein Lhx1 Paired box protein Pax-2 Paired box protein Pax-8 Protein odd-skipped-related 1	P09038 P12644 P48742 Q02962 Q06710 Q12948 Q8TAX0 Q99958	BMP2B BMP4 DVR4 FGF2 FGFB FKHL14 FKHL7 FOXC1 FOXC2 FREAC3 LHX1 LIM-1 LIM1 MFH1 ODD OSR1 PAX2 PAX8	Homo sapiens (human)
Transport of the SLBP Dependant Mature mRNA	Aladin E3 SUMO-protein ligase RanBP2 Eukaryotic translation initiation factor 4E Histone RNA hairpin-binding protein Nuclear RNA export factor 1 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Protein SEC13 homolog THO complex subunit 4 mRNA export factor RAE1	A8CG34 O15504 O75694 P06730 P12270 P35658 P37198 P49790 P49792 P52298 P55735 P57740 P78406 Q09161 Q12769 Q14493 Q5SRE5 Q7Z3B4 Q86V81 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UBU9 Q9UKX7	AAAS ADRACALA ALY ALYREF BEF C7orf14 CAIN CAN CBP20 CBP80 CG1 D3S1231E EIF4E EIF4EL1 EIF4F HBP KIAA0023 KIAA0095 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 MP44 MRNP41 NCBP NCBP1 NCBP2 NDC1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 NXF1 PCNT1 POM121 POM121A POM121C RAE1 RANBP2 SEC13 SEC13A SEC13L1 SEC13R SLBP TAP THOC4 TMEM48 TPR	Homo sapiens (human)
Suppression of apoptosis	Apoptosis inhibitor Rv3654c Apoptosis inhibitor Rv3655c Cathepsin G E3 ubiquitin-protein ligase RNF213 Glycogen synthase kinase-3 alpha Low molecular weight protein-tyrosine phosphatase A Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Possible Mce-family lipoprotein LprM (Mce-family lipoprotein Mce3E) Serine protease inhibitor Rv3364c Splicing factor, proline- and glutamine-rich Zinc finger protein RFP	O50393 O53971 O69622 O69623 P08311 P14373 P23246 P27361 P28482 P49840 P9WIA1 Q63HN8	ALO17 C17orf27 CTSG ERK1 ERK2 GSK3A KIAA1554 KIAA1618 MAPK1 MAPK3 MYSTR PRKM1 PRKM2 PRKM3 PSF RFP RNF213 RNF76 Rv3364c Rv3654c Rv3655c SFPQ TRIM27 lprM mce3E mptpA ptpA	Homo sapiens (human)
Regulation of PTEN gene transcription	Atrophin-1 Cellular tumor antigen p53 Chromobox protein homolog 2 Chromobox protein homolog 6 Chromobox protein homolog 8 Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein 4 Cyclic AMP-dependent transcription factor ATF-2 E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Early growth response protein 1 GTP-binding protein Rheb Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 5 Histone deacetylase 7 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Histone-lysine N-methyltransferase EZH2 Histone-lysine N-methyltransferase MECOM Lysine-specific histone demethylase 1A Metastasis-associated protein MTA1 Metastasis-associated protein MTA2 Metastasis-associated protein MTA3 Methyl-CpG-binding domain protein 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neutral amino acid transporter 9 Nuclear receptor subfamily 2 group E member 1 Peroxisome proliferator-activated receptor gamma Polycomb complex protein BMI-1 Polycomb protein EED Polycomb protein SUZ12 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 RE1-silencing transcription factor REST corepressor 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein A Ras-related GTP-binding protein B Ras-related GTP-binding protein C Ras-related GTP-binding protein D Regulatory-associated protein of mTOR Repressor of RNA polymerase III transcription MAF1 homolog Sal-like protein 4 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Transcription factor Jun Transcriptional repressor p66-alpha Transcriptional repressor p66-beta Zinc finger protein SNAI1 Zinc finger protein SNAI2	O00257 O15379 O43504 O43623 O60341 O75530 O94776 O95503 O95863 O95983 P04637 P05412 P15336 P18146 P27361 P28482 P35226 P37231 P42345 P54259 P78364 Q03112 Q06587 Q09028 Q0VGL1 Q12873 Q13127 Q13330 Q13547 Q14781 Q14839 Q15022 Q15382 Q15910 Q16576 Q5VZM2 Q6IAA8 Q7L523 Q86YP4 Q8IXK0 Q8N122 Q8NBW4 Q8NDX5 Q8WUI4 Q8WXI9 Q92769 Q99496 Q9BTC8 Q9BVC4 Q9H063 Q9HB90 Q9HC52 Q9NQL2 Q9UHA4 Q9UJQ4 Q9UKL0 Q9UQL6 Q9Y2Q5 Q9Y466	AOF2 ATF2 ATN1 BAP1 BMI1 C11orf59 C7orf59 CBX2 CBX4 CBX6 CBX8 CHD3 CHD4 CHET9 CREB2 CREBP1 D12S755E DING DRPLA EDR1 EDR2 EDR3 EED EGR1 ERK1 ERK2 EVI1 EZH2 FRAP FRAP1 FRAP2 GATAD2A GATAD2B GBL HBXIP HDAC1 HDAC2 HDAC3 HDAC5 HDAC7 HDAC7A HIPI3 JJAZ1 JUN KDM1 KDM1A KIAA0071 KIAA0160 KIAA0600 KIAA0601 KIAA1150 KIAA1266 KIAA1303 KMT6 KROX24 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LSD1 LST8 MAF1 MAP2K1IP1 MAPBPIP MAPK1 MAPK3 MAPKSP1 MBD3 MDS1 MECOM MLST8 MTA1 MTA1L1 MTA2 MTA3 MTOR NR1C3 NR2E1 NRSF P53 PC3 PCGF4 PDRO PH1 PH2 PH3 PHC1 PHC2 PHC3 PID PPARG PRDM3 PRKM1 PRKM2 PRKM3 RAFT1 RAPT1 RAPTOR RBAP46 RBAP48 RBBP4 RBBP7 RC1 RCOR RCOR1 REST RHEB RHEB2 RING1 RING1A RING1B RNF1 RNF2 RNF51 ROBLD3 RPD3L1 RPTOR RRAGA RRAGB RRAGC RRAGD SALL4 SLC38A9 SLUG SLUGH SNAH SNAI1 SNAI2 SUZ12 TLX TP53 URLC11 XBR XIP ZNF225 ZNF797	Homo sapiens (human)
Regulation of gene expression by Hypoxia-inducible Factor	Aryl hydrocarbon receptor nuclear translocator CREB-binding protein Carbonic anhydrase 9 Cbp/p300-interacting transactivator 2 Endothelial PAS domain-containing protein 1 Erythropoietin HIG1 domain family member 1A, mitochondrial Histone acetyltransferase p300 Hypoxia-inducible factor 1-alpha Vascular endothelial growth factor A, long form	P01588 P15692 P27540 Q09472 Q16665 Q16790 Q92793 Q99814 Q99967 Q9Y241	ARNT BHLHE2 BHLHE73 BHLHE78 CA9 CBP CITED2 CREBBP EP300 EPAS1 EPO G250 HIF1A HIF2A HIG1 HIGD1A MN MOP1 MOP2 MRG1 P300 PASD2 PASD8 VEGF VEGFA	Homo sapiens (human)
Transcriptional activation of mitochondrial biogenesis	3'-5' exoribonuclease HELZ2 5-aminolevulinate synthase, non-specific, mitochondrial ATP synthase subunit beta, mitochondrial Acetyl-coenzyme A synthetase, cytoplasmic CREB-binding protein CREB-regulated transcription coactivator 1 CREB-regulated transcription coactivator 2 CREB-regulated transcription coactivator 3 Calcium/calmodulin-dependent protein kinase type IV Calmodulin-1 Chromodomain-helicase-DNA-binding protein 9 Cyclic AMP-dependent transcription factor ATF-2 Cytochrome c DNA polymerase subunit gamma-2 DNA-directed RNA polymerase, mitochondrial Dimethyladenosine transferase 1, mitochondrial Dimethyladenosine transferase 2, mitochondrial F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 GA-binding protein alpha chain Glutamate dehydrogenase 1, mitochondrial Glutamate dehydrogenase 2, mitochondrial Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Host cell factor 1 Isocitrate dehydrogenase [NADP], mitochondrial Mediator of RNA polymerase II transcription subunit 1 Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D NAD-dependent protein deacetylase sirtuin-3, mitochondrial NAD-dependent protein deacylase sirtuin-5, mitochondrial NAD-dependent protein lipoamidase sirtuin-4, mitochondrial Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1 Nuclear respiratory factor 1 PGC-1 and ERR-induced regulator in muscle protein 1 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Single-stranded DNA-binding protein, mitochondrial Steroid hormone receptor ERR1 Superoxide dismutase [Mn], mitochondrial Transcription factor A, mitochondrial Transcription termination factor 1, mitochondrial Trimethylguanosine synthase Twinkle mtDNA helicase	O00411 O15379 O60907 O75376 P00367 P04179 P06576 P0DP23 P11474 P13196 P15336 P19793 P20393 P48735 P49448 P51610 P99999 Q00059 Q04837 Q06413 Q06546 Q07869 Q14686 Q14814 Q15596 Q15648 Q15788 Q16566 Q16656 Q3L8U1 Q53ET0 Q5SV97 Q5VV67 Q6STE5 Q6UUV7 Q6UUV9 Q86X55 Q86YN6 Q8WVM0 Q92793 Q96RR1 Q96RS0 Q99551 Q9BYK8 Q9BZK7 Q9H5Q4 Q9NR19 Q9NTG7 Q9NXA8 Q9UBK2 Q9UHN1 Q9Y6E7	ACAS2 ACSS2 AIB3 ALAS1 ALAS3 ALASH ARC205 ATF2 ATP5B ATP5F1B ATPMB ATPSB BAF60C BHLHE74 BHLHE75 C10orf2 C1orf170 CALM CALM1 CAM CAM1 CAMK CAMK-GR CAMK4 CAMKIV CARM1 CBP CHD9 CREB2 CREBBP CREBP1 CRSP1 CRSP200 CRTC1 CRTC2 CRTC3 CYC CYCS DRIP205 DRIP230 E4TF1A EAR1 ERR1 ESRL1 ESRRA GABPA GLUD GLUD1 GLUD2 GLUDP1 HCA137 HCF1 HCFC1 HDAC3 HELZ2 HFC1 HREV IDH2 IRA1 KIAA0181 KIAA0308 KIAA0595 KIAA0616 KIAA1047 KIAA1769 KISH2 LEM6 MECT1 MED1 MEF2C MEF2D MTERF MTERF1 MTPOLB NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NR1C1 NR1D1 NR2B1 NR3B1 NRF1 NS5ATP5 PBP PEO1 PERC PERM1 PGC1 PGC1A PGC1B PIMT POLG2 POLRMT PPAR PPARA PPARBP PPARGBP PPARGC1 PPARGC1A PPARGC1B PPRC1 PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SIR2L3 SIR2L4 SIR2L5 SIRT3 SIRT4 SIRT5 SMARCD3 SOD2 SRC1 SRC2 SSBP SSBP1 TBL1 TBL1X TBL1XR1 TBLR1 TCF6 TCF6L2 TFAM TFB1M TFB2M TGS1 THRAL TIF2 TORC1 TORC2 TORC3 TRAP220 TRBP TRIP2 TWNK WAMTP1	Homo sapiens (human)
SHC-mediated cascade:FGFR4	Beta-klotho Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 GTPase HRas GTPase NRas Son of sevenless homolog 1	O43320 O76093 O95750 P01111 P01112 P05230 P08620 P09038 P10767 P22455 P31371 Q07889 Q86Z14 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF9 FGFA FGFB FGFR4 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF JTK2 KLB KS3 NRAS SOS1 TKF	Homo sapiens (human)
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 5'-3' exonuclease PLD4 Calmodulin-1 Inositol polyphosphate 5-phosphatase OCRL Inositol-tetrakisphosphate 1-kinase Inositol-trisphosphate 3-kinase A Inositol-trisphosphate 3-kinase B Inositol-trisphosphate 3-kinase C Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Synaptojanin-1 Type II inositol 1,4,5-trisphosphate 5-phosphatase	O15357 O43426 O75038 P0DP23 P16885 P19174 P23677 P27987 P32019 P51178 P60484 Q00722 Q01968 Q01970 Q13572 Q15147 Q15735 Q4KWH8 Q86YW0 Q8N3E9 Q92835 Q96BZ4 Q96DU7 Q9BRC7 Q9NQ66 Q9P212	C14orf175 CALM CALM1 CAM CAM1 INPP5B INPP5D INPP5J INPPL1 IP3KC ITPK1 ITPKA ITPKB ITPKC KIAA0450 KIAA0581 KIAA0910 KIAA1069 KIAA1516 KIAA1964 MMAC1 OCRL OCRL1 OCRL2 PIB5PA PIPP PLC1 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE PLCE1 PLCG1 PLCG2 PLCH1 PLCH2 PLCL3 PLCL4 PLCZ1 PLD4 PPLC PTEN SHIP SHIP1 SHIP2 SYNJ1 TEP1	Homo sapiens (human)
PECAM1 interactions	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Integrin alpha-V Integrin beta-3 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Platelet endothelial cell adhesion molecule Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6	P05106 P06239 P06241 P06756 P07947 P07948 P16284 P19174 P29350 Q06124 Q92835	FYN GP3A HCP INPP5D ITGAV ITGB3 JTK8 LCK LYN MSK8 PECAM1 PLC1 PLCG1 PTP1C PTP2C PTPN11 PTPN6 SHIP SHIP1 SHPTP2 VNRA VTNR YES YES1	Homo sapiens (human)
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	O14944 P00533 P01133 P01135 P15514 P19174 P35070 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 PLC1 PLCG1 SDGF TGFA	Homo sapiens (human)
Nef mediated downregulation of CD28 cell surface expression	AP-2 complex subunit mu Protein Nef T-cell-specific surface glycoprotein CD28	P04601 P10747 Q96CW1	AP2M1 CD28 CLAPM1 KIAA0109 nef	Homo sapiens (human)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2a Adenosine receptor A2b Adenosine receptor A3	P0DMS8 P29274 P29275 P30542	ADORA1 ADORA2 ADORA2A ADORA2B ADORA3	Homo sapiens (human)
Maturation of hRSV A proteins	Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Exportin-1 Furin Fusion glycoprotein F0 Importin subunit beta-1 Matrix protein Non-structural protein 1 Non-structural protein 2 Nucleoprotein Phosphoprotein Protein M2-1 RNA-directed RNA polymerase L Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3	O14980 P03418 P03420 P03421 P04543 P04545 P09958 P0DOE7 P0DOE9 P19784 P28887 P36873 P61009 P62136 P62140 P67812 P67870 P68400 P70168 Q15005 Q9BY50 Q9Y6A9	1B 1C CK2A1 CK2A2 CK2N CRM1 CSNK2A1 CSNK2A2 CSNK2B F FUR FURIN G5A Impnb KIAA0102 Kpnb1 L M M2-1 N NS1 NS2 P PACE PCSK3 PPP1A PPP1CA PPP1CB PPP1CC SEC11A SEC11C SEC11L1 SEC11L3 SPC12 SPC18 SPC21 SPC22 SPC25 SPCS1 SPCS2 SPCS3 SPCS4A SPCS4C XPO1	Homo sapiens (human)
Ras activation upon Ca2+ influx through NMDA receptor	Alpha-actinin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 GTPase HRas GTPase NRas Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2D Leucine-rich repeat-containing protein 7 Neurofilament light polypeptide Ras-specific guanine nucleotide-releasing factor 1 Ras-specific guanine nucleotide-releasing factor 2	O14827 O15399 P01111 P01112 P07196 P0DP23 P35609 P78352 Q05586 Q12959 Q13224 Q13554 Q13555 Q13557 Q13972 Q15700 Q92796 Q96NW7 Q9UQM7	ACTN2 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CDC25 DLG1 DLG2 DLG3 DLG4 GNRP GRF1 GRF2 GRIN1 GRIN2B GRIN2D GluN2D HRAS HRAS1 KIAA0968 KIAA1232 KIAA1365 LAP1 LRRC7 NEFL NF68 NFL NMDAR1 NMDAR2B NMDAR2D NRAS PSD95 RASGRF1 RASGRF2	Homo sapiens (human)
Biosynthesis of DPAn-3-derived maresins	Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX12	P09917 P18054	12LO ALOX12 ALOX5 LOG12 LOG5	Homo sapiens (human)
RAC2 GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Abl interactor 1 Abl interactor 2 Actin remodeling regulator NHS Actin-binding protein WASF2 Active breakpoint cluster region-related protein Ankyrin repeat and LEM domain-containing protein 2 Armadillo repeat-containing X-linked protein 3 BAR/IMD domain-containing adapter protein 2-like 1 Breakpoint cluster region protein Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 4 Cell division control protein 42 homolog Cell surface glycoprotein MUC18 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein 1 DEP domain-containing protein 1B Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 1 Dedicator of cytokinesis protein 2 Dedicator of cytokinesis protein 3 Dedicator of cytokinesis protein 4 Delta(14)-sterol reductase LBR Desmoglein-2 Differentially expressed in FDCP 6 homolog Emerin Ephrin type-A receptor 2 Erbin Extended synaptotagmin-1 Granule associated Rac and RHOG effector protein 1 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Inner nuclear membrane protein Man1 Integrin beta-1 Lamina-associated polypeptide 2, isoforms beta/gamma MAGUK p55 subfamily member 7 Membrane-associated progesterone receptor component 2 Metaxin-1 Nck-associated protein 1-like Nck-associated protein 1 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Oligophrenin-1 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phospholipase D2 Protein BRICK1 Protein ERGIC-53 Protein diaphanous homolog 3 Proto-oncogene DBL Proto-oncogene vav Rac GTPase-activating protein 1 Ragulator complex protein LAMTOR1 Ras GTPase-activating-like protein IQGAP1 Ras-related C3 botulinum toxin substrate 2 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 21 Rho GTPase-activating protein 26 Rho GTPase-activating protein 32 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 42 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor TIAM1 SLIT and NTRK-like protein 5 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase TAO3 Serine/threonine-protein kinase VRK2 Sorting and assembly machinery component 50 homolog Starch-binding domain-containing protein 1 Switch-associated protein 70 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein 1 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B/C	A6NI28 A7KAX9 O00459 O14939 O15063 O15173 O60890 O75962 O94991 O95210 O95292 O96013 P02786 P04839 P05556 P10911 P11274 P13498 P14598 P15153 P15498 P19878 P27986 P29317 P42167 P42336 P43121 P46940 P49257 P50402 P51149 P52565 P52735 P55160 P60953 Q00587 Q03135 Q07960 Q12979 Q13009 Q13153 Q13177 Q13505 Q14126 Q14161 Q14185 Q14739 Q15080 Q15836 Q5T2T1 Q5T5U3 Q68EM7 Q6IAA8 Q6T4R5 Q6ZW31 Q7L576 Q86XL3 Q86Y07 Q8IZD9 Q8IZP0 Q8N1I0 Q8TAA9 Q8TCU6 Q8WUW1 Q8WUY9 Q92569 Q92608 Q96BY6 Q96RT1 Q9BSJ8 Q9C0H5 Q9H0H5 Q9H2K8 Q9H3Q1 Q9H4E7 Q9NRY4 Q9NSV4 Q9NYB9 Q9UH62 Q9UH65 Q9UHR4 Q9UKW4 Q9UNA1 Q9Y2A7 Q9Y2U8 Q9Y2X7 Q9Y512 Q9Y6W5	ABI1 ABI2 ABR ALEX3 ANKLE2 ARGBPIA ARHGAP1 ARHGAP10 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP42 ARHGDIA ARMCX3 BAIAP2L1 BCR BCR1 BORG4 BORG5 BRK1 C11orf59 C3orf10 CAV CAV1 CDC42 CDC42EP1 CDC42EP4 CDC42GAP CDHF5 CEP1 CEP4 CYBA CYBB CYFIP1 D22S11 DBL DEF6 DEPDC1B DG6 DIAP3 DIAPH3 DOCK1 DOCK10 DOCK2 DOCK3 DOCK4 DPK DSG2 ECK EDMD EMD EPHA2 ERBB2IP ERBIN ERGIC53 ESYT1 F5F8D FAM62A FNRB GARRE1 GDIA1 GIT1 GIT2 GRAF GRAF3 GRB1 GRF1 GRIT GRLF1 HEM1 HEM2 IBP IQGAP1 IRTKS ITGB1 JIK KDS KIAA0051 KIAA0068 KIAA0148 KIAA0209 KIAA0299 KIAA0355 KIAA0587 KIAA0621 KIAA0640 KIAA0692 KIAA0694 KIAA0712 KIAA0716 KIAA0747 KIAA0918 KIAA1142 KIAA1225 KIAA1415 KIAA1424 KIAA1478 KIAA1688 KIAA1722 LAMTOR1 LAP2 LBR LEM4 LEMD3 LMAN1 LRRC11 MAN1 MAP3K18 MBC2 MCAM MCF2 MDF2 MGCRACGAP MOCA MPP7 MSE55 MSK12 MTX MTX1 MTXN MUC18 NAP1 NCF1 NCF2 NCF4 NCKAP1 NCKAP1L NHS NOX2 NOXA2 NOXO2 OPHN1 OPHN1L P190A P67PHOX PAK1 PAK2 PAK4 PDRO PGRMC2 PIK3CA PIK3R1 PIK3R2 PIK3R3 PLD2 PMBP PREX1 RAB7 RAB7A RAC2 RACGAP1 RHOGAP1 RICH1 RICS SAM50 SAMM50 SH3PXD1A SH3PXD4 SLITRK5 SSH3BP1 STA STB2 STBD1 SWAP70 SYB3 SYDE1 TAOK3 TFRC TIAM1 TMEM133 TMPO TRIO VAMP3 VANGL1 VAPB VAV VAV1 VAV2 VAV3 VRK2 WASF2 WAVE2 XTP8 ZIZ3 p190ARHOGAP	Homo sapiens (human)
Activation of RAS in B cells	GTPase HRas GTPase NRas RAS guanyl-releasing protein 1 Ras guanyl-releasing protein 3	O95267 P01111 P01112 Q8IV61	GRP3 HRAS HRAS1 KIAA0846 NRAS RASGRP RASGRP1 RASGRP3	Homo sapiens (human)
Stimulation of the cell death response by PAK-2p34	Caspase-3 Serine/threonine-protein kinase PAK 2	P42574 Q13177	CASP3 CPP32 PAK2	Homo sapiens (human)
Sensory processing of sound by inner hair cells of the cochlea	Band 4.1-like protein 1 Band 4.1-like protein 3 Cadherin-23 Calcium and integrin-binding family member 2 Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Calcium-binding protein 1 Calcium-binding protein 2 Chloride intracellular channel protein 5 DnaJ homolog subfamily C member 5 Epidermal growth factor receptor kinase substrate 8-like protein 2 Epidermal growth factor receptor kinase substrate 8 Espin-like protein Espin Ezrin F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit beta Fascin-2 Glutaredoxin domain-containing cysteine-rich protein 1 Glutaredoxin domain-containing cysteine-rich protein 2 Harmonin LHFPL tetraspan subfamily member 5 protein Leucine-rich repeat-containing protein 52 Moesin Myosin-9 Myosin-IIIa Myosin-IIIb Otoferlin Pejvakin Peripheral plasma membrane protein CASK Plasma membrane calcium-transporting ATPase 1 Plastin-1 Potassium voltage-gated channel subfamily KQT member 4 Protein bassoon Protein piccolo Protocadherin-15 Radixin Ras-related protein Rab-3A Rho family-interacting cell polarization regulator 2 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Stereocilin Synapsin-1 Synaptophysin Synaptosomal-associated protein 25 Syntaxin-1A Taperin Transmembrane channel-like protein 1 Transmembrane channel-like protein 2 Transmembrane inner ear expressed protein Twinfilin-1 Twinfilin-2 Unconventional myosin-Ic Unconventional myosin-VIIa Unconventional myosin-XV Vesicle-associated membrane protein 2 Vesicular glutamate transporter 3 Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel subunit alpha-2/delta-2 Whirlin Xin actin-binding repeat-containing protein 2 pre-mRNA splicing regulator USH1G	A4UGR9 A6NFK2 A8MXD5 B1AK53 O00159 O14926 O14936 O75838 P08247 P15311 P17600 P20020 P20336 P26038 P35241 P35579 P47755 P47756 P52907 P56696 P60880 P63027 Q01082 Q01668 Q08289 Q0ZLH3 Q12791 Q12792 Q12929 Q13402 Q13813 Q14651 Q16558 Q16623 Q495M9 Q4KMQ1 Q6IBS0 Q6ZVH7 Q7RTU9 Q8N7C0 Q8NDX2 Q8NEV4 Q8NEW7 Q8TAF8 Q8TDI7 Q8TDI8 Q8WXR4 Q96QU1 Q9H251 Q9H3Z4 Q9H4G0 Q9H6S3 Q9HC10 Q9NPB3 Q9NY47 Q9NZA1 Q9NZU7 Q9P202 Q9UKN7 Q9UPA5 Q9Y2J2 Q9Y4F9 Q9Y6N9 Q9Y6V0	ACZ AIE75 ATP2B1 BSN C20orf145 C6orf32 C9orf75 CABP1 CABP2 CACH3 CACN4 CACNA1D CACNA2D2 CACNB2 CACNL1A2 CACNLB2 CAPZA1 CAPZA2 CAPZB CASK CCHL1A2 CDH23 CIB2 CLIC5 CLN4 CMYA3 DAL1 DFNB25 DFNB31 DFNB36 DFNB59 DIFF48 DNAJC5 EPB41L1 EPB41L3 EPS8 EPS8L2 EPS8R2 ESPN ESPNL EZR FAM65B FER1L2 FSCN2 GRXCR1 GRXCR2 KCNMA KCNMA1 KCNMB1 KCNQ4 KIAA0338 KIAA0386 KIAA0434 KIAA0558 KIAA0559 KIAA0987 KIAA1526 KIAA1774 KIAA1812 KIP2 LHFPL5 LIN2 LRRC52 MSN MYH9 MYO15 MYO15A MYO1C MYO3A MYO3B MYO7A MYSB NEAS OTOF PCDH15 PCLO PJVK PL48 PLS1 PMCA1 PTK9 PTK9L RAB3A RDX RIPOR2 SANS SLC17A8 SLO SNAP SNAP25 SPTA2 SPTAN1 SPTB2 SPTBN1 STRC STX1 STX1A SYB2 SYN1 SYP TMC1 TMC2 TMHS TMIE TPRN TWF1 TWF2 USH1B USH1C USH1F USH1G VAMP2 VGLUT3 VIL2 WHRN XIRP2 ZNF231	Homo sapiens (human)
Defective CYP11A1 causes AICSR	Adrenodoxin, mitochondrial Cholesterol side-chain cleavage enzyme, mitochondrial Ferredoxin-2, mitochondrial NADPH	P05108 P10109 P22570 Q6P4F2	ADX ADXR CYP11A CYP11A1 FDX1 FDX1L FDX2 FDXR	Homo sapiens (human)
RHO GTPases activate PAKs	Calmodulin-1 Cell division control protein 42 homolog Filamin-A LIM domain kinase 1 Merlin Myosin light chain kinase, smooth muscle Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit 12B Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Src substrate cortactin	O14950 O14974 O60237 O75914 P0DP23 P21333 P24844 P35240 P35579 P35580 P35749 P53667 P60660 P60953 P62140 P63000 Q13153 Q13177 Q14247 Q15746 Q7Z406	CALM CALM1 CAM CAM1 CDC42 CTTN EMS1 FLN FLN1 FLNA KIAA0866 KIAA2034 LIMK LIMK1 MBS MLC2 MLCK MLCK1 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYLK MYLK1 MYPT1 MYPT2 MYRL2 NF2 OPHN3 PAK1 PAK2 PAK3 PPP1CB PPP1R12A PPP1R12B RAC1 SCH TC25	Homo sapiens (human)
STAT5 activation downstream of FLT3 ITD mutants	Bcl-2-like protein 1 Cyclin-dependent kinase inhibitor 1 GRB2-associated-binding protein 2 Growth factor receptor-bound protein 2 NADPH oxidase 4 Receptor-type tyrosine-protein kinase FLT3 Serine/threonine-protein kinase pim-1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein phosphatase non-receptor type 11	P11309 P36888 P38936 P42229 P51692 P62993 Q06124 Q07817 Q9NPH5 Q9UQC2	ASH BCL2L BCL2L1 BCLX CAP20 CD135 CDKN1 CDKN1A CIP1 FLK2 FLT3 GAB2 GRB2 KIAA0571 MDA6 NOX4 PIC1 PIM1 PTP2C PTPN11 RENOX SDI1 SHPTP2 STAT5 STAT5A STAT5B STK1 WAF1	Homo sapiens (human)
Orc1 removal from chromatin	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cell division control protein 6 homolog Cullin-1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA helicase MCM8 DNA replication factor Cdt1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 E3 ubiquitin-protein ligase RBX1 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Origin recognition complex subunit 6 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 O43913 O43929 P0CG47 P0CG48 P17980 P20248 P20618 P24941 P25205 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P33991 P33992 P33993 P35998 P43686 P48556 P49720 P49721 P49736 P51665 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P63208 P78396 Q13200 Q13309 Q13415 Q13416 Q13616 Q14566 Q15008 Q16186 Q99436 Q99460 Q99741 Q9H211 Q9UBD5 Q9UJA3 Q9UNM6 Q9Y5N6	ADRM1 BM28 C20orf154 C7orf76 CCN1 CCNA CCNA1 CCNA2 CCNL1 CDC18L CDC21 CDC46 CDC47 CDC6 CDCL1 CDK2 CDKN2 CDT1 CUL1 DSS1 EMC19 FBXL1 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0030 KIAA0107 LATHEO LMPX LMPY MB1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MCM8 MIP224 MOV34L MSS1 NU OCP2 ORC1 ORC1L ORC2 ORC2L ORC3 ORC3L ORC4 ORC4L ORC5 ORC5L ORC6 ORC6L PARC1 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SKP2 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)

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