GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1651 - 1675** of **2074** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Selenocysteine synthesis	L-seryl-tRNA(Sec) kinase Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 O-phosphoseryl-tRNA(Sec) selenium transferase Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Selenide, water dikinase 2 Selenocysteine insertion sequence-binding protein 2 Selenocysteine-specific elongation factor Serine--tRNA ligase, cytoplasmic Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	P05386 P05387 P05388 P08708 P08865 P15880 P18077 P18124 P18621 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P39019 P39023 P40429 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P49591 P50914 P57772 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q6P5R6 Q71UM5 Q8IV42 Q8TD47 Q92901 Q969Q0 Q96EH5 Q96L21 Q96T21 Q99611 Q9HD40 Q9UNX3 Q9Y3U8	BBC1 C10orf89 CCG2 D11S2243E D6S218E DXS648E EC45 EEFSEC FAU FTE1 LAMBR LAMR1 MFTL MPS1 NEDD6 PSTK QM RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SARS SARS1 SBP2 SCAR SECISBP2 SELB SEPHS2 SEPSECS SERS SPS2 SURF-3 SURF3 TRNP48 TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
Sema3A PAK dependent Axon repulsion	Cofilin-1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14786 O75051 O75914 P06241 P07332 P07900 P08238 P23528 P51805 P53667 P63000 Q13153 Q13177 Q14563 Q9HCM2 Q9UIW2	CFL CFL1 FES FPS FYN HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0463 KIAA1550 LIMK LIMK1 NOV NRP NRP1 OCT OPHN3 PAK1 PAK2 PAK3 PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B RAC1 SEMA3A SEMAD SEX TC25 VEGF165R	Homo sapiens (human)
Sema4D induced cell migration and growth-cone collapse	LIM domain kinase 1 LIM domain kinase 2 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Plexin-B1 Receptor tyrosine-protein kinase erbB-2 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Rho-related GTP-binding protein Rho6 Rho-related GTP-binding protein RhoB Rho-related GTP-binding protein RhoC Semaphorin-4D Transforming protein RhoA	O14950 O15085 O43157 O75116 P04626 P08134 P24844 P35579 P35580 P35749 P53667 P53671 P60660 P61586 P62745 Q13464 Q7Z406 Q92730 Q92854 Q9NZN5	ARH12 ARH6 ARH9 ARHA ARHB ARHC ARHGEF11 ARHGEF12 C9orf164 CD100 ERBB2 HER2 KIAA0380 KIAA0382 KIAA0407 KIAA0619 KIAA0866 KIAA2034 LARG LIMK LIMK1 LIMK2 MLC2 MLN19 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYRL2 NEU NGL PLXN5 PLXNB1 RHO12 RHO6 RHOA RHOB RHOC RND1 ROCK1 ROCK2 SEMA4D SEMAJ SEP	Homo sapiens (human)
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin-B1 Ras-related C3 botulinum toxin substrate 1 Ras-related protein R-Ras Rho GTPase-activating protein 35 Rho-related GTP-binding protein Rho6 Semaphorin-4D Transforming protein RhoA	O43157 P08581 P10301 P61586 P63000 Q92730 Q92854 Q9NRY4	ARH12 ARHA ARHGAP35 C9orf164 CD100 GRF1 GRLF1 KIAA0407 KIAA1722 MET P190A PLXN5 PLXNB1 RAC1 RHO12 RHO6 RHOA RND1 RRAS SEMA4D SEMAJ SEP TC25 p190ARHOGAP	Homo sapiens (human)
Senescence-Associated Secretory Phenotype (SASP)	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 CCAAT/enhancer-binding protein beta Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 2A Fizzy-related protein homolog Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Homeobox protein VENTX Insulin-like growth factor-binding protein 7 Interleukin-1 alpha Interleukin-6 Interleukin-8 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Protein c-Fos Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Signal transducer and activator of transcription 3 Transcription factor Jun Transcription factor p65 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 O60814 O95231 P01100 P01583 P04908 P05231 P05412 P06899 P0C5Y9 P0CG47 P0CG48 P10145 P11802 P16104 P17676 P19838 P20248 P20671 P23527 P24941 P27361 P28482 P30260 P33778 P38936 P40763 P42771 P42772 P42773 P46527 P51668 P51812 P51965 P55273 P57053 P58876 P60006 P62805 P62807 P62979 P62987 P68431 P78396 P84243 Q00534 Q04206 Q13042 Q13164 Q15349 Q15418 Q16270 Q16763 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q8NHZ8 Q93077 Q93079 Q96A08 Q96DE5 Q96KQ7 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H1A4 Q9H9B1 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 APRF BAT8 BMK1 C10orf104 C11orf51 C6orf30 C9orf17 CAP20 CCN1 CCNA CCNA1 CCNA2 CDC16 CDC23 CDC26 CDC27 CDH1 CDK2 CDK4 CDK6 CDKN1 CDKN1A CDKN1B CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 CEBPB CENP-27 CIP1 CXCL8 D0S1430E D17S978E E2EPF EHMT1 EHMT2 ERK1 ERK2 ERK5 EUHMTASE1 FOS FYR FZR FZR1 G0S7 G9A GLP H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HPX42B IFNB2 IGFBP7 IL1A IL1F1 IL6 IL8 ISPK1 JUN KIAA1242 KIAA1406 KIAA1876 KIP1 KMT1C KMT1D MAC25 MAPK1 MAPK3 MAPK7 MAPKAPK1A MAPKAPK1B MAPKAPK1C MDA6 MTS1 MTS2 NFKB1 NFKB3 NG36 PIC1 PRKM1 PRKM2 PRKM3 PRKM7 PSF RELA RPS27A RPS6KA1 RPS6KA2 RPS6KA3 RSK1 RSK2 RSK3 SDI1 SFT STAT3 TCF5 TSG24 TSH2B UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S VENTX VENTX2 WAF1 p27	Homo sapiens (human)
Sensing of DNA Double Strand Breaks	DNA repair protein RAD50 Double-strand break repair protein MRE11 Histone acetyltransferase KAT5 Importin subunit alpha-1 Nibrin Serine-protein kinase ATM	O60934 P49959 P52292 Q13315 Q92878 Q92993	ATM HNGS1 HTATIP KAT5 KPNA2 MRE11 MRE11A NBN NBS NBS1 P95 RAD50 RCH1 SRP1 TIP60	Homo sapiens (human)
Sensory perception of salty taste	Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit delta Amiloride-sensitive sodium channel subunit gamma Calcium homeostasis modulator protein 1 Calcium homeostasis modulator protein 3	P37088 P51168 P51170 P51172 Q86XJ0 Q8IU99	CALHM1 CALHM3 DNACH FAM26A FAM26C SCNN1 SCNN1A SCNN1B SCNN1D SCNN1G	Homo sapiens (human)
Sensory perception of sweet, bitter, and umami (glutamate) taste	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 Calcium homeostasis modulator protein 1 Calcium homeostasis modulator protein 3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 4 Sodium channel protein type 2 subunit alpha Sodium channel protein type 3 subunit alpha Sodium channel protein type 9 subunit alpha Sodium channel regulatory subunit beta-1 Sodium channel regulatory subunit beta-2 Sodium channel subunit beta-4 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 43 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Transient receptor potential cation channel subfamily M member 4 Transient receptor potential cation channel subfamily M member 5	A8MTJ3 O60939 P16520 P59533 P59534 P59535 P59536 P59537 P59538 P59540 P59541 P59543 P59544 P62873 Q00722 Q07699 Q13255 Q14573 Q14833 Q15858 Q7RTX0 Q7RTX1 Q86XJ0 Q8IU99 Q8IWT1 Q8TD43 Q8TE23 Q99250 Q9NY46 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9NZQ8 Q9P2W3	CALHM1 CALHM3 FAM26A FAM26C GNAT3 GNB1 GNB3 GNG13 GPR60 GPR70 GPR71 GPRC1A GPRC1D GRM1 GRM4 HBA ITPR3 KIAA1356 LTRPC4 LTRPC5 MGLUR1 MGLUR4 MTR1 NAC2 NAC3 NENA PLCB2 PTC SCN1B SCN2A SCN2A1 SCN2A2 SCN2B SCN3A SCN4B SCN9A T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R20 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R43 TAS2R44 TAS2R46 TAS2R47 TAS2R49 TAS2R5 TAS2R50 TAS2R7 TAS2R8 TR1 TR2 TR3 TRPM4 TRPM5	Homo sapiens (human)	G58161NS
Sensory processing of sound by inner hair cells of the cochlea	Band 4.1-like protein 1 Band 4.1-like protein 3 Cadherin-23 Calcium and integrin-binding family member 2 Calcium-activated potassium channel subunit alpha-1 Calcium-activated potassium channel subunit beta-1 Calcium-binding protein 1 Calcium-binding protein 2 Chloride intracellular channel protein 5 DnaJ homolog subfamily C member 5 Epidermal growth factor receptor kinase substrate 8-like protein 2 Epidermal growth factor receptor kinase substrate 8 Espin-like protein Espin Ezrin F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit beta Fascin-2 Glutaredoxin domain-containing cysteine-rich protein 1 Glutaredoxin domain-containing cysteine-rich protein 2 Harmonin LHFPL tetraspan subfamily member 5 protein Leucine-rich repeat-containing protein 52 Moesin Myosin-9 Myosin-IIIa Myosin-IIIb Otoferlin Pejvakin Peripheral plasma membrane protein CASK Plasma membrane calcium-transporting ATPase 1 Plastin-1 Potassium voltage-gated channel subfamily KQT member 4 Protein bassoon Protein piccolo Protocadherin-15 Radixin Ras-related protein Rab-3A Rho family-interacting cell polarization regulator 2 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Stereocilin Synapsin-1 Synaptophysin Synaptosomal-associated protein 25 Syntaxin-1A Taperin Transmembrane channel-like protein 1 Transmembrane channel-like protein 2 Transmembrane inner ear expressed protein Twinfilin-1 Twinfilin-2 Unconventional myosin-Ic Unconventional myosin-VIIa Unconventional myosin-XV Vesicle-associated membrane protein 2 Vesicular glutamate transporter 3 Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel subunit alpha-2/delta-2 Whirlin Xin actin-binding repeat-containing protein 2 pre-mRNA splicing regulator USH1G	A4UGR9 A6NFK2 A8MXD5 B1AK53 O00159 O14926 O14936 O75838 P08247 P15311 P17600 P20020 P20336 P26038 P35241 P35579 P47755 P47756 P52907 P56696 P60880 P63027 Q01082 Q01668 Q08289 Q0ZLH3 Q12791 Q12792 Q12929 Q13402 Q13813 Q14651 Q16558 Q16623 Q495M9 Q4KMQ1 Q6IBS0 Q6ZVH7 Q7RTU9 Q8N7C0 Q8NDX2 Q8NEV4 Q8NEW7 Q8TAF8 Q8TDI7 Q8TDI8 Q8WXR4 Q96QU1 Q9H251 Q9H3Z4 Q9H4G0 Q9H6S3 Q9HC10 Q9NPB3 Q9NY47 Q9NZA1 Q9NZU7 Q9P202 Q9UKN7 Q9UPA5 Q9Y2J2 Q9Y4F9 Q9Y6N9 Q9Y6V0	ACZ AIE75 ATP2B1 BSN C20orf145 C6orf32 C9orf75 CABP1 CABP2 CACH3 CACN4 CACNA1D CACNA2D2 CACNB2 CACNL1A2 CACNLB2 CAPZA1 CAPZA2 CAPZB CASK CCHL1A2 CDH23 CIB2 CLIC5 CLN4 CMYA3 DAL1 DFNB25 DFNB31 DFNB36 DFNB59 DIFF48 DNAJC5 EPB41L1 EPB41L3 EPS8 EPS8L2 EPS8R2 ESPN ESPNL EZR FAM65B FER1L2 FSCN2 GRXCR1 GRXCR2 KCNMA KCNMA1 KCNMB1 KCNQ4 KIAA0338 KIAA0386 KIAA0434 KIAA0558 KIAA0559 KIAA0987 KIAA1526 KIAA1774 KIAA1812 KIP2 LHFPL5 LIN2 LRRC52 MSN MYH9 MYO15 MYO15A MYO1C MYO3A MYO3B MYO7A MYSB NEAS OTOF PCDH15 PCLO PJVK PL48 PLS1 PMCA1 PTK9 PTK9L RAB3A RDX RIPOR2 SANS SLC17A8 SLO SNAP SNAP25 SPTA2 SPTAN1 SPTB2 SPTBN1 STRC STX1 STX1A SYB2 SYN1 SYP TMC1 TMC2 TMHS TMIE TPRN TWF1 TWF2 USH1B USH1C USH1F USH1G VAMP2 VGLUT3 VIL2 WHRN XIRP2 ZNF231	Homo sapiens (human)
Sensory processing of sound by outer hair cells of the cochlea	55 kDa erythrocyte membrane protein Band 4.1-like protein 1 Band 4.1-like protein 3 Cadherin-23 Calcium and integrin-binding family member 2 Chloride intracellular channel protein 5 Epidermal growth factor receptor kinase substrate 8-like protein 2 Epidermal growth factor receptor kinase substrate 8 Espin-like protein Espin Ezrin Fascin-2 Gelsolin Glutaredoxin domain-containing cysteine-rich protein 1 Glutaredoxin domain-containing cysteine-rich protein 2 Harmonin LHFPL tetraspan subfamily member 5 protein Moesin Myosin-9 Myosin-IIIa Myosin-IIIb Otogelin-like protein Otogelin Pejvakin Peripheral plasma membrane protein CASK Plastin-1 Potassium voltage-gated channel subfamily KQT member 4 Prestin Protocadherin-15 Radixin Rho family-interacting cell polarization regulator 2 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Stereocilin Taperin Transmembrane channel-like protein 1 Transmembrane channel-like protein 2 Transmembrane inner ear expressed protein Twinfilin-1 Twinfilin-2 Unconventional myosin-Ic Unconventional myosin-VIIa Unconventional myosin-XV Whirlin Xin actin-binding repeat-containing protein 2 pre-mRNA splicing regulator USH1G	A4UGR9 A6NFK2 A8MXD5 B1AK53 O00159 O14926 O14936 O75838 P06396 P15311 P26038 P35241 P35579 P56696 P58743 Q00013 Q01082 Q0ZLH3 Q12792 Q12929 Q13402 Q13813 Q14651 Q3ZCN5 Q495M9 Q4KMQ1 Q6IBS0 Q6ZRI0 Q6ZVH7 Q7RTU9 Q8NEV4 Q8NEW7 Q8TAF8 Q8TDI7 Q8TDI8 Q8WXR4 Q96QU1 Q9H251 Q9H4G0 Q9H6S3 Q9NZA1 Q9P202 Q9UKN7 Q9Y2J2 Q9Y4F9 Q9Y6N9	AIE75 C12orf64 C20orf145 C6orf32 C9orf75 CASK CDH23 CIB2 CLIC5 CMYA3 DAL1 DFNB25 DFNB31 DFNB36 DFNB59 DIFF48 DXS552E EMP55 EPB41L1 EPB41L3 EPS8 EPS8L2 EPS8R2 ESPN ESPNL EZR FAM65B FSCN2 GRXCR1 GRXCR2 GSN KCNQ4 KIAA0338 KIAA0386 KIAA0987 KIAA1526 KIAA1774 KIAA1812 KIP2 LHFPL5 LIN2 MPP1 MSN MYH9 MYO15 MYO15A MYO1C MYO3A MYO3B MYO7A NEAS OTGN OTOG OTOGL PCDH15 PJVK PL48 PLS1 PRES PTK9 PTK9L RDX RIPOR2 SANS SLC26A5 SPTA2 SPTAN1 SPTB2 SPTBN1 STRC TMC1 TMC2 TMHS TMIE TPRN TWF1 TWF2 USH1B USH1C USH1F USH1G VIL2 WHRN XIRP2	Homo sapiens (human)
Separation of Sister Chromatids	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cohesin subunit SA-1 Cohesin subunit SA-2 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Double-strand-break repair protein rad21 homolog Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 SKA complex subunit 1 Securin Separin Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Small ribosomal subunit protein eS27 Sororin Spindle and kinetochore-associated protein 2 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Wings apart-like protein homolog ZW10 interactor	O00139 O00231 O00232 O00487 O00762 O14576 O14777 O14818 O14980 O15392 O43237 O43242 O43264 O43683 O43684 O60216 O60566 O75122 O95229 O95997 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30153 P30154 P30260 P30622 P35998 P36873 P42677 P43034 P43686 P46060 P48556 P49450 P49454 P49720 P49721 P49792 P50748 P51665 P51668 P51965 P53350 P55735 P57740 P60006 P60896 P60900 P62191 P62195 P62333 P62714 P62979 P62987 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13042 Q13200 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14674 Q14683 Q14738 Q15008 Q15172 Q15173 Q15691 Q16186 Q16537 Q16763 Q29RF7 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q7Z5K2 Q8N0S6 Q8N2Z9 Q8N3U4 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NHZ8 Q8NI77 Q8WUM0 Q8WVK7 Q8WVM7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96DE5 Q96EA4 Q96FF9 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99436 Q99460 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H1A4 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NTI5 Q9NXR1 Q9NYG5 Q9P258 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13 Q9UNM6 Q9UQE7 Q9Y266 Q9Y6D9 Q9Y6G9	ADRM1 AHCTF1 AIK2 AIM1 AIRK2 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 API4 APITD1 APRIN ARK2 AS3 AURKB B9D2 BAM BIRC5 BMH BUB1 BUB1B BUB1L BUB3 BUBR1 C10orf104 C11orf51 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 C7orf76 C9orf17 CASC5 CCDC99 CDC16 CDC20 CDC23 CDC26 CDC27 CDCA1 CDCA5 CDCA8 CENP-27 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CSPG6 CYLN1 D0S1430E D17S978E D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DSS1 DXS423E DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 E2EPF EAP1 ELYS EOPA ERCC6L ESP1 ESPL1 FAAP16 FAM33A FOE FSHPRH1 GP110 HC2 HC3 HC8 HC9 HDLC1 HEC HEC1 HR21 HSPC IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0078 KIAA0097 KIAA0107 KIAA0165 KIAA0166 KIAA0178 KIAA0197 KIAA0261 KIAA0325 KIAA0622 KIAA0627 KIAA0648 KIAA0979 KIAA1361 KIAA1406 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LMPX LMPY LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MB1 MCM21R MDCR MDS MHF1 MIP224 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MOV34L MPS1 MSS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NU NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 NXP1 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PDS5 PDS5A PDS5B PESCRG3 PFAAP4 PICH PLK PLK1 PMF1 POH1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTTG PTTG1 RAD21 RANBP2 RANGAP1 RCC2 ROD RPS27 RPS27A RSN SA1 SA2 SB1.8 SCC1 SCC3 SD SEC13 SEC13A SEC13L1 SEC13R SEM1 SFT SGO1 SGO2 SGOL1 SGOL2 SHFDG1 SHFM1 SKA1 SKA2 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STAG1 STAG2 STK1 STK12 STK5 SUG1 SUG2 TAOK1 TBP1 TBP7 TD60 TMBS62 TRAP2 TSG24 TUTR1 TXBP181 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S WAPAL WAPL X XPO1 Y Z ZW10 ZWILCH ZWINT	Homo sapiens (human)
Serine biosynthesis	D-3-phosphoglycerate dehydrogenase Phosphoserine aminotransferase Phosphoserine phosphatase Serine incorporator 1 Serine incorporator 2 Serine incorporator 3 Serine incorporator 4 Serine incorporator 5 Serine racemase	A6NH21 O43175 P78330 Q13530 Q86VE9 Q96SA4 Q9GZT4 Q9NRX5 Q9Y617	C5orf12 DIFF33 KIAA1253 PGDH3 PHGDH PSA PSAT1 PSPH SERINC1 SERINC2 SERINC3 SERINC4 SERINC5 SRR TDE1 TDE1L TDE2 TDE2L	Homo sapiens (human)
Serotonin Neurotransmitter Release Cycle	Complexin-1 Liprin-alpha-1 Liprin-alpha-2 Liprin-alpha-3 Liprin-alpha-4 Peripheral-type benzodiazepine receptor-associated protein 1 Protein unc-13 homolog B Ras-related protein Rab-3A Regulating synaptic membrane exocytosis protein 1 Synapsin-1 Synapsin-2 Synapsin-3 Synaptic vesicular amine transporter Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Vesicle-associated membrane protein 2	O14795 O14810 O14994 O75145 O75334 O75335 O95153 P17600 P20336 P21579 P60880 P63027 Q05940 Q13136 Q16623 Q86UR5 Q92777	BZRAP1 CPLX1 KIAA0340 KIAA0612 KIAA0654 KIAA0897 LIP1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RAB3IP2 RBP1 RIM1 RIMBP1 RIMS1 SLC18A2 SNAP SNAP25 STX1 STX1A SVMT SVP65 SYB2 SYN1 SYN2 SYN3 SYT SYT1 TSPOAP1 UNC13 UNC13B VAMP2 VMAT2	Homo sapiens (human)
Serotonin and melatonin biosynthesis	Acetylserotonin O-methyltransferase Aromatic-L-amino-acid decarboxylase Serotonin N-acetyltransferase Tryptophan 5-hydroxylase 1 Tryptophan 5-hydroxylase 2	P17752 P20711 P46597 Q16613 Q8IWU9	AADC AANAT ASMT DDC NTPH SNAT TPH TPH1 TPH2 TPRH TRPH	Homo sapiens (human)
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7	P08908 P28221 P28222 P28223 P28335 P28566 P30939 P34969 P41595 P47898 P50406 Q13639	ADRB2RL1 ADRBRL1 HTR1A HTR1B HTR1C HTR1D HTR1DA HTR1DB HTR1E HTR1EL HTR1F HTR2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 HTRL	Homo sapiens (human)
Sialic acid metabolism	Alpha-2,8-sialyltransferase 8B Alpha-2,8-sialyltransferase 8E Alpha-2,8-sialyltransferase 8F Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 1 Beta-galactoside alpha-2,6-sialyltransferase 2 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase CMP-sialic acid transporter Lactosylceramide alpha-2,3-sialyltransferase Lysosomal protective protein N-acetylneuraminate lyase N-acylneuraminate cytidylyltransferase N-acylneuraminate-9-phosphatase Sialic acid synthase Sialidase-1 Sialidase-2 Sialidase-3 Sialidase-4 Sialin Type 2 lactosamine alpha-2,3-sialyltransferase	O15466 O43173 P10619 P15907 P16278 P61647 P78382 Q11201 Q11203 Q11206 Q16842 Q8NDV1 Q8NFW8 Q8TBE9 Q8WWR8 Q92185 Q92186 Q92187 Q969X2 Q96JF0 Q99519 Q9BVH7 Q9BXD5 Q9H4F1 Q9NR45 Q9NRA2 Q9NSC7 Q9UJ37 Q9UNP4 Q9UQ49 Q9Y223 Q9Y274 Q9Y3R4	C1orf13 C20orf147 CGS23 CMAS CTSA ELNR1 GLB1 GLCNE GNE HDHD4 IBM2 KIAA1877 NANH NANP NANS NANTA3 NEU1 NEU2 NEU3 NEU4 NPL PPGB PST PST1 SAS SIAT1 SIAT10 SIAT2 SIAT3C SIAT4 SIAT4A SIAT4B SIAT4C SIAT6 SIAT7A SIAT7B SIAT7C SIAT7D SIAT7E SIAT7F SIAT8 SIAT8A SIAT8B SIAT8C SIAT8D SIAT8E SIAT8F SIAT9 SIATL1 SLC17A5 SLC35A1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL1 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 ST8SIA6 STHM STX STZ	Homo sapiens (human)
Signal attenuation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 Son of sevenless homolog 1	P01308 P06213 P27361 P28482 P29353 P35568 Q07889 Q13322 Q9Y4H2	ERK1 ERK2 GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 SHC SHC1 SHCA SOS1	Homo sapiens (human)
Signal regulatory protein family interactions	FYN-binding protein 1 Focal adhesion kinase 1 Leukocyte surface antigen CD47 Protein-tyrosine kinase 2-beta Signal-regulatory protein beta-1 Signal-regulatory protein gamma Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 6 Tyrosine-protein phosphatase non-receptor type substrate 1	O00241 O15117 O43914 O75563 P29350 P78324 Q05397 Q06124 Q08722 Q14289 Q9P1W8	BIT CD47 DAP12 FAK FAK1 FAK2 FYB FYB1 HCP KARAP MER6 MFR MYD1 PRAP PTK2 PTK2B PTP1C PTP2C PTPN11 PTPN6 PTPNS1 PYK2 RA70 RAFTK SAPS SCAP2 SHPS1 SHPTP2 SIRP SIRPA SIRPB1 SIRPB2 SIRPG SKAP2 SKAP55R SLAP130 TYROBP	Homo sapiens (human)
Signal transduction by L1	Casein kinase II subunit alpha' Casein kinase II subunit alpha Casein kinase II subunit beta Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epidermal growth factor receptor Guanine nucleotide exchange factor VAV2 Integrin alpha-5 Integrin alpha-9 Integrin alpha-IIb Integrin alpha-V Integrin beta-1 Integrin beta-3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Neural cell adhesion molecule L1 Neuropilin-1 Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1	O14786 P00533 P05106 P05556 P06756 P08514 P08648 P13591 P19784 P27361 P28482 P32004 P36507 P52735 P63000 P67870 P68400 Q02750 Q13153 Q13797	CAML1 CK2A1 CK2A2 CK2N CSNK2A1 CSNK2A2 CSNK2B EGFR ERBB ERBB1 ERK1 ERK2 FNRA FNRB G5A GP2B GP3A HER1 ITGA2B ITGA5 ITGA9 ITGAB ITGAV ITGB1 ITGB3 L1CAM MAP2K1 MAP2K2 MAPK1 MAPK3 MDF2 MEK1 MEK2 MIC5 MKK2 MSK12 MSK8 NCAM NCAM1 NRP NRP1 PAK1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAC1 TC25 VAV2 VEGF165R VNRA VTNR	Homo sapiens (human)
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK and LTK ligand 1 ALK and LTK ligand 2 ALK tyrosine kinase receptor Fibroblast growth factor receptor substrate 2 Insulin receptor substrate 1 Midkine Myc proto-oncogene protein N-myc proto-oncogene protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Pleiotrophin Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK3 Tyrosine-protein phosphatase non-receptor type 6	O00459 P01106 P04198 P19174 P21246 P21741 P27986 P29350 P35568 P40763 P42336 P42338 P52333 Q6UX46 Q6UXT8 Q8WU20 Q9UM73	ALK ALKAL1 ALKAL2 APRF BHLHE37 BHLHE39 FAM150A FAM150B FRS2 GRB1 HBNF1 HCP IRS1 JAK3 MDK MK1 MYC MYCN NEGF1 NEGF2 NMYC PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTN PTP1C PTPN6 STAT3	Homo sapiens (human)
Signaling by ALK fusions and activated point mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK tyrosine kinase receptor B-cell lymphoma/leukemia 11A Baculoviral IAP repeat-containing protein 6 Bifunctional purine biosynthesis protein ATIC Cellular tumor antigen p53 Clathrin heavy chain 1 Cyclin-dependent kinase inhibitor 1 Cysteine--tRNA ligase, cytoplasmic Dynactin subunit 1 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF213 Echinoderm microtubule-associated protein-like 4 Elongation factor 1-gamma Eukaryotic translation initiation factor 2-alpha kinase 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibronectin GRIP and coiled-coil domain-containing protein 2 Growth factor receptor-bound protein 2 Huntingtin-interacting protein 1 Induced myeloid leukemia cell differentiation protein Mcl-1 Insulin receptor substrate 1 Interleukin-10 Interleukin-22 Kinesin light chain 1 Kinesin-1 heavy chain LIM domain only protein 7 Liprin-beta-1 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Moesin Myosin-9 Non-receptor tyrosine-protein kinase TYK2 Nucleophosmin Nucleoprotein TPR Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Polyubiquitin-B Polyubiquitin-C Protein TFG Protein phosphatase 1B Protein transport protein Sec31A Ribosome-binding protein 1 Sequestosome-1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Striatin Transcription factor Jun Tropomyosin alpha-3 chain Tropomyosin alpha-4 chain Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vinculin WD repeat and coiled-coil-containing protein cAMP-dependent protein kinase type I-alpha regulatory subunit	O00291 O00459 O43559 O43815 O75688 O94979 P02751 P04637 P05412 P06748 P06753 P0CG47 P0CG48 P10644 P12270 P18206 P19174 P22301 P26038 P26641 P27986 P29597 P31939 P33176 P35568 P35579 P38936 P40763 P42224 P42336 P42338 P45983 P45984 P49589 P49792 P62979 P62987 P62993 P67936 Q00610 Q00987 Q07820 Q07866 Q13501 Q14203 Q63HN8 Q86W92 Q8IWJ2 Q8WU20 Q8WWI1 Q92734 Q9GZX6 Q9H165 Q9H6R7 Q9HC35 Q9NR09 Q9NZJ5 Q9P2E9 Q9UM73	ALK ALO17 APRF ASH ATIC BCL11A BCL2L3 BIRC6 C17orf27 C2orf2 C2orf44 CAP20 CARS CARS1 CDKN1 CDKN1A CIP1 CLH17 CLTC CLTCL2 CTIP1 DCTN1 EEF1G EF1G EIF2AK3 EMAPL4 EML4 EVI9 FBX20 FBXO20 FN FN1 FRS2 FRS3 GCC2 GRB1 GRB2 HIP1 IL10 IL22 ILTIF IRS1 JNK1 JNK2 JUN KIAA0034 KIAA0336 KIAA0858 KIAA0905 KIAA1230 KIAA1289 KIAA1398 KIAA1554 KIAA1618 KIAA1809 KIF5B KLC KLC1 KNS KNS1 KNS2 LMO7 MAPK8 MAPK9 MCL1 MDA6 MDM2 MSN MYH9 MYSTR NPM NPM1 NUP358 ORCA OSIL P53 PEK PERK PIC1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PKR1 PLC1 PLCG1 PP2CB PPFIBP1 PPM1B PRKAR1 PRKAR1A PRKM8 PRKM9 PURH RANBP2 RANBP2L4 RNF213 RPS27A RRBP1 SAPK1 SAPK1A SAPK1C SDI1 SEC31A SEC31L1 SQSTM1 STAT1 STAT3 STRN TFG TP53 TPM3 TPM4 TPR TSE1 TYK2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCL WAF1 WDCP ZCYTO18 ZNF856	Homo sapiens (human)
Signaling by Activin	Activin receptor type-1B Activin receptor type-1C Activin receptor type-2A Activin receptor type-2B Dr1-associated corepressor Forkhead box protein H1 Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Transforming growth factor beta receptor type 3	O75593 P05111 P08476 P09529 P27037 P27361 P28482 P36896 P84022 Q03167 Q13485 Q13705 Q14919 Q15796 Q8NER5	ACVR1B ACVR1C ACVR2 ACVR2A ACVR2B ACVRLK4 ALK4 ALK7 DPC4 DRAP1 ERK1 ERK2 FAST1 FAST2 FOXH1 INHA INHBA INHBB MADH2 MADH3 MADH4 MADR2 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 SMAD2 SMAD3 SMAD4 TGFBR3	Homo sapiens (human)
Signaling by BMP	Activin receptor type-1-like Activin receptor type-2A Activin receptor type-2B Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein receptor type-1A Bone morphogenetic protein receptor type-1B Bone morphogenetic protein receptor type-2 Cerberus Chordin-like protein 1 E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Follistatin-related protein 1 Gremlin-2 Growth/differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog 6 Mothers against decapentaplegic homolog 7 Mothers against decapentaplegic homolog 9 Muellerian-inhibiting factor Noggin Ski oncogene Transforming growth factor beta receptor type 3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D3 Zinc finger FYVE domain-containing protein 16	O00238 O15105 O15198 O43541 O95393 O95813 P03971 P05111 P08476 P12643 P12755 P27037 P36894 P37023 P51668 P61077 Q03167 Q12841 Q13253 Q13485 Q13705 Q13873 Q15797 Q16671 Q7Z3T8 Q99717 Q9BU40 Q9H772 Q9HAU4 Q9HCE7 Q9UK05	ACVR2 ACVR2A ACVR2B ACVRL1 ACVRLK1 ACVRLK3 ALK1 ALK3 AMH AMHR AMHR2 BMP10 BMP2 BMP2A BMP9 BMPR1A BMPR1B BMPR2 BSP1 CER1 CHRDL1 CKTSF1B2 DAND3 DAND4 DPC4 FRP FSTL1 GDF2 GREM2 INHA INHBA KIAA0305 KIAA1625 MADH1 MADH4 MADH5 MADH6 MADH7 MADH8 MADH9 MADR1 MIF MISR2 NOG NRLN1 PPH1 PRDC SFT SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD8 SMAD9 SMURF1 SMURF2 TGFBR3 UBC5A UBC5C UBCH5 UBCH5A UBCH5C UBE2D1 UBE2D3 ZFYVE16	Homo sapiens (human)
Signaling by BRAF and RAF1 fusions	14-3-3 protein beta/alpha A-kinase anchor protein 9 AP-3 complex subunit beta-1 Acylglycerol kinase, mitochondrial Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Angiogenic factor with G patch and FHA domains 1 Bcl-2-like protein 11 Beta-arrestin-1 Beta-arrestin-2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epithelial splicing regulatory protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas H(+)/Cl(-) exchange transporter 6 Integrin alpha-IIb Integrin beta-3 KH domain-containing RNA-binding protein QKI Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 Lysine-specific demethylase 7A MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin phosphatase Rho-interacting protein Phosphatidylethanolamine-binding protein 1 Prelamin-A/C Protein FAM114A2 Protein FAM131B Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase RNA-binding protein FXR1 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Staphylococcal nuclease domain-containing protein 1 Talin-1 Terminal nucleotidyltransferase 4A Trafficking kinesin-binding protein 1 Transcription intermediary factor 1-alpha Type-1 angiotensin II receptor-associated protein Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 UPF0606 protein KIAA1549 Ubiquitin-like modifier-activating enzyme ATG7 Vinculin Zinc finger CCCH-type antiviral protein 1 von Willebrand factor	O00203 O15164 O43252 O43521 O60674 O95352 P01111 P01112 P02545 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P51114 P51797 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q53H12 Q5XG87 Q6NXG1 Q6RW13 Q6VAB6 Q6WCQ1 Q6ZMT4 Q7KZF4 Q7Z2W4 Q7Z5R6 Q86XD5 Q8IVT5 Q8N302 Q8WXI2 Q969H4 Q96PU8 Q99996 Q9HCM3 Q9NRY5 Q9UPV9 Q9UQM7 Q9Y490	ADTB3A AGGF1 AGK AGTRAP AKAP350 AKAP450 AKAP9 AP3B1 APBB1IP APG7L ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 ATG7 ATPSK1 ATRAP BCL2L11 BIM BRAF BRAF1 C5orf3 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CLCN6 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 ESRP1 F8VWF FAM114A2 FAM131B FGA FGB FGG FN FN1 FXR1 GP2B GP3A GPATC7 GPATCH7 HKQ HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 JHDM1D KDM7 KDM7A KIAA0046 KIAA0051 KIAA0773 KIAA0803 KIAA0864 KIAA0902 KIAA0968 KIAA1027 KIAA1042 KIAA1549 KIAA1718 KREV1 KSR KSR1 KSR2 LMN1 LMNA MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MPRIP MRIP MULK NRAS OIP106 PAPD7 PAPSS PAPSS1 PBP PEBP PEBP1 PKS PKS2 POLS PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 QKI RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RBM35A RHOIP3 RIAM RNF82 SND1 SRC SRC1 TDRD11 TENT4A TIF1 TIF1A TLN TLN1 TRAK1 TRF4 TRIM24 VCL VG5Q VWF YWHAB ZC3HAV1 ZC3HDC2	Homo sapiens (human)
Signaling by CSF1 (M-CSF) in myeloid cells	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 E3 ubiquitin-protein ligase CBL GRB2-associated-binding protein 2 GRB2-associated-binding protein 3 GRB2-related adapter protein 2 GTPase KRas Interleukin-34 Macrophage colony-stimulating factor 1 receptor Macrophage colony-stimulating factor 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Polyubiquitin-B Polyubiquitin-C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Son of sevenless homolog 1 THO complex subunit 5 Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00329 O15357 O75791 P01116 P06241 P07333 P07947 P07948 P08631 P09603 P0CG47 P0CG48 P12931 P16885 P22681 P27986 P29353 P40763 P42224 P42336 P42338 P62979 P62987 Q06124 Q07889 Q13769 Q6ZMJ4 Q8WWW8 Q92835 Q9UQC2	APRF C16orf77 C22orf19 CBL CBL2 CSF1 CSF1R FMS FYN GAB2 GAB3 GADS GRAP2 GRB1 GRB2L GRID HCK IL34 INPP5D INPPL1 JTK8 KIAA0571 KIAA0983 KRAS KRAS2 LYN PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PLCG2 PTP2C PTPN11 RASK2 RNF55 RPS27A SHC SHC1 SHCA SHIP SHIP1 SHIP2 SHPTP2 SOS1 SRC SRC1 STAT1 STAT3 THOC5 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YES YES1	Homo sapiens (human)

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