GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1576 - 1600** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
MPS IIIC - Sanfilippo syndrome C	Heparan-alpha-glucosaminide N-acetyltransferase	Q68CP4	HGSNAT TMEM76	Homo sapiens (human)
Circadian Clock	3'-5' exoribonuclease HELZ2 Basic helix-loop-helix ARNT-like protein 1 CREB-binding protein CREB-regulated transcription coactivator 1 CREB-regulated transcription coactivator 2 CREB-regulated transcription coactivator 3 Casein kinase I isoform delta Casein kinase I isoform epsilon Chromodomain-helicase-DNA-binding protein 9 Circadian locomoter output cycles protein kaput Class E basic helix-loop-helix protein 41 Cryptochrome-1 Cryptochrome-2 Cullin-1 Cyclic AMP-dependent transcription factor ATF-2 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 F-box/LRR-repeat protein 3 F-box/WD repeat-containing protein 1A Glucocorticoid receptor Histone acetyltransferase p300 Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Hypoxia-inducible factor 1-alpha Mediator of RNA polymerase II transcription subunit 1 Myocyte-specific enhancer factor 2C Myocyte-specific enhancer factor 2D NAD-dependent protein deacetylase sirtuin-1 Neuronal PAS domain-containing protein 2 Nuclear factor interleukin-3-regulated protein Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor-interacting protein 1 Period circadian protein homolog 1 Period circadian protein homolog 2 Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Polyubiquitin-B Polyubiquitin-C RNA-binding protein 4 Retinoic acid receptor RXR-alpha Retinoic acid-induced protein 1 S-phase kinase-associated protein 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Serine/threonine-protein kinase SIK1 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Trimethylguanosine synthase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00327 O15055 O15379 O15516 O15534 O60907 O75376 P04150 P0CG47 P0CG48 P15336 P19793 P20393 P35398 P36873 P48552 P48730 P49674 P57059 P62136 P62140 P62979 P62987 P63208 Q06413 Q07869 Q09472 Q13616 Q14686 Q14814 Q15596 Q15648 Q15788 Q16526 Q16649 Q16665 Q3L8U1 Q49AN0 Q53ET0 Q6STE5 Q6UUV7 Q6UUV9 Q7Z5J4 Q86X55 Q92793 Q96EB6 Q96RS0 Q99743 Q9BWF3 Q9BYK8 Q9BZK7 Q9C0J9 Q9UBK2 Q9UKT7 Q9Y297	AIB3 ARC205 ARNTL ATF2 BAF60C BHLHB3 BHLHE41 BHLHE5 BHLHE74 BHLHE75 BHLHE78 BHLHE8 BHLHE9 BMAL1 BTRC BTRCP CARM1 CBP CHD9 CLOCK CREB2 CREBBP CREBP1 CRSP1 CRSP200 CRTC1 CRTC2 CRTC3 CRY1 CRY2 CSNK1D CSNK1E CUL1 DEC2 DRIP205 DRIP230 E4BP4 EAR1 EMC19 EP300 FBL3A FBW1A FBXL3 FBXL3A FBXW1A GRL HCA137 HCKID HDAC3 HELZ2 HIF1A HREV IL3BP1 IRA1 KIAA0181 KIAA0308 KIAA0334 KIAA0347 KIAA0482 KIAA0616 KIAA0658 KIAA1047 KIAA1769 KIAA1820 KISH2 LEM6 MECT1 MED1 MEF2C MEF2D MOP1 MOP3 MOP4 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NFIL3 NPAS2 NR1C1 NR1D1 NR1F1 NR2B1 NR3C1 NRIP1 OCP2 P300 PASD3 PASD4 PASD8 PBP PER PER1 PER2 PGC1 PGC1A PHLL1 PIMT PPAR PPARA PPARBP PPARGBP PPARGC1 PPARGC1A PPP1A PPP1CA PPP1CB PPP1CC PRIC285 PRIC320 PRMT4 RAI1 RAP250 RB18A RBM4 RBM4A RIGUI RORA RPS27A RXRA RZRA SHARP1 SIK SIK1 SIR2L1 SIRT1 SKP1 SKP1A SMARCD3 SNF1LK SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TCEB1L TGS1 THRAL TIF2 TORC1 TORC2 TORC3 TRAP220 TRBP TRIP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WAMTP1	Homo sapiens (human)
Synthesis of 15-eicosatetraenoic acid derivatives	Glutathione peroxidase 1 Glutathione peroxidase 2 Phospholipid hydroperoxide glutathione peroxidase GPX4 Polyunsaturated fatty acid lipoxygenase ALOX15 Polyunsaturated fatty acid lipoxygenase ALOX15B Prostaglandin G/H synthase 2	O15296 P07203 P16050 P18283 P35354 P36969	ALOX15 ALOX15B COX2 GPX1 GPX2 GPX4 LOG15 PTGS2	Homo sapiens (human)
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	Enoyl-CoA hydratase, mitochondrial Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Medium-chain specific acyl-CoA dehydrogenase, mitochondrial Trifunctional enzyme subunit alpha, mitochondrial Trifunctional enzyme subunit beta, mitochondrial	P11310 P30084 P40939 P55084 Q16836	ACADM ECHS1 HAD HAD1 HADH HADHA HADHB HADHSC SCHAD	Homo sapiens (human)
LXRs regulate gene expression linked to cholesterol transport and efflux	ADP-ribosylation factor-like protein 4C ATP-binding cassette sub-family G member 1 ATP-binding cassette sub-family G member 5 ATP-binding cassette sub-family G member 8 Apolipoprotein C-I Apolipoprotein C-II Apolipoprotein C-IV Apolipoprotein D Apolipoprotein E Cholesteryl ester transfer protein Endonuclease/exonuclease/phosphatase family domain-containing protein 1 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 G protein pathway suppressor 2 Helicase MOV-10 Histone acetyltransferase p300 Histone deacetylase 3 Lysine-specific demethylase 3A Lysine-specific demethylase 4A Lysine-specific histone demethylase 1A Lysine-specific histone demethylase 2 Nuclear receptor coactivator 1 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Phospholipid-transporting ATPase ABCA1 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein	O15379 O60341 O60907 O75164 O75376 O95477 P02649 P02654 P02655 P05090 P11597 P19793 P28702 P45844 P55055 P55056 P56559 Q09472 Q13133 Q13227 Q15788 Q7L9B9 Q8NB78 Q8NDV7 Q9BZK7 Q9H221 Q9H222 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9UKV8 Q9UL18 Q9UPQ9 Q9Y4C1 Q9Y618	ABC1 ABC8 ABCA1 ABCG1 ABCG5 ABCG8 AGO1 AGO2 AGO3 AGO4 AOF1 AOF2 APC2 APOC1 APOC2 APOC4 APOD APOE ARL4C ARL7 BHLHE74 C6orf193 CAGH26 CERP CETP CTG26 EEPD1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 EP300 GPS2 HDAC3 IRA1 JHDM2A JHDM3A JMJD1 JMJD1A JMJD2 JMJD2A KDM1 KDM1A KDM1B KDM3A KDM4A KIAA0601 KIAA0677 KIAA0742 KIAA1047 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 KIAA1706 LSD1 LSD2 LXRA LXRB MOV10 NCOA1 NCOR1 NCOR2 NER NR1H2 NR1H3 NR2B1 NR2B2 P300 RXRA RXRB SRC1 TBL1 TBL1X TBL1XR1 TBLR1 TNRC6 TNRC6A TNRC6B TNRC6C TSGA UNR WHT1	Homo sapiens (human)
Telomere C-strand (Lagging Strand) Synthesis	Adrenocortical dysplasia protein homolog DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 Proliferating cell nuclear antigen Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2	P12004 P28340 P49005 P54274 Q15054 Q15554 Q96AP0 Q9BSI4 Q9HCU8 Q9NUX5 Q9NYB0	ACD DRIP5 KIAA0039 PCNA PIN2 PIP1 POLD POLD1 POLD2 POLD3 POLD4 POLDS POT1 PTOP RAP1 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2	Homo sapiens (human)
Regulation of RUNX2 expression and activity	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Bone morphogenetic protein 2 Core-binding factor subunit beta Cullin-1 E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase SMURF1 Estrogen receptor Glucocorticoid receptor Glycogen synthase kinase-3 beta Homeobox protein DLX-5 Homeobox protein DLX-6 Homeobox protein MSX-2 Homeobox protein Nkx-3.2 NEDD4-like E3 ubiquitin-protein ligase WWP1 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Peroxisome proliferator-activated receptor gamma coactivator 1-beta Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 S-phase kinase-associated protein 1 S-phase kinase-associated protein 2 Signal transducer and activator of transcription 1-alpha/beta Steroid hormone receptor ERR1 Transcription factor HIVEP3 Twist-related protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 P03372 P04150 P0CG47 P0CG48 P11474 P12643 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35548 P35998 P42224 P43686 P48556 P49720 P49721 P49841 P51665 P56178 P56179 P60896 P60900 P62191 P62195 P62333 P62877 P62979 P62987 P63208 P78367 Q13200 Q13309 Q13616 Q13951 Q15008 Q15672 Q16186 Q5T1R4 Q86YN6 Q99436 Q99460 Q9H0M0 Q9HCE7 Q9UBK2 Q9UNE7 Q9UNM6	ADRM1 BAPX1 BHLHA38 BMP2 BMP2A C7orf76 CBFB CHIP CUL1 DLX5 DLX6 DSS1 EMC19 ERR1 ESR ESR1 ESRL1 ESRRA FBXL1 GP110 GRL GSK3B HC2 HC3 HC8 HC9 HIVEP3 HOX8 HSPC KBP1 KIAA0107 KIAA1555 KIAA1625 KRC LEM6 LMPX LMPY MB1 MIP224 MOV34L MSS1 MSX2 NKX3-2 NKX3B NR3A1 NR3B1 NR3C1 NU OCP2 PERC PFAAP4 PGC1 PGC1A PGC1B POH1 PPARGC1 PPARGC1A PPARGC1B PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RBX1 RNF75 ROC1 RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SKP2 SMURF1 STAT1 STUB1 SUG1 SUG2 TBP1 TBP7 TCEB1L TRAP2 TWIST TWIST1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWP1 X Y Z ZAS3	Homo sapiens (human)
Dasatinib-resistant KIT mutants	Mast/stem cell growth factor receptor Kit	P10721	KIT SCFR	Homo sapiens (human)
Phosphorylation of Emi1	Cell division cycle protein 20 homolog Cyclin-dependent kinase 1 F-box only protein 5 Fizzy-related protein homolog G2/mitotic-specific cyclin-B1 Serine/threonine-protein kinase PLK1	P06493 P14635 P53350 Q12834 Q9UKT4 Q9UM11	CCNB CCNB1 CDC2 CDC20 CDC28A CDH1 CDK1 CDKN1 EMI1 FBX5 FBXO5 FYR FZR FZR1 KIAA1242 P34CDC2 PLK PLK1	Homo sapiens (human)
SLIT2:ROBO1 increases RHOA activity	Roundabout homolog 1 Slit homolog 2 protein Transforming protein RhoA Unconventional myosin-IXb	O94813 P61586 Q13459 Q9Y6N7	ARH12 ARHA DUTT1 MYO9B MYR5 RHO12 RHOA ROBO1 SLIL3 SLIT2	Homo sapiens (human)
Apoptosis induced DNA fragmentation	Caspase-3 DNA fragmentation factor subunit alpha DNA fragmentation factor subunit beta High mobility group protein B1 High mobility group protein B2 Histone H1.0 Histone H1.1 Histone H1.2 Histone H1.3 Histone H1.4 Histone H1.5 Importin subunit alpha-5 Importin subunit beta-1	O00273 O76075 P07305 P09429 P10412 P16401 P16402 P16403 P26583 P42574 P52294 Q02539 Q14974	CAD CASP3 CPP32 DFF1 DFF2 DFF40 DFF45 DFFA DFFB H1-0 H1-1 H1-2 H1-3 H1-4 H1-5 H1F0 H1F1 H1F2 H1F3 H1F4 H1F5 H1FV HIST1H1A HIST1H1B HIST1H1C HIST1H1D HIST1H1E HMG1 HMG2 HMGB1 HMGB2 KPNA1 KPNB1 NTF97 RCH2	Homo sapiens (human)
Interleukin-20 family signaling	Interferon lambda receptor 1 Interferon lambda-1 Interferon lambda-2 Interferon lambda-3 Interleukin-10 receptor subunit beta Interleukin-19 Interleukin-20 receptor subunit alpha Interleukin-20 receptor subunit beta Interleukin-20 Interleukin-22 receptor subunit alpha-1 Interleukin-22 receptor subunit alpha-2 Interleukin-22 Interleukin-24 Interleukin-26 Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 2 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 4 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Tyrosine-protein phosphatase non-receptor type 11	O60674 P23458 P29597 P40763 P42224 P42229 P51692 P52333 P52630 Q06124 Q08334 Q13007 Q14765 Q6UXL0 Q8IU54 Q8IU57 Q8IZI9 Q8IZJ0 Q8N6P7 Q969J5 Q9GZX6 Q9NPH9 Q9NYY1 Q9UHD0 Q9UHF4	AK155 APRF CRFB4 D21S58 D21S66 DIRS1 IFNL1 IFNL2 IFNL3 IFNLR1 IL10RB IL19 IL20 IL20RA IL20RB IL22 IL22R IL22RA1 IL22RA2 IL24 IL26 IL28A IL28B IL28C IL28RA IL29 ILTIF JAK1 JAK1A JAK1B JAK2 JAK3 LICR2 MDA7 PTP2C PTPN11 SHPTP2 ST16 STAT1 STAT2 STAT3 STAT4 STAT5 STAT5A STAT5B TYK2 ZCYTO10 ZCYTO18 ZCYTO20 ZCYTO21 ZCYTO22 ZMDA1	Homo sapiens (human)
lestaurtinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
Signaling by MAP2K mutants	Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3	P27361 P28482 P36507 Q02750	ERK1 ERK2 MAP2K1 MAP2K2 MAPK1 MAPK3 MEK1 MEK2 MKK2 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2	Homo sapiens (human)
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	Apoptotic protease-activating factor 1 Caspase-3 Caspase-7 Caspase-9 Cytochrome c Diablo IAP-binding mitochondrial protein E3 ubiquitin-protein ligase XIAP	O14727 P42574 P55210 P55211 P98170 P99999 Q9NR28	APAF1 API3 BIRC4 CASP3 CASP7 CASP9 CPP32 CYC CYCS DIABLO IAP3 KIAA0413 MCH3 MCH6 SMAC XIAP	Homo sapiens (human)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase NEDD4-like E3 ubiquitin-protein ligase SMURF1 E3 ubiquitin-protein ligase SMURF2 Exportin-1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 7 Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4 Polyubiquitin-B Polyubiquitin-C Protein TMEPAI Protein phosphatase 1 regulatory subunit 15A Serine-threonine kinase receptor-associated protein Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Serine/threonine-protein phosphatase PP1-beta catalytic subunit Serine/threonine-protein phosphatase PP1-gamma catalytic subunit TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta-1 proprotein Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase isozyme L5 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14980 O15105 O75807 P01137 P0CG47 P0CG48 P36873 P36897 P37173 P62136 P62140 P62979 P62987 P84022 Q13145 Q15796 Q969W9 Q96PU5 Q9HAU4 Q9HCE7 Q9NYA4 Q9UNE7 Q9Y3F4 Q9Y4E8 Q9Y5K5	ALK5 BAMBI CHIP CRM1 GADD34 KIAA0439 KIAA0529 KIAA0647 KIAA1625 MADH2 MADH3 MADH7 MADH8 MADR2 MAWD MTMR4 NEDD4L NEDL3 NMA PMEPA1 PPP1A PPP1CA PPP1CB PPP1CC PPP1R15A RPS27A SKR4 SMAD2 SMAD3 SMAD7 SMURF1 SMURF2 STAG1 STRAP STUB1 TGFB TGFB1 TGFBR1 TGFBR2 TMEPAI UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UCH37 UCHL5 UNRIP USP15 XPO1 ZFYVE11	Homo sapiens (human)
Cardiogenesis	Catenin beta-1 Eomesodermin homolog Forkhead box protein O4 Hairy/enhancer-of-split related with YRPW motif protein 1 Hairy/enhancer-of-split related with YRPW motif protein 2 Heart- and neural crest derivatives-expressed protein 1 Heart- and neural crest derivatives-expressed protein 2 Histone acetyltransferase KAT2A Histone acetyltransferase KAT5 Histone-lysine N-methyltransferase SMYD1 Homeobox protein Nkx-2.5 Insulin gene enhancer protein ISL-1 LIM domain-binding protein 1 Lymphoid enhancer-binding factor 1 Mesoderm posterior protein 1 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 4 Myocardin Myocyte-specific enhancer factor 2C Serum response factor T-box transcription factor T T-box transcription factor TBX1 T-box transcription factor TBX20 T-box transcription factor TBX5 Transcription factor GATA-4 Transcription factor GATA-6 WD repeat-containing protein 5	O15178 O43435 O95936 O96004 P11831 P35222 P43694 P52952 P61296 P61371 P61964 P98177 Q06413 Q13485 Q15797 Q86U70 Q8IZQ8 Q8NB12 Q92830 Q92908 Q92993 Q99593 Q9BRJ9 Q9UBP5 Q9UJU2 Q9UMR3 Q9Y5J3	AFX AFX1 BHLHA26 BHLHA27 BHLHB31 BHLHB32 BHLHC5 BIG3 BSP1 CHF1 CHF2 CLIM2 CSX CTNNB CTNNB1 DHAND DPC4 EHAND EOMES FOXO4 GATA4 GATA6 GCN5 GCN5L2 GRL HAND1 HAND2 HERP HERP1 HERP2 HESR1 HEY1 HEY2 HRT1 HRT2 HTATIP ISL1 KAT2A KAT5 LDB1 LEF1 MADH1 MADH4 MADR1 MEF2C MESP1 MLLT7 MYCD MYOCD NKX2-5 NKX2.5 NKX2E SMAD1 SMAD4 SMYD1 SRF T TBR2 TBX1 TBX20 TBX5 TBXT TIP60 WDR5	Homo sapiens (human)
Regulation of IFNA/IFNB signaling	Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon alpha/beta receptor 1 Interferon beta Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 2 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein phosphatase non-receptor type 11 Tyrosine-protein phosphatase non-receptor type 1 Tyrosine-protein phosphatase non-receptor type 6 Ubl carboxyl-terminal hydrolase 18	O14543 O15524 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P17181 P18031 P23458 P29350 P29597 P32881 P52630 Q06124 Q9UMW8	CIS3 HCP IFB IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR IFNAR1 IFNB IFNB1 ISG43 JAK1 JAK1A JAK1B PTP1B PTP1C PTP2C PTPN1 PTPN11 PTPN6 SHPTP2 SOCS1 SOCS3 SSI1 SSI3 STAT2 TIP3 TYK2 USP18	Homo sapiens (human)
Amyloid fiber formation	ADP-ribosylation factor-binding protein GGA1 ADP-ribosylation factor-binding protein GGA2 ADP-ribosylation factor-binding protein GGA3 Alpha-synuclein Amyloid-beta precursor protein Apolipoprotein A-I Apolipoprotein A-IV Apolipoprotein E Basement membrane-specific heparan sulfate proteoglycan core protein Beta-2-microglobulin Beta-secretase 1 Calbindin Calcitonin Cystatin-C Disintegrin and metalloproteinase domain-containing protein 10 E3 ubiquitin-protein ligase SIAH1 E3 ubiquitin-protein ligase SIAH2 E3 ubiquitin-protein ligase parkin Fibrinogen alpha chain Furin Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Gelsolin Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.Z Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1 Histone H3.2 Histone H3.3 Histone H4 Insulin Integral membrane protein 2B Islet amyloid polypeptide Lactadherin Lactotransferrin Lysozyme C N-acetyltransferase 8 Natriuretic peptides A Nicastrin Odontogenic ameloblast-associated protein Polyubiquitin-B Polyubiquitin-C Prolactin Putative N-acetyltransferase 8B Semenogelin-1 Serum amyloid A-1 protein Serum amyloid P-component Sortilin-related receptor Synphilin-1 Tetraspanin-14 Tetraspanin-15 Tetraspanin-33 Tetraspanin-5 Transforming growth factor-beta-induced protein ig-h3 Transthyretin Ubiquitin carboxyl-terminal hydrolase 9X Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6	A1E959 O14672 O14933 O43255 O60260 O60814 O95858 P01034 P01160 P01236 P01258 P01308 P02647 P02649 P02671 P02743 P02766 P02788 P04279 P04908 P05067 P05937 P06396 P06727 P06899 P09958 P0C0S5 P0C5Y9 P0CG47 P0CG48 P0DJI8 P10997 P16104 P20671 P23527 P33778 P37840 P56817 P57053 P58876 P61626 P61769 P62079 P62805 P62807 P62979 P62987 P68431 P84243 P98160 Q08431 Q15582 Q16777 Q16778 Q6FI13 Q71DI3 Q86UF1 Q8IUQ4 Q8N257 Q8NG11 Q8WW43 Q92542 Q92673 Q93008 Q93077 Q93079 Q96A08 Q96BI3 Q99877 Q99878 Q99879 Q99880 Q9NZ42 Q9NZ52 Q9UHE5 Q9UHF3 Q9UJY4 Q9UJY5 Q9Y287 Q9Y6H5	A4 AD1 ADAM10 ANP APCS APH1A APH1B APIN APOA1 APOA4 APOE APP B2M BACE BACE1 BIGH3 BRI BRI2 C11orf32 CAB27 CALB1 CALC1 CALCA CML1 CML2 CST3 DFFRX FAM FGA FUR FURIN GGA1 GGA2 GGA3 GIG12 GLA GSN H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFL H2AFM H2AFO H2AFQ H2AFX H2AFZ H2AX H2AZ H2AZ1 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3.3A H3.3B H3C1 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 H3F2 H3F3 H3F3A H3F3B H3FA H3FB H3FC HIST1H3C H3FD H3FF H3FH H3FI H3FJ H3FK H3FL H3FM H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H3A HIST2H3C HIST2H3D HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HSPG2 HUMSIAH IAPP INS ITM2B KIAA0154 KIAA0253 KIAA1080 KIAA1149 KUZ LF LTF LYZ LZM MADM MFGE8 NACP NAT8 NAT8B NCSTN NET7 NPPA ODAM PACE PALB PARK1 PARK2 PCSK3 PEN PEN2 PND PRKN PRL PSENEN PSF PSFL PTX2 RPS27A SAA1 SEMG SEMG1 SIAH1 SIAH2 SNCA SNCAIP SORL1 TGFBI TM4SF14 TM4SF15 TM4SF9 TSC501 TSH2B TSPAN14 TSPAN15 TSPAN33 TSPAN5 TTR UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH8 UBE2L6 USP9 USP9X	Homo sapiens (human)
Sema3A PAK dependent Axon repulsion	Cofilin-1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1 Plexin-A1 Plexin-A2 Plexin-A3 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fes/Fps Tyrosine-protein kinase Fyn	O14786 O75051 O75914 P06241 P07332 P07900 P08238 P23528 P51805 P53667 P63000 Q13153 Q13177 Q14563 Q9HCM2 Q9UIW2	CFL CFL1 FES FPS FYN HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB KIAA0463 KIAA1550 LIMK LIMK1 NOV NRP NRP1 OCT OPHN3 PAK1 PAK2 PAK3 PLXN1 PLXN2 PLXN4 PLXNA1 PLXNA2 PLXNA3 PLXNA4 PLXNA4A PLXNA4B RAC1 SEMA3A SEMAD SEX TC25 VEGF165R	Homo sapiens (human)
Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence	DNA ligase 1 Telomerase reverse transcriptase	O14746 P18858	EST2 LIG1 TCS1 TERT TRT	Homo sapiens (human)
Activated NTRK2 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Neurotrophin-4	P19174 P23560 P34130 Q16620	BDNF NTF4 NTF5 NTRK2 PLC1 PLCG1 TRKB	Homo sapiens (human)
Synthesis of PIPs in the nucleus	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase	P48426 P78356 Q86T03 Q8TBX8	C14orf9 PI5P4KA PIP4K2A PIP4K2B PIP4K2C PIP4P1 PIP5K2 PIP5K2A PIP5K2B PIP5K2C TMEM55B	Homo sapiens (human)
Regulation of TP53 Activity through Association with Co-factors	Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 Cellular tumor antigen p53 PHD finger protein 20 POU domain, class 4, transcription factor 1 POU domain, class 4, transcription factor 2 Protein BANP RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase RelA-associated inhibitor Tumor protein 63 Tumor protein p73 Zinc finger protein 385A	O15350 P04637 P31749 P31751 Q01851 Q12837 Q13625 Q8N9N5 Q8WUF5 Q96KQ4 Q96PM9 Q9BVI0 Q9H3D4 Q9Y243	AKT1 AKT2 AKT3 ASPP1 ASPP2 BANP BBP BEND1 BRN3A BRN3B C20orf104 GLEA2 HCA58 HZF IASPP KET KIAA0771 NKIP1 NZF P53 P63 P73 P73H P73L PHF20 PKB PKBG POU4F1 POU4F2 PPP1R13B PPP1R13BL PPP1R13L RAC RAI RDC1 RZF SMAR1 TP53 TP53BP2 TP63 TP73 TP73L TZP ZNF385 ZNF385A	Homo sapiens (human)
Ligand-independent caspase activation via DCC	Caspase-3 Caspase-9 DCC-interacting protein 13-alpha Death-associated protein kinase 1 Death-associated protein kinase 2 Death-associated protein kinase 3 Melanoma-associated antigen D1 Netrin receptor DCC Netrin receptor UNC5A Netrin receptor UNC5B	O43293 P42574 P43146 P53355 P55211 Q6ZN44 Q8IZJ1 Q9UIK4 Q9UKG1 Q9Y5V3	APPL APPL1 CASP3 CASP9 CPP32 DAPK DAPK1 DAPK2 DAPK3 DCC DIP13A IGDCC1 KIAA1428 KIAA1976 MAGED1 MCH6 NRAGE P53RDL1 UNC5A UNC5B UNC5H1 UNC5H2 ZIPK	Homo sapiens (human)

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