GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1776 - 1800** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
Astrocytic Glutamate-Glutamine Uptake And Metabolism	Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Glutamine synthetase Sodium-coupled neutral amino acid symporter 1	P15104 P43003 P43004 Q9H2H9	ATA1 EAAT1 EAAT2 GLAST GLAST1 GLNS GLT1 GLUL NAT2 SAT1 SLC1A2 SLC1A3 SLC38A1 SNAT1	Homo sapiens (human)
Inhibition of replication initiation of damaged DNA by RB1/E2F1	DNA polymerase alpha catalytic subunit DNA polymerase alpha subunit B DNA primase large subunit DNA primase small subunit Retinoblastoma-associated protein Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1	P06400 P09884 P30153 P30154 P49642 P49643 P62714 P67775 Q01094 Q14181 Q14186 Q14188 Q9Y5P8	DP1 DP2 E2F1 POLA POLA1 POLA2 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R3B PPP2R3L PRIM1 PRIM2 PRIM2A RB1 RBBP3 TFDP1 TFDP2	Homo sapiens (human)
Defective MAOA causes BRUNS	Amine oxidase [flavin-containing] A	P21397	MAOA	Homo sapiens (human)
Defective RIPK1-mediated regulated necrosis	Caspase-8 FAS-associated death domain protein Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor receptor type 1-associated DEATH domain protein	Q12933 Q13158 Q13546 Q14790 Q15628	CASP8 FADD MCH5 MORT1 RIP RIP1 RIPK1 TRADD TRAF2 TRAP3	Homo sapiens (human)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	CREB-binding protein Catenin beta-1 Histone acetyltransferase p300 Interferon regulatory factor 3 Leucine-rich repeat flightless-interacting protein 1	P35222 Q09472 Q14653 Q32MZ4 Q92793	CBP CREBBP CTNNB CTNNB1 EP300 GCF2 IRF3 LRRFIP1 P300 TRIP	Homo sapiens (human)
Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25)	Vesicular glutamate transporter 3	Q8NDX2	SLC17A8 VGLUT3	Homo sapiens (human)
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Long-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P28330 P30084 P40939 P55084 Q16836	ACADL ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC SCHAD	Homo sapiens (human)
ER-Phagosome pathway	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Antigen peptide transporter 1 Antigen peptide transporter 2 Beta-2-microglobulin Calreticulin Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain HLA class I histocompatibility antigen, A alpha chain HLA class I histocompatibility antigen, B alpha chain HLA class I histocompatibility antigen, C alpha chain HLA class I histocompatibility antigen, alpha chain E HLA class I histocompatibility antigen, alpha chain F HLA class I histocompatibility antigen, alpha chain G High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Lymphocyte antigen 96 Major outer membrane protein P.IB Monocyte differentiation antigen CD14 Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator Peptidyl-prolyl cis-trans isomerase Mip Platelet glycoprotein 4 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein S100-A1 Protein S100-A8 Protein S100-A9 Protein disulfide-isomerase A3 Protein transport protein Sec61 subunit alpha isoform 1 Protein transport protein Sec61 subunit alpha isoform 2 Protein transport protein Sec61 subunit beta Protein transport protein Sec61 subunit gamma Putative HLA class I histocompatibility antigen, alpha chain H Synaptosomal-associated protein 23 Syntaxin-4 Tapasin Toll-like receptor 1 Toll-like receptor 2 Toll-like receptor 4 Toll-like receptor 6 Toll/interleukin-1 receptor domain-containing adapter protein Tyrosine-protein kinase BTK Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 8 Vesicle-trafficking protein SEC22b	O00161 O00206 O00231 O00232 O00487 O14818 O14920 O15111 O15533 O43242 O60603 O75396 P01889 P01893 P02671 P02675 P02679 P04439 P05109 P06702 P08571 P09429 P0CG47 P0CG48 P10321 P13747 P16671 P17693 P17980 P20618 P23297 P25786 P25787 P25788 P25789 P26623 P27797 P28066 P28070 P28072 P28074 P30101 P30511 P30690 P35998 P43686 P48556 P49720 P49721 P51665 P58753 P60059 P60468 P60896 P60900 P61619 P61769 P62191 P62195 P62333 P62979 P62987 Q03518 Q03519 Q06187 Q12846 Q13200 Q15008 Q15399 Q15836 Q16186 Q99436 Q99460 Q99836 Q9BV40 Q9H9S3 Q9UNM6 Q9Y2C9 Q9Y6K9 Q9Y6Y9	ABCB2 ABCB3 ADRM1 AGMX1 ATK B2M BPK BTK C7orf76 CAGA CAGB CALR CD14 CD36 CFAG CHUK CRTC DSS1 ERP57 ERP60 ESOP1 FGA FGB FGG FIP3 GP110 GP3B GP4 GRP58 HC2 HC3 HC8 HC9 HLA-5.4 HLA-6.0 HLA-6.2 HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HLA-H HLAA HLAB HLAC HLAE HLAF HLAG HLAH HMG1 HMGB1 HSPC IKBKB IKBKG IKKA IKKB KIAA0012 KIAA0107 LMPX LMPY LY96 MAL MB1 MD2 MIP224 MOV34L MRP14 MRP8 MSS1 MYD88 NEMO NGS17 NU PDIA3 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSF1 PSF2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RING11 RING4 RPS27A S100A S100A1 S100A8 S100A9 SEC22B SEC22L1 SEC61A SEC61A1 SEC61A2 SEC61B SEC61G SEM1 SHFDG1 SHFM1 SNAP23 STX4 STX4A SUG1 SUG2 SYB3 TAP1 TAP2 TAPA TAPBP TBP1 TBP7 TCF16 TIL4 TIRAP TLR1 TLR2 TLR4 TLR6 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VAMP3 VAMP8 X Y Y1 Y3 Z mip porB	Homo sapiens (human)
Ovarian tumor domain proteases	Adenomatous polyposis coli protein Antiviral innate immune response receptor RIG-I Cellular tumor antigen p53 Cyclin-dependent kinase 1 Deubiquitinating protein VCPIP1 E3 ubiquitin-protein ligase RNF128 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Estrogen receptor Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator Nucleotide-binding oligomerization domain-containing protein 1 Nucleotide-binding oligomerization domain-containing protein 2 OTU domain-containing protein 3 OTU domain-containing protein 5 OTU domain-containing protein 7A OTU domain-containing protein 7B Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Polyubiquitin-B Polyubiquitin-C Receptor-interacting serine/threonine-protein kinase 1 Receptor-interacting serine/threonine-protein kinase 2 TNF receptor-associated factor 3 TNF receptor-associated factor 6 TNFAIP3-interacting protein 1 TNFAIP3-interacting protein 2 TNFAIP3-interacting protein 3 Transforming protein RhoA Transitional endoplasmic reticulum ATPase Tumor necrosis factor alpha-induced protein 3 Ubiquitin thioesterase OTU1 Ubiquitin thioesterase OTUB1 Ubiquitin thioesterase OTUB2 Ubiquitin thioesterase ZRANB1 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43353 O95786 P03372 P04637 P06493 P0CG47 P0CG48 P21580 P25054 P51668 P55072 P60484 P61586 P62979 P62987 Q13114 Q13546 Q14258 Q15025 Q5T2D3 Q5VVQ6 Q6GQQ9 Q7Z434 Q8IUD6 Q8NFZ5 Q8TE49 Q8TEB7 Q96DC9 Q96FW1 Q96G74 Q96JH7 Q96KP6 Q9BYX4 Q9C037 Q9HC29 Q9UGI0 Q9Y239 Q9Y4K3 Q9Y6K9	ABIN2 ABIN3 APC ARH12 ARHA C14orf137 C15orf16 CAP-1 CARD15 CARD4 CARDIAK CDC2 CDC28A CDK1 CDKN1 CEZANNE2 CRAF1 DDX58 DP2.5 DUBA8 EFP ESR ESR1 FIP3 FLIP1 HEL-220 HEL-S-70 HIN7 IFIH1 IKBKG IPS1 KIAA0113 KIAA0459 KIAA1271 KIAA1850 LIND MAVS MDA5 MMAC1 NAF1 NEMO NOD1 NOD2 NR3A1 OTB1 OTB2 OTU1 OTU2 OTUB1 OTUB2 OTUD2 OTUD3 OTUD5 OTUD7 OTUD7A OTUD7B OTUD7C P34CDC2 P53 PTEN RH116 RHO12 RHOA RICK RIGI RIP RIP1 RIP2 RIPK1 RIPK2 RNF128 RNF135 RNF147 RNF85 RNF87 RPS27A SFT TEP1 TNFAIP3 TNIP1 TNIP2 TNIP3 TP53 TRABID TRAF3 TRAF6 TRAFAMN TRIM25 TRIM4 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH5 UBCH5A UBE2D1 VCIP135 VCP VCPIP1 VISA YOD1 ZA20D1 ZNF147 ZRANB1	Homo sapiens (human)
NTF3 activates NTRK3 signaling	NT-3 growth factor receptor Neurotrophin-3	P20783 Q16288	NTF3 NTRK3 TRKC	Homo sapiens (human)
Beta oxidation of butanoyl-CoA to acetyl-CoA	Acyl-coenzyme A synthetase ACSM3, mitochondrial Acyl-coenzyme A synthetase ACSM6, mitochondrial Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Short-chain specific acyl-CoA dehydrogenase, mitochondrial	P16219 P30084 Q16836 Q53FZ2 Q6P461	ACADS ACSM3 ACSM6 C10orf129 ECHS1 HAD HAD1 HADH HADHSC SAH SCHAD	Homo sapiens (human)
Defective GALNT3 causes HFTC	Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1 Polypeptide N-acetylgalactosaminyltransferase 3	P15941 P98088 Q02505 Q02817 Q14435 Q5SSG8 Q685J3 Q6W4X9 Q7Z5P9 Q8N307 Q8N387 Q8TAX7 Q8WXI7 Q96DR8 Q99102 Q9H195 Q9H3R2 Q9HC84 Q9UKN1	C6orf205 CA125 DRCC1 GALNT3 KIAA1359 MG2 MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 PUM RECC SBEM SMUC	Homo sapiens (human)
Signal attenuation	Growth factor receptor-bound protein 10 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 Son of sevenless homolog 1	P01308 P06213 P27361 P28482 P29353 P35568 Q07889 Q13322 Q9Y4H2	ERK1 ERK2 GRB10 GRBIR INS INSR IRS1 IRS2 KIAA0207 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 SHC SHC1 SHCA SOS1	Homo sapiens (human)
Activated NTRK2 signals through FYN	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Glutamate receptor ionotropic, NMDA 2B Proto-oncogene tyrosine-protein kinase Src	P12931 P23560 Q13224 Q16620	BDNF GRIN2B NMDAR2B NTRK2 SRC SRC1 TRKB	Homo sapiens (human)
NOTCH1 Intracellular Domain Regulates Transcription	CREB-binding protein Cullin-1 Cyclin-C Cyclin-dependent kinase 8 E3 ubiquitin-protein ligase RBX1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Hairy/enhancer-of-split related with YRPW motif-like protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase p300 Histone deacetylase 11 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 6 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9 Hypoxia-inducible factor 1-alpha Mastermind-like domain-containing protein 1 Mastermind-like protein 1 Mastermind-like protein 2 Mastermind-like protein 3 Myc proto-oncogene protein Neurobeachin Neurogenic locus notch homolog protein 1 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Polyamine deacetylase HDAC10 Polyubiquitin-B Polyubiquitin-C Recombining binding protein suppressor of hairless S-phase kinase-associated protein 1 SNW domain-containing protein 1 Transcription factor HES-1 Transcription factor HES-5 Transducin-like enhancer protein 1 Transducin-like enhancer protein 2 Transducin-like enhancer protein 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15379 O60907 O75376 P01106 P0CG47 P0CG48 P24863 P46531 P49336 P56524 P62877 P62979 P62987 P63208 Q04724 Q04725 Q04727 Q06330 Q09472 Q13495 Q13547 Q13573 Q13616 Q14469 Q16665 Q5TA89 Q8IZL2 Q8NFP9 Q8WUI4 Q92585 Q92769 Q92793 Q92830 Q92831 Q969S8 Q96DB2 Q96JK9 Q9BY41 Q9BZK7 Q9NQ87 Q9UBN7 Q9UBP5 Q9UKV0 Q9UQL6 Q9Y5J3 Q9Y618	BCL8B BHLHB31 BHLHB32 BHLHB33 BHLHB38 BHLHB39 BHLHE39 BHLHE78 CBP CCNC CDK8 CG1 CHF1 CHF2 CREBBP CTG26 CUL1 CXorf6 EMC19 EP300 GCN5 GCN5L2 GRG4 GRL HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC7A HDAC7B HDAC8 HDAC9 HDACL1 HDRP HERP HERP1 HERP2 HES1 HES5 HESR1 HEY1 HEY2 HEYL HIF1A HL HRT1 HRT2 HRT3 HRY IGKJRB IGKJRB1 IRA1 KAT2A KAT2B KIAA0200 KIAA0288 KIAA0600 KIAA0744 KIAA0901 KIAA1047 KIAA1261 KIAA1544 KIAA1816 KIAA1819 LYST2 MAML1 MAML2 MAML3 MAMLD1 MITR MOP1 MYC NBEA NCOR1 NCOR2 NOTCH1 OCP2 P300 PASD8 PCAF RBPJ RBPJK RBPSUH RBX1 RNF75 ROC1 RPD3L1 RPS27A SKIIP SKIP SKP1 SKP1A SNW1 TAN1 TBL1 TBL1X TBL1XR1 TBLR1 TCEB1L TLE1 TLE2 TLE4 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Signaling by FGFR2 fusions	Fibroblast growth factor receptor 2	P21802	BEK FGFR2 KGFR KSAM	Homo sapiens (human)
IRAK2 mediated activation of TAK1 complex	Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 7 Polyubiquitin-B Polyubiquitin-C TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 TNF receptor-associated factor 6 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O43187 O43318 P0CG47 P0CG48 P62979 P62987 Q15750 Q8N5C8 Q9NYJ8 Q9Y4K3	IRAK2 KIAA0733 MAP3K7 MAP3K7IP1 MAP3K7IP2 MAP3K7IP3 RNF85 RPS27A TAB1 TAB2 TAB3 TAK1 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Translation initiation complex formation	Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic translation initiation factor 1A, X-chromosomal Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E Eukaryotic translation initiation factor 4H Polyadenylate-binding protein 1 Ribosomal protein eS27-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00303 O15371 O15372 O75821 O75822 P05198 P06730 P08708 P08865 P11940 P15880 P20042 P22090 P23396 P23588 P25398 P39019 P41091 P42677 P46781 P46782 P46783 P47813 P55884 P60228 P60842 P60866 P61247 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62701 P62753 P62841 P62847 P62851 P62854 P62857 P62861 P62979 P63220 Q04637 Q13347 Q14152 Q14240 Q15056 Q71UM5 Q7L2H7 Q8TD47 Q99613 Q9UBQ5 Q9Y262	CCG2 D6S218E DDX2A DDX2B EIF1A EIF1AX EIF2A EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 EIF3A EIF3B EIF3C EIF3D EIF3E EIF3EIP EIF3F EIF3G EIF3H EIF3I EIF3J EIF3K EIF3L EIF3M EIF3S1 EIF3S10 EIF3S12 EIF3S2 EIF3S3 EIF3S4 EIF3S5 EIF3S6 EIF3S6IP EIF3S7 EIF3S8 EIF3S9 EIF4A EIF4A1 EIF4A2 EIF4B EIF4C EIF4E EIF4EL1 EIF4F EIF4G EIF4G1 EIF4GI EIF4H FAU FTE1 HFLB5 INT6 KIAA0038 KIAA0139 LAMBR LAMR1 MFTL MPS1 PAB1 PABP PABP1 PABPC1 PABPC2 PCID1 RIG RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA SCAR TRIP1 UBA80 UBCEP1 WBSCR1 WSCR1	Homo sapiens (human)
Defective APRT disrupts adenine salvage	Adenine phosphoribosyltransferase	P07741	APRT	Homo sapiens (human)
Senescence-Associated Secretory Phenotype (SASP)	Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 CCAAT/enhancer-binding protein beta Cell division cycle protein 16 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 4 inhibitor C Cyclin-dependent kinase 4 inhibitor D Cyclin-dependent kinase 4 Cyclin-dependent kinase 6 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor 2A Fizzy-related protein homolog Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-lysine N-methyltransferase EHMT1 Histone-lysine N-methyltransferase EHMT2 Homeobox protein VENTX Insulin-like growth factor-binding protein 7 Interleukin-1 alpha Interleukin-6 Interleukin-8 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Protein c-Fos Ribosomal protein S6 kinase alpha-1 Ribosomal protein S6 kinase alpha-2 Ribosomal protein S6 kinase alpha-3 Signal transducer and activator of transcription 3 Transcription factor Jun Transcription factor p65 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00762 O60814 O95231 P01100 P01583 P04908 P05231 P05412 P06899 P0C5Y9 P0CG47 P0CG48 P10145 P11802 P16104 P17676 P19838 P20248 P20671 P23527 P24941 P27361 P28482 P30260 P33778 P38936 P40763 P42771 P42772 P42773 P46527 P51668 P51812 P51965 P55273 P57053 P58876 P60006 P62805 P62807 P62979 P62987 P68431 P78396 P84243 Q00534 Q04206 Q13042 Q13164 Q15349 Q15418 Q16270 Q16763 Q16777 Q16778 Q6FI13 Q71DI3 Q71UI9 Q8N257 Q8NHZ8 Q93077 Q93079 Q96A08 Q96DE5 Q96KQ7 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9H1A4 Q9H9B1 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13	ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 APRF BAT8 BMK1 C10orf104 C11orf51 C6orf30 C9orf17 CAP20 CCN1 CCNA CCNA1 CCNA2 CDC16 CDC23 CDC26 CDC27 CDH1 CDK2 CDK4 CDK6 CDKN1 CDKN1A CDKN1B CDKN2 CDKN2A CDKN2B CDKN2C CDKN2D CDKN6 CEBPB CENP-27 CIP1 CXCL8 D0S1430E D17S978E E2EPF EHMT1 EHMT2 ERK1 ERK2 ERK5 EUHMTASE1 FOS FYR FZR FZR1 G0S7 G9A GLP H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HPX42B IFNB2 IGFBP7 IL1A IL1F1 IL6 IL8 ISPK1 JUN KIAA1242 KIAA1406 KIAA1876 KIP1 KMT1C KMT1D MAC25 MAPK1 MAPK3 MAPK7 MAPKAPK1A MAPKAPK1B MAPKAPK1C MDA6 MTS1 MTS2 NFKB1 NFKB3 NG36 PIC1 PRKM1 PRKM2 PRKM3 PRKM7 PSF RELA RPS27A RPS6KA1 RPS6KA2 RPS6KA3 RSK1 RSK2 RSK3 SDI1 SFT STAT3 TCF5 TSG24 TSH2B UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S VENTX VENTX2 WAF1 p27	Homo sapiens (human)
2-LTR circle formation	Barrier-to-autointegration factor DNA ligase 4 DNA repair protein XRCC4 Gag polyprotein Gag-Pol polyprotein High mobility group protein HMG-I/HMG-Y PC4 and SFRS1-interacting protein Protein Rev Protein Vpr Protein Vpu Virion infectivity factor X-ray repair cross-complementing protein 5 X-ray repair cross-complementing protein 6	O75475 O75531 P04585 P04591 P04618 P05919 P12956 P13010 P17096 P49917 P69723 P69726 Q13426	BAF BANF1 BCRG1 DFS70 G22P1 G22P2 HMGA1 HMGIY LEDGF LIG4 PSIP1 PSIP2 XRCC4 XRCC5 XRCC6 gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Cleavage of the damaged purine	Adrenocortical dysplasia protein homolog DNA-3-methyladenine glycosylase Endonuclease 8-like 3 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H4 N-glycosylase/DNA lyase Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	O15527 O60814 P04908 P06899 P0C5Y9 P16104 P20671 P23527 P29372 P33778 P54274 P57053 P58876 P62805 P62807 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q8TAT5 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0	AAG ACD ANPG DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-4 H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 MID1 MMH MPG MUTM NEIL3 OGG1 OGH1 PIN2 PIP1 POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B	Homo sapiens (human)
Sodium-coupled phosphate cotransporters	Sodium-dependent phosphate transporter 1 Sodium-dependent phosphate transporter 2	Q08357 Q8WUM9	GLVR1 GLVR2 PIT1 PIT2 SLC20A1 SLC20A2	Homo sapiens (human)
LDL remodeling	Apolipoprotein B-100 Apolipoprotein F Apolipoprotein(a) Cholesteryl ester transfer protein Microsomal triglyceride transfer protein large subunit Protein disulfide-isomerase	P04114 P07237 P08519 P11597 P55157 Q13790	APOB APOF CETP ERBA2L LPA MTP MTTP P4HB PDI PDIA1 PO4DB	Homo sapiens (human)
Resolution of Sister Chromatid Cohesion	Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 20 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cohesin subunit SA-1 Cohesin subunit SA-2 Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Double-strand-break repair protein rad21 homolog Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 FIGNL1-interacting regulator of recombination and mitosis G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 SKA complex subunit 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Small ribosomal subunit protein eS27 Sororin Spindle and kinetochore-associated protein 2 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Wings apart-like protein homolog ZW10 interactor	O00139 O14576 O14777 O14980 O15392 O43237 O43264 O43683 O43684 O60216 O60566 O75122 O95067 O95229 P06493 P14635 P30153 P30154 P30622 P36873 P42677 P43034 P46060 P49450 P49454 P49792 P50748 P53350 P55735 P57740 P62714 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14683 Q14738 Q15172 Q15173 Q15691 Q16537 Q29RF7 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q7Z5K2 Q8N0S6 Q8N2Z9 Q8N3U4 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NI77 Q8WUM0 Q8WVK7 Q8WVM7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96EA4 Q96FF9 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSG2 Q9NSP4 Q9NTI5 Q9NXR1 Q9P258 Q9UQE7 Q9Y266 Q9Y6D9 Q9Y6G9	AHCTF1 AIK2 AIM1 AIRK2 API4 APITD1 APOLO1 APRIN ARK2 AS3 AURKB B9D2 BAM BIRC5 BMH BUB1 BUB1B BUB1L BUB3 BUBR1 C16orf56 C16orf60 C18orf24 C1orf112 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 CASC5 CCDC99 CCNB CCNB1 CCNB2 CDC2 CDC20 CDC28A CDCA1 CDCA5 CDCA8 CDK1 CDKN1 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CSPG6 CYLN1 D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DXS423E DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ELYS EOPA ERCC6L FAAP16 FAM33A FIRRM FOE FSHPRH1 HDLC1 HEC HEC1 HR21 IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0078 KIAA0097 KIAA0166 KIAA0178 KIAA0197 KIAA0261 KIAA0325 KIAA0622 KIAA0627 KIAA0648 KIAA0979 KIAA1361 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MCM21R MDCR MDS MHF1 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MPS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 NXP1 P34CDC2 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PDS5 PDS5A PDS5B PESCRG3 PICH PLK PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RAD21 RANBP2 RANGAP1 RCC2 ROD RPS27 RSN SA1 SA2 SB1.8 SCC1 SCC3 SD SEC13 SEC13A SEC13L1 SEC13R SGO1 SGO2 SGOL1 SGOL2 SKA1 SKA2 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STAG1 STAG2 STK1 STK12 STK5 TAOK1 TD60 TMBS62 TXBP181 WAPAL WAPL XPO1 ZW10 ZWILCH ZWINT	Homo sapiens (human)

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