GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Influenza Virus Induced Apoptosis	ADP/ATP translocase 3 Neuraminidase Protein PB1-F2 Transforming growth factor beta-1 proprotein	P01137 P03468 P0C0U1 P12236	AAC3 ANT3 NA PB1 SLC25A6 TGFB TGFB1	Homo sapiens (human)
Synthesis of Ketone Bodies	3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic Acetoacetyl-CoA synthetase Acetyl-CoA acetyltransferase, mitochondrial Acyl-CoA synthetase short-chain family member 3, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Dehydrogenase/reductase SDR family member 6 Hydroxymethylglutaryl-CoA lyase, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial	P24752 P35914 P54868 Q02338 Q86V21 Q8TB92 Q9BUT1 Q9H6R3	AACS ACAT ACAT1 ACSF1 ACSS3 BDH BDH1 BDH2 DHRS6 HMGCL HMGCLL1 HMGCS2 MAT SDR15C1 SDR9C1	Homo sapiens (human)
Phase I - Functionalization of compounds	Aldehyde dehydrogenase, dimeric NADP-preferring Amine oxidase [copper-containing] 2 Amine oxidase [copper-containing] 3 Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Carbonyl reductase [NADPH] 3 Carboxylesterase 3 Carboxymethylenebutenolidase homolog Cocaine esterase Cytochrome P450 2B6 Cytochrome P450 3A4 Cytochrome b5 type B Diamine oxidase [copper-containing] Epoxide hydrolase 1 Liver carboxylesterase 1 Mitochondrial amidoxime reducing component 2 Mitochondrial amidoxime-reducing component 1 NADH-cytochrome b5 reductase 3 Ribosyldihydronicotinamide dehydrogenase [quinone] Valacyclovir hydrolase	A9YTQ3 O00748 O43169 O75106 O75828 P00387 P07099 P08684 P16083 P19801 P20813 P22760 P23141 P27540 P30838 P35869 Q16853 Q5VT66 Q6UWW8 Q86WA6 Q969Z3 Q96DG6 Q9HBZ2	AADAC ABP ABP1 AHR AHRR ALDH3 ALDH3A1 AOC1 AOC2 AOC3 ARNT ARNT2 BHLHE1 BHLHE2 BHLHE76 BHLHE77 BPHL CBR3 CES1 CES2 CES3 CMBL CYB5B CYB5M CYB5R3 CYP2B6 CYP3A3 CYP3A4 DAC DAO DIA1 EPHX EPHX1 EPOX ICE KIAA0307 KIAA1234 MARC1 MARC2 MCNAA MOSC1 MOSC2 MTARC1 MTARC2 NMOR2 NQO2 OMB5 SDR21C2 SES1 VAP1	Homo sapiens (human)
LDL clearance	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Apolipoprotein B-100 Carboxylesterase 3 Clathrin heavy chain 1 Clathrin light chain A Lipolysis-stimulated lipoprotein receptor Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor Lysosomal acid lipase/cholesteryl ester hydrolase NPC intracellular cholesterol transporter 1 NPC intracellular cholesterol transporter 2 Neutral cholesterol ester hydrolase 1 Proprotein convertase subtilisin/kexin type 9 Sterol O-acyltransferase 1 Sterol O-acyltransferase 2	O15118 O75908 O94973 O95782 P01130 P04114 P09496 P35610 P38571 P53680 P61916 P63010 Q00610 Q5SW96 Q6PIU2 Q6UWW8 Q86X29 Q8NBP7 Q96CW1	AADACL1 ACACT ACACT1 ACACT2 ACAT ACAT1 ACAT2 ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARH CES3 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 HE1 HIP9 HYPJ ILDR3 KIAA0034 KIAA0109 KIAA0899 KIAA1363 LDLR LDLRAP1 LIPA LISCH LSR NARC1 NCEH1 NPC1 NPC2 PCSK9 SOAT SOAT1 SOAT2 STAT	Homo sapiens (human)
Lysine catabolism	5-phosphohydroxy-L-lysine phospho-lyase Alpha-aminoadipic semialdehyde dehydrogenase Alpha-aminoadipic semialdehyde synthase, mitochondrial Glutaryl-CoA dehydrogenase, mitochondrial Hydroxylysine kinase Ketimine reductase mu-crystallin Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Mitochondrial 2-oxodicarboxylate carrier Peroxisomal sarcosine oxidase	A2RU49 P49419 Q14894 Q8IUZ5 Q8N5Z0 Q92947 Q9BQT8 Q9P0Z9 Q9UDR5	AADAT AASS AGPHD1 AGXT2L2 ALDH7A1 ATQ1 CRYM GCDH HYKK KAT2 KYAT2 LPIPOX ODC PHYKPL PIPOX PSO SLC25A21 THBP	Homo sapiens (human)
Tryptophan catabolism	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 3-hydroxyanthranilate 3,4-dioxygenase Amino acid transporter heavy chain SLC3A2 Indoleamine 2,3-dioxygenase 1 Indoleamine 2,3-dioxygenase 2 Kynureninase Kynurenine 3-monooxygenase Kynurenine formamidase Kynurenine--oxoglutarate transaminase 1 Kynurenine--oxoglutarate transaminase 3 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Large neutral amino acids transporter small subunit 1 Neutral amino acid uniporter 4 Tryptophan 2,3-dioxygenase	O15229 P08195 P14902 P46952 P48775 Q01650 Q16719 Q16773 Q63HM1 Q6YBV0 Q6YP21 Q6ZQW0 Q8N5Z0 Q8TDX5	AADAT ACMSD AFMID CCBL1 CCBL2 CD98LC HAAO IDO IDO1 IDO2 INDO INDOL1 KAT2 KAT3 KMO KYAT1 KYAT2 KYAT3 KYNU LAT1 MDU1 MPE16 PAT4 SLC36A4 SLC3A2 SLC7A5 TDO TDO2	Homo sapiens (human)
Serotonin and melatonin biosynthesis	Acetylserotonin O-methyltransferase Aromatic-L-amino-acid decarboxylase Serotonin N-acetyltransferase Tryptophan 5-hydroxylase 1 Tryptophan 5-hydroxylase 2	P17752 P20711 P46597 Q16613 Q8IWU9	AADC AANAT ASMT DDC NTPH SNAT TPH TPH1 TPH2 TPRH TRPH	Homo sapiens (human)
Catecholamine biosynthesis	Aromatic-L-amino-acid decarboxylase Dopamine beta-hydroxylase Phenylethanolamine N-methyltransferase Tyrosine 3-monooxygenase	P07101 P09172 P11086 P20711	AADC DBH DDC PENT PNMT TH TYH	Homo sapiens (human)
Recognition and association of DNA glycosylase with site containing an affected purine	Adrenocortical dysplasia protein homolog DNA-3-methyladenine glycosylase Endonuclease 8-like 3 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O15527 O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P29372 P33778 P54274 P57053 P58876 P62805 P62807 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q8TAT5 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0	AAG ACD ANPG DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 MID1 MMH MPG MUTM NEIL3 OGG1 OGH1 PIN2 PIP1 POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B	Homo sapiens (human)
Cleavage of the damaged purine	Adrenocortical dysplasia protein homolog DNA-3-methyladenine glycosylase Endonuclease 8-like 3 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O15527 O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P29372 P33778 P54274 P57053 P58876 P62805 P62807 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q8TAT5 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0	AAG ACD ANPG DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 MID1 MMH MPG MUTM NEIL3 OGG1 OGH1 PIN2 PIP1 POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B	Homo sapiens (human)
Displacement of DNA glycosylase by APEX1	DNA repair nuclease/redox regulator APEX1 DNA-3-methyladenine glycosylase Endonuclease III-like protein 1 G/T mismatch-specific thymine DNA glycosylase Methyl-CpG-binding domain protein 4 N-glycosylase/DNA lyase Single-strand selective monofunctional uracil DNA glycosylase	O15527 O95243 P27695 P29372 P78549 Q13569 Q53HV7	AAG ANPG APE APE1 APEX APEX1 APX HAP1 MBD4 MED1 MID1 MMH MPG MUTM NTH1 NTHL1 OCTS3 OGG1 OGH1 REF1 SMUG1 TDG	Homo sapiens (human)
Clathrin-mediated endocytosis	ADP-ribosylation factor 6 ADP-ribosylation factor GTPase-activating protein 1 AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma AP2-associated protein kinase 1 Actin nucleation-promoting factor WASL Actin-related protein 2/3 complex subunit 1A Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Adaptin ear-binding coat-associated protein 1 Adaptin ear-binding coat-associated protein 2 Amphiphysin Amphiregulin Apolipoprotein B-100 Arf-GAP domain and FG repeat-containing protein 1 Auxilin Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Cdc42-interacting protein 4 Clathrin coat assembly protein AP180 Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Cyclin-G-associated kinase Cystic fibrosis transmembrane conductance regulator Disabled homolog 2 Dynamin-1 Dynamin-2 Dynamin-3 Dyslexia-associated protein KIAA0319 E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15-like 1 Epidermal growth factor receptor substrate 15 Epidermal growth factor receptor Epigen Epsin-1 Epsin-2 F-BAR domain only protein 1 F-BAR domain only protein 2 Formin-binding protein 1-like Formin-binding protein 1 Frizzled-4 GTPase-activating protein and VPS9 domain-containing protein 1 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate Huntingtin-interacting protein 1-related protein Huntingtin-interacting protein 1 Inositol polyphosphate 5-phosphatase OCRL Interleukin-7 receptor subunit alpha Intersectin-1 Intersectin-2 Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Low-density lipoprotein receptor Lysosome membrane protein 2 Muscarinic acetylcholine receptor M2 Myc box-dependent-interacting protein 1 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol-binding clathrin assembly protein Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein Wnt-5a Protein kinase C and casein kinase substrate in neurons protein 1 Protein kinase C and casein kinase substrate in neurons protein 2 Protein kinase C and casein kinase substrate in neurons protein 3 Protransforming growth factor alpha RalBP1-associated Eps domain-containing protein 1 RalBP1-associated Eps domain-containing protein 2 Ras-related protein Rab-5A Ras-related protein Rab-5B Ras-related protein Rab-5C SH3 domain-containing kinase-binding protein 1 SH3-containing GRB2-like protein 3-interacting protein 1 Segment polarity protein dishevelled homolog DVL-2 Serotransferrin Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Solute carrier family 2, facilitated glucose transporter member 8 Sorting nexin-18 Sorting nexin-9 Src substrate cortactin Stonin-1 Stonin-2 Substance-P receptor Synaptojanin-1 Synaptojanin-2 Synaptotagmin-11 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-8 Synaptotagmin-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Trans-Golgi network integral membrane protein 2 Transferrin receptor protein 1 Type-1 angiotensin II receptor Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 Vesicular acetylcholine transporter	O00291 O00401 O00443 O00499 O14526 O14641 O14944 O14964 O14976 O15056 O15144 O15145 O15511 O43426 O43493 O60331 O60641 O75061 O75146 O75379 O75886 O94973 O95208 O95782 P00533 P01130 P01133 P01135 P01185 P01730 P02786 P02787 P04114 P04234 P07550 P08172 P09496 P09497 P09693 P0CG47 P0CG48 P11142 P11717 P13569 P15514 P16871 P20339 P20645 P21579 P22681 P25103 P30518 P30556 P32121 P35070 P41221 P42566 P49407 P49418 P50570 P51148 P51809 P52594 P53675 P53680 P59998 P61020 P61158 P61160 P62330 P62979 P62987 P63010 P63027 P98082 P98164 Q00610 Q01968 Q05193 Q0JRZ9 Q13492 Q14108 Q14247 Q14C86 Q15642 Q15811 Q15836 Q16572 Q2M2I8 Q5SW96 Q5T0N5 Q5VV43 Q6UW88 Q86SS6 Q8N6T3 Q8N9I0 Q8NBV8 Q8NC96 Q8NFH8 Q8WXE9 Q92747 Q92783 Q96B97 Q96CW1 Q96D71 Q96RF0 Q96RU3 Q99075 Q99961 Q99962 Q99963 Q9BQI5 Q9BT88 Q9BV40 Q9BY11 Q9NVZ3 Q9NY64 Q9NZM3 Q9UBC2 Q9UKS6 Q9ULV1 Q9UNF0 Q9UQ16 Q9Y5X1 Q9Y6I3 Q9Y6Q2	AAK1 ABCC7 ACTR2 ACTR3 ADHR ADRB2 ADRB2R ADTAA ADTAB ADTB2 AF1P AGFG1 AGTR1 AGTR1A AGTR1B AMPH AMPH1 AMPHL AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARB2 ARC16 ARC20 ARC21 ARC34 AREG AREGB ARF1GAP ARF6 ARFGAP1 ARH ARP2 ARP3 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ARR1 ARR2 ARRB1 ARRB2 ARVP AT2R1 AT2R1B AVP AVPR2 B2AR BIN1 BTC C1orf39 CALM CBL CBL2 CD36L2 CD3D CD3G CD4 CFTR CHRM2 CIN85 CIP4 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD CNSA1 CNSA2 CNSA3 CTTN DAB2 DIR DIR3 DNAJC26 DNAJC6 DNM DNM1 DNM2 DNM3 DOC2 DTR DTS DVL2 DYN2 EGF EGFR EMS1 EPGN EPN1 EPN2 EPS15 EPS15L1 EPS15R ERBB ERBB1 EREG FBP17 FCHO1 FCHO2 FNBP1 FNBP1L FZD4 GAK GAPEX5 GAPVD1 GLUT8 GLUTX1 HBEGF HBP HEGFL HER1 HGS HIP1 HIP12 HIP1R HIP9 HRB HRS HSC70 HSP73 HSPA10 HSPA8 HYPJ IGF2R IL7R ITSN ITSN1 ITSN2 KIAA0034 KIAA0080 KIAA0109 KIAA0290 KIAA0319 KIAA0348 KIAA0473 KIAA0554 KIAA0589 KIAA0655 KIAA0656 KIAA0820 KIAA0899 KIAA0910 KIAA1048 KIAA1065 KIAA1256 KIAA1379 KIAA1521 LDLR LDLRAP1 LIMP2 LIMPII LRP2 M6PR MPR46 MPRD MPRI NECAP1 NECAP2 NK1R OCRL OCRL1 PACSIN1 PACSIN2 PACSIN3 PICALM PIK3C2A PIP5K1C POB1 RAB RAB5 RAB5A RAB5B RAB5C RABL RAP6 REPS1 REPS2 RIP RNF55 RPS27A SALF SBLF SCARB2 SDGF SGIP1 SH3D1A SH3D1B SH3D2A SH3D2B SH3D2C SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SH3PX1 SH3PXD3A SH3PXD3B SLC18A3 SLC2A8 SNAP91 SNX18 SNX9 SOP2L STAM STAM1 STAM2 STN1 STN2 STNB STON1 STON2 STOT STP SVP65 SWAP SYB2 SYB3 SYBL1 SYNJ1 SYNJ2 SYT SYT1 SYT11 SYT2 SYT8 SYT9 T3D T3G TAC1R TACR1 TF TFRC TGFA TGN46 TGN51 TGOLN2 TOCA1 TRIP10 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 V2R VACHT VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VP WASL WNT5A	Homo sapiens (human)
Cargo recognition for clathrin-mediated endocytosis	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma AP2-associated protein kinase 1 Adaptin ear-binding coat-associated protein 1 Adaptin ear-binding coat-associated protein 2 Amphiregulin Apolipoprotein B-100 Arf-GAP domain and FG repeat-containing protein 1 Beta-2 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7a COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 8 Cation-dependent mannose-6-phosphate receptor Cation-independent mannose-6-phosphate receptor Clathrin coat assembly protein AP180 Clathrin heavy chain 1 Clathrin heavy chain 2 Clathrin light chain A Clathrin light chain B Cystic fibrosis transmembrane conductance regulator Disabled homolog 2 Dyslexia-associated protein KIAA0319 E3 ubiquitin-protein ligase CBL Endophilin-A1 Endophilin-A2 Endophilin-A3 Epidermal growth factor receptor substrate 15-like 1 Epidermal growth factor receptor substrate 15 Epidermal growth factor receptor Epigen Epsin-1 Epsin-2 F-BAR domain only protein 1 F-BAR domain only protein 2 Frizzled-4 G protein-coupled receptor kinase 3 Hepatocyte growth factor-regulated tyrosine kinase substrate Interleukin-7 receptor subunit alpha Intersectin-1 Intersectin-2 Low density lipoprotein receptor adapter protein 1 Low-density lipoprotein receptor-related protein 2 Low-density lipoprotein receptor Lysosome membrane protein 2 Muscarinic acetylcholine receptor M2 NEDD8 Phosphatidylinositol-binding clathrin assembly protein Polyubiquitin-B Polyubiquitin-C Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein Wnt-5a Protransforming growth factor alpha RalBP1-associated Eps domain-containing protein 1 RalBP1-associated Eps domain-containing protein 2 SH3 domain-containing kinase-binding protein 1 SH3-containing GRB2-like protein 3-interacting protein 1 Segment polarity protein dishevelled homolog DVL-2 Serotransferrin Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Solute carrier family 2, facilitated glucose transporter member 8 Stonin-1 Stonin-2 Substance-P receptor Synaptotagmin-11 Synaptotagmin-1 Synaptotagmin-2 Synaptotagmin-8 Synaptotagmin-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Torsin-1A Torsin-1B Trans-Golgi network integral membrane protein 2 Transferrin receptor protein 1 Type-1 angiotensin II receptor Ubiquilin-1 Ubiquilin-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 4 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 Vesicular acetylcholine transporter	O14526 O14641 O14656 O14657 O14944 O14964 O43493 O60641 O75379 O75886 O94973 O95208 O95782 P00533 P01130 P01133 P01135 P01185 P01730 P02786 P02787 P04114 P04234 P07550 P08172 P09496 P09497 P09693 P0CG47 P0CG48 P11717 P13569 P15514 P16871 P20645 P21579 P22681 P25098 P25103 P30518 P30556 P32121 P35070 P35626 P41221 P42566 P49407 P51809 P52594 P53675 P53680 P61201 P62979 P62987 P63010 P63027 P98082 P98164 Q00610 Q0JRZ9 Q13098 Q13492 Q14108 Q15811 Q15836 Q15843 Q16572 Q2M2I8 Q5SW96 Q5VV43 Q6UW88 Q7L5N1 Q86SS6 Q8N9I0 Q8NBV8 Q8NC96 Q8NFH8 Q8WXE9 Q92783 Q92905 Q96B97 Q96CW1 Q96D71 Q99075 Q99627 Q99961 Q99962 Q99963 Q9BQI5 Q9BT78 Q9BT88 Q9BV40 Q9H9Q2 Q9NVZ3 Q9NY64 Q9NZM3 Q9UBC2 Q9UBW8 Q9UHD9 Q9ULV1 Q9UMX0 Q9UNS2 Q9Y6I3 Q9Y6Q2	AAK1 ABCC7 ADHR ADRB2 ADRB2R ADRBK1 ADRBK2 ADTAA ADTAB ADTB2 AF1P AGFG1 AGTR1 AGTR1A AGTR1B AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB ARB2 AREG AREGB ARH ARR1 ARR2 ARRB1 ARRB2 ARVP AT2R1 AT2R1B AVP AVPR2 B2AR BARK BARK1 BARK2 BTC CALM CBL CBL2 CD36L2 CD3D CD3G CD4 CFTR CHRM2 CIN85 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLH22 CLTA CLTB CLTC CLTCL CLTCL1 CLTCL2 CLTD CNSA1 CNSA2 CNSA3 COPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CSN1 CSN2 CSN3 CSN4 CSN5 CSN6 CSN7A CSN7B CSN8 DA41 DAB2 DERP10 DIR DIR3 DOC2 DQ1 DQ2 DTR DTS DVL2 DYT1 EGF EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EPS15R ERBB ERBB1 EREG FCHO1 FCHO2 FZD4 GLUT8 GLUTX1 GPS1 GRK2 GRK3 HBEGF HBP HEGFL HER1 HGS HIP9 HRB HRS HVIP HYPJ IGF2R IL7R ITSN ITSN1 ITSN2 JAB1 KIAA0034 KIAA0080 KIAA0109 KIAA0290 KIAA0319 KIAA0656 KIAA0899 KIAA1048 KIAA1065 KIAA1256 LDLR LDLRAP1 LIMP2 LIMPII LRP2 M6PR MPR46 MPRD MPRI N4BP4 NECAP1 NECAP2 NEDD8 NK1R PICALM PLIC1 PLIC2 POB1 RAB REPS1 REPS2 RIP RNF55 RPS27A SALF SBLF SCARB2 SDGF SGIP1 SH3D1A SH3D1B SH3D2A SH3D2B SH3D2C SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SLC18A3 SLC2A8 SNAP91 STAM STAM1 STAM2 STN1 STN2 STNB STON1 STON2 SVP65 SWAP SYB2 SYB3 SYBL1 SYT SYT1 SYT11 SYT2 SYT8 SYT9 T3D T3G TA TAC1R TACR1 TF TFRC TGFA TGN46 TGN51 TGOLN2 TOR1A TOR1B TORA TRIP15 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBQLN1 UBQLN2 V2R VACHT VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VP WNT5A	Homo sapiens (human)
Signaling by EGFR	Amphiregulin Angio-associated migratory cell protein Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 12 Disintegrin and metalloproteinase domain-containing protein 17 Epidermal growth factor receptor Epigen Leucine-rich repeats and immunoglobulin-like domains protein 1 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein FAM83A Protein FAM83B Protein FAM83D Protransforming growth factor alpha	O14672 O14944 O43184 P00533 P01133 P01135 P15514 P35070 P78536 Q13685 Q5T0W9 Q6UW88 Q86UY5 Q96JA1 Q99075 Q9H4H8	AAMP ADAM10 ADAM12 ADAM17 AREG AREGB BTC C20orf129 C6orf143 CSVP DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG FAM83A FAM83B FAM83D HBEGF HEGFL HER1 KUZ LIG1 LRIG1 MADM MLTN SDGF TACE TGFA TSGP	Homo sapiens (human)
NOD1/2 Signaling Pathway	Angio-associated migratory cell protein Baculoviral IAP repeat-containing protein 2 Baculoviral IAP repeat-containing protein 3 Caspase recruitment domain-containing protein 9 Caspase-1 Caspase-2 Caspase-4 Caspase-8 Caspase-9 Dual specificity mitogen-activated protein kinase kinase 6 E3 ubiquitin-protein ligase Itchy homolog Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 12 Mitogen-activated protein kinase 13 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Nucleoprotein Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 Receptor-interacting serine/threonine-protein kinase 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Tumor necrosis factor alpha-induced protein 3 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin-conjugating enzyme E2 N Ubiquitin-conjugating enzyme E2 variant 1	O14920 O15111 O15264 O43187 O43318 O43353 P0DTC9 P21580 P29466 P42575 P49662 P51617 P52564 P53778 P55211 P61088 Q13404 Q13489 Q13490 Q13685 Q14790 Q15750 Q15759 Q16539 Q8N5C8 Q96J02 Q9H257 Q9HC29 Q9NQC7 Q9NYJ8 Q9Y239 Q9Y4K3 Q9Y6K9	AAMP API1 API2 BIRC2 BIRC3 BLU CARD15 CARD4 CARD9 CARDIAK CASP1 CASP2 CASP4 CASP8 CASP9 CHUK CROC1 CSBP CSBP1 CSBP2 CSPB1 CYLD CYLD1 ERK6 FIP3 ICH1 ICH2 IKBKB IKBKG IKKA IKKB IL1BC IL1BCE IRAK IRAK1 IRAK2 ITCH KIAA0733 KIAA0849 MAP2K6 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 MAPK11 MAPK12 MAPK13 MAPK14 MCH5 MCH6 MEK6 MIHB MIHC MKK6 MXI2 N NEDD2 NEMO NOD1 NOD2 OTUD7C PRKM11 PRKM13 PRKMK6 RICK RIP2 RIPK2 RNF48 RNF49 RNF85 SAPK2 SAPK2A SAPK2B SAPK3 SAPK4 SKK3 TAB1 TAB2 TAB3 TAK1 TCF16 TNFAIP3 TRAF6 UBE2N UBE2V UBE2V1 UEV1	Homo sapiens (human)
Thromboxane signalling through TP receptor	Angio-associated migratory cell protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-13 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Thromboxane A2 receptor	O14610 O14775 O60262 O95837 P16520 P21731 P29992 P30679 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q13685 Q14344 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	AAMP GA11 GAQ GNA11 GNA13 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 TBXA2R	Homo sapiens (human)
Signaling by VEGF	Angio-associated migratory cell protein Vascular endothelial growth factor A, long form	P15692 Q13685	AAMP VEGF VEGFA	Homo sapiens (human)
Dissolution of Fibrin Clot	Alpha-2-antiplasmin Annexin A2 Glia-derived nexin Histidine-rich glycoprotein Plasminogen activator inhibitor 1 Plasminogen activator inhibitor 2 Plasminogen Protein S100-A10 Serpin B6 Serpin B8 Tissue-type plasminogen activator Urokinase plasminogen activator surface receptor Urokinase-type plasminogen activator	P00747 P00749 P00750 P04196 P05120 P05121 P07093 P07355 P08697 P35237 P50452 P60903 Q03405	AAP ANX2 ANX2L4 ANX2LG ANXA2 CAL1H CAL1L CLP11 HRG LPC2D MO3 PAI1 PAI2 PI6 PI7 PI8 PLANH1 PLANH2 PLAT PLAU PLAUR PLG PLI PN1 PTI S100A10 SERPINB2 SERPINB6 SERPINB8 SERPINE1 SERPINE2 SERPINF2 UPAR	Homo sapiens (human)
Cytosolic tRNA aminoacylation	Alanine--tRNA ligase, cytoplasmic Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Asparagine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Bifunctional glutamate/proline--tRNA ligase Cysteine--tRNA ligase, cytoplasmic Eukaryotic translation elongation factor 1 epsilon-1 Glutamine--tRNA ligase Glycine--tRNA ligase Histidine--tRNA ligase, cytoplasmic Inorganic pyrophosphatase Isoleucine--tRNA ligase, cytoplasmic Leucine--tRNA ligase, cytoplasmic Lysine--tRNA ligase Methionine--tRNA ligase, cytoplasmic Phenylalanine--tRNA ligase alpha subunit Phenylalanine--tRNA ligase beta subunit Serine--tRNA ligase, cytoplasmic Threonine--tRNA ligase 1, cytoplasmic Tryptophan--tRNA ligase, cytoplasmic Tyrosine--tRNA ligase, cytoplasmic Valine--tRNA ligase	O43324 O43776 P07814 P12081 P14868 P23381 P26639 P26640 P41250 P41252 P47897 P49588 P49589 P49591 P54136 P54577 P56192 Q12904 Q13155 Q15046 Q15181 Q9NSD9 Q9P2J5 Q9Y285	AARS AARS1 AIMP1 AIMP2 AIMP3 CARS CARS1 DARS DARS1 EEF1E1 EMAP2 EPRS EPRS1 FARS FARSA FARSB FARSL FARSLA FARSLB FRSB G7A GARS GARS1 GLNS HARS HARS1 HRS IARS IARS1 IFI53 IOPPP JTV1 KARS KARS1 KIAA0070 KIAA1352 LARS LARS1 MARS MARS1 NARS NARS1 NRS P18 PARS PP PPA1 QARS QARS1 QPRS RARS RARS1 SARS SARS1 SCYE1 SERS TARS TARS1 VARS VARS1 VARS2 WARS WARS1 WRS YARS YARS1	Homo sapiens (human)
Mitochondrial tRNA aminoacylation	Alanine--tRNA ligase, mitochondrial Asparaginyl-tRNA synthetase Aspartate--tRNA ligase, mitochondrial Glutamine--tRNA ligase Glycine--tRNA ligase Histidine--tRNA ligase, mitochondrial Inorganic pyrophosphatase 2, mitochondrial Isoleucine--tRNA ligase, mitochondrial Leucine--tRNA ligase, mitochondrial Lysine--tRNA ligase Methionine--tRNA ligase, mitochondrial Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial Phenylalanine--tRNA ligase, mitochondrial Probable arginine--tRNA ligase, mitochondrial Probable cysteine--tRNA ligase, mitochondrial Probable proline--tRNA ligase, mitochondrial Serine--tRNA ligase, mitochondrial Threonine--tRNA ligase, mitochondrial Tryptophan--tRNA ligase, mitochondrial Tyrosine--tRNA ligase, mitochondrial Valine--tRNA ligase, mitochondrial	O95363 P41250 P47897 P49590 Q15031 Q15046 Q5JPH6 Q5JTZ9 Q5ST30 Q5T160 Q6PI48 Q7L3T8 Q96GW9 Q96I59 Q9BW92 Q9H2U2 Q9HA77 Q9NP81 Q9NSE4 Q9UGM6 Q9Y2Z4	AARS2 AARSL CARS2 DARS2 EARS2 FARS1 FARS2 GARS GARS1 HARS2 HARSL HARSR HO3 IARS2 KARS KARS1 KIAA0028 KIAA0070 KIAA1270 KIAA1885 KIAA1970 LARS2 MARS2 NARS2 PARS2 PPA2 QARS QARS1 RARS2 RARSL SARS2 SARSM TARS2 TARSL1 VARS2 VARS2L VARSL WARS2 YARS2	Homo sapiens (human)
Vitamin B5 (pantothenate) metabolism	4'-phosphopantetheine phosphatase Autotaxin Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 Fatty acid synthase L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mitochondrial coenzyme A diphosphatase NUDT8 Mitochondrial coenzyme A transporter SLC25A42 PDZ domain-containing protein 11 Pantetheinase Pantetheine hydrolase VNN2 Sodium-dependent multivitamin transporter Solute carrier family 25 member 16	O14638 O95497 O95498 P16260 P22413 P49327 Q13822 Q5EBL8 Q86VD7 Q8WV74 Q9NRN7 Q9NVE7 Q9Y289	AASDHPPT AIPP1 ATX ENPP1 ENPP2 ENPP3 FAS FASN GDA M6S1 NPPS NUDT8 PANK4 PC1 PDNP1 PDNP2 PDNP3 PDZD11 PDZK11 PISP SLC25A16 SLC25A42 SLC5A6 SMVT VNN1 VNN2	Homo sapiens (human)
COPII-mediated vesicle transport	Alpha-1-antitrypsin Alpha-soluble NSF attachment protein Amphiregulin BET1 homolog Beta-soluble NSF attachment protein CD59 glycoprotein Casein kinase I isoform delta Cathepsin Z Coagulation factor V Coagulation factor VIII Collagen alpha-1(VII) chain Dipeptidyl peptidase 1 Folate receptor alpha Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor 1 Golgi SNAP receptor complex member 2 Golgi reassembly-stacking protein 1 Golgin subfamily A member 2 Guanine nucleotide-exchange factor SEC12 Multiple coagulation factor deficiency protein 2 Protein ERGIC-53-like Protein ERGIC-53 Protein SEC13 homolog Protein TFG Protein cornichon homolog 1 Protein cornichon homolog 2 Protein cornichon homolog 3 Protein transport protein Sec16A Protein transport protein Sec16B Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Protein transport protein Sec31A Protein transport protein Sec31B Protransforming growth factor alpha Ras-related protein Rab-1A Ras-related protein Rab-1B SEC23-interacting protein Sec1 family domain-containing protein 1 Serine/threonine-protein phosphatase 6 catalytic subunit Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A Serine/threonine-protein phosphatase 6 regulatory subunit 1 Serine/threonine-protein phosphatase 6 regulatory subunit 3 Small COPII coat GTPase SAR1B Synaptobrevin homolog YKT6 Syntaxin-17 Syntaxin-5 TBC1 domain family member 20 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 1 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 3 Trafficking protein particle complex subunit 4 Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 VIP36-like protein Vesicle-fusing ATPase Vesicle-trafficking protein SEC22a Vesicle-trafficking protein SEC22b Vesicle-trafficking protein SEC22c Vesicular integral-membrane protein VIP36	O00743 O14653 O15027 O15084 O15155 O15498 O43617 O60763 O75396 O75865 O94855 O94979 O95406 O95486 O95487 P00451 P01009 P01135 P0DI81 P12259 P13987 P15328 P15514 P42261 P46459 P48553 P48730 P49257 P49755 P53634 P53992 P54920 P55735 P56962 P62820 Q02388 Q08379 Q12907 Q13190 Q15363 Q15436 Q5H9R7 Q6PI25 Q86SZ2 Q8IUR0 Q8NI22 Q8TBE1 Q8WVM8 Q92734 Q96BZ9 Q96IW7 Q96JE7 Q96Q05 Q99747 Q9BQQ3 Q9BRL7 Q9H0U4 Q9H0V9 Q9H115 Q9HAT1 Q9HCU5 Q9NQW1 Q9UBR2 Q9UL33 Q9UPN7 Q9Y296 Q9Y5R8 Q9Y6B6 Q9Y6Y8	AAT ANKRD28 AREG AREGB BET1 BET3 BET5 C11orf23 C14orf163 C20orf140 C5orf8 CD59 CNIH CNIH1 CNIH2 CNIH3 CNIL COL7A1 CPPI CSNK1D CTSC CTSZ D3S1231E EHOC1 ERGIC53 ERGL F5 F5F8D F8 F8C FOLR FOLR1 GLUA1 GLUH1 GLUR1 GOLGA2 GOLPH5 GORASP1 GOSR2 GRASP65 GRIA1 GS27 HCKID KIAA0079 KIAA0310 KIAA0379 KIAA0755 KIAA0905 KIAA0917 KIAA1115 KIAA1558 KIAA1882 KIAA1928 LMAN1 LMAN1L LMAN2 LMAN2L LZTR2 MCFD2 MIC11 MIN1 MIN2 MIN3 MSK21 MUM2 NAPA NAPB NAPG NIBP NSF PI PP6R1 PP6R3 PPP6 PPP6C PPP6R1 PPP6R3 PREB RAB1 RAB1A RAB1B RGPR RNP24 SAPL SAPS1 SAPS3 SAR1B SARA2 SARB SBDN SCFD1 SDGF SDNSF SEC12 SEC13 SEC13A SEC13L1 SEC13R SEC16 SEC16A SEC16B SEC16L SEC16S SEC22A SEC22B SEC22C SEC22L1 SEC22L2 SEC22L3 SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SEC31B SEC31L1 SEC31L2 SEDL SERPINA1 SNAPA SNAPB SNAPG STX17 STX5 STX5A STXBP1L2 TBC1D20 TFG TGFA TMED10 TMED2 TMEM1 TMP21 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 USO1 VDP VIPL YKT6	Homo sapiens (human)
Cargo concentration in the ER	Alpha-1-antitrypsin Amphiregulin CD59 glycoprotein Cathepsin Z Coagulation factor V Coagulation factor VIII Collagen alpha-1(VII) chain Dipeptidyl peptidase 1 Folate receptor alpha Glutamate receptor 1 Golgi SNAP receptor complex member 2 Guanine nucleotide-exchange factor SEC12 Melanoma inhibitory activity protein 2 Multiple coagulation factor deficiency protein 2 Protein ERGIC-53-like Protein ERGIC-53 Protein cornichon homolog 1 Protein cornichon homolog 2 Protein cornichon homolog 3 Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Protransforming growth factor alpha Small COPII coat GTPase SAR1B Syntaxin-5 Transmembrane emp24 domain-containing protein 10 Transmembrane emp24 domain-containing protein 2 Transport and Golgi organization protein 1 homolog VIP36-like protein Vesicle-trafficking protein SEC22b Vesicular integral-membrane protein VIP36	O14653 O75396 O94855 O95406 O95486 O95487 P00451 P01009 P01135 P12259 P13987 P15328 P15514 P42261 P49257 P49755 P53634 P53992 Q02388 Q12907 Q13190 Q15363 Q15436 Q5JRA6 Q6PI25 Q8NI22 Q8TBE1 Q96PC5 Q9H0V9 Q9HAT1 Q9HCU5 Q9UBR2 Q9Y6B6	AAT AREG AREGB C5orf8 CD59 CNIH CNIH1 CNIH2 CNIH3 CNIL COL7A1 CPPI CTAGE5 CTSC CTSZ ERGIC53 ERGL F5 F5F8D F8 F8C FOLR FOLR1 GLUA1 GLUH1 GLUR1 GOSR2 GRIA1 GS27 KIAA0079 KIAA0268 KIAA0755 LMAN1 LMAN1L LMAN2 LMAN2L MCFD2 MEA11 MEA6 MGEA11 MGEA6 MIA2 MIA3 MIC11 MIN1 MIN2 MIN3 MSK21 PI PREB RNP24 SAR1B SARA2 SARB SDGF SDNSF SEC12 SEC22B SEC22L1 SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 STX5 STX5A TANGO TGFA TMED10 TMED2 TMP21 VIPL	Homo sapiens (human)
Pyruvate metabolism	Alanine aminotransferase 1 L-lactate dehydrogenase A chain L-lactate dehydrogenase A-like 6A L-lactate dehydrogenase A-like 6B L-lactate dehydrogenase B chain L-lactate dehydrogenase C chain Lactoylglutathione lyase Mitochondrial pyruvate carrier 1-like protein Mitochondrial pyruvate carrier 1 Mitochondrial pyruvate carrier 2 NAD-dependent malic enzyme, mitochondrial NADP-dependent malic enzyme, mitochondrial NADP-dependent malic enzyme Non-selective voltage-gated ion channel VDAC1 Oxaloacetate tautomerase FAHD1, mitochondrial Pyruvate carboxylase, mitochondrial	O95563 P00338 P07195 P07864 P0DKB6 P11498 P21796 P23368 P24298 P48163 Q04760 Q16798 Q6P587 Q6ZMR3 Q9BYZ2 Q9Y5U8	AAT1 BRP44 BRP44L C16orf36 FAHD1 GLO1 GPT GPT1 LDH3 LDHA LDHAL6 LDHAL6A LDHAL6B LDHB LDHC LDHL LDHL2 LDHX ME1 ME2 ME3 MPC1 MPC1L MPC2 PC VDAC VDAC1 YISKL	Homo sapiens (human)
NRAGE signals death through JNK	A-kinase anchor protein 13 Active breakpoint cluster region-related protein Bcl-2-like protein 11 Bcl2-associated agonist of cell death Beta-nerve growth factor Ephexin-1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Intersectin-1 Kalirin Melanoma-associated antigen D1 Mitogen-activated protein kinase 8 Neuroepithelial cell-transforming gene 1 protein Obscurin Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 5 Protein AATF Protein ECT2 Proto-oncogene DBL Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Ras-specific guanine nucleotide-releasing factor 2 Rho guanine nucleotide exchange factor 10-like protein Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 18 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 35 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 40 Rho guanine nucleotide exchange factor 4 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 Rho guanine nucleotide exchange factor TIAM2 Son of sevenless homolog 1 Son of sevenless homolog 2 Triple functional domain protein Tumor necrosis factor receptor superfamily member 16	A1IGU5 A5YM69 A8MVX0 O14827 O15013 O15068 O15085 O43307 O43521 O60229 O75962 O94827 O94989 P01138 P08138 P10911 P15498 P45983 P52735 P63000 P98174 Q07889 Q07890 Q12774 Q12802 Q12979 Q13009 Q14155 Q14344 Q15052 Q15811 Q5JSP0 Q5VST9 Q5VV41 Q6ZSZ5 Q7Z628 Q7Z6J4 Q8IVF5 Q8IW93 Q8N4T4 Q8N5V2 Q8TCU6 Q8TER5 Q92888 Q92934 Q92974 Q96DR7 Q96M96 Q96PE2 Q9H7P9 Q9H8V3 Q9HCE6 Q9NR80 Q9NR81 Q9NXL2 Q9NY61 Q9NZN5 Q9UKW4 Q9Y5V3	AATF ABR AKAP13 ARHDH9 ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF26 ARHGEF3 ARHGEF33 ARHGEF35 ARHGEF37 ARHGEF38 ARHGEF39 ARHGEF4 ARHGEF40 ARHGEF5 ARHGEF5L ARHGEF6 ARHGEF7 ARHGEF8 ARHGEF9 BAD BBC6 BCL2L11 BCL2L8 BIM BRX C9orf100 CHE1 COOL1 COOL2 DBL DED DUET DUO ECT2 EPHEXIN4 FGD1 FGD2 FGD3 FGD4 FGDY FRABP GNA13 GRF2 GRINCHGEF HAPIP HT31 ITSN ITSN1 JNK1 KALRN KIAA0006 KIAA0142 KIAA0294 KIAA0337 KIAA0362 KIAA0380 KIAA0382 KIAA0424 KIAA0521 KIAA0651 KIAA0720 KIAA0915 KIAA1112 KIAA1415 KIAA1556 KIAA1626 KIAA1639 KIAA2016 LARG LBC LFP40 MAGED1 MAPK8 MCF2 MCF2L NBR NET1 NGEF NGF NGFB NGFR NRAGE OBSCN OST P85SPR PAK3BP PIXA PIXB PLEKHG2 PLEKHG5 PREX1 PRKM8 RAC1 RASGRF2 SAPK1 SAPK1C SGEF SH3D1A SOLO SOS1 SOS2 STEF TC25 TEM4 TIAM1 TIAM2 TIM TNFRSF16 TRAD TRIO VAV VAV1 VAV2 VAV3 ZFYVE3 ZFYVE4 ZFYVE5 ZFYVE6	Homo sapiens (human)

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