GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **2051 - 2075** of **2090** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	GlyTouCan ID
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	O14944 P00533 P01133 P01135 P15514 P19174 P35070 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 PLC1 PLCG1 SDGF TGFA
ISG15 antiviral mechanism	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Aladin Antiviral innate immune response receptor RIG-I Beclin-1 E3 ISG15--protein ligase HERC5 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase ARIH1 E3 ubiquitin-protein ligase NEDD4 E3 ubiquitin/ISG15 ligase TRIM25 Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic initiation factor 4A-III Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4 gamma 2 Eukaryotic translation initiation factor 4 gamma 3 Eukaryotic translation initiation factor 4E type 2 Eukaryotic translation initiation factor 4E type 3 Eukaryotic translation initiation factor 4E Filamin-B Gag polyprotein Importin subunit alpha-1 Importin subunit alpha-3 Importin subunit alpha-4 Importin subunit alpha-5 Importin subunit alpha-6 Importin subunit alpha-8 Importin subunit beta-1 Interferon regulatory factor 3 Interferon-induced GTP-binding protein Mx1 Interferon-induced GTP-binding protein Mx2 Interferon-induced protein with tetratricopeptide repeats 1 Interferon-induced, double-stranded RNA-activated protein kinase Mitogen-activated protein kinase 3 Non-structural protein 1 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Polyubiquitin-B Polyubiquitin-C Protein SEC13 homolog Protein phosphatase 1B Signal transducer and activator of transcription 1-alpha/beta Tyrosine-protein kinase JAK1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 N Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ISG15 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Ubiquitin/ISG15-conjugating enzyme E2 L6 Ubl carboxyl-terminal hydrolase 18 mRNA export factor RAE1	A8CG34 A9QM74 O00505 O00629 O14933 O15131 O15504 O43432 O60573 O75369 O75688 O75694 O95786 P03496 P05161 P06730 P09914 P0CG47 P0CG48 P12270 P12493 P19174 P19525 P20591 P20592 P23458 P27361 P35658 P37198 P38919 P41226 P42224 P46934 P49790 P49792 P51965 P52292 P52294 P55735 P57740 P60842 P61088 P62979 P62987 P78344 P78406 Q04637 Q12769 Q13526 Q14240 Q14258 Q14457 Q14653 Q14974 Q5SRE5 Q7Z3B4 Q8N1F7 Q8N5X7 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUM0 Q92621 Q96HA1 Q99567 Q9BTX1 Q9BW27 Q9NRG9 Q9UII4 Q9UKX7 Q9UMW8 Q9Y4X5	AAAS ADRACALA ARI ARIH1 BECN1 BLU C7orf14 CAIN CAN CEB1 CEBP1 CG1 D3S1231E DAP5 DDX2A DDX2B DDX48 DDX58 EFP EIF2AK2 EIF4A EIF4A1 EIF4A2 EIF4A3 EIF4E EIF4E2 EIF4E3 EIF4EL1 EIF4EL3 EIF4F EIF4G EIF4G1 EIF4G2 EIF4G3 EIF4GI ERK1 FLN1L FLN3 FLNB G10P1 G1P2 GT197 HERC5 IFI56 IFIT1 IFNAI1 IRF3 ISG15 ISG43 ISG56 JAK1 JAK1A JAK1B KIAA0023 KIAA0093 KIAA0095 KIAA0111 KIAA0169 KIAA0197 KIAA0225 KIAA0618 KIAA0791 KIAA0906 KPNA1 KPNA2 KPNA3 KPNA4 KPNA5 KPNA7 KPNB1 MAPK3 MOP6 MP44 MRNP41 MX1 MX2 NDC1 NEDD4 NEDD4-1 NPAP60L NS NTF97 NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 PCNT1 PIN1 PKR PLC1 PLCG1 POM121 POM121A POM121C PP2CB PPM1B PRKM3 PRKR QIP1 QIP2 RAE1 RANBP2 RCH1 RCH2 RIGI RNF147 RPF1 RPS27A SEC13 SEC13A SEC13L1 SEC13R SRP1 STAT1 TABP TAP TMEM48 TPR TRIM25 UBA52 UBA7 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH6 UBCH7BP UBCH8 UBE1L UBE2 UBE2E1 UBE2L6 UBE2N UCRP USP18 ZNF147 gag
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Adapter molecule crk Breast cancer anti-estrogen resistance protein 1 Crk-like protein Cytoplasmic protein NCK2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Proto-oncogene tyrosine-protein kinase Src Rap guanine nucleotide exchange factor 1 Ras GTPase-activating protein 1 SH2/SH3 adapter protein NCK1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription 5B Signal transducer and activator of transcription 6 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O00459 O43639 P01111 P01112 P01127 P09619 P12931 P16234 P16333 P19174 P20936 P27986 P40763 P42224 P42226 P42229 P42336 P42338 P46108 P46109 P51692 P56945 Q06124 Q07889 Q13905 Q14451	APRF BCAR1 CAS CASS1 CRK CRKAS CRKL GAP GRB1 GRB4 GRB7 GRF2 HRAS HRAS1 NCK NCK1 NCK2 NRAS PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTP2C PTPN11 RAPGEF1 RASA RASA1 RHEPDGFRA SHPTP2 SIS SOS1 SRC SRC1 STAT1 STAT3 STAT5 STAT5A STAT5B STAT6
Signaling by ALK fusions and activated point mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK tyrosine kinase receptor B-cell lymphoma/leukemia 11A Baculoviral IAP repeat-containing protein 6 Bifunctional purine biosynthesis protein ATIC Cellular tumor antigen p53 Clathrin heavy chain 1 Cyclin-dependent kinase inhibitor 1 Cysteine--tRNA ligase, cytoplasmic Dynactin subunit 1 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase RNF213 Echinoderm microtubule-associated protein-like 4 Elongation factor 1-gamma Eukaryotic translation initiation factor 2-alpha kinase 3 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibronectin GRIP and coiled-coil domain-containing protein 2 Growth factor receptor-bound protein 2 Huntingtin-interacting protein 1 Induced myeloid leukemia cell differentiation protein Mcl-1 Insulin receptor substrate 1 Interleukin-10 Interleukin-22 Kinesin light chain 1 Kinesin-1 heavy chain LIM domain only protein 7 Liprin-beta-1 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Moesin Myosin-9 Non-receptor tyrosine-protein kinase TYK2 Nucleophosmin Nucleoprotein TPR Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Polyubiquitin-B Polyubiquitin-C Protein TFG Protein phosphatase 1B Protein transport protein Sec31A Ribosome-binding protein 1 Sequestosome-1 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Striatin Transcription factor Jun Tropomyosin alpha-3 chain Tropomyosin alpha-4 chain Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Vinculin WD repeat and coiled-coil-containing protein cAMP-dependent protein kinase type I-alpha regulatory subunit	O00291 O00459 O43559 O43815 O75688 O94979 P02751 P04637 P05412 P06748 P06753 P0CG47 P0CG48 P10644 P12270 P18206 P19174 P22301 P26038 P26641 P27986 P29597 P31939 P33176 P35568 P35579 P38936 P40763 P42224 P42336 P42338 P45983 P45984 P49589 P49792 P62979 P62987 P62993 P67936 Q00610 Q00987 Q07820 Q07866 Q13501 Q14203 Q63HN8 Q86W92 Q8IWJ2 Q8WU20 Q8WWI1 Q92734 Q9GZX6 Q9H165 Q9H6R7 Q9HC35 Q9NR09 Q9NZJ5 Q9P2E9 Q9UM73	ALK ALO17 APRF ASH ATIC BCL11A BCL2L3 BIRC6 C17orf27 C2orf2 C2orf44 CAP20 CARS CARS1 CDKN1 CDKN1A CIP1 CLH17 CLTC CLTCL2 CTIP1 DCTN1 EEF1G EF1G EIF2AK3 EMAPL4 EML4 EVI9 FBX20 FBXO20 FN FN1 FRS2 FRS3 GCC2 GRB1 GRB2 HIP1 IL10 IL22 ILTIF IRS1 JNK1 JNK2 JUN KIAA0034 KIAA0336 KIAA0858 KIAA0905 KIAA1230 KIAA1289 KIAA1398 KIAA1554 KIAA1618 KIAA1809 KIF5B KLC KLC1 KNS KNS1 KNS2 LMO7 MAPK8 MAPK9 MCL1 MDA6 MDM2 MSN MYH9 MYSTR NPM NPM1 NUP358 ORCA OSIL P53 PEK PERK PIC1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PKR1 PLC1 PLCG1 PP2CB PPFIBP1 PPM1B PRKAR1 PRKAR1A PRKM8 PRKM9 PURH RANBP2 RANBP2L4 RNF213 RPS27A RRBP1 SAPK1 SAPK1A SAPK1C SDI1 SEC31A SEC31L1 SQSTM1 STAT1 STAT3 STRN TFG TP53 TPM3 TPM4 TPR TSE1 TYK2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCL WAF1 WDCP ZCYTO18 ZNF856
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 ALK and LTK ligand 1 ALK and LTK ligand 2 ALK tyrosine kinase receptor Fibroblast growth factor receptor substrate 2 Insulin receptor substrate 1 Midkine Myc proto-oncogene protein N-myc proto-oncogene protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Pleiotrophin Signal transducer and activator of transcription 3 Tyrosine-protein kinase JAK3 Tyrosine-protein phosphatase non-receptor type 6	O00459 P01106 P04198 P19174 P21246 P21741 P27986 P29350 P35568 P40763 P42336 P42338 P52333 Q6UX46 Q6UXT8 Q8WU20 Q9UM73	ALK ALKAL1 ALKAL2 APRF BHLHE37 BHLHE39 FAM150A FAM150B FRS2 GRB1 HBNF1 HCP IRS1 JAK3 MDK MK1 MYC MYCN NEGF1 NEGF2 NMYC PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PTN PTP1C PTPN6 STAT3
VEGFR2 mediated cell proliferation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 3-phosphoinositide-dependent protein kinase 1 Calmodulin-1 GTPase HRas GTPase NRas Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C zeta type Ras GTPase-activating protein 1 S-adenosylhomocysteine hydrolase-like protein 1 Sphingosine kinase 1 Vascular endothelial growth factor receptor 2	O15530 O43865 P01111 P01112 P05771 P0DP23 P17252 P19174 P20936 P35968 Q05513 Q05655 Q14571 Q14573 Q14643 Q9NYA1	AHCYL1 CALM CALM1 CAM CAM1 DCAL FLK1 GAP HRAS HRAS1 INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KDR NRAS PDK1 PDPK1 PKC2 PKCA PKCB PKCD PLC1 PLCG1 PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCZ RASA RASA1 SK1 SPHK SPHK1 SPK VEGFR2 XPVKONA
Erythropoietin activates Phospholipase C gamma (PLCG)	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Erythropoietin receptor Erythropoietin Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Lyn	O60674 P01588 P07948 P16885 P19174 P19235 Q9Y4H2	EPO EPOR IRS2 JAK2 JTK8 LYN PLC1 PLCG1 PLCG2
FCERI mediated MAPK activation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Dual specificity mitogen-activated protein kinase kinase 4 Dual specificity mitogen-activated protein kinase kinase 7 GRB2-related adapter protein 2 GTPase HRas GTPase NRas Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Lymphocyte cytosolic protein 2 Mitogen-activated protein kinase 10 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 Mitogen-activated protein kinase kinase kinase 1 Protein c-Fos Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Son of sevenless homolog 1 Transcription factor Jun Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O14733 O75791 P01100 P01111 P01112 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P05412 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P15498 P16885 P19174 P23083 P27361 P28482 P43405 P45983 P45984 P45985 P52735 P53779 P63000 P80748 Q07889 Q13094 Q13153 Q13177 Q13233 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9UKW4	ERK1 ERK2 FOS G0S7 GADS GRAP2 GRB2L GRID HRAS HRAS1 IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 JNK1 JNK2 JNK3 JNK3A JNKK1 JNKK2 JTK8 JUN LCP2 LYN MAP2K4 MAP2K7 MAP3K1 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MAPKKK1 MEK4 MEK7 MEKK MEKK1 MKK4 MKK7 NRAS PAK1 PAK2 PLC1 PLCG1 PLCG2 PRKM1 PRKM10 PRKM2 PRKM3 PRKM8 PRKM9 PRKMK4 PRKMK7 RAC1 SAPK1 SAPK1A SAPK1B SAPK1C SEK1 SERK1 SKK1 SKK4 SOS1 SYK TC25 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3
FCERI mediated Ca+2 mobilization	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Calcineurin subunit B type 1 Calmodulin-1 GRB2-related adapter protein 2 Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 IGHV7-81 protein Immunoglobulin heavy constant epsilon Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Lymphocyte cytosolic protein 2 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 2 Nuclear factor of activated T-cells, cytoplasmic 3 Protein phosphatase 3 catalytic subunit alpha Proto-oncogene vav S-adenosylhomocysteine hydrolase-like protein 1 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform Son of sevenless homolog 1 Tyrosine-protein kinase BTK Tyrosine-protein kinase ITK/TSK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase TXK Tyrosine-protein kinase Tec UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O43865 O75791 O95644 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01854 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P07948 P0CF74 P0CG04 P0DOY2 P0DOY3 P0DP23 P15498 P16298 P16885 P19174 P23083 P42680 P42681 P43405 P52735 P63098 P80748 Q06187 Q07889 Q08209 Q08881 Q12968 Q13094 Q13469 Q14571 Q14573 Q14643 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q9UKW4	AGMX1 AHCYL1 ATK BPK BTK CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CNA CNA2 CNB DCAL EMT GADS GRAP2 GRB2L GRID IGHE IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 INSP3R1 IRBIT ITK ITPR1 ITPR2 ITPR3 JTK8 LCP2 LYK LYN NFAT1 NFAT2 NFAT4 NFATC NFATC1 NFATC2 NFATC3 NFATP PLC1 PLCG1 PLCG2 PPP3CA PPP3CB PPP3R1 PSCTK4 PTK4 RLK SOS1 SYK TEC TXK V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 VAV VAV1 VAV2 VAV3 XPVKONA
DAP12 signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Beta-2-microglobulin GRB2-related adapter protein 2 GTPase HRas GTPase NRas Guanine nucleotide exchange factor VAV2 Guanine nucleotide exchange factor VAV3 HLA class I histocompatibility antigen, alpha chain E Lymphocyte cytosolic protein 2 NKG2-C type II integral membrane protein NKG2-D type II integral membrane protein Natural killer cells antigen CD94 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Ras-related C3 botulinum toxin substrate 1 Son of sevenless homolog 1 TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 2 Tyrosine-protein kinase BTK Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein kinase SYK	O00459 O43914 O75791 P01111 P01112 P06239 P06241 P13747 P16885 P19174 P26717 P26718 P27986 P42336 P42338 P43405 P52735 P61769 P63000 Q06187 Q07889 Q13094 Q13241 Q9NZC2 Q9UKW4	AGMX1 ATK B2M BPK BTK CD94 D12S2489E DAP12 FYN GADS GRAP2 GRB1 GRB2L GRID HLA-6.2 HLA-E HLAE HRAS HRAS1 KARAP KLRC2 KLRD1 KLRK1 LCK LCP2 NKG2C NKG2D NRAS PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PLC1 PLCG1 PLCG2 RAC1 SOS1 SYK TC25 TREM2 TYROBP VAV2 VAV3
FCGR3A-mediated IL10 synthesis	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Calmodulin-1 High affinity immunoglobulin gamma Fc receptor I IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Interleukin-10 Low affinity immunoglobulin gamma Fc region receptor II-a Low affinity immunoglobulin gamma Fc region receptor III-A Putative GIPL galf transferase S-adenosylhomocysteine hydrolase-like protein 1 T-cell surface glycoprotein CD3 gamma chain Tyrosine-protein kinase Fgr Tyrosine-protein kinase Fyn Tyrosine-protein kinase HCK Tyrosine-protein kinase Lyn Tyrosine-protein kinase SYK Tyrosine-protein kinase Yes UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment) cAMP-dependent protein kinase catalytic subunit PRKX cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O43306 O43865 O60266 O60503 O95622 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P04211 P04430 P04432 P04433 P06241 P06310 P06312 P06315 P06331 P07947 P07948 P08631 P08637 P09693 P09769 P0CF74 P0CG04 P0DOY2 P0DOY3 P0DP23 P10644 P12314 P12318 P13861 P16885 P17612 P19174 P22301 P22612 P22694 P23083 P31321 P31323 P40145 P43405 P51817 P51828 P80748 Q08462 Q08828 Q14571 Q14573 Q14643 Q4QD44 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q6PIL0 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 AHCYL1 CALM CALM1 CAM CAM1 CD16A CD32 CD3G DCAL FCG1 FCG2 FCG3 FCGR1 FCGR1A FCGR2A FCGR2A1 FCGR3 FCGR3A FGR FYN HCK IGFR1 IGFR2 IGFR3 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 IL10 INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 JTK8 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 LPG1G LPG1G2 LYN PKACA PKR1 PKR2 PKX1 PLC1 PLCG1 PLCG2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PRKX SRC2 SYK T3G TSE1 V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 XPVKONA YES YES1
Generation of second messenger molecules	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Actin nucleation-promoting factor WAS Ena/VASP-like protein FYN-binding protein 1 GRB2-related adapter protein 2 HLA class II histocompatibility antigen, DP alpha 1 chain HLA class II histocompatibility antigen, DP beta 1 chain HLA class II histocompatibility antigen, DQ alpha 1 chain HLA class II histocompatibility antigen, DQ alpha 2 chain HLA class II histocompatibility antigen, DQ beta 1 chain HLA class II histocompatibility antigen, DQ beta 2 chain HLA class II histocompatibility antigen, DR alpha chain HLA class II histocompatibility antigen, DR beta 3 chain HLA class II histocompatibility antigen, DR beta 4 chain HLA class II histocompatibility antigen, DR beta 5 chain HLA class II histocompatibility antigen, DRB1 beta chain Immunoglobulin superfamily member 2 Linker for activation of T-cells family member 1 Lymphocyte cytosolic protein 2 Protein enabled homolog SH2/SH3 adapter protein NCK1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 T cell receptor alpha chain constant T cell receptor alpha variable 19 T cell receptor alpha variable 29/delta variable 5 T cell receptor alpha variable 8-4 T cell receptor beta constant 1 T cell receptor beta variable 12-3 T cell receptor beta variable 7-9 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase ITK/TSK Tyrosine-protein kinase Lck Tyrosine-protein kinase ZAP-70 Vasodilator-stimulated phosphoprotein	A0A0A6YYK7 O15117 O43561 O75791 O75914 P01730 P01733 P01737 P01848 P01850 P01903 P01906 P01909 P01911 P01920 P04234 P04435 P04437 P04440 P05538 P06239 P07766 P09693 P13762 P16333 P16885 P19174 P20036 P42768 P43403 P50552 P79483 Q08881 Q13094 Q13153 Q13177 Q30154 Q8N8S7 Q93033 Q9UI08	CD101 CD3D CD3E CD3G CD4 EMT ENAH EVL EWI101 FYB FYB1 GADS GRAP2 GRB2L GRID HLA-DP1A HLA-DP1B HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRA1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-DXA HLA-DXB HLASB IGSF2 IMD2 ITK LAT LCK LCP2 LYK MENA NCK NCK1 OPHN3 PAK1 PAK2 PAK3 PLC1 PLCG1 PLCG2 RNB6 SLAP130 SRK T3D T3E T3G TCRA TCRBV12S3 TCRBV8S1 TRAC TRAV19 TRAV29DV5 TRAV8-4 TRBC1 TRBV12-3 TRBV7-9 V7 VASP WAS ZAP70
Role of phospholipids in phagocytosis	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 5'-3' exonuclease PLD3 5'-3' exonuclease PLD4 85/88 kDa calcium-independent phospholipase A2 High affinity immunoglobulin gamma Fc receptor I IGHV7-81 protein Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 2 Immunoglobulin heavy constant gamma 3 Immunoglobulin heavy constant gamma 4 Immunoglobulin heavy variable 1-2 Immunoglobulin heavy variable 1-46 Immunoglobulin heavy variable 1-69 Immunoglobulin heavy variable 2-5 Immunoglobulin heavy variable 2-70 Immunoglobulin heavy variable 3-11 Immunoglobulin heavy variable 3-13 Immunoglobulin heavy variable 3-23 Immunoglobulin heavy variable 3-30 Immunoglobulin heavy variable 3-33 Immunoglobulin heavy variable 3-48 Immunoglobulin heavy variable 3-53 Immunoglobulin heavy variable 3-7 Immunoglobulin heavy variable 3-9 Immunoglobulin heavy variable 4-34 Immunoglobulin heavy variable 4-39 Immunoglobulin heavy variable 4-59 Immunoglobulin kappa constant Immunoglobulin kappa variable 1-12 Immunoglobulin kappa variable 1-16 Immunoglobulin kappa variable 1-17 Immunoglobulin kappa variable 1-33 Immunoglobulin kappa variable 1-39 Immunoglobulin kappa variable 1-5 Immunoglobulin kappa variable 1D-12 Immunoglobulin kappa variable 1D-16 Immunoglobulin kappa variable 1D-33 Immunoglobulin kappa variable 1D-39 Immunoglobulin kappa variable 2-28 Immunoglobulin kappa variable 2-29 Immunoglobulin kappa variable 2-30 Immunoglobulin kappa variable 2D-28 Immunoglobulin kappa variable 2D-30 Immunoglobulin kappa variable 2D-40 Immunoglobulin kappa variable 3-11 Immunoglobulin kappa variable 3-15 Immunoglobulin kappa variable 3-20 Immunoglobulin kappa variable 3D-20 Immunoglobulin kappa variable 4-1 Immunoglobulin kappa variable 5-2 Immunoglobulin lambda constant 1 Immunoglobulin lambda constant 2 Immunoglobulin lambda constant 3 Immunoglobulin lambda constant 6 Immunoglobulin lambda constant 7 Immunoglobulin lambda variable 1-40 Immunoglobulin lambda variable 1-44 Immunoglobulin lambda variable 1-47 Immunoglobulin lambda variable 1-51 Immunoglobulin lambda variable 2-11 Immunoglobulin lambda variable 2-14 Immunoglobulin lambda variable 2-23 Immunoglobulin lambda variable 2-8 Immunoglobulin lambda variable 3-19 Immunoglobulin lambda variable 3-1 Immunoglobulin lambda variable 3-21 Immunoglobulin lambda variable 3-25 Immunoglobulin lambda variable 3-27 Immunoglobulin lambda variable 6-57 Immunoglobulin lambda variable 7-43 Immunolglobulin kappa light chain variable region L22 (Fragment) Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Low affinity immunoglobulin gamma Fc region receptor II-a Low affinity immunoglobulin gamma Fc region receptor III-A Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phospholipase D1 Phospholipase D2 Phospholipid phosphatase 4 Phospholipid phosphatase 5 Protein kinase C delta type Protein kinase C epsilon type S-adenosylhomocysteine hydrolase-like protein 1 T-cell surface glycoprotein CD3 gamma chain Tyrosine-protein kinase SYK UGa8H (Fragment) V1-11 protein (Fragment) V1-13 protein (Fragment) V1-16 protein (Fragment) V1-20 protein (Fragment) V1-3 protein (Fragment) V1-5 protein (Fragment) V1-7 protein (Fragment) V1-9 protein (Fragment) V2-11 protein (Fragment) V2-15 protein (Fragment) V2-17 protein (Fragment) V2-19 protein (Fragment) V2-8 protein (Fragment) V3-2 protein (Fragment) V3-3 protein (Fragment) V3-4 protein (Fragment) V4-1 protein (Fragment) V4-2 protein (Fragment) V4-6 protein (Fragment) V5-1 protein (Fragment) V5-4 protein (Fragment) V5-6 protein (Fragment)	A0A075B6P5 A0A075B6S6 A0A0C4DH25 A0A0C4DH73 A0M8Q6 A2KUC3 A2NJV5 A2NXD2 O00459 O14939 O43865 O60733 P01593 P01594 P01597 P01599 P01601 P01602 P01611 P01614 P01615 P01619 P01624 P01699 P01700 P01701 P01703 P01704 P01705 P01706 P01709 P01714 P01715 P01717 P01718 P01721 P01742 P01743 P01762 P01763 P01764 P01766 P01767 P01768 P01772 P01780 P01782 P01814 P01817 P01824 P01825 P01834 P01857 P01859 P01860 P01861 P04211 P04430 P04432 P04433 P06310 P06312 P06315 P06331 P08637 P09693 P0CF74 P0CG04 P0DOY2 P0DOY3 P12314 P12318 P16885 P19174 P23083 P27986 P42336 P42338 P43405 P80748 Q02156 Q05655 Q13393 Q14571 Q14573 Q14643 Q5NV61 Q5NV62 Q5NV64 Q5NV65 Q5NV66 Q5NV67 Q5NV68 Q5NV69 Q5NV75 Q5NV79 Q5NV80 Q5NV81 Q5NV82 Q5NV83 Q5NV84 Q5NV85 Q5NV86 Q5NV87 Q5NV89 Q5NV90 Q5NV91 Q5NV92 Q5VZY2 Q6PIL0 Q8IV08 Q8NEB5 Q96BZ4	AHCYL1 C14orf175 CD16A CD32 CD3G DCAL DPPL1 DPPL2 FCG1 FCG2 FCG3 FCGR1 FCGR1A FCGR2A FCGR2A1 FCGR3 FCGR3A GRB1 HTPAP IGFR1 IGFR2 IGFR3 IGHG1 IGHG2 IGHG3 IGHG4 IGHV IGHV1-2 IGHV1-46 IGHV1-69 IGHV2-5 IGHV2-70 IGHV3-11 IGHV3-13 IGHV3-23 IGHV3-30 IGHV3-33 IGHV3-48 IGHV3-53 IGHV3-7 IGHV3-9 IGHV4-34 IGHV4-39 IGHV4-59 IGHV7-81 IGKC IGKV1-12 IGKV1-16 IGKV1-17 IGKV1-33 IGKV1-39 IGKV1-5 IGKV1D-12 IGKV1D-16 IGKV1D-33 IGKV1D-39 IGKV2-28 IGKV2-29 IGKV2-30 IGKV2D-28 IGKV2D-30 IGKV2D-40 IGKV3-11 IGKV3-15 IGKV3-20 IGKV3D-20 IGKV4-1 IGKV5-2 IGLC1 IGLC2 IGLC3 IGLC6 IGLC7 IGLV IGLV1-40 IGLV1-44 IGLV1-47 IGLV1-51 IGLV2-11 IGLV2-14 IGLV2-23 IGLV2-8 IGLV3-1 IGLV3-19 IGLV3-21 IGLV3-25 IGLV3-27 IGLV6-57 IGLV7-43 INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PKCD PKCE PLA2G6 PLC1 PLCG1 PLCG2 PLD1 PLD2 PLD3 PLD4 PLPLA9 PLPP4 PLPP5 PPAPDC1 PPAPDC1A PPAPDC1B PRKCD PRKCE SYK T3G V1-11 V1-13 V1-16 V1-20 V1-3 V1-5 V1-7 V1-9 V2-11 V2-15 V2-17 V2-19 V2-8 V3-2 V3-3 V3-4 V4-1 V4-2 V4-6 V5-1 V5-4 V5-6 XPVKONA
Sensory perception of sweet, bitter, and umami (glutamate) taste	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 Calcium homeostasis modulator protein 1 Calcium homeostasis modulator protein 3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Inositol 1,4,5-trisphosphate receptor type 3 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 4 Sodium channel protein type 2 subunit alpha Sodium channel protein type 3 subunit alpha Sodium channel protein type 9 subunit alpha Sodium channel subunit beta-1 Sodium channel subunit beta-2 Sodium channel subunit beta-4 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 43 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Transient receptor potential cation channel subfamily M member 4 Transient receptor potential cation channel subfamily M member 5	A8MTJ3 O60939 P16520 P59533 P59534 P59535 P59536 P59537 P59538 P59540 P59541 P59543 P59544 P62873 Q00722 Q07699 Q13255 Q14573 Q14833 Q15858 Q7RTX0 Q7RTX1 Q86XJ0 Q8IU99 Q8IWT1 Q8TD43 Q8TE23 Q99250 Q9NY46 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9NZQ8 Q9P2W3	CALHM1 CALHM3 FAM26A FAM26C GNAT3 GNB1 GNB3 GNG13 GPR60 GPR70 GPR71 GPRC1A GPRC1D GRM1 GRM4 HBA ITPR3 KIAA1356 LTRPC4 LTRPC5 MGLUR1 MGLUR4 MTR1 NAC2 NAC3 NENA PLCB2 PTC SCN1B SCN2A SCN2A1 SCN2A2 SCN2B SCN3A SCN4B SCN9A T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R20 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R43 TAS2R44 TAS2R46 TAS2R47 TAS2R49 TAS2R5 TAS2R50 TAS2R7 TAS2R8 TR1 TR2 TR3 TRPM4 TRPM5	G58161NS
Acetylcholine regulates insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Muscarinic acetylcholine receptor M3 Myristoylated alanine-rich C-kinase substrate Protein kinase C alpha type	O95837 P17252 P20309 P29966 P29992 P30679 P50148 Q00722 Q01970 Q9NQ66	CHRM3 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ KIAA0581 MACS MARCKS PKCA PLCB1 PLCB2 PLCB3 PRKACA PRKCA PRKCSL
G beta:gamma signalling through PLC beta	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q00722 Q01970 Q9HAV0 Q9NQ66 Q9P2W3 Q9UBI6 Q9UK08	GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0581 PLCB1 PLCB2 PLCB3
Presynaptic function of Kainate receptors	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Glutamate receptor ionotropic, kainate 3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P61952 P62873 P62879 P63211 P63215 P63218 Q00722 Q01970 Q13003 Q9HAV0 Q9NQ66 Q9P2W3 Q9UBI6 Q9UK08	GLUR7 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GRIK3 KIAA0581 PLCB1 PLCB2 PLCB3
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Free fatty acid receptor 1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15	O14842 O95837 P29992 P30679 P50148 Q00722 Q01970 Q9NQ66	FFAR1 GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ GPR40 KIAA0581 PLCB1 PLCB2 PLCB3
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 Calcineurin subunit B type 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calmodulin-1 Catenin beta-1 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-6 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-2 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Helicase MOV-10 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Lymphoid enhancer-binding factor 1 Mitogen-activated protein kinase kinase kinase 7 Nuclear factor of activated T-cells, cytoplasmic 1 Protein Wnt-11 Protein Wnt-5a Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Protein kinase C alpha type Protein phosphatase 3 catalytic subunit alpha Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Serine/threonine-protein kinase NLK Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7 Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein cGMP-dependent protein kinase 1 cGMP-dependent protein kinase 2	O14610 O14775 O43318 O60262 O60353 O95644 O96014 P09471 P0DP23 P16298 P16499 P16520 P17252 P18545 P19087 P35222 P35913 P36402 P41221 P50150 P50151 P59768 P61952 P62873 P62879 P63098 P63211 P63215 P63218 Q00722 Q01970 Q08209 Q13237 Q13467 Q13976 Q14332 Q14571 Q14573 Q14643 Q8NDV7 Q9H9G7 Q9HAV0 Q9HCE1 Q9HCJ0 Q9HCK5 Q9HCS4 Q9NPG1 Q9NQ66 Q9NQB0 Q9P2W3 Q9UBE8 Q9UBI6 Q9UJU2 Q9UK08 Q9UKV8 Q9UL18 Q9ULV1 Q9UPQ9 Q9UQM7	AGO1 AGO2 AGO3 AGO4 C2orf31 CAGH26 CALM CALM1 CALNA CALNA2 CALNB CAM CAM1 CAMK2A CAMKA CNA CNA2 CNB CTNNB CTNNB1 EIF2C1 EIF2C2 EIF2C3 EIF2C4 FZD2 FZD3 FZD4 FZD5 FZD6 GNAO1 GNAT2 GNATC GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 INSP3R1 ITPR1 ITPR2 ITPR3 KIAA0581 KIAA0968 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 LAK1 LEF1 MAP3K7 MOV10 NFAT2 NFATC NFATC1 NLK PDE6A PDE6B PDE6G PDEA PDEB PDEG PKCA PLCB1 PLCB2 PLCB3 PPP3CA PPP3CB PPP3R1 PRKACA PRKCA PRKG1 PRKG1B PRKG2 PRKGR1A PRKGR1B PRKGR2 TAK1 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 TNRC6 TNRC6A TNRC6B TNRC6C WNT11 WNT5A
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Inositol 1,4,5-trisphosphate receptor type 2 Inositol 1,4,5-trisphosphate receptor type 3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 S-adenosylhomocysteine hydrolase-like protein 1	O43865 O95837 P29992 P30679 P50148 Q00722 Q01970 Q14571 Q14573 Q14643 Q15147 Q9NQ66	AHCYL1 DCAL GA11 GAQ GNA11 GNA14 GNA15 GNA16 GNAQ INSP3R1 IRBIT ITPR1 ITPR2 ITPR3 KIAA0581 PLCB1 PLCB2 PLCB3 PLCB4 XPVKONA
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Amyloid-beta precursor protein Angiotensinogen Annexin A1 B1 bradykinin receptor B2 bradykinin receptor Beta-adrenergic receptor kinase 1 Bombesin receptor subtype-3 Chemokine XC receptor 1 Cholecystokinin receptor type A Cholecystokinin Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Cytokine SCM-1 beta Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Extracellular calcium-sensing receptor Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3 Free fatty acid receptor 4 G protein-coupled receptor kinase 5 G-protein coupled receptor 143 G-protein coupled receptor 39 G-protein coupled receptor 4 G-protein coupled receptor family C group 6 member A Gastrin-releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Gastrin Glucagon receptor Gonadotropin-releasing hormone receptor Growth hormone secretagogue receptor type 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha-15 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Histamine H1 receptor Humanin Hypocretin neuropeptide precursor Kalirin KiSS-1 receptor Kininogen-1 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Lymphotactin Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 4 Lysophosphatidic acid receptor 5 Lysophosphatidic acid receptor 6 Melanin-concentrating hormone receptor 1 Melanin-concentrating hormone receptor 2 Melanopsin Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 5 Metastasis-suppressor KiSS-1 Motilin receptor Muscarinic acetylcholine receptor M1 Muscarinic acetylcholine receptor M3 Muscarinic acetylcholine receptor M5 N-formyl peptide receptor 2 Neuromedin-B receptor Neuromedin-B Neuromedin-K receptor Neuromedin-S Neuromedin-U receptor 1 Neuromedin-U receptor 2 Neuromedin-U Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Neuropeptide S receptor Neuropeptide S Neurotensin receptor type 1 Neurotensin receptor type 2 Neurotensin/neuromedin N Orexigenic neuropeptide QRFP Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Ovarian cancer G-protein coupled receptor 1 Oxytocin receptor Oxytocin-neurophysin 1 P2Y purinoceptor 11 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y purinoceptor 6 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-activating factor receptor Pro-FMRFamide-related neuropeptide FF Pro-MCH Pro-glucagon Pro-thyrotropin-releasing hormone Probable G-protein coupled receptor 132 Progonadoliberin-1 Progonadoliberin-2 Prokineticin receptor 1 Prokineticin receptor 2 Prokineticin-1 Prokineticin-2 Promotilin Prostaglandin E2 receptor EP1 subtype Prostaglandin F2-alpha receptor Protachykinin-1 Proteinase-activated receptor 1 Proteinase-activated receptor 2 Proteinase-activated receptor 3 Proteinase-activated receptor 4 Prothrombin Psychosine receptor Putative P2Y purinoceptor 10 Putative gonadotropin-releasing hormone II receptor Pyroglutamylated RF-amide peptide receptor Regulator of G-protein signaling 13 Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 18 Regulator of G-protein signaling 19 Regulator of G-protein signaling 1 Regulator of G-protein signaling 21 Regulator of G-protein signaling 2 Regulator of G-protein signaling 3 Regulator of G-protein signaling 4 Regulator of G-protein signaling 5 Regulator of G-protein signaling protein-like Rho guanine nucleotide exchange factor 25 Serum amyloid A-1 protein Substance-K receptor Substance-P receptor Tachykinin-3 Thromboxane A2 receptor Thyrotropin-releasing hormone receptor Triple functional domain protein Type-1 angiotensin II receptor Tyrosine-protein kinase BTK Uracil nucleotide/cysteinyl leukotriene receptor Urotensin-2 receptor Urotensin-2 Urotensin-2B Vasopressin V1a receptor Vasopressin V1b receptor Vasopressin-neurophysin 2-copeptin	A5PLK6 O00254 O00398 O00459 O14610 O14775 O14842 O14843 O14921 O15130 O15492 O15539 O15552 O43193 O43194 O43555 O43612 O43613 O43614 O60229 O60262 O75962 O95399 O95665 O95837 P00734 P01019 P01042 P01148 P01178 P01185 P01275 P01350 P04083 P05067 P05305 P06307 P07492 P08912 P08949 P0C0P6 P0DJI8 P11229 P12872 P14138 P16520 P20309 P20366 P20382 P20396 P20800 P21452 P21731 P24530 P25090 P25098 P25100 P25101 P25103 P25105 P25116 P27986 P28223 P28335 P28336 P29371 P29992 P30411 P30550 P30556 P30559 P30679 P30968 P30989 P30990 P32238 P32239 P32247 P34947 P34981 P34995 P35348 P35367 P35368 P37288 P41180 P41220 P41231 P41594 P41595 P42336 P43088 P43657 P46093 P46094 P46663 P47871 P47900 P47901 P47992 P48645 P49795 P49796 P49798 P50148 P50150 P50151 P51810 P55085 P58294 P59768 P61952 P62873 P62879 P63211 P63215 P63218 P83859 Q00722 Q01970 Q06187 Q08116 Q13255 Q13304 Q15077 Q15147 Q15722 Q15726 Q15743 Q2M5E4 Q5H8A3 Q5NUL3 Q5T6X5 Q6W5P4 Q765I0 Q86VW2 Q8IVG9 Q8IYL9 Q8NFJ6 Q8TCW9 Q92569 Q92633 Q92847 Q969F8 Q969V1 Q96G91 Q96P65 Q96P88 Q96RI0 Q99677 Q99705 Q9GZQ4 Q9GZQ6 Q9H1C0 Q9HAV0 Q9HB89 Q9HBW0 Q9HC23 Q9NPC1 Q9NQ66 Q9NS28 Q9NS75 Q9P2W3 Q9UBD3 Q9UBI6 Q9UBY5 Q9UGC6 Q9UHF0 Q9UHM6 Q9UK08 Q9UKP6 Q9UNW8 Q9Y271 Q9Y5X5	1R20 A4 AD1 ADRA1A ADRA1B ADRA1C ADRA1D ADRBK1 AGMX1 AGT AGTR1 AGTR1A AGTR1B ANX1 ANXA1 APP ARHGEF25 ARVP AT2R1 AT2R1B ATK AVP AVPR1 AVPR1A AVPR1B AVPR3 AXOR12 BARK BARK1 BDK BDKRB1 BDKRB2 BKR2 BL34 BLT BLT1 BLT2R BLTR BLTR2 BPK BRADYB1 BRS3 BTK BV8 CASR CCK CCKAR CCKBR CCKRA CCKRB CCXCR1 CF2R CHRM1 CHRM3 CHRM5 CMKRL1 CYSLT1 CYSLT2 CYSLT2R CYSLTR1 CYSLTR2 DUET DUO EDG2 EDG4 EDG7 EDN1 EDN2 EDN3 EDNRA EDNRB ETA ETRA ETRB F2 F2R F2RL1 F2RL2 F2RL3 FFA2 FFAR1 FFAR2 FFAR3 FFAR4 FPR2 FPRH1 FPRL1 G0S8 G2A GA11 GAIP GAQ GAS GAST GCG GCGR GEFT GHSR GNA11 GNA14 GNA15 GNA16 GNAI3IP GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GNRH GNRH1 GNRH2 GNRHR GNRHR2 GPCR43 GPR103 GPR11 GPR120 GPR129 GPR132 GPR14 GPR143 GPR145 GPR147 GPR154 GPR16 GPR17 GPR23 GPR24 GPR38 GPR39 GPR4 GPR40 GPR41 GPR43 GPR5 GPR54 GPR65 GPR66 GPR68 GPR73 GPR73L1 GPR74 GPR92 GPR93 GPRA GPRC1A GPRC1E GPRC2A GPRC6A GPRK5 GRB1 GRH GRHR GRK2 GRK5 GRM1 GRM5 GRP GRPR HAPIP HCRT HCRTR1 HCRTR2 HN HRH1 HTR1C HTR2 HTR2A HTR2B HTR2C IER1 KALRN KIAA0581 KISS1 KISS1R KNG KNG1 LHRH LPA1 LPA2 LPA3 LPA4 LPAR1 LPAR2 LPAR3 LPAR4 LPAR5 LPAR6 LPC1 LTB4R LTB4R2 LTN LXA4R MCH MCHR1 MCHR2 MGLUR1 MGLUR5 MLN MLNR MOP MT-RNR2 MTLR MTLR1 NK1R NK2R NK3R NKA NKNA NKNAR NKNB NMB NMBR NMS NMU NMU2R NMUR1 NMUR2 NPFF NPFF1 NPFF2 NPFFR1 NPFFR2 NPGPR NPS NPSR1 NTRR NTS NTSR1 NTSR2 O3FAR1 OA1 OGR1 OPN4 OT OX OXT OXTR P2RU1 P2RY1 P2RY10 P2RY11 P2RY2 P2RY5 P2RY6 P2RY7 P2RY9 PAFR PAR1 PAR2 PAR3 PAR4 PCAR1 PGR14 PGR4 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKR1 PKR2 PLCB1 PLCB2 PLCB3 PLCB4 PMCH PPORX PPOX PROK1 PROK2 PROKR1 PROKR2 PTAFR PTGER1 PTGFR QRFP QRFPR RGS1 RGS13 RGS16 RGS17 RGS18 RGS19 RGS2 RGS21 RGS3 RGS4 RGS5 RGSL RGSL1 RGSL2 RGSR RGSZ2 SAA1 SCYC1 SCYC2 SERPINA8 SLC1 SLT TAC1 TAC1R TAC2 TAC2R TAC3 TAC3R TACR1 TACR2 TACR3 TBXA2R TDAG8 TGR1 TR TRAD TRH TRHR TRIO URP UTS2 UTS2B UTS2D UTS2R VP VPR3 XCL1 XCL2 XCR1
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 5'-3' exonuclease PLD4 Calmodulin-1 Inositol polyphosphate 5-phosphatase OCRL Inositol-tetrakisphosphate 1-kinase Inositol-trisphosphate 3-kinase A Inositol-trisphosphate 3-kinase B Inositol-trisphosphate 3-kinase C Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Synaptojanin-1 Type II inositol 1,4,5-trisphosphate 5-phosphatase	O15357 O43426 O75038 P0DP23 P16885 P19174 P23677 P27987 P32019 P51178 P60484 Q00722 Q01968 Q01970 Q13572 Q15147 Q15735 Q4KWH8 Q86YW0 Q8N3E9 Q92835 Q96BZ4 Q96DU7 Q9BRC7 Q9NQ66 Q9P212	C14orf175 CALM CALM1 CAM CAM1 INPP5B INPP5D INPP5J INPPL1 IP3KC ITPK1 ITPKA ITPKB ITPKC KIAA0450 KIAA0581 KIAA0910 KIAA1069 KIAA1516 KIAA1964 MMAC1 OCRL OCRL1 OCRL2 PIB5PA PIPP PLC1 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE PLCE1 PLCG1 PLCG2 PLCH1 PLCH2 PLCL3 PLCL4 PLCZ1 PLD4 PPLC PTEN SHIP SHIP1 SHIP2 SYNJ1 TEP1
Synthesis of PIPs at the late endosome membrane	1-phosphatidylinositol 3-phosphate 5-kinase Myotubularin-related protein 2 Myotubularin-related protein 4 Myotubularin-related protein 7 Myotubularin-related protein 9 Myotubularin Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphoinositide 3-kinase regulatory subunit 4 Polyphosphoinositide phosphatase Protein VAC14 homolog	O00443 Q08AM6 Q13496 Q13614 Q8NEB9 Q92562 Q96QG7 Q99570 Q9NYA4 Q9Y216 Q9Y2I7	C8orf9 CG2 FIG4 KIAA0274 KIAA0647 KIAA0981 KIAA1073 MTM1 MTMR2 MTMR4 MTMR7 MTMR8 MTMR9 PIK3C2A PIK3C3 PIK3R4 PIKFYVE PIP5K3 SAC3 TAX1BP2 TRX VAC14 VPS15 VPS34 ZFYVE11
Synthesis of PIPs at the early endosome membrane	1-phosphatidylinositol 3-phosphate 5-kinase Inositol polyphosphate 4-phosphatase type II Inositol polyphosphate-4-phosphatase type I A Myotubularin-related protein 10 Myotubularin-related protein 12 Myotubularin-related protein 2 Myotubularin-related protein 4 Myotubularin Phosphatidylinositide phosphatase SAC2 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphoinositide 3-kinase regulatory subunit 4 Polyphosphoinositide phosphatase Protein VAC14 homolog	O00443 O15327 Q08AM6 Q13496 Q13614 Q8NEB9 Q8TCG2 Q92562 Q96PE3 Q99570 Q9BTU6 Q9C0I1 Q9NXD2 Q9NYA4 Q9Y2H2 Q9Y2I7	CG2 FIG4 INPP4A INPP4B INPP5F KIAA0274 KIAA0647 KIAA0966 KIAA0981 KIAA1073 KIAA1682 MTM1 MTMR10 MTMR12 MTMR2 MTMR4 PI4K2A PI4K2B PIK3C2A PIK3C3 PIK3R4 PIKFYVE PIP3AP PIP5K3 SAC2 SAC3 TAX1BP2 TRX VAC14 VPS15 VPS34 ZFYVE11
Synthesis of PIPs at the Golgi membrane	1-phosphatidylinositol 3-phosphate 5-kinase ADP-ribosylation factor 1 ADP-ribosylation factor 3 Inositol polyphosphate 5-phosphatase OCRL Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 4-kinase alpha Phosphatidylinositol 4-kinase beta Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha Phosphatidylinositol polyphosphate 5-phosphatase type IV Phosphatidylinositol-3-phosphatase SAC1 Phosphoinositide 3-kinase regulatory subunit 4 Polyphosphoinositide phosphatase Protein VAC14 homolog Putative tyrosine-protein phosphatase TPTE	O00443 O75747 P42356 P56180 P61204 P84077 Q01968 Q08AM6 Q6XPS3 Q8NEB9 Q8TCG2 Q92562 Q99570 Q9BTU6 Q9NRR6 Q9NTJ5 Q9UBF8 Q9Y2I7	ARF1 ARF3 FIG4 INPP5E KIAA0274 KIAA0851 KIAA0981 OCRL OCRL1 PI4K2A PI4K2B PI4KA PI4KB PIK3C2A PIK3C2G PIK3C3 PIK3R4 PIK4 PIK4CA PIK4CB PIKFYVE PIP5K3 SAC1 SAC3 SACM1L TAX1BP2 TPIP TPTE TPTE2 TRX VAC14 VPS15 VPS34

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