GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **1851 - 1875** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	GlyTouCan ID
Phase I - Functionalization of compounds	Aldehyde dehydrogenase, dimeric NADP-preferring Amine oxidase [copper-containing] 2 Amine oxidase [copper-containing] 3 Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Carbonyl reductase [NADPH] 3 Carboxylesterase 3 Carboxymethylenebutenolidase homolog Cocaine esterase Cytochrome P450 2B6 Cytochrome P450 3A4 Cytochrome b5 type B Diamine oxidase [copper-containing] Epoxide hydrolase 1 Liver carboxylesterase 1 Mitochondrial amidoxime reducing component 2 Mitochondrial amidoxime-reducing component 1 NADH-cytochrome b5 reductase 3 Ribosyldihydronicotinamide dehydrogenase [quinone] Valacyclovir hydrolase	A9YTQ3 O00748 O43169 O75106 O75828 P00387 P07099 P08684 P16083 P19801 P20813 P22760 P23141 P27540 P30838 P35869 Q16853 Q5VT66 Q6UWW8 Q86WA6 Q969Z3 Q96DG6 Q9HBZ2	AADAC ABP ABP1 AHR AHRR ALDH3 ALDH3A1 AOC1 AOC2 AOC3 ARNT ARNT2 BHLHE1 BHLHE2 BHLHE76 BHLHE77 BPHL CBR3 CES1 CES2 CES3 CMBL CYB5B CYB5M CYB5R3 CYP2B6 CYP3A3 CYP3A4 DAC DAO DIA1 EPHX EPHX1 EPOX ICE KIAA0307 KIAA1234 MARC1 MARC2 MCNAA MOSC1 MOSC2 MTARC1 MTARC2 NMOR2 NQO2 OMB5 SDR21C2 SES1 VAP1
Aryl hydrocarbon receptor signalling	AH receptor-interacting protein Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Heat shock protein HSP 90-beta Prostaglandin E synthase 3	A9YTQ3 O00170 P08238 P27540 P35869 Q15185 Q9HBZ2	AHR AHRR AIP ARNT ARNT2 BHLHE1 BHLHE2 BHLHE76 BHLHE77 HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KIAA0307 KIAA1234 P23 PTGES3 TEBP XAP2
Regulation of localization of FOXO transcription factors	14-3-3 protein beta/alpha 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase	A8MYZ6 O43524 P27348 P31749 P31751 P31946 P31947 P61981 P63104 P98177 Q12778 Q9Y243	AFX AFX1 AKT1 AKT2 AKT3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 HME1 MLLT7 PKB PKBG RAC SFN YWHAB YWHAG YWHAQ YWHAZ
AKT phosphorylates targets in the nucleus	Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Nuclear receptor subfamily 4immunitygroup A member 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ribosomal protein S6 kinase beta-2	A8MYZ6 O43524 P22736 P31749 P31751 P98177 Q12778 Q9UBS0 Q9Y243	AFX AFX1 AKT1 AKT2 AKT3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 GFRP1 HMR MLLT7 NAK1 NR4A1 PKB PKBG RAC RPS6KB2 STK14B
Constitutive Signaling by AKT1 E17K in Cancer	3-phosphoinositide-dependent protein kinase 1 Bcl2-associated agonist of cell death Caspase-9 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B E3 ubiquitin-protein ligase Mdm2 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Inhibitor of nuclear factor kappa-B kinase subunit alpha Nuclear receptor subfamily 4immunitygroup A member 1 Proline-rich AKT1 substrate 1 Proline-rich protein 5 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Rapamycin-insensitive companion of mTOR Ribosomal protein S6 kinase beta-2 Serine/threonine-protein kinase mTOR Target of rapamycin complex 2 subunit MAPKAP1 Target of rapamycin complex subunit LST8 Tuberin	A8MYZ6 O15111 O15530 O43524 P22736 P31749 P31751 P38936 P42345 P46527 P49815 P49840 P49841 P55211 P85299 P98177 Q00987 Q12778 Q6R327 Q92934 Q96B36 Q9BPZ7 Q9BVC4 Q9UBS0 Q9Y243	AFX AFX1 AKT1 AKT1S1 AKT2 AKT3 BAD BBC6 BCL2L8 CAP20 CASP9 CDKN1 CDKN1A CDKN1B CHUK CIP1 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 FRAP FRAP1 FRAP2 GBL GFRP1 GSK3A GSK3B HMR IKKA KIAA1999 KIP1 LST8 MAPKAP1 MCH6 MDA6 MDM2 MIP1 MLLT7 MLST8 MTOR NAK1 NR4A1 PDK1 PDPK1 PIC1 PKB PKBG PRAS40 PROTOR1 PRR5 RAC RAFT1 RAPT1 RICTOR RPS6KB2 SDI1 SIN1 STK14B TCF16 TSC2 TSC4 WAF1 p27
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	ATP-binding cassette sub-family A member 6 Agouti-related protein Ataxin-3 Catalase E3 ubiquitin-protein ligase TRIM63 F-box only protein 32 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Glucocorticoid receptor Glucose-6-phosphatase catalytic subunit 1 Hexokinase-4 Histone deacetylase 1 Histone deacetylase 2 Insulin-like growth factor-binding protein 1 Insulin Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 NAD-dependent protein deacetylase sirtuin-3, mitochondrial Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Plexin-A4 Pro-neuropeptide Y Pro-opiomelanocortin Resistin Sterol regulatory element-binding protein 1 Superoxide dismutase [Mn], mitochondrial	A8MYZ6 O00253 O43524 P01189 P01303 P01308 P04040 P04150 P04179 P08833 P35557 P35558 P35575 P36956 P54252 P84022 P98177 Q12778 Q13485 Q13547 Q15796 Q8N139 Q92769 Q969P5 Q969Q1 Q96ST3 Q9HCM2 Q9HD89 Q9NTG7 Q9UBK2	ABCA6 AFX AFX1 AGRP AGRT ART ATX3 ATXN3 BHLHD1 CAT DPC4 FBXO32 FIZZ3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 G6PC G6PC1 G6PT GCK GRL HDAC1 HDAC2 HXCP1 IBP1 IGFBP1 INS IRF KIAA1550 LEM6 MADH2 MADH3 MADH4 MADR2 MJD MJD1 MLLT7 MURF1 NPY NR3C1 PCK1 PEPCK1 PGC1 PGC1A PLXNA4 PLXNA4A PLXNA4B POMC PPARGC1 PPARGC1A RETN RNF28 RPD3L1 RSTN SCA3 SIN3A SIR2L3 SIRT3 SMAD2 SMAD3 SMAD4 SMRZ SOD2 SREBF1 SREBP1 TRIM63
Sperm Motility And Taxes	Cation channel sperm-associated auxiliary subunit beta Cation channel sperm-associated auxiliary subunit delta Cation channel sperm-associated auxiliary subunit gamma Cation channel sperm-associated protein 1 Cation channel sperm-associated protein 2 Cation channel sperm-associated protein 3 Cation channel sperm-associated protein 4 Potassium channel subfamily U member 1 Voltage-gated hydrogen channel 1	A8MYU2 Q6ZRH7 Q7RTX7 Q86XM0 Q86XQ3 Q8NEC5 Q96D96 Q96P56 Q9H7T0	C14orf161 C19orf15 CATSPER1 CATSPER2 CATSPER3 CATSPER4 CATSPERB CATSPERD CATSPERG HVCN1 KCNMA3 KCNMC1 KCNU1 SLO3 TMEM146 VSOP
Peroxisomal lipid metabolism	2-Hydroxyacid oxidase 2 Acyl-CoA-binding domain-containing protein 4 Acyl-CoA-binding domain-containing protein 5 Acyl-coenzyme A diphosphatase NUDT19 Peroxisomal coenzyme A diphosphatase NUDT7	A8MXV4 P0C024 Q5T8D3 Q8NC06 Q9NYQ3	ACBD4 ACBD5 HAO2 HAOX2 KIAA1996 NUDT19 NUDT7
Peroxisomal protein import	2-Hydroxyacid oxidase 1 2-Hydroxyacid oxidase 2 2-hydroxyacyl-CoA lyase 1 3-ketoacyl-CoA thiolase, peroxisomal AN1-type zinc finger protein 6 Acyl-coenzyme A diphosphatase NUDT19 Acyl-coenzyme A thioesterase 2, mitochondrial Acyl-coenzyme A thioesterase 8 Alanine--glyoxylate aminotransferase Alkyldihydroxyacetonephosphate synthase, peroxisomal Alpha-methylacyl-CoA racemase Bifunctional epoxide hydrolase 2 Bile acid-CoA Carnitine O-acetyltransferase Catalase D-amino-acid oxidase D-aspartate oxidase Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Glutathione S-transferase kappa 1 Hydroxymethylglutaryl-CoA lyase, mitochondrial Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] cytoplasmic Lon protease homolog 2, peroxisomal Long-chain fatty acid transport protein 2 Nitric oxide synthase, inducible Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] Peroxisomal ATPase PEX1 Peroxisomal ATPase PEX6 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase Peroxisomal acyl-coenzyme A oxidase 1 Peroxisomal acyl-coenzyme A oxidase 2 Peroxisomal acyl-coenzyme A oxidase 3 Peroxisomal bifunctional enzyme Peroxisomal carnitine O-octanoyltransferase Peroxisomal coenzyme A diphosphatase NUDT7 Peroxisomal leader peptide-processing protease Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal multifunctional enzyme type 2 Peroxisomal sarcosine oxidase Peroxisomal succinyl-coenzyme A thioesterase Peroxisomal targeting signal 2 receptor Peroxisomal trans-2-enoyl-CoA reductase Peroxisome assembly protein 12 Peroxisome assembly protein 26 Peroxisome biogenesis factor 10 Peroxisome biogenesis factor 2 Phytanoyl-CoA dioxygenase, peroxisomal Polyubiquitin-B Polyubiquitin-C Protein Mpv17 Sterol carrier protein 2 Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-conjugating enzyme E2 D3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MXV4 O00116 O00623 O00628 O14734 O14832 O14975 O15228 O15254 O43933 O60683 O75381 O75874 P04040 P09110 P0C024 P0CG47 P0CG48 P14735 P14920 P21549 P22307 P28328 P34913 P35228 P35914 P39210 P43155 P49753 P51659 P51668 P61077 P62837 P62979 P62987 Q08426 Q13011 Q13608 Q14032 Q15067 Q2T9J0 Q6FIF0 Q6QHF9 Q7Z412 Q86WA8 Q8N9L9 Q92968 Q93008 Q99424 Q99489 Q9BTZ2 Q9BY49 Q9NUI1 Q9NYQ3 Q9P0Z9 Q9UHK6 Q9UJ83 Q9UJM8 Q9UKG9 Q9Y2Q3	ACAA ACAA1 ACOT2 ACOT4 ACOT8 ACOX ACOX1 ACOX2 ACOX3 ACSVL1 ACTEIII AGPS AGT1 AGXT AMACR AWP1 BAAT BRCOX CAT CAT1 COT CRAT CROT DAMOX DAO DAPAT DDO DECR2 DFFRX DHAPAT DHRS4 ECH1 ECHD EDH17B4 EHHADH EPHX2 FACVL1 FAM FATP2 GNPAT GOX1 GSTK1 HACL1 HAO1 HAO2 HAOX2 HMGCL HPCL HPCL2 HSD17B4 IDE IDH1 LONP LONP2 LPIPOX MPV17 NOS2 NOS2A NUDT19 NUDT7 PAF1 PAF3 PAHX PAO PAOX PDCR PECR PEX1 PEX10 PEX12 PEX13 PEX14 PEX2 PEX26 PEX6 PEX7 PHYH PHYH2 PICD PIPOX PMP3 PMP35 PRCOX PSO PTE1 PTE2 PTE2A PTE2B PTEIB PTHIO PTS2R PUBC1 PXAAA1 PXMP3 RNF69 RNF72 RPS27A SCP2 SDR17C1 SDR25C2 SDR29C1 SDR8C1 SFT SLC27A2 SPAT TYSND1 UBA52 UBA80 UBB UBC UBC4 UBC5A UBC5B UBC5C UBCEP1 UBCEP2 UBCH4 UBCH5 UBCH5A UBCH5B UBCH5C UBE2D1 UBE2D2 UBE2D3 USP9 USP9X VLACS ZA20D3 ZFAND6
Beta defensins	Beta-defensin (Fragment) Beta-defensin 103 Beta-defensin 104 Beta-defensin 105 Beta-defensin 106 Beta-defensin 107 Beta-defensin 108B Beta-defensin 110 Beta-defensin 112 Beta-defensin 113 Beta-defensin 114 Beta-defensin 115 Beta-defensin 116 Beta-defensin 119 Beta-defensin 121 Beta-defensin 123 Beta-defensin 124 Beta-defensin 125 Beta-defensin 126 Beta-defensin 127 Beta-defensin 128 Beta-defensin 129 Beta-defensin 130A Beta-defensin 130B Beta-defensin 131A Beta-defensin 132 Beta-defensin 133 Beta-defensin 134 Beta-defensin 135 Beta-defensin 1 C-C chemokine receptor type 2 C-C chemokine receptor type 6 Defensin beta 118 Defensin beta 136 Defensin beta 4A Putative beta-defensin 108A Putative beta-defensin 109B Toll-like receptor 1 Toll-like receptor 2	A8MXU0 O15263 O60603 P0DP73 P0DP74 P41597 P51684 P59861 P60022 P81534 Q15399 Q30KP8 Q30KP9 Q30KQ1 Q30KQ3 Q30KQ4 Q30KQ5 Q30KQ6 Q30KQ7 Q30KQ8 Q30KQ9 Q30KR1 Q4QY38 Q5J5C9 Q7Z7B7 Q7Z7B8 Q8IZN7 Q8N104 Q8N687 Q8N688 Q8N690 Q8NES8 Q8NET1 Q8NG35 Q8WTQ1 Q96PH6 Q9BYW3 Q9H1M3 Q9H1M4	BD1 BD3 BD5 BD6 C20orf63 C20orf73 C20orf8 C20orf87 CCR2 CCR6 CKRL3 CMKBR2 CMKBR6 DEFB1 DEFB10 DEFB102 DEFB103 DEFB103A DEFB103B DEFB104 DEFB104A DEFB104B DEFB105 DEFB105A DEFB105B DEFB106 DEFB106A DEFB106B DEFB107 DEFB107A DEFB107B DEFB108 DEFB108A DEFB108B DEFB108C DEFB108P1 DEFB108P2 DEFB109B DEFB109P1B DEFB11 DEFB110 DEFB111 DEFB112 DEFB113 DEFB114 DEFB115 DEFB116 DEFB117 DEFB118 DEFB119 DEFB12 DEFB120 DEFB121 DEFB123 DEFB124 DEFB125 DEFB126 DEFB127 DEFB128 DEFB129 DEFB13 DEFB130 DEFB130A DEFB130B DEFB131 DEFB131A DEFB132 DEFB133 DEFB134 DEFB135 DEFB136 DEFB14 DEFB15 DEFB16 DEFB18 DEFB19 DEFB2 DEFB20 DEFB21 DEFB23 DEFB24 DEFB25 DEFB26 DEFB27 DEFB28 DEFB29 DEFB3 DEFB30 DEFB31 DEFB32 DEFB4 DEFB4A DEFB4B DEFB5 DEFB6 DEFB7 DEFB8 ESC42 GPR29 HBD1 KIAA0012 STRL22 TIL4 TLR1 TLR2
Formation of WDR5-containing histone-modifying complexes	A-kinase anchor protein 8-like Biorientation of chromosomes in cell division protein 1-like 1 Biorientation of chromosomes in cell division protein 1 CXXC-type zinc finger protein 1 Cysteine-rich protein 2-binding protein Histone acetyltransferase KAT2A Histone acetyltransferase KAT2B Histone acetyltransferase KAT8 Histone-lysine N-methyltransferase 2A Histone-lysine N-methyltransferase 2B Histone-lysine N-methyltransferase 2C Histone-lysine N-methyltransferase 2D Histone-lysine N-methyltransferase SETD1A Histone-lysine N-methyltransferase SETD1B Host cell factor 1 Host cell factor 2 KAT8 regulatory NSL complex subunit 1 KAT8 regulatory NSL complex subunit 2 KAT8 regulatory NSL complex subunit 3 Lysine-specific demethylase 6A MAP3K12-binding inhibitory protein 1 Menin Microspherule protein 1 Nuclear receptor coactivator 6 PAX-interacting protein 1 PAXIP1-associated glutamate-rich protein 1 PC4 and SFRS1-interacting protein PHD finger protein 20-like protein 1 PHD finger protein 20 Protein Dr1 Protein dpy-30 homolog Retinoblastoma-binding protein 5 SAGA-associated factor 29 Set1/Ash2 histone methyltransferase complex subunit ASH2 Threonine aspartase 1 Transcriptional adapter 2-alpha Transcriptional adapter 3 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit WD repeat-containing protein 5 WD repeat-containing protein 82 YEATS domain-containing protein 2 ZZ-type zinc finger-containing protein 3	A8MW92 O00255 O14686 O15047 O15294 O15550 O75475 O75478 O75528 P51610 P61964 Q01658 Q03164 Q14686 Q15291 Q6UXN9 Q6ZW49 Q7Z3B3 Q8IYH5 Q8NEZ4 Q8NFC6 Q92830 Q92831 Q96ES7 Q96EZ8 Q96IK1 Q9BTK6 Q9BVI0 Q9C005 Q9H6P5 Q9H7Z6 Q9H8E8 Q9H9L4 Q9NS73 Q9P0U4 Q9P2N6 Q9UBL3 Q9ULM3 Q9ULX6 Q9UMN6 Q9UPS6 Q9Y5Z7	ADA3 AIB3 AKAP8L ALL1 ALR ASH2L ASH2L1 BIG3 BOD1 BOD1L BOD1L1 C12orf41 C16orf53 C20orf104 C20orf13 CCDC101 CENP-36 CFP1 CGBP CSRP2BP CXXC1 CXXC7 DFS70 DPY30 DR1 FAM44A FAM44B GCN5 GCN5L2 GLEA2 HALR HCA58 HCF1 HCFC1 HCFC2 HFC1 HRX HRX2 HTRX INO80Q KANSL1 KANSL2 KANSL3 KAT14 KAT2A KAT2B KAT8 KDM6A KIAA0181 KIAA0304 KIAA0339 KIAA1076 KIAA1197 KIAA1267 KIAA1310 KIAA1327 KIAA1506 KMT2A KMT2B KMT2C KMT2D KMT2F KMT2G LEDGF MBIP MCRS1 MEN1 MLL MLL1 MLL2 MLL3 MLL4 MOF MSL1V1 MSP58 MYST1 NAKAP NAKAP95 NCOA6 NSL1 NSL2 NSL3 NZF OGT PA1 PAGR1 PAXIP1 PAXIP1L PCAF PCCX1 PHF18 PHF20 PHF20L1 PRTD PSIP1 PSIP2 PTIP RAP250 RBBP5 RBQ3 SCG2 SET1 SET1A SET1B SETD1A SETD1B SGF29 SI1 SWD2 TADA2A TADA2L TADA3 TADA3L TASP1 TMEM113 TRBP TRX1 TRX2 TZP UTX WBP7 WDR5 WDR82 WDR82A YEATS2 ZZZ3
BBSome-mediated cargo-targeting to cilium	ADP-ribosylation factor-like protein 6 BBSome-interacting protein 1 Bardet-Biedl syndrome 1 protein Bardet-Biedl syndrome 10 protein Bardet-Biedl syndrome 12 protein Bardet-Biedl syndrome 2 protein Bardet-Biedl syndrome 4 protein Bardet-Biedl syndrome 5 protein Bardet-Biedl syndrome 7 protein Leucine zipper transcription factor-like protein 1 Melanin-concentrating hormone receptor 1 Molecular chaperone MKKS Protein PTHB1 Protein smoothened Rab-3A-interacting protein Somatostatin receptor type 3 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit gamma T-complex protein 1 subunit theta Tetratricopeptide repeat protein 8	A8MTZ0 P17987 P32745 P48643 P49368 P50990 P50991 P78371 Q3SYG4 Q6ZW61 Q8IWZ6 Q8N3I7 Q8NFJ9 Q8TAM1 Q8TAM2 Q96QF0 Q96RK4 Q99705 Q99835 Q9BXC9 Q9H0F7 Q9NPJ1 Q9NQ48	99D8.1 ARL6 BBIP1 BBIP10 BBS1 BBS10 BBS12 BBS2 BBS2L1 BBS2L2 BBS3 BBS4 BBS5 BBS6 BBS7 BBS8 BBS9 C12orf58 C21orf112 C4orf24 CCT1 CCT2 CCT3 CCT4 CCT5 CCT8 CCTA CCTB CCTD CCTE CCTG CCTQ GPR24 KIAA0002 KIAA0098 LZTFL1 MCHR1 MKKS NCRNA00081 PTHB1 RAB3IP RABIN8 SLC1 SMO SMOH SRB SSTR3 TCP1 TRIC5 TTC8
Formation of axial mesoderm	Catenin beta-1 Forkhead box protein H1 Hepatocyte nuclear factor 3-alpha Hepatocyte nuclear factor 3-beta Homeobox protein notochord Lymphoid enhancer-binding factor 1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Sonic hedgehog protein T-box transcription factor T Transcription factor 7 Transcriptional coactivator YAP1 Transcriptional enhancer factor TEF-3 Transcriptional enhancer factor TEF-4	A8MTQ0 O15178 O75593 P35222 P36402 P46937 P55317 P84022 Q15465 Q15561 Q15562 Q15796 Q9UJU2 Q9Y261	CTNNB CTNNB1 FAST1 FAST2 FOXA1 FOXA2 FOXH1 HNF3A HNF3B LEF1 MADH2 MADH3 MADR2 NOTO RTEF1 SHH SMAD2 SMAD3 T TBXT TCF1 TCF13L1 TCF3A TCF3B TCF7 TEAD2 TEAD4 TEF3 TEF4 YAP1 YAP65
Sensory perception of sweet, bitter, and umami (glutamate) taste	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 Calcium homeostasis modulator protein 1 Calcium homeostasis modulator protein 3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Inositol 1,4,5-trisphosphate receptor type 3 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 4 Sodium channel protein type 2 subunit alpha Sodium channel protein type 3 subunit alpha Sodium channel protein type 9 subunit alpha Sodium channel subunit beta-1 Sodium channel subunit beta-2 Sodium channel subunit beta-4 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 43 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Transient receptor potential cation channel subfamily M member 4 Transient receptor potential cation channel subfamily M member 5	A8MTJ3 O60939 P16520 P59533 P59534 P59535 P59536 P59537 P59538 P59540 P59541 P59543 P59544 P62873 Q00722 Q07699 Q13255 Q14573 Q14833 Q15858 Q7RTX0 Q7RTX1 Q86XJ0 Q8IU99 Q8IWT1 Q8TD43 Q8TE23 Q99250 Q9NY46 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9NZQ8 Q9P2W3	CALHM1 CALHM3 FAM26A FAM26C GNAT3 GNB1 GNB3 GNG13 GPR60 GPR70 GPR71 GPRC1A GPRC1D GRM1 GRM4 HBA ITPR3 KIAA1356 LTRPC4 LTRPC5 MGLUR1 MGLUR4 MTR1 NAC2 NAC3 NENA PLCB2 PTC SCN1B SCN2A SCN2A1 SCN2A2 SCN2B SCN3A SCN4B SCN9A T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R20 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R43 TAS2R44 TAS2R46 TAS2R47 TAS2R49 TAS2R5 TAS2R50 TAS2R7 TAS2R8 TR1 TR2 TR3 TRPM4 TRPM5	G58161NS
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3	A8MTJ3 O43306 O60266 O60503 O95622 P04899 P08754 P38405 P40145 P51828 P63096 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAI1 GNAI2 GNAI2B GNAI3 GNAL GNAT3 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Catenin beta-1 Dipeptidyl peptidase 4 Free fatty acid receptor 1 Free fatty acid receptor 4 Gastrin-releasing peptide Glucose-dependent insulinotropic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Homeobox protein CDX-2 Leptin Neuroendocrine convertase 1 Paired box protein Pax-6 Pro-glucagon Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex catalytic subunit SEC11C Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Transcription factor 7-like 2	A8MTJ3 O14842 P01275 P07492 P16520 P26367 P27487 P29120 P35222 P41159 P61009 P62873 P67812 Q15005 Q5NUL3 Q8TDV5 Q99626 Q9BY50 Q9NQB0 Q9P2W3 Q9Y6A9	ADCP2 AN2 CD26 CDX2 CDX3 CTNNB CTNNB1 DPP4 FFAR1 FFAR4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GPR120 GPR129 GPR40 GRP KIAA0102 LEP NEC1 O3FAR1 OB OBS PAX6 PCSK1 PGR4 SEC11A SEC11C SEC11L1 SEC11L3 SPC12 SPC18 SPC21 SPC22 SPC25 SPCS1 SPCS2 SPCS3 SPCS4A SPCS4C TCF4 TCF7L2	G58161NS
ADP signalling through P2Y purinoceptor 12	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 P2Y purinoceptor 12	A8MTJ3 O14610 O14775 O60262 P04899 P08754 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63096 P63211 P63215 P63218 Q9H244 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	GNAI1 GNAI2 GNAI2B GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 HORK3 P2RY12
GPER1 signaling	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 G-protein coupled estrogen receptor 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Integrin alpha-5 Integrin beta-1 Proto-oncogene tyrosine-protein kinase Src cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A8MTJ3 O14610 O14775 O43306 O60262 O60266 O60503 O95622 P04899 P05556 P08648 P08754 P10644 P12931 P13861 P16520 P17612 P19086 P22612 P22694 P31321 P31323 P40145 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q99527 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 CEPR CMKRL2 DRY12 FNRA FNRB GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPER GPER1 GPR30 GSP ITGA5 ITGB1 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 MDF2 MSK12 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B SRC SRC1 TSE1
ADORA2B mediated anti-inflammatory cytokines production	Adenosine receptor A2b Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Interleukin-6 cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A8MTJ3 O14610 O14775 O43306 O60262 O60266 O60503 O95622 P04899 P05231 P08754 P10644 P13861 P16520 P17612 P19086 P22612 P22694 P29275 P31321 P31323 P40145 P50150 P50151 P51817 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADORA2B GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP IFNB2 IL6 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKACA PKR1 PKR2 PKX1 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX TSE1
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Amphiregulin Calmodulin-1 Caveolin-1 Caveolin-2 Epidermal growth factor receptor Epigen Estrogen receptor beta Estrogen receptor Focal adhesion kinase 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Heat shock protein HSP 90-alpha Insulin-like growth factor 1 receptor Matrilysin Matrix metalloproteinase-9 Nitric oxide synthase 3 Palmitoyltransferase ZDHHC21 Palmitoyltransferase ZDHHC7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein arginine N-methyltransferase 1 Proto-oncogene tyrosine-protein kinase Src Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase Sphingosine 1-phosphate receptor 3 Sphingosine kinase 1 Striatin Stromelysin-1	A8MTJ3 O00459 O14610 O14775 O14944 O43815 O60262 P00533 P01133 P01135 P03372 P04899 P07900 P08069 P08253 P08254 P08754 P09237 P0DP23 P12931 P14780 P15514 P16520 P27986 P29474 P31749 P35070 P42336 P50150 P50151 P51636 P59768 P61952 P62873 P62879 P63096 P63211 P63215 P63218 Q03135 Q05397 Q6UW88 Q8IVQ6 Q92569 Q92731 Q99075 Q99500 Q99873 Q9HAV0 Q9NXF8 Q9NYA1 Q9P2W3 Q9UBI6 Q9UK08	AKT1 AREG AREGB BTC C9orf108 C9orf47 CALM CALM1 CAM CAM1 CAV CAV1 CAV2 CLG4A CLG4B DTR DTS EDG3 EGF EGFR EPGN ERBB ERBB1 EREG ESR ESR1 ESR2 ESTRB FAK FAK1 GNAI1 GNAI2 GNAI2B GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GRB1 HBEGF HEGFL HER1 HMT2 HRMT1L2 HSP90A HSP90AA1 HSPC1 HSPCA IGF1R IR1B4 MMP2 MMP3 MMP7 MMP9 MPSL1 NOS3 NR3A1 NR3A2 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKB PRMT1 PTK2 PUMP1 RAC S1PR3 SDGF SK1 SPHK SPHK1 SPK SRC SRC1 STMY1 STRN TGFA ZDHHC21 ZDHHC7
G alpha (s) signalling events	3',5'-cyclic-AMP phosphodiesterase 4A 3',5'-cyclic-AMP phosphodiesterase 4C 3',5'-cyclic-AMP phosphodiesterase 4D 3',5'-cyclic-AMP phosphodiesterase 7B 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 6 5-hydroxytryptamine receptor 7 Adenosine receptor A2a Adenosine receptor A2b Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Adrenocorticotropic hormone receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor Beta-adrenergic receptor kinase 1 Beta-arrestin-1 Beta-arrestin-2 Calcitonin gene-related peptide 1 Calcitonin gene-related peptide 2 Calcitonin gene-related peptide type 1 receptor Calcitonin receptor Calcitonin Corticoliberin Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor receptor 2 Cysteinyl leukotriene receptor 2 D(1A) dopamine receptor D(1B) dopamine receptor Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Follicle-stimulating hormone receptor Follitropin subunit beta G protein-coupled receptor kinase 3 G protein-coupled receptor kinase 5 G protein-coupled receptor kinase 6 G-protein coupled bile acid receptor 1 G-protein coupled receptor 15 G-protein coupled receptor 176 G-protein coupled receptor 20 G-protein coupled receptor 39 G-protein coupled receptor 83 G-protein coupled receptor 84 Gastric inhibitory polypeptide receptor Gastric inhibitory polypeptide Glucagon receptor Glucagon-like peptide 1 receptor Glucagon-like peptide 2 receptor Glycoprotein hormone alpha-2 Glycoprotein hormone beta-5 Glycoprotein hormones alpha chain Growth hormone-releasing hormone receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 High affinity 3',5'-cyclic-AMP phosphodiesterase 7A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B Histamine H2 receptor Insulin-like 3 Islet amyloid polypeptide Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Neuropeptide S receptor Neuropeptide S P2Y purinoceptor 11 Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Pituitary adenylate cyclase-activating polypeptide type I receptor Pituitary adenylate cyclase-activating polypeptide Pro-adrenomedullin Pro-glucagon Pro-opiomelanocortin Probable G-protein coupled receptor 150 Probable G-protein coupled receptor 25 Probable G-protein coupled receptor 27 Probable G-protein coupled receptor 32 Probable G-protein coupled receptor 45 Prorelaxin H2 Prostacyclin receptor Prostaglandin D2 receptor Prostaglandin E2 receptor EP2 subtype Prostaglandin E2 receptor EP4 subtype Protein ADM2 Proto-oncogene tyrosine-protein kinase Src Putative trace amine-associated receptor 3 Receptor activity-modifying protein 1 Receptor activity-modifying protein 2 Receptor activity-modifying protein 3 Relaxin receptor 1 Relaxin receptor 2 Relaxin-3 Secretin receptor Secretin Somatoliberin Thyrotropin receptor Thyrotropin subunit beta Trace amine-associated receptor 1 Trace amine-associated receptor 2 Trace amine-associated receptor 5 Trace amine-associated receptor 6 Trace amine-associated receptor 8 Trace amine-associated receptor 9 Tuberoinfundibular peptide of 39 residues VIP peptides Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal polypeptide receptor 2 Vasopressin V2 receptor Vasopressin-neurophysin 2-copeptin cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B	A8MTJ3 O00155 O00408 O14610 O14775 O14804 O43194 O43306 O60262 O60266 O60503 O60658 O60894 O60895 O60896 O75388 O95263 O95622 O95838 P01185 P01189 P01215 P01222 P01225 P01229 P01258 P01270 P01275 P01282 P01286 P04090 P04899 P06850 P06881 P07550 P08588 P08754 P09681 P09683 P0C0P6 P10092 P10997 P12272 P12931 P13945 P16473 P16520 P18509 P19086 P21728 P21918 P22888 P23945 P25021 P25098 P27815 P29274 P29275 P30518 P30988 P32121 P32241 P32245 P33032 P34947 P34969 P34998 P35318 P35408 P35626 P40145 P41586 P41587 P41968 P43116 P43119 P43220 P43250 P47871 P47872 P48546 P49190 P49407 P49685 P50150 P50151 P50406 P51460 P51828 P54750 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q01064 Q01718 Q01726 Q02643 Q03431 Q08462 Q08493 Q08499 Q08828 Q13258 Q13324 Q13370 Q13639 Q13946 Q14432 Q14439 Q16602 Q5JWF2 Q6W5P4 Q7Z4H4 Q86YW7 Q8NFM4 Q8NGU9 Q8TDU6 Q8WXD0 Q8WXF3 Q969N4 Q96A98 Q96G91 Q96RI8 Q96RI9 Q96RJ0 Q96T91 Q99678 Q9HAV0 Q9HBX9 Q9HCR9 Q9NP56 Q9NQS5 Q9NS67 Q9NS75 Q9NYM4 Q9P1P4 Q9P1P5 Q9P2W3 Q9UBI6 Q9UK08 Q9Y233 Q9Y5Y3	ACTHR ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADCYAP1 ADCYAP1R1 ADHR ADM ADM2 ADORA2 ADORA2A ADORA2B ADRB1 ADRB1R ADRB2 ADRB2R ADRB3 ADRB3R ADRBK1 ADRBK2 AM AM2 ARB2 ARR1 ARR2 ARRB1 ARRB2 ARVP AVP AVPR2 B1AR B2AR B3AR BARK BARK1 BARK2 CALC1 CALC2 CALCA CALCB CALCR CALCRL CGA CGRPR CRF2R CRFR CRFR1 CRH CRH2R CRHR CRHR1 CRHR2 CYSLT2 CYSLT2R CYSLTR2 DIR DIR3 DPDE1 DPDE2 DPDE3 DRD1 DRD1B DRD1L2 DRD5 EX33 FSHB FSHR GCG GCGR GHRF GHRH GHRHR GIP GIPR GLP1R GLP2R GNAI1 GNAI2 GNAI2B GNAI3 GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GPA2 GPB5 GPBAR1 GPHA2 GPHB5 GPR102 GPR106 GPR15 GPR150 GPR154 GPR176 GPR20 GPR25 GPR27 GPR32 GPR39 GPR45 GPR57 GPR58 GPR72 GPR83 GPR84 GPRA GPRK5 GPRK6 GREAT GRK2 GRK3 GRK5 GRK6 GSP HRH2 HTR4 HTR6 HTR7 IAPP INSL3 INSL7 JP05 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 KIAA1540 LCGR LGR1 LGR2 LGR3 LGR7 LGR8 LHB LHCGR LHRHR MC1R MC2R MC3R MC4R MC5R MSHR NPS NPSR1 P2RY11 PDE10A PDE11A PDE1A PDE1B PDE2A PDE3A PDE3B PDE4A PDE4C PDE4D PDE7A PDE7B PDE8A PDE8B PDES1B PGR14 PNR POMC PRIPR PTGDR PTGER2 PTGER4 PTGIR PTH PTH1R PTH2 PTH2R PTHLH PTHR PTHR1 PTHR2 PTHRP RAMP1 RAMP2 RAMP3 RLF RLN2 RLN3 RLNL RXFP1 RXFP2 RXN3 SCT SCTR SRC SRC1 SREB1 TA1 TA3 TA4 TA5 TAAR1 TAAR2 TAAR3 TAAR3P TAAR5 TAAR6 TAAR8 TAAR9 TAR1 TAR3 TAR4 TAR5 TGR5 TIP39 TIPF39 TRAR1 TRAR3 TRAR4 TRAR5 TSHB TSHR V2R VIP VIP2R VIPR1 VIPR2 VP ZINS4 ZLUT1 ZSIG51
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein C Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere protein W Centromere protein X Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3-like centromeric protein A Histone H4 Histone-binding protein RBBP4 Histone-binding protein RBBP7 Holliday junction recognition protein Kinetochore scaffold 1 Mis18-binding protein 1 Nucleophosmin Protein Mis18-alpha Protein Mis18-beta Remodeling and spacing factor 1 RuvB-like 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5	A8MT69 O43482 O60264 O60814 P04908 P06748 P06899 P0C5Y9 P16104 P20671 P23527 P33778 P49450 P57053 P58876 P62805 P62807 Q03188 Q09028 Q13352 Q16576 Q16777 Q16778 Q5EE01 Q6FI13 Q6IPU0 Q6P0N0 Q71F23 Q71UI9 Q7L2Z9 Q8N0S6 Q8N257 Q8N2Z9 Q8NCD3 Q8NG31 Q92674 Q93077 Q93079 Q96A08 Q96BT3 Q96H22 Q96T23 Q99877 Q99878 Q99879 Q99880 Q9BS16 Q9BTM1 Q9BU64 Q9H3R5 Q9NSP4 Q9NYP9 Q9Y265	APITD1 C14orf106 C16orf56 C16orf60 C1orf155 C21orf45 C21orf46 C22orf18 C6orf139 C6orf173 CASC5 CENPA CENPC CENPC1 CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CENPW CENPX CUG2 FAAP10 FAAP16 FAKTS FASP1 FLEG1 FSHPRH1 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HBXAP HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HJURP ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INO80H ITGB3BP KIAA1570 KIAA1903 KLIP1 KNL1 KNL2 LRPR1 M18BP1 MCM21R MHF1 MHF2 MIS18A MIS18B MIS18BP1 MLF1IP NMP238 NPM NPM1 NRIF3 OIP5 PANE1 PBIP1 RBAP46 RBAP48 RBBP4 RBBP7 RSF1 RUVBL1 SMARCA5 SNF2H STRA13 TIP49 TIP49A TSH2B URLC9 WCRF135 XAP8
PKR-mediated signaling	ATP-dependent RNA helicase A Alpha-synuclein Cellular tumor antigen p53 Centromere protein S Centromere protein X Cyclin-dependent kinase 1 DnaJ homolog subfamily C member 3 Double-stranded RNA-specific adenosine deaminase Dual specificity mitogen-activated protein kinase kinase 6 E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase ARIH1 E3 ubiquitin-protein ligase FANCL E3 ubiquitin/ISG15 ligase TRIM25 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Fanconi anemia core complex-associated protein 100 Fanconi anemia core complex-associated protein 20 Fanconi anemia core complex-associated protein 24 Fanconi anemia group A protein Fanconi anemia group B protein Fanconi anemia group C protein Fanconi anemia group E protein Fanconi anemia group F protein Fanconi anemia group G protein Fanconi anemia group M protein Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1A Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock-related 70 kDa protein 2 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Interferon-induced, double-stranded RNA-activated protein kinase Interferon-inducible double-stranded RNA-dependent protein kinase activator A Interleukin enhancer-binding factor 2 Interleukin enhancer-binding factor 3 Mitochondrial antiviral-signaling protein NF-kappa-B essential modulator Non-structural protein 1 Nucleophosmin Nucleoprotein Protein TRS1 Protein Tat RISC-loading complex subunit TARBP2 SH2/SH3 adapter protein NCK1 SUMO-conjugating enzyme UBC9 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Small ubiquitin-related modifier 1 Sphingosine kinase 1 Tyrosine-protein phosphatase non-receptor type 2 Ubiquitin-like protein ISG15 Ubiquitin/ISG15-conjugating enzyme E2 L6 tRNA-dihydrouridine(20) synthase [NAD(P)+]-like	A8MT69 O14920 O14933 O15111 O15287 O15360 O75569 P03418 P03496 P04609 P04637 P05161 P05198 P06493 P06748 P0DMV8 P0DMV9 P11142 P16333 P17706 P19525 P20042 P30153 P30154 P34931 P37840 P40763 P41091 P42224 P52564 P54652 P55265 P62714 P63165 P63279 P67775 Q00597 Q08211 Q0VG06 Q12905 Q12906 Q13217 Q14258 Q15172 Q15633 Q6NZ36 Q6SVX2 Q7Z434 Q8IYD8 Q8N2Z9 Q8NB91 Q9BTP7 Q9HB96 Q9NPI8 Q9NW38 Q9NX74 Q9NYA1 Q9UII4 Q9Y4X5 Q9Y6K9	ADAR ADAR1 APITD1 APRF ARI ARIH1 C17orf70 C19orf40 C1orf86 CDC2 CDC28A CDK1 CDKN1 CEB1 CEBP1 CENPS CENPX CHUK DDX9 DHX9 DNAJC3 DRBF DSRAD DUS2 DUS2L EFP EIF2A EIF2AK2 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 FAA FAAP10 FAAP100 FAAP16 FAAP20 FAAP24 FAC FACA FACC FACE FANCA FANCB FANCC FANCE FANCF FANCG FANCH FANCL FANCM FIP3 G1P1 G1P2 HERC5 HSC70 HSP72 HSP73 HSPA1 HSPA10 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 HSX70 IFI4 IKBKB IKBKG IKKA IKKB ILF2 ILF3 IPS1 ISG15 KIAA1271 KIAA1596 LKP MAP2K6 MAVS MEK6 MHF1 MHF2 MKK6 MOP6 MPHOSPH4 N NACP NCK NCK1 NDH2 NEMO NF45 NF90 NPM NPM1 NS P34CDC2 P53 P58IPK PACT PARK1 PHF9 PKR PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PRKMK6 PRKR PRKRA PRKRI PTPN2 PTPT RAX RNF147 SK1 SKK3 SMT3C SMT3H3 SNCA SPHK SPHK1 SPK STAT1 STAT3 STRA13 SUMO1 TARBP2 TCF16 TP53 TRBP TRIM25 TRS1 UBC9 UBCE9 UBCH7BP UBCH8 UBE2I UBE2L6 UBL1 UCRP VISA XRCC9 ZNF147 tat
Constitutive Signaling by NOTCH1 HD Domain Mutants	Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Neurogenic locus notch homolog protein 1 Polyubiquitin-B Polyubiquitin-C Protein jagged-1 Protein jagged-2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O76050 P0CG47 P0CG48 P46531 P62979 P62987 P78504 P78536 Q86YT6 Q96AX9 Q9NR61 Q9Y219	ADAM10 ADAM17 CSVP DIP1 DLL1 DLL4 JAG1 JAG2 JAGL1 KIAA1323 KUZ MADM MIB1 MIB2 NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH1 RNF67 RPS27A SKD TACE TAN1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2
Activated NOTCH1 Transmits Signal to the Nucleus	Beta-arrestin-1 Beta-arrestin-2 Contactin-1 Delta and Notch-like epidermal growth factor-related receptor Delta-like protein 1 Delta-like protein 4 Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 17 E3 ubiquitin-protein ligase DTX1 E3 ubiquitin-protein ligase DTX4 E3 ubiquitin-protein ligase Itchy homolog E3 ubiquitin-protein ligase MIB1 E3 ubiquitin-protein ligase MIB2 E3 ubiquitin-protein ligase NEURL1 E3 ubiquitin-protein ligase NEURL1B Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 1 Nicastrin Polyubiquitin-B Polyubiquitin-C Presenilin-1 Presenilin-2 Probable E3 ubiquitin-protein ligase DTX2 Protein delta homolog 1 Protein jagged-1 Protein jagged-2 Protein numb homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A8MQ27 O00548 O14672 O76050 P0CG47 P0CG48 P32121 P46531 P49407 P49757 P49768 P49810 P62979 P62987 P78504 P78536 P80370 Q12860 Q86UW9 Q86Y01 Q86YT6 Q8NFT8 Q8WW43 Q92542 Q96AX9 Q96BI3 Q96J02 Q9NR61 Q9NZ42 Q9Y219 Q9Y2E6	AD3 AD4 ADAM10 ADAM17 APH1A APH1B ARB2 ARR1 ARR2 ARRB1 ARRB2 BET C14orf41 CNTN1 CSVP DIP1 DLK DLK1 DLL1 DLL4 DNER DTX1 DTX2 DTX4 ITCH JAG1 JAG2 JAGL1 KIAA0253 KIAA0937 KIAA1323 KIAA1528 KUZ MADM MIB1 MIB2 NCSTN NEURL NEURL1 NEURL1A NEURL1B NEURL3 NOTCH1 NUMB PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 RNF155 RNF58 RNF67 RPS27A SKD STM2 TACE TAN1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZZANK1 ZZANK2

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