GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Defective GALNT3 causes HFTC	Mucin-12 Mucin-13 Mucin-15 Mucin-16 Mucin-17 Mucin-19 Mucin-1 Mucin-20 Mucin-21 Mucin-2 Mucin-3A Mucin-3B Mucin-4 Mucin-5AC Mucin-5B Mucin-6 Mucin-7 Mucin-like protein 1 Polypeptide N-acetylgalactosaminyltransferase 3	P15941 P98088 Q02505 Q02817 Q14435 Q5SSG8 Q685J3 Q6W4X9 Q7Z5P9 Q8N307 Q8N387 Q8TAX7 Q8WXI7 Q96DR8 Q99102 Q9H195 Q9H3R2 Q9HC84 Q9UKN1	C6orf205 CA125 DRCC1 GALNT3 KIAA1359 MG2 MUC1 MUC11 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC2 MUC20 MUC21 MUC3 MUC3A MUC3B MUC4 MUC5 MUC5AC MUC5B MUC6 MUC7 MUCL1 PUM RECC SBEM SMUC	Homo sapiens (human)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	Acetylcholine receptor subunit delta Acetylcholine receptor subunit epsilon Acetylcholine receptor subunit gamma Neuronal acetylcholine receptor subunit alpha-3 Neuronal acetylcholine receptor subunit alpha-4 Neuronal acetylcholine receptor subunit beta-2 Neuronal acetylcholine receptor subunit beta-4	P07510 P17787 P30926 P32297 P43681 Q04844 Q07001	ACHRD ACHRE ACHRG CHRNA3 CHRNA4 CHRNB2 CHRNB4 CHRND CHRNE CHRNG NACHRA3 NACRA4	Homo sapiens (human)
Biosynthesis of EPA-derived SPMs	Prostaglandin G/H synthase 2	P35354	COX2 PTGS2	Homo sapiens (human)
Mitotic Prometaphase	Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 20 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 SKA complex subunit 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 2 ZW10 interactor	O00139 O14576 O14777 O14980 O15392 O43237 O43264 O43683 O43684 O60566 O75122 O95229 P30153 P30154 P30622 P36873 P42677 P43034 P46060 P49450 P49454 P49792 P50748 P53350 P55735 P57740 P62714 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14738 Q15172 Q15173 Q15691 Q16537 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q8N0S6 Q8N2Z9 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NI77 Q8WUM0 Q8WVK7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96EA4 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NXR1 Q9P258 Q9Y266 Q9Y6D9 Q9Y6G9	AHCTF1 AIK2 AIM1 AIRK2 API4 APITD1 ARK2 AURKB B9D2 BIRC5 BUB1 BUB1B BUB1L BUB3 BUBR1 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 CASC5 CCDC99 CDC20 CDCA1 CDCA8 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CYLN1 D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ELYS EOPA ERCC6L FAAP16 FAM33A FSHPRH1 HDLC1 HEC HEC1 IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0097 KIAA0166 KIAA0197 KIAA0325 KIAA0622 KIAA0627 KIAA1361 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MCM21R MDCR MDS MHF1 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MPS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PESCRG3 PICH PLK PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E RANBP2 RANGAP1 RCC2 ROD RPS27 RSN SD SEC13 SEC13A SEC13L1 SEC13R SGO1 SGO2 SGOL1 SGOL2 SKA1 SKA2 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STK1 STK12 STK5 TAOK1 TD60 TMBS62 TXBP181 XPO1 ZW10 ZWILCH ZWINT	Homo sapiens (human)
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin-3 Drebrin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoproteins C1/C2 Hsp90 co-chaperone Cdc37 PH-interacting protein RNA-binding motif protein, X chromosome RNA-binding protein Musashi homolog 2 Rho-related BTB domain-containing protein 2 Serine/arginine repetitive matrix protein 1 Serine/threonine-protein kinase 38 Spliceosome RNA helicase DDX39B T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin-like protein 1 Transformer-2 protein homolog beta Tropomodulin-3 Twinfilin-1 Unconventional myosin-VI	O43396 P07900 P07910 P08238 P12814 P38159 P40227 P62995 P63261 P78371 Q12792 Q13618 Q13838 Q15208 Q16543 Q16643 Q8IYB3 Q8WWQ0 Q96DH6 Q99832 Q9BYZ6 Q9NYL9 Q9UM54	99D8.1 ACTG ACTG1 ACTN1 BAT1 CCT2 CCT6 CCT6A CCT7 CCTB CCTH CCTZ CDC37 CDC37A CUL3 D0S117E DBC2 DBN1 DCAF14 DDX39B HNRNPC HNRPC HNRPG HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0389 KIAA0617 KIAA0717 MSI2 MYO6 NDR1 NIP7-1 PHIP PTK9 RBMX RBMXP1 RHOBTB2 SFRS10 SRM160 SRRM1 STK38 TMOD3 TRA2B TRP32 TWF1 TXL TXNL TXNL1 UAP56 WDR11	Homo sapiens (human)
VLDLR internalisation and degradation	AP-2 complex subunit alpha-1 AP-2 complex subunit alpha-2 AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain 1 Clathrin light chain A E3 ubiquitin-protein ligase MYLIP Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Polyubiquitin-B Polyubiquitin-C Proprotein convertase subtilisin/kexin type 9 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Very low-density lipoprotein receptor	O94973 O95782 P09496 P0CG47 P0CG48 P53680 P55055 P62979 P62987 P63010 P98155 Q00610 Q13133 Q8NBP7 Q8WY64 Q96CW1	ADTAA ADTAB ADTB2 AP17 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 BZF1 CLAPA1 CLAPA2 CLAPB1 CLAPM1 CLAPS2 CLH17 CLTA CLTC CLTCL2 HIP9 HYPJ IDOL KIAA0034 KIAA0109 KIAA0899 LXRA LXRB MYLIP NARC1 NER NR1H2 NR1H3 PCSK9 RPS27A UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UNR VLDLR	Homo sapiens (human)
Nuclear signaling by ERBB4	Apolipoprotein E Arf-GAP with dual PH domain-containing protein 1 Beta-casein Disintegrin and metalloproteinase domain-containing protein 17 Estrogen receptor Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Glial fibrillary acidic protein Max dimerization protein 4 Nicastrin Nuclear receptor corepressor 1 Presenilin-1 Presenilin-2 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Progesterone receptor Proheparin-binding EGF-like growth factor Protein S100-B Proto-oncogene tyrosine-protein kinase Src SPARC Signal transducer and activator of transcription 5A Stathmin Stromal cell-derived factor 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 Transcriptional coactivator YAP1 WW domain-containing oxidoreductase	O14511 O14944 O75376 O75689 P02649 P03372 P04271 P05814 P06401 P09486 P12931 P14136 P16949 P35070 P42229 P46937 P48061 P49768 P49810 P56975 P78536 Q02297 Q14582 Q8WW43 Q8WWG1 Q92542 Q96BI3 Q99075 Q9NYJ8 Q9NZ42 Q9NZC7	AD3 AD4 ADAM17 ADAP1 APH1A APH1B APOE BHLHC12 BTC C1orf215 CASB CENTA1 CSN2 CSVP CXCL12 DTR DTS EREG ESR ESR1 FOR GFAP GGF HBEGF HEGFL HGL HRGA KIAA0253 KIAA0733 KIAA1047 LAP18 MAD4 MAP3K7IP2 MXD4 NCOR1 NCSTN NDF NR3A1 NR3C3 NRG1 NRG2 NRG3 NRG4 NTAK ON OP18 PEN2 PGR PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 S100B SDF1 SDF1A SDF1B SDR41C1 SMDF SPARC SRC SRC1 STAT5 STAT5A STM2 STMN1 TAB2 TACE WOX1 WWOX YAP1 YAP65	Homo sapiens (human)
Metabolism of polyamines	Ornithine decarboxylase S-adenosylmethionine decarboxylase proenzyme Spermidine synthase Spermine synthase	P11926 P17707 P19623 P52788	AMD AMD1 ODC1 SMS SPS1 SRM SRML1	Homo sapiens (human)
Astrocytic Glutamate-Glutamine Uptake And Metabolism	Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Glutamine synthetase Sodium-coupled neutral amino acid symporter 1	P15104 P43003 P43004 Q9H2H9	ATA1 EAAT1 EAAT2 GLAST GLAST1 GLNS GLT1 GLUL NAT2 SAT1 SLC1A2 SLC1A3 SLC38A1 SNAT1	Homo sapiens (human)
Signaling by FLT3 fusion proteins	Cyclin-dependent kinase inhibitor 1 GRB2-associated-binding protein 2 GTPase HRas GTPase NRas Golgin subfamily B member 1 NADPH oxidase 4 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Serine/threonine-protein kinase pim-1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Spectrin beta chain, non-erythrocytic 1 Thyroid receptor-interacting protein 11 Transcription factor ETV6 Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	P01111 P01112 P11309 P27986 P38936 P41212 P42229 P42336 P51692 Q01082 Q07889 Q14789 Q15643 Q92614 Q9NPH5 Q9UBW7 Q9UQC2	CAP20 CD245 CDKN1 CDKN1A CEV14 CIP1 ETV6 FIM GAB2 GOLGB1 GRB1 HRAS HRAS1 KIAA0216 KIAA0571 MDA6 MYO18A MYSPDZ NOX4 NRAS PIC1 PIK3CA PIK3R1 PIM1 RAMP RENOX SDI1 SOS1 SPTB2 SPTBN1 STAT5 STAT5A STAT5B TEL TEL1 TIAF1 TRIP11 WAF1 ZMYM2 ZNF198	Homo sapiens (human)
Impaired BRCA2 translocation to the nucleus	26S proteasome complex subunit SEM1 Breast cancer type 2 susceptibility protein	P51587 P60896	BRCA2 C7orf76 DSS1 FACD FANCD1 SEM1 SHFDG1 SHFM1	Homo sapiens (human)
Thrombin signalling through proteinase activated receptors (PARs)	Beta-arrestin-1 Beta-arrestin-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-12 Guanine nucleotide-binding protein subunit alpha-13 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Proteinase-activated receptor 1 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin	O00254 O14610 O14775 O60262 O95837 P00734 P16520 P25116 P27361 P28482 P29992 P30679 P32121 P49407 P50148 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q03113 Q14344 Q96RI0 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ARB2 ARR1 ARR2 ARRB1 ARRB2 CF2R ERK1 ERK2 F2 F2R F2RL2 F2RL3 GA11 GAQ GNA11 GNA12 GNA13 GNA14 GNA15 GNA16 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 MAPK1 MAPK3 PAR1 PAR3 PAR4 PRKM1 PRKM2 PRKM3 TR	Homo sapiens (human)
FCGR3A-mediated IL10 synthesis	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Calmodulin-1 High affinity immunoglobulin gamma Fc receptor I IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Interleukin-10 Low affinity immunoglobulin gamma Fc region receptor II-a Low affinity immunoglobulin gamma Fc region receptor III-A Putative GIPL galf transferase S-adenosylhomocysteine hydrolase-like protein 1 T-cell surface glycoprotein CD3 gamma chain Tyrosine-protein kinase Fgr Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O43306 O43865 O60266 O60503 O95622 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07947 P07948 P08631 P08637 P09693 P09769 P0CF74 P0CG04 P0DOY2 P0DOY3 P0DP23 P10644 P12314 P12318 P13861 P16885 P17612 P19174 P22301 P22612 P22694 P23083 P31321 P31323 P40145 P43405 P51817 P51828 P80748 Q08462 Q08828 Q14571 Q14573 Q14643 Q4QD44 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 AHCYL1 CALM CALM1 CAM CAM1 CD16A CD32 CD3G DCAL FCG1 FCG2 FCG3 FCGR1 FCGR1A FCGR2A FCGR2A1 FCGR3 FCGR3A FGR FYN HCK IGFR1 IGFR2 IGFR3 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IL10 INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 JTK8 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 LPG1G LPG1G2 LYN PKACA PKR1 PKR2 PKX1 PLC1 PLCG1 PLCG2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX SRC2 SYK T3G TSE1 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 XPVKONA YES YES1	Homo sapiens (human)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Aurora kinase A Aurora kinase B Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Fizzy-related protein homolog Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Retinoblastoma-associated protein S-phase kinase-associated protein 2 Securin Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O00762 O14818 O14965 O43242 O95997 P06400 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30260 P35998 P43686 P48556 P49720 P49721 P51665 P51668 P51965 P53350 P60006 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q12834 Q13042 Q13200 Q13309 Q15008 Q16186 Q16763 Q8NHZ8 Q96DE5 Q96GD4 Q99436 Q99460 Q9H1A4 Q9NYG5 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM11 Q9UM13 Q9UNM6	ADRM1 AIK AIK2 AIM1 AIRK1 AIRK2 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 ARK1 ARK2 AURA AURKA AURKB AYK1 BTAK C10orf104 C11orf51 C7orf76 C9orf17 CDC16 CDC20 CDC23 CDC26 CDC27 CDH1 CENP-27 D0S1430E D17S978E DSS1 E2EPF EAP1 FBXL1 FYR FZR FZR1 GP110 HC2 HC3 HC8 HC9 HSPC IAK1 KIAA0107 KIAA1242 KIAA1406 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 PLK PLK1 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTTG PTTG1 RB1 RPS27A SEM1 SFT SHFDG1 SHFM1 SKP2 STK1 STK12 STK15 STK5 STK6 SUG1 SUG2 TBP1 TBP7 TRAP2 TSG24 TUTR1 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S X Y Z	Homo sapiens (human)
Masitinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Attachment and Entry	Agrin Angiotensin-converting enzyme 2 Basement membrane-specific heparan sulfate proteoglycan core protein Envelope small membrane protein Furin Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Hepatitis A virus cellular receptor 1 Membrane protein Neuropilin-1 Nucleoprotein ORF3a protein ORF7a protein Procathepsin L Spike glycoprotein Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4 Transitional endoplasmic reticulum ATPase Transmembrane protease serine 2	O00468 O14786 O15393 O75056 O75487 P07711 P09958 P0DTC2 P0DTC3 P0DTC4 P0DTC5 P0DTC7 P0DTC9 P18827 P31431 P34741 P35052 P51654 P55072 P78333 P98160 Q8N158 Q96D42 Q9BYF1 Q9Y625	3a 7a ACE2 AGRIN AGRN CTSL CTSL1 E FUR FURIN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HAVCR1 HEL-220 HEL-S-70 HSPG1 HSPG2 KIAA0468 KIM1 M N NRP NRP1 OCI5 PACE PCSK3 PRSS10 S SDC SDC1 SDC2 SDC3 SDC4 TIM1 TIMD1 TMPRSS2 VCP VEGF165R	Homo sapiens (human)
EPHA-mediated growth cone collapse	Ephexin-1 Myosin light polypeptide 6 Myosin regulatory light chain 12B Myosin regulatory light polypeptide 9 Myosin-10 Myosin-11 Myosin-14 Myosin-9 Rho-associated protein kinase 1 Rho-associated protein kinase 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lyn Tyrosine-protein kinase Yes	O14950 O75116 P06241 P07947 P07948 P24844 P35579 P35580 P35749 P60660 P61586 Q13464 Q7Z406 Q8N5V2	ARH12 ARHA FYN JTK8 KIAA0619 KIAA0866 KIAA2034 LYN MLC2 MRLC1 MRLC2 MYH10 MYH11 MYH14 MYH9 MYL12B MYL6 MYL9 MYLC2B MYRL2 NGEF RHO12 RHOA ROCK1 ROCK2 YES YES1	Homo sapiens (human)
MAP2K and MAPK activation	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Interleukin-17 receptor D Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Vinculin WD repeat domain-containing protein 83 von Willebrand factor	P01111 P01112 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q6VAB6 Q7Z5R6 Q8IVT5 Q8NFM7 Q8WXI2 Q969H4 Q9BRX9 Q9UHA4 Q9Y2Q5 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IL17RD IL17RLM IQGAP1 ITGA2B ITGAB ITGB3 KIAA0051 KIAA0902 KIAA1027 KREV1 KSR KSR1 KSR2 LAMTOR2 LAMTOR3 MAP2K1 MAP2K1IP1 MAP2K2 MAPBPIP MAPK1 MAPK3 MAPKSP1 MARK3 MEK1 MEK2 MKK2 MORG1 NRAS PBP PEBP PEBP1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RIAM ROBLD3 SEF SRC SRC1 TLN TLN1 VCL VWF WDR83 YWHAB	Homo sapiens (human)
Activated NTRK2 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Neurotrophin-4	P19174 P23560 P34130 Q16620	BDNF NTF4 NTF5 NTRK2 PLC1 PLCG1 TRKB	Homo sapiens (human)
KIT mutants bind TKIs	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	182 kDa tankyrase-1-binding protein CCR4-NOT transcription complex subunit 10 CCR4-NOT transcription complex subunit 11 CCR4-NOT transcription complex subunit 1 CCR4-NOT transcription complex subunit 2 CCR4-NOT transcription complex subunit 3 CCR4-NOT transcription complex subunit 4 CCR4-NOT transcription complex subunit 6-like CCR4-NOT transcription complex subunit 6 CCR4-NOT transcription complex subunit 7 CCR4-NOT transcription complex subunit 8 CCR4-NOT transcription complex subunit 9 Cellular tumor antigen p53 Centromere protein J M-phase inducer phosphatase 3 Nucleophosmin Protein BTG2 Regulator of cell cycle RGCC Serine/threonine-protein kinase PLK2 Serine/threonine-protein kinase PLK3 Zinc finger protein PLAGL1	A5YKK6 O75175 O95628 P04637 P06748 P30307 P78543 Q92600 Q96LI5 Q9C0C2 Q9H4B4 Q9H4X1 Q9H9A5 Q9HC77 Q9NYY3 Q9NZN8 Q9UFF9 Q9UIV1 Q9UKZ1 Q9ULM6 Q9UM63	BTG2 C13orf15 C2orf29 CAF1 CALIF CCR4 CCR4B CCR4a CDC25C CDC36 CDC39 CENPJ CNK CNOT1 CNOT10 CNOT11 CNOT2 CNOT3 CNOT4 CNOT6 CNOT6L CNOT7 CNOT8 CNOT9 CPAP FNK KIAA0691 KIAA1007 KIAA1194 KIAA1741 LAP LENG2 LIP1 LOT1 NOT1 NOT2 NOT3 NOT4 NPM NPM1 P53 PC3 PLAGL1 PLK2 PLK3 POP2 PRK RCD1 RGC32 RGCC RQCD1 SNK TAB182 TNKS1BP1 TP53 ZAC	Homo sapiens (human)
Defective MAOA causes BRUNS	Amine oxidase [flavin-containing] A	P21397	MAOA	Homo sapiens (human)
Release	Hemagglutinin Matrix protein 1 Matrix protein 2 Neuraminidase Nuclear export protein Nucleoprotein Polymerase acidic protein Polymerase basic protein 2 RNA-directed RNA polymerase catalytic subunit	P03428 P03431 P03433 P03452 P03466 P03468 P03485 P03508 P06821	HA M NA NP NS PA PB1 PB2	Homo sapiens (human)
The retinoid cycle in cones (daylight vision)	Acyl-CoA wax alcohol acyltransferase 2 Long-wave-sensitive opsin 1 Medium-wave-sensitive opsin 1 Retinaldehyde-binding protein 1 Retinol-binding protein 3 Short-chain dehydrogenase/reductase 3 Short-wave-sensitive opsin 1	O75911 P03999 P04000 P04001 P10745 P12271 Q6E213	AWAT2 BCP CRALBP DC4 DGAT2L4 DHRS3 GCP MFAT OPN1LW OPN1MW OPN1SW RBP3 RCP RDH17 RLBP1 SDR16C1 WS	Homo sapiens (human)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	ATP-sensitive inward rectifier potassium channel 10 ATP-sensitive inward rectifier potassium channel 12 ATP-sensitive inward rectifier potassium channel 15 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 3 G protein-activated inward rectifier potassium channel 4 Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inward rectifier potassium channel 16 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4	O14610 O14775 O60262 O75899 P16520 P48050 P48051 P48544 P48549 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P63252 P78508 Q14500 Q92806 Q99712 Q9HAV0 Q9NPI9 Q9P2W3 Q9UBI6 Q9UBS5 Q9UK08	GABBR1 GABBR2 GIRK1 GIRK2 GIRK3 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPR51 GPRC3A GPRC3B IRK1 IRK2 IRK3 KATP2 KCNJ10 KCNJ12 KCNJ14 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6 KCNJ7 KCNJ9 KCNJN1	Homo sapiens (human)

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