GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1351 - 1375** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Chromatin modifications during the maternal to zygotic transition (MZT)	Developmental pluripotency-associated protein 3 E3 ubiquitin-protein ligase UHRF1 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Histone-arginine methyltransferase METTL23 Lysine-specific demethylase 5A Lysine-specific demethylase 5B Lysine-specific demethylase 6A Lysine-specific demethylase 6B Methylcytosine dioxygenase TET3 Protein STPG4 Single-stranded DNA cytosine deaminase Uracil-DNA glycosylase	O15054 O15550 O43151 O60814 P04908 P06899 P0C5Y9 P13051 P16104 P20671 P23527 P29375 P33778 P57053 P58876 P62805 P62807 P68431 P84243 Q16777 Q16778 Q6FI13 Q6W0C5 Q71DI3 Q71UI9 Q86XA0 Q8N257 Q8N801 Q93077 Q93079 Q96A08 Q96T88 Q99877 Q99878 Q99879 Q99880 Q9BTM1 Q9GZX7 Q9UGL1	AICDA AID C17orf95 C2orf61 DGU DPPA3 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 ICBP90 JARID1A JARID1B JMJD3 KDM5A KDM5B KDM6A KDM6B KIAA0346 KIAA0401 METTL23 NP95 PLU1 RBBP2 RBBP2H1 RBP2 RNF106 STELLAR STPG4 TET3 TSH2B UHRF1 UNG UNG1 UNG15 UTX	Homo sapiens (human)
IRE1alpha activates chaperones	Endoplasmic reticulum chaperone BiP Serine/threonine-protein kinase/endoribonuclease IRE1	O75460 P11021	ERN1 GRP78 HSPA5 IRE1	Homo sapiens (human)
CDC42 GTPase cycle	ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Actin nucleation-promoting factor WAS Actin nucleation-promoting factor WASL Active breakpoint cluster region-related protein Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 BAR/IMD domain-containing adapter protein 2 BTB/POZ domain-containing protein KCTD3 Breakpoint cluster region protein CDC42 small effector protein 2 Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 2 Cdc42 effector protein 3 Cdc42 effector protein 4 Cdc42 effector protein 5 Cell division control protein 42 homolog Copine-8 DEP domain-containing protein 1B Dedicator of cytokinesis protein 10 Dedicator of cytokinesis protein 11 Dedicator of cytokinesis protein 6 Dedicator of cytokinesis protein 7 Dedicator of cytokinesis protein 8 Dedicator of cytokinesis protein 9 Delta(14)-sterol reductase LBR Differentially expressed in FDCP 6 homolog Disheveled-associated activator of morphogenesis 1 Dynamin-binding protein Ephexin-1 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 1 FYVE, RhoGEF and PH domain-containing protein 2 FYVE, RhoGEF and PH domain-containing protein 3 FYVE, RhoGEF and PH domain-containing protein 4 Formin-binding protein 1-like Formin-binding protein 1 Formin-like protein 1 Formin-like protein 2 Formin-like protein 3 GEM-interacting protein Golgin subfamily A member 8R Guanine nucleotide exchange factor DBS Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 Guanine nucleotide-binding protein subunit alpha-13 Inactive Rho GTPase-activating protein 11B Intersectin-1 Junction plakoglobin Kinectin Lamina-associated polypeptide 2, isoforms beta/gamma Metalloreductase STEAP3 Mitogen-activated protein kinase kinase kinase 11 N-chimaerin Oligophrenin-1 Partitioning defective 6 homolog alpha Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phospholipase D1 Pleckstrin homology domain-containing family G member 1 Pleckstrin homology domain-containing family G member 2 Pleckstrin homology domain-containing family G member 3 Pleckstrin homology domain-containing family G member 4B Protein ECT2 Protein FAM13B Protein diaphanous homolog 3 Protein scribble homolog Proto-oncogene DBL Puratrophin-1 Rac GTPase-activating protein 1 Ragulator complex protein LAMTOR1 RalA-binding protein 1 Ras GTPase-activating-like protein IQGAP1 Ras GTPase-activating-like protein IQGAP2 Ras GTPase-activating-like protein IQGAP3 Ras-related protein Rab-7a Ras-specific guanine nucleotide-releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 2 Rho GDP-dissociation inhibitor 3 Rho GTPase-activating protein 10 Rho GTPase-activating protein 17 Rho GTPase-activating protein 1 Rho GTPase-activating protein 20 Rho GTPase-activating protein 21 Rho GTPase-activating protein 22 Rho GTPase-activating protein 24 Rho GTPase-activating protein 26 Rho GTPase-activating protein 27 Rho GTPase-activating protein 29 Rho GTPase-activating protein 30 Rho GTPase-activating protein 31 Rho GTPase-activating protein 32 Rho GTPase-activating protein 33 Rho GTPase-activating protein 35 Rho GTPase-activating protein 39 Rho GTPase-activating protein 40 Rho GTPase-activating protein 42 Rho GTPase-activating protein 44 Rho GTPase-activating protein 45 Rho GTPase-activating protein 4 Rho GTPase-activating protein 5 Rho GTPase-activating protein 7 Rho GTPase-activating protein 9 Rho GTPase-activating protein SYDE1 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 4 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho guanine nucleotide exchange factor TIAM1 SH3 and PX domain-containing protein 2A SH3KBP1-binding protein 1 SLIT-ROBO Rho GTPase-activating protein 1 SLIT-ROBO Rho GTPase-activating protein 2 SLIT-ROBO Rho GTPase-activating protein 3 Serine/threonine-protein kinase MRCK alpha Serine/threonine-protein kinase MRCK beta Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase PAK 4 Serine/threonine-protein kinase PAK 5 Serine/threonine-protein kinase PAK 6 Spermatogenesis-associated protein 13 StAR-related lipid transfer protein 13 StAR-related lipid transfer protein 8 Stomatin Synaptobrevin homolog YKT6 Synaptosomal-associated protein 23 T-cell activation Rho GTPase-activating protein Transferrin receptor protein 1 Triple functional domain protein Unconventional myosin-IXb Vang-like protein 1 Vesicle-associated membrane protein 3 WAS/WASL-interacting protein family member 1 WAS/WASL-interacting protein family member 2 WAS/WASL-interacting protein family member 3 WD repeat-containing protein 81 WD repeat-containing protein 91	A1A4S6 A1L390 A4D1P6 A6NGB9 A6NI28 A7KAX9 I6L899 O00161 O00401 O00459 O14559 O14613 O14827 O15013 O15068 O15085 O15498 O43295 O43307 O43516 O60890 O75044 O75914 O75962 O94989 O95466 O96013 P02786 P10911 P11274 P14923 P15882 P27105 P27986 P42167 P42768 P46940 P51149 P52565 P52566 P52735 P60953 P98171 P98174 Q00587 Q03135 Q07960 Q12774 Q12979 Q13009 Q13017 Q13153 Q13177 Q13393 Q13459 Q13576 Q14155 Q14160 Q14161 Q14344 Q14739 Q15052 Q15311 Q15811 Q15836 Q16584 Q17R89 Q2M1Z3 Q3KRB8 Q52LW3 Q562E7 Q58EX7 Q5JSL3 Q5JSP0 Q5T0N5 Q5T5U3 Q5TCZ1 Q5TG30 Q5VT25 Q5VV41 Q658P3 Q68EM7 Q6IAA8 Q6NZY7 Q6XZF7 Q6ZUM4 Q6ZW31 Q70Z35 Q7Z5H3 Q7Z6B7 Q7Z6I6 Q7Z6J4 Q86UP2 Q86VI3 Q86VW2 Q86YQ8 Q8IVF7 Q8IW93 Q8N103 Q8N264 Q8N5V2 Q8N6H7 Q8NF50 Q8TAA9 Q8TBC3 Q8TCU6 Q8TF74 Q8WUY9 Q8WWN8 Q8WZ64 Q92502 Q92619 Q96BY6 Q96DR7 Q96HP0 Q96M96 Q96N67 Q96N96 Q96P48 Q96PX9 Q96PY5 Q96QB1 Q96RU3 Q99819 Q9BRR9 Q9BZ29 Q9C0H5 Q9H0H5 Q9H3Q1 Q9H4E7 Q9H7P9 Q9H8V3 Q9NP61 Q9NPB6 Q9NQU5 Q9NR80 Q9NRR3 Q9NRY4 Q9NSV4 Q9NYF5 Q9NZN5 Q9P107 Q9P286 Q9P2F6 Q9UKI2 Q9UKW4 Q9ULL1 Q9UNA1 Q9UQB8 Q9Y2X7 Q9Y3M8 Q9Y4D1 Q9Y4F1 Q9Y597 Q9Y5S2	ABR ARAP1 ARAP2 ARAP3 ARFGAP1 ARFGAP2 ARFGAP3 ARHDH9 ARHGAP1 ARHGAP10 ARHGAP11B ARHGAP13 ARHGAP14 ARHGAP17 ARHGAP2 ARHGAP20 ARHGAP21 ARHGAP22 ARHGAP24 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP34 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP40 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP7 ARHGAP9 ARHGDIA ARHGDIB ARHGDIG ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF19 ARHGEF25 ARHGEF26 ARHGEF36 ARHGEF4 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 BAIAP2 BCR BCR1 BND7 BORG1 BORG2 BORG3 BORG4 BORG5 C11orf59 C17orf1 C17orf1B C1orf39 C20orf95 C5orf5 CAMGAP1 CAV CAV1 CDC42 CDC42BPA CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CDC42GAP CDC42SE2 CDEP CDGAP CENTD1 CENTD2 CENTD3 CEP1 CEP2 CEP3 CEP4 CEP5 CG1 CHN CHN1 COOL1 COOL2 CPNE8 CR16 CRIB1 CTNNG D22S11 DAAM1 DBL DEF6 DEPDC1B DEPDC2 DIAP3 DIAPH3 DLC1 DLC2 DLC3 DNMBP DOCK10 DOCK11 DOCK6 DOCK7 DOCK8 DOCK9 DP3 ECT2 EPB72 EPHEXIN4 FAM13B FAM13B1 FAM7B1 FARP1 FBP17 FGD1 FGD2 FGD3 FGD4 FGDY FHOD2 FHOD3 FILGAP FISH FMNL FMNL1 FMNL2 FMNL3 FNBP1 FNBP1L FNBP2 FRABP FRL1 FRL2 GDIA1 GDIA2 GDID4 GEFT GIT1 GIT2 GMIP GNA13 GOLGA8R GRAF GRAF2 GRAF3 GRB1 GRF1 GRF2 GRIT GRLF1 GT650 HMHA1 IBP IMD2 IQGAP1 IQGAP2 IQGAP3 ITSN ITSN1 JUP KCTD3 KIAA0004 KIAA0006 KIAA0051 KIAA0131 KIAA0142 KIAA0147 KIAA0148 KIAA0189 KIAA0223 KIAA0294 KIAA0362 KIAA0380 KIAA0382 KIAA0411 KIAA0418 KIAA0424 KIAA0451 KIAA0456 KIAA0554 KIAA0580 KIAA0599 KIAA0621 KIAA0666 KIAA0672 KIAA0694 KIAA0712 KIAA0782 KIAA0915 KIAA1010 KIAA1058 KIAA1112 KIAA1124 KIAA1142 KIAA1156 KIAA1204 KIAA1209 KIAA1264 KIAA1304 KIAA1391 KIAA1395 KIAA1415 KIAA1424 KIAA1478 KIAA1688 KIAA1722 KIAA1723 KIAA1771 KIAA1902 KIAA1909 KIAA2014 KTN1 LAMTOR1 LAP2 LAP4 LARG LBR MAP3K11 MCF2 MCF2L MEGAP MGCRACGAP MLK3 MSE55 MYO9B MYR5 NBR NGEF OPHN1 OPHN1L OPHN3 OST P190A P85SPR PAK1 PAK2 PAK3 PAK3BP PAK4 PAK5 PAK6 PAK7 PAR6A PARD6A PARG1 PDRO PIK3R1 PIK3R2 PIXA PIXB PLD1 PLEKHC2 PLEKHG1 PLEKHG2 PLEKHG3 PLEKHG4 PLEKHG4B PREX1 PREX2 PRTPHN1 PTK1 RAB7 RAB7A RACGAP1 RALBP1 RAP1GN1 RASGRF2 RGC1 RHOGAP1 RHOGAP2 RHOGAP4 RHOGAP5 RICH1 RICH2 RICS RLIP RLIP1 RLIP76 SB1 SCRB1 SCRIB SGEF SH3D1A SH3D20 SH3MD1 SH3PXD2A SHKBP1 SNAP23 SNX26 SPATA13 SPEC2 SPRK SRGAP1 SRGAP2 SRGAP2A SRGAP3 STARD12 STARD13 STARD8 STB2 STEAP3 STOM SYB3 SYDE1 TAGAP TAGAP1 TCGAP TFRC TIAM1 TIM TKS5 TMEM133 TMPO TOCA1 TRIO TSAP6 TUBA VAMP3 VANGL1 VARTUL VAV2 VAV3 WAS WASL WASPIP WBP3 WDR81 WDR91 WICH WIP WIPF1 WIPF2 WIPF3 WIRE XTP8 YKT6 ZFYVE3 ZFYVE4 ZFYVE5 ZFYVE6 ZIZ1 ZIZ2 ZIZ3 ZNF289 p190ARHOGAP	Homo sapiens (human)
p75NTR negatively regulates cell cycle via SC1	Beta-nerve growth factor Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 PR domain zinc finger protein 4 Tumor necrosis factor receptor superfamily member 16	O15379 P01138 P08138 Q13547 Q92769 Q9UKN5	HDAC1 HDAC2 HDAC3 NGF NGFB NGFR PFM1 PRDM4 RPD3L1 TNFRSF16	Homo sapiens (human)
Regulation of signaling by NODAL	Activin receptor type-1B Activin receptor type-1C Activin receptor type-2A Activin receptor type-2B Cerberus Cryptic protein DAN domain family member 5 Left-right determination factor 1 Left-right determination factor 2 Nodal homolog Protein Cripto Putative protein CRIPTO3	O00292 O75610 O95813 P0CG37 P13385 P27037 P36896 P51864 Q13705 Q8N907 Q8NER5 Q96S42	ACVR1B ACVR1C ACVR2 ACVR2A ACVR2B ACVRLK4 ALK4 ALK7 CER1 CER2 CFC1 CKTSF1B3 CRIPTO CRIPTO-1 CRIPTO-3 CRIPTO3 DAND4 DAND5 EBAF GREM3 LEFTA LEFTB LEFTY1 LEFTY2 LEFTYA LEFTYB NODAL SP1 TDGF1 TDGF1P3 TDGF2 TDGF3 TGFB4	Homo sapiens (human)
Class C/3 (Metabotropic glutamate/pheromone receptors)	Extracellular calcium-sensing receptor G-protein coupled receptor family C group 6 member A Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor 3 Metabotropic glutamate receptor 4 Metabotropic glutamate receptor 5 Metabotropic glutamate receptor 6 Metabotropic glutamate receptor 7 Metabotropic glutamate receptor 8 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 19 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 42 Taste receptor type 2 member 43 Taste receptor type 2 member 45 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 60 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Taste receptor type 2 member 9	O00222 O15303 O75899 P41180 P41594 P59533 P59534 P59535 P59536 P59537 P59538 P59539 P59540 P59541 P59542 P59543 P59544 P59551 Q13255 Q14416 Q14831 Q14832 Q14833 Q5T6X5 Q7RTR8 Q7RTX0 Q7RTX1 Q8TE23 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW1 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9UBS5	CASR GABBR1 GABBR2 GPR51 GPR59 GPR60 GPR70 GPR71 GPRC1A GPRC1B GPRC1C GPRC1D GPRC1E GPRC1F GPRC1G GPRC1H GPRC2A GPRC3A GPRC3B GPRC6A GRM1 GRM2 GRM3 GRM4 GRM5 GRM6 GRM7 GRM8 MGLUR1 MGLUR2 MGLUR3 MGLUR4 MGLUR5 MGLUR6 MGLUR7 MGLUR8 PCAR1 PTC T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R19 TAS2R20 TAS2R23 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R42 TAS2R43 TAS2R44 TAS2R45 TAS2R46 TAS2R47 TAS2R48 TAS2R49 TAS2R5 TAS2R50 TAS2R55 TAS2R60 TAS2R7 TAS2R8 TAS2R9 TR1 TR2 TR3	Homo sapiens (human)	G58161NS
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	Amphiregulin Apoptosis regulator Bcl-2 Cyclin-dependent kinase inhibitor 1B ETS domain-containing protein Elk-1 Epidermal growth factor receptor Epigen Exportin-1 Focal adhesion kinase 1 Forkhead box protein O3 G1/S-specific cyclin-D1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein c-Fos Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein kinase Kist Serum response factor	O14944 O14980 O43524 P00533 P01100 P01133 P01135 P10415 P11831 P15514 P19419 P24385 P27361 P28482 P31749 P31751 P35070 P46527 Q05397 Q6UW88 Q8TAS1 Q99075 Q9Y243	AKT1 AKT2 AKT3 AREG AREGB BCL1 BCL2 BTC CCND1 CDKN1B CRM1 DTR DTS EGF EGFR ELK1 EPGN ERBB ERBB1 EREG ERK1 ERK2 FAK FAK1 FKHRL1 FOS FOXO3 FOXO3A G0S7 HBEGF HEGFL HER1 KIP1 KIS KIST MAPK1 MAPK3 PKB PKBG PRAD1 PRKM1 PRKM2 PRKM3 PTK2 RAC SDGF SRF TGFA UHMK1 XPO1 p27	Homo sapiens (human)
Tryptophan catabolism	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase 3-hydroxyanthranilate 3,4-dioxygenase Amino acid transporter heavy chain SLC3A2 Indoleamine 2,3-dioxygenase 1 Indoleamine 2,3-dioxygenase 2 Kynureninase Kynurenine 3-monooxygenase Kynurenine formamidase Kynurenine--oxoglutarate transaminase 1 Kynurenine--oxoglutarate transaminase 3 Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial Large neutral amino acids transporter small subunit 1 Neutral amino acid uniporter 4 Tryptophan 2,3-dioxygenase	O15229 P08195 P14902 P46952 P48775 Q01650 Q16719 Q16773 Q63HM1 Q6YBV0 Q6YP21 Q6ZQW0 Q8N5Z0 Q8TDX5	AADAT ACMSD AFMID CCBL1 CCBL2 CD98LC HAAO IDO IDO1 IDO2 INDO INDOL1 KAT2 KAT3 KMO KYAT1 KYAT2 KYAT3 KYNU LAT1 MDU1 MPE16 PAT4 SLC36A4 SLC3A2 SLC7A5 TDO TDO2	Homo sapiens (human)
Signaling by FLT3 fusion proteins	Cyclin-dependent kinase inhibitor 1 GRB2-associated-binding protein 2 GTPase HRas GTPase NRas Golgin subfamily B member 1 NADPH oxidase 4 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Serine/threonine-protein kinase pim-1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Son of sevenless homolog 1 Spectrin beta chain, non-erythrocytic 1 Thyroid receptor-interacting protein 11 Transcription factor ETV6 Unconventional myosin-XVIIIa Zinc finger MYM-type protein 2	P01111 P01112 P11309 P27986 P38936 P41212 P42229 P42336 P51692 Q01082 Q07889 Q14789 Q15643 Q92614 Q9NPH5 Q9UBW7 Q9UQC2	CAP20 CD245 CDKN1 CDKN1A CEV14 CIP1 ETV6 FIM GAB2 GOLGB1 GRB1 HRAS HRAS1 KIAA0216 KIAA0571 MDA6 MYO18A MYSPDZ NOX4 NRAS PIC1 PIK3CA PIK3R1 PIM1 RAMP RENOX SDI1 SOS1 SPTB2 SPTBN1 STAT5 STAT5A STAT5B TEL TEL1 TIAF1 TRIP11 WAF1 ZMYM2 ZNF198	Homo sapiens (human)
RUNX2 regulates genes involved in differentiation of myeloid cells	Core-binding factor subunit beta Galectin-3 Runt-related transcription factor 1	P17931 Q01196 Q13951	AML1 CBFA2 CBFB LGALS3 MAC2 RUNX1	Homo sapiens (human)
RNA Polymerase II Transcription Initiation	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 TATA-binding protein-associated factor 2N TATA-box-binding protein Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B	O00268 O15514 P13984 P18074 P19387 P19388 P19447 P20226 P21675 P24928 P29083 P29084 P30876 P32780 P35269 P36954 P49848 P50613 P51946 P51948 P52434 P52435 P52655 P52657 P53803 P61218 P62487 P62875 Q00403 Q12962 Q13888 Q13889 Q15542 Q15543 Q15544 Q15545 Q16514 Q16594 Q5H9L4 Q5VWG9 Q6P1X5 Q6ZYL4 Q8IZX4 Q92750 Q92759 Q92804 Q9HBM6	BA2R BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCG1 CCGS CCNH CDK7 CDKN7 CIF150 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2D1 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MAT1 MNAT1 MO15 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RBP56 RNF66 RPB7 STK1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TBP TF2A1 TF2A2 TF2B TF2D TF2E1 TF2E2 TFIIB TFIID TTDA XPB XPBC XPD XPDC	Homo sapiens (human)
Signaling by activated point mutants of FGFR3	Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 4 Fibroblast growth factor 9 Fibroblast growth factor receptor 3	O43320 O76093 P05230 P08620 P09038 P22607 P31371 Q9GZV9 Q9NP95	FGF1 FGF16 FGF18 FGF2 FGF20 FGF23 FGF4 FGF9 FGFA FGFB FGFR3 HST HSTF1 HYPF JTK4 KS3	Homo sapiens (human)
Ciprofloxacin ADME	Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Organic anion transporter 3 Solute carrier family 22 member 1 Solute carrier organic anion transporter family member 1A2	O15245 P02768 P46721 Q8TCC7 Q9UNQ0	ABCG2 ABCP ALB BCRP BCRP1 MXR OAT3 OATP OATP1 OATP1A2 OCT1 SLC21A3 SLC22A1 SLC22A8 SLCO1A2	Homo sapiens (human)
Protein methylation	Calmodulin-1 Calmodulin-lysine N-methyltransferase DNA/RNA-binding protein KIN17 EEF1A lysine methyltransferase 1 EEF1A lysine methyltransferase 2 Electron transfer flavoprotein beta subunit lysine methyltransferase Electron transfer flavoprotein subunit beta Elongation factor 1-alpha 1 Elongation factor 2 Heat shock cognate 71 kDa protein Methyltransferase-like protein 22 Protein N-lysine methyltransferase METTL21A Protein N-lysine methyltransferase METTL21D Protein arginine N-methyltransferase 3 Protein-lysine N-methyltransferase EEF2KMT Small ribosomal subunit protein uS5 Transitional endoplasmic reticulum ATPase	O60678 O60870 P0DP23 P11142 P13639 P15880 P38117 P55072 P68104 Q5JPI9 Q7Z624 Q8IXQ9 Q8WVE0 Q8WXB1 Q96G04 Q9BUU2 Q9H867	BTCD C10orf138 C12orf72 C14orf138 C16orf68 C2orf34 CALM CALM1 CAM CAM1 CAMKMT CLNMT EEF1A EEF1A1 EEF1AKMT1 EEF1AKMT2 EEF2 EEF2KMT EF1A EF2 ETFB ETFBKMT FAM119A FAM86A HCA557B HEL-220 HEL-S-70 HRMT1L3 HSC70 HSP73 HSPA10 HSPA8 KIN KIN17 LENG7 METTL10 METTL20 METTL21A METTL21D METTL22 N6AMT2 PRMT3 RPS2 RPS4 VCP VCPKMT	Homo sapiens (human)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 M-phase inducer phosphatase 1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Serine/threonine-protein kinase Chk1 Serine/threonine-protein kinase Chk2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14757 O14818 O43242 O96017 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30304 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q13200 Q15008 Q16186 Q99436 Q99460 Q9UNM6	ADRM1 C7orf76 CDC25A CDS1 CHEK1 CHEK2 CHK1 CHK2 DSS1 GP110 HC2 HC3 HC8 HC9 HSPC KIAA0107 LMPX LMPY MB1 MIP224 MOV34L MSS1 NU PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RAD53 RPS27A SEM1 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	Inhibitor of nuclear factor kappa-B kinase subunit epsilon Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Optineurin Polyubiquitin-B Polyubiquitin-C Serine/threonine-protein kinase TBK1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 TNF receptor-associated factor 3 TRAF family member-associated NF-kappa-B activator Toll-like receptor 4 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00206 P08571 P0CG47 P0CG48 P62979 P62987 Q13114 Q14164 Q86XR7 Q8IUC6 Q92844 Q96CV9 Q9UHD2 Q9Y6Y9	CAP-1 CD14 CRAF1 ESOP1 FIP2 GLC1E HIP7 HYPL IKBKE IKKE IKKI ITRAF KIAA0151 LY96 MD2 NAK NRP OPTN PRVTIRB RPS27A TANK TBK1 TICAM1 TICAM2 TIRAP3 TIRP TLR4 TRAF2 TRAF3 TRAFAMN TRAM TRIF UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Synthesis of IPs in the nucleus	Inositol hexakisphosphate kinase 1 Inositol hexakisphosphate kinase 2 Inositol polyphosphate multikinase Inositol-pentakisphosphate 2-kinase	Q8NFU5 Q92551 Q9H8X2 Q9UHH9	C9orf12 IHPK1 IHPK2 IMPK IP6K1 IP6K2 IPMK IPPK KIAA0263	Homo sapiens (human)
Detoxification of Reactive Oxygen Species	Aquaporin-8 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Copper chaperone for superoxide dismutase Copper transport protein ATOX1 Copper-transporting ATPase 1 Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c ERO1-like protein alpha Epididymal secretory glutathione peroxidase Extracellular superoxide dismutase [Cu-Zn] Glutathione S-transferase P Glutathione peroxidase 1 Glutathione peroxidase 2 Glutathione peroxidase 3 Glutathione peroxidase 6 Glutathione peroxidase 7 NADPH oxidase 4 NADPH oxidase 5 Neutrophil cytosol factor 1 Neutrophil cytosol factor 2 Neutrophil cytosol factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-6 Probable glutathione peroxidase 8 Protein disulfide-isomerase Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	O00244 O14618 O75715 O94778 P00441 P04040 P04179 P04839 P07203 P07237 P08294 P09211 P10599 P13498 P14598 P18283 P19878 P22352 P30041 P30048 P32119 P50583 P59796 P99999 Q04656 Q06830 Q15080 Q16881 Q8TED1 Q96HE7 Q96PH1 Q96SL4 Q99757 Q9NNW7 Q9NPH5	AOP1 AOP2 APAH1 AQP8 ATOX1 ATP7A CAT CCS CYBA CYBB CYC CYCS ERBA2L ERO1A ERO1L FAEES3 GPX1 GPX2 GPX3 GPX5 GPX6 GPX7 GPX8 GPXP GRIM12 GST3 GSTP1 HAH1 KDRF KIAA0106 KIAA1652 MC1 MNK NCF1 NCF2 NCF4 NKEFB NOX2 NOX4 NOX5 NOXA2 NOXO2 NUDT2 P4HB P67PHOX PAGA PAGB PDI PDIA1 PO4DB PRDX1 PRDX2 PRDX3 PRDX6 RENOX SH3PXD1A SH3PXD4 SOD1 SOD2 SOD3 TDPX1 TDPX2 TRDX TRX TRX1 TRX2 TRXR2 TXN TXN2 TXNRD1 TXNRD2	Homo sapiens (human)
Defective F8 binding to von Willebrand factor	Coagulation factor VIII von Willebrand factor	P00451 P04275	F8 F8C F8VWF VWF	Homo sapiens (human)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Amphiregulin B-lymphocyte antigen CD19 BDNF/NT-3 growth factors receptor Beta-klotho Brain-derived neurotrophic factor Epidermal growth factor receptor Epigen Estrogen receptor beta Estrogen receptor Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin Interleukin-1 receptor-associated kinase 1 Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-like 1 Interleukin-33 Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myeloid differentiation primary response protein MyD88 NT-3 growth factor receptor Neurotrophin-3 Neurotrophin-4 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphoinositide 3-kinase adapter protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Protransforming growth factor alpha RAC-alpha serine/threonine-protein kinase Radiation-inducible immediate-early gene IEX-1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Rho-related GTP-binding protein RhoG Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Striatin T-cell receptor-associated transmembrane adapter 1 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 TNF receptor-associated factor 6 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 11	O00329 O00459 O14511 O14944 O14986 O15520 O43320 O43815 O60331 O76093 O95750 O95760 P00533 P01127 P01133 P01135 P01308 P03372 P04626 P05230 P06213 P06239 P06241 P08581 P08620 P09038 P09619 P10721 P10747 P10767 P11487 P12931 P14210 P15153 P15391 P15498 P15514 P16234 P20783 P21781 P22455 P23560 P27361 P27986 P28482 P30153 P30154 P31371 P31749 P33681 P34130 P35070 P35568 P36888 P42081 P42336 P42338 P46695 P48426 P49771 P51617 P56975 P62714 P63000 P67775 P78356 P84095 Q01638 Q02297 Q06124 Q13362 Q13480 Q14738 Q15172 Q15173 Q16288 Q16537 Q16620 Q6PIZ9 Q6UW88 Q6ZUJ8 Q86Z14 Q8TBX8 Q8WU20 Q8WWG1 Q92569 Q92731 Q99075 Q99755 Q99836 Q9GZV9 Q9HCT0 Q9NP95 Q9NWZ3 Q9UQC2 Q9Y4H2 Q9Y4K3	AKT1 AREG AREGB ARHG BCAP BDNF BTC C9orf26 CD135 CD19 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 DER4 DIF2 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ERK1 ERK2 ESR ESR1 ESR2 ESTRB FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GGF GRB1 HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRGA HST HST2 HSTF1 HSTF2 HYPF IER3 IEX1 IL1F11 IL1RL1 IL33 INS INSR INT2 IRAK IRAK1 IRAK4 IRS1 IRS2 JTK2 KGF KIAA0044 KIAA0571 KIAA0589 KIT KLB KS3 LAB7 LCK MAPK1 MAPK3 MET MLN19 MYD88 NDF NEU NFHEV NGL NR3A1 NR3A2 NRG1 NRG2 NRG3 NRG4 NTAK NTF3 NTF4 NTF5 NTRK2 NTRK3 PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PI5P4KA PIK3AP1 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PIP5K2 PIP5K2A PIP5K2B PIP5K2C PKB PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PRG1 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RAC RAC1 RAC2 RHEPDGFRA RHOG RNF85 SCFR SDGF SHPTP2 SIS SMDF SRC SRC1 ST2 STK1 STM7 STRN T1 TC25 TCRIM TGFA TKF TRAF6 TRAT1 TRKB TRKC VAV VAV1	Homo sapiens (human)
Vitamin B5 (pantothenate) metabolism	4'-phosphopantetheine phosphatase Autotaxin Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 Fatty acid synthase L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mitochondrial coenzyme A diphosphatase NUDT8 Mitochondrial coenzyme A transporter SLC25A42 PDZ domain-containing protein 11 Pantetheinase Pantetheine hydrolase VNN2 Sodium-dependent multivitamin transporter Solute carrier family 25 member 16	O14638 O95497 O95498 P16260 P22413 P49327 Q13822 Q5EBL8 Q86VD7 Q8WV74 Q9NRN7 Q9NVE7 Q9Y289	AASDHPPT AIPP1 ATX ENPP1 ENPP2 ENPP3 FAS FASN GDA M6S1 NPPS NUDT8 PANK4 PC1 PDNP1 PDNP2 PDNP3 PDZD11 PDZK11 PISP SLC25A16 SLC25A42 SLC5A6 SMVT VNN1 VNN2	Homo sapiens (human)
Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH)	Sodium/hydrogen exchanger 6	Q92581	KIAA0267 NHE6 SLC9A6	Homo sapiens (human)
Major pathway of rRNA processing in the nucleolus and cytosol	18S rRNA (guanine-N(7))-methyltransferase 3'-5' exoribonuclease 1 5'-3' exoribonuclease 2 60S ribosome subunit biogenesis protein NIP7 homolog Bystin Casein kinase I isoform delta Casein kinase I isoform epsilon DDB1- and CUL4-associated factor 13 Exosome RNA helicase MTR4 Exosome complex component 10 Exosome complex component CSL4 Exosome complex component MTR3 Exosome complex component RRP40 Exosome complex component RRP41 Exosome complex component RRP42 Exosome complex component RRP43 Exosome complex component RRP45 Exosome complex component RRP46 Exosome complex component RRP4 Exosome complex exonuclease RRP44 Guanine nucleotide-binding protein-like 3 HEAT repeat-containing protein 1 Interferon-stimulated 20 kDa exonuclease-like 2 KRR1 small subunit processome component homolog Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 M-phase phosphoprotein 6 NHP2-like protein 1 Nuclear nucleic acid-binding protein C1D Nucleolar RNA helicase 2 Nucleolar complex protein 4 homolog Nucleolar protein 11 Nucleolar protein 12 Nucleolar protein 14 Nucleolar protein 56 Nucleolar protein 58 Nucleolar protein 6 Nucleolin Periodic tryptophan protein 2 homolog Pescadillo homolog Polynucleotide 5'-hydroxyl-kinase NOL9 Pre-rRNA-processing protein TSR1 homolog Probable ATP-dependent RNA helicase DDX47 Probable ATP-dependent RNA helicase DDX49 Probable ATP-dependent RNA helicase DDX52 Probable ATP-dependent RNA helicase DHX37 Probable U3 small nucleolar RNA-associated protein 11 Probable rRNA-processing protein EBP2 Proline-, glutamic acid- and leucine-rich protein 1 Protein LTV1 homolog Protein RRP5 homolog RNA 3'-terminal phosphate cyclase-like protein RNA-binding protein 28 RNA-binding protein NOB1 RNA-binding protein PNO1 Ribonuclease P protein subunit p14 Ribonuclease P protein subunit p21 Ribonuclease P protein subunit p25 Ribonuclease P protein subunit p30 Ribonuclease P protein subunit p38 Ribonuclease P protein subunit p40 Ribosomal RNA processing protein 1 homolog A Ribosomal RNA processing protein 36 homolog Ribosomal RNA small subunit methyltransferase NEP1 Ribosomal RNA-processing protein 7 homolog A Ribosomal biogenesis protein LAS1L Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Ribosome biogenesis protein BMS1 homolog Ribosome biogenesis protein BOP1 Ribosome biogenesis protein WDR12 Sentrin-specific protease 3 Serine/threonine-protein kinase RIO1 Serine/threonine-protein kinase RIO2 Serine/threonine-protein kinase RIO3 Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Small subunit processome component 20 homolog Something about silencing protein 10 Testis-expressed protein 10 Transducin beta-like protein 3 U3 small nucleolar RNA-associated protein 14 homolog A U3 small nucleolar RNA-associated protein 14 homolog C U3 small nucleolar RNA-associated protein 15 homolog U3 small nucleolar RNA-associated protein 18 homolog U3 small nucleolar RNA-associated protein 25 homolog U3 small nucleolar RNA-associated protein 4 homolog U3 small nucleolar RNA-associated protein 6 homolog U3 small nucleolar RNA-interacting protein 2 U3 small nucleolar ribonucleoprotein protein IMP3 U3 small nucleolar ribonucleoprotein protein IMP4 U3 small nucleolar ribonucleoprotein protein MPP10 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat-containing protein 18 WD repeat-containing protein 36 WD repeat-containing protein 3 WD repeat-containing protein 43 WD repeat-containing protein 46 WD repeat-containing protein 75 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 rRNA 2'-O-methyltransferase fibrillarin rRNA-processing protein FCF1 homolog	O00541 O00566 O00567 O14730 O15213 O43709 O43818 O75691 O75818 O95059 P05386 P05387 P05388 P08708 P08865 P15880 P18077 P18124 P18621 P19338 P22087 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P36578 P39019 P39023 P40429 P42285 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P48730 P49207 P49674 P50914 P55769 P56182 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P78316 P78345 P78346 P83731 P83881 P84098 Q01780 Q02543 Q02878 Q06265 Q07020 Q12788 Q13601 Q13868 Q13895 Q13901 Q14137 Q14690 Q14692 Q15024 Q15061 Q15269 Q2NL82 Q5RKV6 Q5SY16 Q5TAP6 Q68CQ4 Q6P5R6 Q71UM5 Q8IV48 Q8IWA0 Q8IY37 Q8IY81 Q8IZL8 Q8NI36 Q8TD47 Q8TED0 Q92901 Q92979 Q969Q0 Q969X6 Q96B26 Q96EH5 Q96EU6 Q96G21 Q96GA3 Q96L21 Q99547 Q99848 Q9BRS2 Q9BUL9 Q9BV38 Q9BVI4 Q9BVJ6 Q9BVP2 Q9BVS4 Q9GZL7 Q9H0D6 Q9H0S4 Q9H4L4 Q9H583 Q9H633 Q9H6R4 Q9H8H0 Q9H9L3 Q9NPD3 Q9NQT4 Q9NQT5 Q9NQZ2 Q9NR30 Q9NRX1 Q9NV06 Q9NV31 Q9NW13 Q9NXF1 Q9NYH9 Q9UGY1 Q9ULX3 Q9UNX3 Q9UNX4 Q9Y221 Q9Y2L1 Q9Y2P8 Q9Y2R4 Q9Y2X3 Q9Y324 Q9Y3A2 Q9Y3A4 Q9Y3B2 Q9Y3U8 Q9Y4W2 Q9Y5J1 Q9Y6V7	3'EXO ART4 BAP28 BBC1 BING4 BMS1 BMS1L BOP1 BUD23 BXDC4 BYSL C14orf111 C15orf12 C17orf40 C1D C1orf107 C2F C4orf9 C6orf11 C6orf135 C6orf153 C6orf93 CAT60 CCG2 CIRH1A CML28 CRLZ1 CSL4 CSNK1D CSNK1E D11S2243E D21S2056E D6S218E DCAF13 DDX21 DDX37 DDX47 DDX49 DDX52 DEF DHX37 DIEXF DIS3 DOB1 DRIM DXS648E E2IG3 EBNA1BP2 EBP2 EC45 EMG1 ENP1 ERI1 EXOSC1 EXOSC10 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FAU FBL FCF1 FIB1 FLRN FTE1 FTSJ3 GNL3 HCA66 HCKID HEATR1 HMX3 HRB2 IMP3 IMP4 ISG20L2 KIAA0007 KIAA0052 KIAA0116 KIAA0124 KIAA0185 KIAA0187 KIAA0266 KIAA1008 KIAA1401 KIAA1517 KIAA1988 KRR1 LAMBR LAMR1 LAS1L LTV1 MERM1 MFTL MHAT MNAR MPHOSPH10 MPHOSPH6 MPP10 MPP6 MPS1 MRPS4 MTR3 MTR4 MTREX NCL NEDD6 NHP2L1 NIP7 NNP1 NOB1 NOB1P NOC4L NOL11 NOL12 NOL14 NOL5 NOL5A NOL6 NOL9 NOP14 NOP5 NOP52 NOP56 NOP58 NS OIP2 PDCD11 PELP1 PES1 PMSCL PMSCL1 PMSCL2 PNO1 PSMD8BP1 PWP2 PWP2H QM RBM28 RCL1 RIG RIO1 RIO2 RIOK1 RIOK2 RIOK3 RNAC RNASEP1 RNASEP2 RNU3IP2 ROK1 RPC2 RPCL1 RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP14 RPP2 RPP21 RPP25 RPP30 RPP38 RPP40 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 RRP1A RRP36 RRP4 RRP40 RRP41 RRP42 RRP43 RRP44 RRP46 RRP6 RRP7A RRP9 RTC2 SAS10 SAZD SCAR SDCCAG16 SENP3 SKI6 SKIV2L2 SNU13 SSP3 SUDD SURF-3 SURF3 SUSP3 TBL3 TEX10 THEX1 TSR1 TXREB1 U355K UBA52 UBA80 UBCEP1 UBCEP2 UTP10 UTP11 UTP11L UTP14A UTP14C UTP15 UTP17 UTP18 UTP20 UTP25 UTP3 UTP4 UTP5 UTP6 WBSCR22 WDR12 WDR18 WDR3 WDR36 WDR43 WDR46 WDR50 WDR75 WDSOF1 XRN2 cPERP-E	Homo sapiens (human)
Biosynthesis of E-series 18(S)-resolvins	15-hydroxyprostaglandin dehydrogenase [NAD(+)] Leukotriene A-4 hydrolase Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15	P09917 P09960 P15428 P16050	ALOX15 ALOX5 HPGD LOG15 LOG5 LTA4 LTA4H PGDH1 SDR36C1	Homo sapiens (human)
FGFR2 alternative splicing	Cytotoxic granule associated RNA binding protein TIA1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Epithelial splicing regulatory protein 1 Epithelial splicing regulatory protein 2 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein M Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nucleolysin TIAR Polypyrimidine tract-binding protein 1 RNA binding protein fox-1 homolog 2	O15514 O43251 P09651 P13984 P19387 P19388 P24928 P26599 P30876 P31483 P31943 P35269 P36954 P52272 P52298 P52434 P52435 P52597 P53803 P61218 P62487 P62875 Q01085 Q09161 Q6NXG1 Q9H6T0	CBP20 CBP80 ESRP1 ESRP2 FOX2 GTF2F1 GTF2F2 HNRNPA1 HNRNPF HNRNPH1 HNRNPM HNRPA1 HNRPF HNRPH HNRPH1 HNRPM HRNBP2 NAGR1 NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PTB PTBP1 RAP30 RAP74 RBFOX2 RBM35A RBM35B RBM9 RPB7 RTA TIA1 TIAL1	Homo sapiens (human)

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