GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1626 - 1650** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Anchoring fibril formation	Bone morphogenetic protein 1 Collagen alpha-1(VII) chain Laminin subunit alpha-3 Laminin subunit beta-3 Laminin subunit gamma-2 Tolloid-like protein 1 Tolloid-like protein 2	O43897 P13497 Q02388 Q13751 Q13753 Q16787 Q9Y6L7	BMP1 COL7A1 KIAA0932 LAMA3 LAMB2T LAMB3 LAMC2 LAMNA LAMNB1 LAMNB2 PCOLC TLL TLL1 TLL2	Homo sapiens (human)
Disassembly of the destruction complex and recruitment of AXIN to the membrane	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Casein kinase I isoform gamma-2 Catenin beta-1 Caveolin-1 Frizzled-1 Frizzled-2 Frizzled-5 GSK-3-binding protein FRAT2 Glycogen synthase kinase-3 beta Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Protein Wnt-3a Protein Wnt-8a Protein Wnt-8b Proto-oncogene FRAT1 Proto-oncogene Wnt-1 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O14640 O14641 O15169 O75197 O75474 O75581 P04628 P25054 P30153 P30154 P35222 P48729 P49841 P56704 P62714 P67775 P78368 Q03135 Q13362 Q13467 Q14332 Q14738 Q15172 Q15173 Q16537 Q5JTC6 Q92837 Q92997 Q93098 Q9H1J5 Q9UP38	AMER1 APC AXIN AXIN1 C2orf31 CAV CAV1 CK1G2 CSNK1A1 CSNK1G2 CTNNB CTNNB1 DP2.5 DVL1 DVL2 DVL3 FAM123B FRAT1 FRAT2 FZD1 FZD2 FZD5 GSK3B INT1 KIAA0044 KIAA0208 LR3 LRP5 LRP6 LRP7 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WNT1 WNT3A WNT8A WNT8B WNT8D WTX	Homo sapiens (human)
HS-GAG biosynthesis	Agrin Basement membrane-specific heparan sulfate proteoglycan core protein Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 D-glucuronyl C5-epimerase Exostosin-1 Exostosin-2 Glypican-1 Glypican-2 Glypican-3 Glypican-4 Glypican-5 Glypican-6 Heparan sulfate 2-O-sulfotransferase 1 Heparan sulfate glucosamine 3-O-sulfotransferase 1 Heparan sulfate glucosamine 3-O-sulfotransferase 2 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 Heparan sulfate glucosamine 3-O-sulfotransferase 4 Heparan sulfate glucosamine 3-O-sulfotransferase 5 Heparan sulfate glucosamine 3-O-sulfotransferase 6 Heparan-sulfate 6-O-sulfotransferase 1 Heparan-sulfate 6-O-sulfotransferase 2 Heparan-sulfate 6-O-sulfotransferase 3 Nucleotide sugar transporter SLC35D2 Syndecan-1 Syndecan-2 Syndecan-3 Syndecan-4	O00468 O14792 O60243 O75056 O75487 O94923 O95803 P18827 P31431 P34741 P35052 P51654 P52848 P52849 P78333 P98160 Q16394 Q76EJ3 Q7LGA3 Q8IZP7 Q8IZT8 Q8N158 Q93063 Q96MM7 Q96QI5 Q9H3R1 Q9Y278 Q9Y625 Q9Y661 Q9Y662 Q9Y663	3OST 3OST1 3OST2 3OST3A1 3OST3B1 3OST4 3OST5 AGRIN AGRN EXT1 EXT2 GLCE GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 HFRC HS2ST HS2ST1 HS3OST5 HS3ST1 HS3ST2 HS3ST3A HS3ST3A1 HS3ST3B HS3ST3B1 HS3ST4 HS3ST5 HS3ST6 HS6ST HS6ST1 HS6ST2 HS6ST3 HSPG1 HSPG2 HSST HSST1 HSST2 HSST3 HSST4 KIAA0448 KIAA0468 KIAA0836 NDST1 NDST2 NDST3 NDST4 OCI5 SDC SDC1 SDC2 SDC3 SDC4 SLC35D2 UGTREL8	Homo sapiens (human)
Formation of lateral plate mesoderm	Bone morphogenetic protein 4 Forkhead box protein F1 Indian hedgehog protein Sonic hedgehog protein Transcription factor GATA-4	P12644 P43694 Q12946 Q14623 Q15465	BMP2B BMP4 DVR4 FKHL5 FOXF1 FREAC1 GATA4 IHH SHH	Homo sapiens (human)
Paradoxical activation of RAF signaling by kinase inactive BRAF	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB	Homo sapiens (human)
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Cyclin-dependent kinase inhibitor 1 Lysine-specific demethylase 5B Myc proto-oncogene protein Transcription factor AP-2 gamma Transcription factor AP-2-alpha	P01106 P05549 P38936 Q92754 Q9UGL1	AP2TF BHLHE39 CAP20 CDKN1 CDKN1A CIP1 JARID1B KDM5B MDA6 MYC PIC1 PLU1 RBBP2H1 SDI1 TFAP2 TFAP2A TFAP2C WAF1	Homo sapiens (human)
Regulation of innate immune responses to cytosolic DNA	E3 ubiquitin-protein ligase DTX4 E3 ubiquitin-protein ligase TRIM21 E3 ubiquitin-protein ligase TRIM32 E3 ubiquitin-protein ligase TRIM56 Interferon regulatory factor 3 NACHT, LRR and PYD domains-containing protein 4 Polyubiquitin-B Polyubiquitin-C Probable ATP-dependent RNA helicase DDX41 Serine/threonine-protein kinase TBK1 Stimulator of interferon genes protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Z-DNA-binding protein 1	P0CG47 P0CG48 P19474 P62979 P62987 Q13049 Q14653 Q86WV6 Q96MN2 Q9BRZ2 Q9H171 Q9UHD2 Q9UJV9 Q9Y2E6	ABS C20orf183 DDX41 DLM1 DTX4 ERIS HT2A IRF3 KIAA0937 MITA NAK NALP4 NLRP4 PAN2 PYPAF4 RNF109 RNF155 RNF81 RNH2 RO52 RPS27A SSA1 STING STING1 TBK1 TMEM173 TRIM21 TRIM32 TRIM56 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 ZBP1	Homo sapiens (human)
Phase 1 - inactivation of fast Na+ channels	A-type potassium channel modulatory protein KCNIP1 A-type potassium channel modulatory protein KCNIP2 A-type voltage-gated potassium channel KCND1 A-type voltage-gated potassium channel KCND2 A-type voltage-gated potassium channel KCND3 Calsenilin Kv channel-interacting protein 4	Q6PIL6 Q9NS61 Q9NSA2 Q9NZI2 Q9NZV8 Q9UK17 Q9Y2W7	CALP CSEN DREAM KCHIP1 KCHIP2 KCHIP3 KCHIP4 KCND1 KCND2 KCND3 KCNIP1 KCNIP2 KCNIP3 KCNIP4 KIAA1044 VABP	Homo sapiens (human)
FLT3 mutants bind TKIs	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
Dectin-1 mediated noncanonical NF-kB signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 14 NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme Ubc12 Nuclear factor NF-kappa-B p100 subunit Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 S-phase kinase-associated protein 1 Transcription factor RelB Transcription factor p65 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O15111 O43242 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P61081 P62191 P62195 P62333 P62979 P62987 P63208 Q00653 Q01201 Q04206 Q13200 Q13616 Q15008 Q16186 Q8TBC4 Q99436 Q99460 Q99558 Q9UKB1 Q9UNM6 Q9Y297	ADRM1 BTRC BTRCP BTRCP2 C7orf76 CHUK CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B GP110 HC2 HC3 HC8 HC9 HSPC IKKA KIAA0107 KIAA0696 LMPX LMPY LYT10 MAP3K14 MB1 MIP224 MOV34L MSS1 NFKB2 NFKB3 NIK NU OCP2 PFAAP4 POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RELA RELB RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TBP1 TBP7 TCEB1L TCF16 TRAP2 UBA3 UBA52 UBA80 UBB UBC UBC12 UBCEP1 UBCEP2 UBE1C UBE2M X Y Z	Homo sapiens (human)
RORA activates gene expression	3'-5' exoribonuclease HELZ2 CREB-binding protein Carnitine O-palmitoyltransferase 1, liver isoform Chromodomain-helicase-DNA-binding protein 9 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Histone acetyltransferase p300 Histone-arginine methyltransferase CARM1 Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor ROR-alpha Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Sterol regulatory element-binding protein 1 Trimethylguanosine synthase	O60907 P19793 P35398 P36956 P50416 Q07869 Q09472 Q14686 Q15596 Q15648 Q15788 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q9BYK8 Q9BZK7	AIB3 ARC205 BAF60C BHLHD1 BHLHE74 BHLHE75 CARM1 CBP CHD9 CPT1 CPT1A CREBBP CRSP1 CRSP200 DRIP205 DRIP230 EP300 HCA137 HELZ2 IRA1 KIAA0181 KIAA0308 KIAA1769 KISH2 MED1 NCOA1 NCOA2 NCOA6 NCOA6IP NR1C1 NR1F1 NR2B1 P300 PBP PIMT PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RORA RXRA RZRA SMARCD3 SRC1 SRC2 SREBF1 SREBP1 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2	Homo sapiens (human)
AKT phosphorylates targets in the nucleus	Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Forkhead box protein O6 Nuclear receptor subfamily 4immunitygroup A member 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Ribosomal protein S6 kinase beta-2	A8MYZ6 O43524 P22736 P31749 P31751 P98177 Q12778 Q9UBS0 Q9Y243	AFX AFX1 AKT1 AKT2 AKT3 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A FOXO4 FOXO6 GFRP1 HMR MLLT7 NAK1 NR4A1 PKB PKBG RAC RPS6KB2 STK14B	Homo sapiens (human)
Response of EIF2AK4 (GCN2) to amino acid deficiency	Asparagine synthetase [glutamine-hydrolyzing] CCAAT/enhancer-binding protein beta CCAAT/enhancer-binding protein gamma Cyclic AMP-dependent transcription factor ATF-2 Cyclic AMP-dependent transcription factor ATF-3 Cyclic AMP-dependent transcription factor ATF-4 DNA damage-inducible transcript 3 protein Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL29 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL34 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL37 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23 Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5 Large ribosomal subunit protein uL6 Protein IMPACT Ribosomal protein eL22-like Ribosomal protein eL39-like 2 Ribosomal protein eL42-like Ribosomal protein eS27-like Ribosomal protein uL16-like Ribosomal protein uL24-like Ribosomal protein uL3-like Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS32 Small ribosomal subunit protein eS4, X isoform Small ribosomal subunit protein eS4, Y isoform 1 Small ribosomal subunit protein eS4, Y isoform 2 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Stalled ribosome sensor GCN1 Tribbles homolog 3 Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein eIF-2-alpha kinase GCN2	P05198 P05386 P05387 P05388 P08243 P08708 P08865 P15336 P15880 P17676 P18077 P18124 P18621 P18847 P18848 P20042 P22090 P23396 P25398 P26373 P27635 P30050 P32969 P35268 P35638 P36578 P39019 P39023 P40429 P41091 P42677 P42766 P46776 P46777 P46778 P46779 P46781 P46782 P46783 P47914 P49207 P50914 P53567 P60866 P61247 P61254 P61313 P61353 P61513 P61927 P62081 P62241 P62244 P62249 P62263 P62266 P62269 P62273 P62277 P62280 P62424 P62701 P62750 P62753 P62829 P62841 P62847 P62851 P62854 P62857 P62861 P62888 P62891 P62899 P62906 P62910 P62913 P62917 P62945 P62979 P62987 P63173 P63220 P83731 P83881 P84098 Q02543 Q02878 Q07020 Q6P5R6 Q71UM5 Q8TD47 Q92616 Q92901 Q969Q0 Q96EH5 Q96L21 Q96RU7 Q9P2K8 Q9P2X3 Q9UNX3 Q9Y3U8	ASNS ATF2 ATF3 ATF4 BBC1 C20orf97 CCG2 CEBPB CEBPG CHOP CHOP10 CREB2 CREBP1 D11S2243E D6S218E DDIT3 DXS648E EC45 EIF2A EIF2AK4 EIF2B EIF2G EIF2S1 EIF2S2 EIF2S3 FAU FTE1 GADD153 GCN1 GCN1L1 GCN2 IMPACT KIAA0219 KIAA1338 LAMBR LAMR1 MFTL MPS1 NEDD6 NIPK QM RIG RPL1 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL26P1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL39L RPL39L1 RPL3L RPL4 RPL41 RPL44 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPL9P7 RPL9P8 RPL9P9 RPLP0 RPLP1 RPLP2 RPP2 RPS10 RPS11 RPS12 RPS13 RPS14 RPS15 RPS15A RPS16 RPS17 RPS17L RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4 RPS4X RPS4Y RPS4Y1 RPS4Y2 RPS4Y2P RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RRP1 SCAR SKIP3 SURF-3 SURF3 TCF5 TRB3 TRIB3 TS11 TXREB TXREB1 UBA52 UBA80 UBCEP1 UBCEP2	Homo sapiens (human)
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin-1 Calmodulin-lysine N-methyltransferase Cyclic nucleotide-gated channel alpha-1 Cyclic nucleotide-gated channel beta-1 Glycylpeptide N-tetradecanoyltransferase 1 Glycylpeptide N-tetradecanoyltransferase 2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanylyl cyclase-activating protein 1 Guanylyl cyclase-activating protein 2 Guanylyl cyclase-activating protein 3 Methionine aminopeptidase 1 Methionine aminopeptidase 2 Protein farnesyltransferase subunit beta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Protein kinase C alpha type Protein kinase C theta type Recoverin Regulator of G-protein signaling 9-binding protein Retinal guanylyl cyclase 1 Retinal guanylyl cyclase 2 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin kinase GRK1 Rhodopsin kinase GRK7 Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Serine/threonine-protein phosphatase with EF-hands 1	O14829 O60551 O95843 P08100 P0DP23 P10523 P11488 P16499 P17252 P18545 P29973 P30419 P35243 P35913 P43080 P49354 P49356 P50579 P51841 P53582 P62873 P63211 Q02846 Q04759 Q14028 Q15835 Q6ZS82 Q7Z624 Q8WTQ7 Q9UMX6	C2orf34 C6orf131 CALM CALM1 CAM CAM1 CAMKMT CLNMT CNCG CNCG1 CNCG2 CNCG3L CNCG4 CNGA1 CNGB1 CORD6 FNTA FNTB GCAP GCAP1 GCAP2 GCAP3 GNAT1 GNATR GNB1 GNGT1 GPRK7 GRK1 GRK7 GUC1A4 GUC2D GUC2F GUCA1 GUCA1A GUCA1B GUCA1C GUCY2D GUCY2F KIAA0094 METAP1 METAP2 MNPEP NMT NMT1 NMT2 OPN2 P67EIF2 PDE6A PDE6B PDE6G PDEA PDEB PDEG PKCA PPEF PPEF1 PPP7C PRKACA PRKCA PRKCQ PRKCT R9AP RCNC2 RCV1 RCVRN RETGC RETGC1 RETGC2 RGS9BP RHO RHOK SAG	Homo sapiens (human)
Glutathione conjugation	Aldo-keto reductase family 1 member A1 Glutathione S-transferase 3, mitochondrial Glutathione S-transferase A1 Glutathione S-transferase A2 Glutathione S-transferase A3 Glutathione S-transferase A4 Glutathione S-transferase A5 Glutathione S-transferase Mu 1 Glutathione S-transferase Mu 2 Glutathione S-transferase Mu 3 Glutathione S-transferase Mu 4 Glutathione S-transferase Mu 5 Glutathione S-transferase P Glutathione S-transferase kappa 1 Glutathione S-transferase omega-1 Glutathione S-transferase omega-2 Glutathione S-transferase theta-1 Glutathione S-transferase theta-2 Glutathione S-transferase theta-2B Hematopoietic prostaglandin D synthase Maleylacetoacetate isomerase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 S-formylglutathione hydrolase	O14880 O15217 O43708 O60760 P08263 P09210 P09211 P09488 P0CG29 P0CG30 P10620 P10768 P14550 P21266 P28161 P30711 P46439 P78417 Q03013 Q16772 Q7RTV2 Q99735 Q9H4Y5 Q9Y2Q3	AKR1A1 ALDR1 ALR ESD FAEES3 GST1 GST12 GST2 GST3 GST4 GST5 GSTA1 GSTA2 GSTA3 GSTA4 GSTA5 GSTK1 GSTM1 GSTM2 GSTM3 GSTM4 GSTM5 GSTO1 GSTO2 GSTP1 GSTS GSTT1 GSTT2 GSTT2B GSTTLP28 GSTZ1 HPGDS MAAI MGST MGST1 MGST2 MGST3 PGDS PTGDS2	Homo sapiens (human)
Interleukin-6 signaling	E3 ubiquitin-protein ligase CBL Interleukin-6 receptor subunit alpha Interleukin-6 receptor subunit beta Interleukin-6 Non-receptor tyrosine-protein kinase TYK2 Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein phosphatase non-receptor type 11	O14543 O60674 P05231 P08887 P22681 P23458 P29597 P40189 P40763 P42224 Q06124	APRF CBL CBL2 CIS3 IFNB2 IL6 IL6R IL6ST JAK1 JAK1A JAK1B JAK2 PTP2C PTPN11 RNF55 SHPTP2 SOCS3 SSI3 STAT1 STAT3 TYK2	Homo sapiens (human)
SUMOylation of DNA damage response and repair proteins	Aladin Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Centrin-2 Chromobox protein homolog 2 Chromobox protein homolog 8 Cohesin subunit SA-1 Cohesin subunit SA-2 DNA repair protein RAD52 homolog DNA repair protein XRCC4 DNA repair protein complementing XP-C cells Double-strand-break repair protein rad21 homolog E3 SUMO-protein ligase CBX4 E3 SUMO-protein ligase NSE2 E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS4 E3 SUMO-protein ligase RanBP2 E3 ubiquitin-protein ligase HERC2 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 E3 ubiquitin-protein ligase RNF168 EP300-interacting inhibitor of differentiation 3 G/T mismatch-specific thymine DNA glycosylase Histone deacetylase 7 Mediator of DNA damage checkpoint protein 1 Non-structural maintenance of chromosomes element 1 homolog Non-structural maintenance of chromosomes element 3 homolog Non-structural maintenance of chromosomes element 4 homolog A Nuclear autoantigen Sp-100 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Poly [ADP-ribose] polymerase 1 Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 Protein PML Protein SEC13 homolog RecQ-like DNA helicase BLM Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Structural maintenance of chromosomes protein 5 Structural maintenance of chromosomes protein 6 Tumor suppressor ARF mRNA export factor RAE1	A8CG34 O00257 O15504 O60216 O75694 O75925 O95714 P09874 P12270 P23497 P27694 P29590 P35226 P35227 P35658 P37198 P38398 P41208 P43351 P49790 P49792 P54132 P55735 P55854 P57740 P61956 P63165 P63279 P78364 P78406 Q01831 Q06587 Q12769 Q13426 Q13569 Q14191 Q14676 Q14683 Q14781 Q5SRE5 Q7Z3B4 Q8IXK0 Q8IY18 Q8IYW5 Q8N140 Q8N1F7 Q8N2W9 Q8N3U4 Q8N726 Q8NDX5 Q8NFH3 Q8NFH4 Q8NFH5 Q8TEM1 Q8WUI4 Q8WUM0 Q8WV22 Q8WVM7 Q92621 Q96HA1 Q96MF7 Q96MG7 Q96SB8 Q99496 Q99567 Q9BTX1 Q9BW27 Q9HC52 Q9NRG9 Q9NXX6 Q9UKX7 Q9UQE7	AAAS ADPRT ADRACALA BAM BAP1 BLM BMH BMI1 BRCA1 C10orf86 C7orf14 C8orf36 CAIN CALT CAN CBX2 CBX4 CBX8 CDKN2 CDKN2A CEN2 CETN2 CG1 CSPG6 D3S1231E DDXBP1 DING DXS423E EDR1 EDR2 EDR3 EID3 HCA4 HDAC7 HDAC7A HERC2 HIPI3 HR21 KIAA0023 KIAA0078 KIAA0095 KIAA0169 KIAA0170 KIAA0178 KIAA0197 KIAA0225 KIAA0594 KIAA0618 KIAA0791 KIAA0906 MAGEG1 MDC1 MEL18 MLM MMS21 MP44 MRNP41 MYL NDC1 NDNL2 NFBD1 NPAP60L NSMCE1 NSMCE2 NSMCE3 NSMCE4A NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 NXP1 PARP1 PC3 PCGF2 PCGF4 PCNT1 PH1 PH2 PH3 PHC1 PHC2 PHC3 PIAS1 PIAS4 PIASG PML POM121 POM121A POM121C PP8675 PPOL RAD21 RAD52 RAE1 RANBP2 RC1 RECQ2 RECQ3 RECQL2 RECQL3 REPA1 RING1 RING1A RING1B RNF1 RNF110 RNF168 RNF2 RNF51 RNF53 RNF71 RPA1 RPA70 SA1 SA2 SB1.8 SCC1 SCC3 SEC13 SEC13A SEC13L1 SEC13R SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SMC5 SMC5L1 SMC6 SMC6L1 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SP100 STAG1 STAG2 SUMO1 SUMO2 SUMO3 TDG TMEM48 TPR TRIM19 UBC9 UBCE9 UBE2I UBL1 WRN XPC XPCC XRCC4 ZNF144	Homo sapiens (human)
MAPK6/MAPK4 signaling	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cdc42 effector protein 2 Cdc42 effector protein 3 Cdc42 effector protein 5 Cell division control protein 42 homolog Cyclin-dependent kinase 1 DnaJ homolog subfamily B member 1 Dual specificity protein phosphatase CDC14A Dual specificity protein phosphatase CDC14B ETS translocation variant 4 Exportin-1 Forkhead box protein O1 Forkhead box protein O3 G1/S-specific cyclin-D3 Heat shock protein beta-1 Helicase MOV-10 Insulin-like growth factor 2 mRNA-binding protein 1 Kalirin MAP kinase-activated protein kinase 5 Mitogen-activated protein kinase 4 Mitogen-activated protein kinase 6 Myc proto-oncogene protein Nuclear receptor coactivator 3 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 Ras-related C3 botulinum toxin substrate 1 Septin-7 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Transcription factor Jun Trinucleotide repeat-containing gene 6A protein Trinucleotide repeat-containing gene 6B protein Trinucleotide repeat-containing gene 6C protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein V(D)J recombination-activating protein 1 V(D)J recombination-activating protein 2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma	O00231 O00232 O00487 O14613 O14818 O14980 O43242 O43524 O60229 O60729 O75914 P01106 P04792 P05412 P06493 P0CG47 P0CG48 P15918 P17612 P17980 P20618 P22612 P22694 P25685 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30281 P31152 P35998 P43268 P43686 P48556 P49720 P49721 P51665 P55895 P60896 P60900 P60953 P62191 P62195 P62333 P62979 P62987 P63000 Q12778 Q13153 Q13177 Q13200 Q15008 Q16181 Q16186 Q16659 Q6NZY7 Q8IW41 Q8NDV7 Q99436 Q99460 Q9H9G7 Q9HCE1 Q9HCJ0 Q9HCK5 Q9NZI8 Q9UKI2 Q9UKV8 Q9UL18 Q9UNH5 Q9UNM6 Q9UPQ9 Q9Y6Q9	ADRM1 AGO1 AGO2 AGO3 AGO4 AIB1 BHLHE39 BHLHE42 BORG1 BORG2 BORG3 C7orf76 CAGH26 CCND3 CDC10 CDC14A CDC14B CDC2 CDC28A CDC42 CDC42EP2 CDC42EP3 CDC42EP5 CDK1 CDKN1 CEP2 CEP3 CEP5 CRDBP CRM1 DNAJ1 DNAJB1 DSS1 DUET DUO E1AF EIF2C1 EIF2C2 EIF2C3 EIF2C4 ERK3 ERK4 ETV4 FKHR FKHRL1 FOXO1 FOXO1A FOXO3 FOXO3A GP110 HAPIP HC2 HC3 HC8 HC9 HDJ1 HSP27 HSP28 HSPB1 HSPC HSPF1 IGF2BP1 JUN KALRN KIAA0107 KIAA1093 KIAA1460 KIAA1567 KIAA1582 KIAA1631 LMPX LMPY MAPK4 MAPK6 MAPKAPK5 MB1 MIP224 MOV10 MOV34L MSS1 MYC NCOA3 NU OPHN3 P34CDC2 PAK1 PAK2 PAK3 PEA3 PFAAP4 PKACA POH1 PRAK PRKACA PRKACB PRKACG PRKM4 PRKM6 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RAC1 RAC3 RAG1 RAG2 RNF74 RPS27A SEM1 SEPT7 SEPTIN7 SHFDG1 SHFM1 SUG1 SUG2 TBP1 TBP7 TC25 TNRC6 TNRC6A TNRC6B TNRC6C TRAD TRAM1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VICKZ1 X XPO1 Y Z ZBP1	Homo sapiens (human)
UNC93B1 deficiency - HSE	Protein unc-93 homolog B1 Toll-like receptor 3	O15455 Q9H1C4	TLR3 UNC93 UNC93B UNC93B1	Homo sapiens (human)
Defective Base Excision Repair Associated with NEIL3	Endonuclease 8-like 3	Q8TAT5	NEIL3	Homo sapiens (human)
RHOU GTPase cycle	ARF GTPase-activating protein GIT1 ARF GTPase-activating protein GIT2 Cell division control protein 42 homolog Clathrin heavy chain 1 Cytoplasmic protein NCK2 DEP domain-containing protein 1B Disks large homolog 5 Dystonin Ephrin type-A receptor 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Inactive tyrosine-protein kinase PEAK1 Intersectin-2 NEDD4-like E3 ubiquitin-protein ligase WWP2 Partitioning defective 6 homolog alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Protein-tyrosine kinase 2-beta Proto-oncogene tyrosine-protein kinase Src Ras GTPase-activating-like protein IQGAP1 Rho GTPase-activating protein 30 Rho GTPase-activating protein 31 Rho guanine nucleotide exchange factor 6 Rho guanine nucleotide exchange factor 7 Rho-related GTP-binding protein RhoU SH2/SH3 adapter protein NCK1 SLIT-ROBO Rho GTPase-activating protein 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 2 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase PAK 4 Signal transducing adapter molecule 1 Signal transducing adapter molecule 2 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Thioredoxin-like protein 1 Ubiquitin carboxyl-terminal hydrolase 9X Unconventional myosin-VI Vang-like protein 1 tRNA (34-2'-O)-methyltransferase regulator WDR6	O00308 O00459 O14964 O43396 O43639 O75044 O75886 O75914 O96013 P12931 P16333 P27986 P29317 P46940 P60953 Q00610 Q01082 Q03001 Q13153 Q13177 Q13813 Q14155 Q14161 Q14289 Q15052 Q2M1Z3 Q7L0Q8 Q7Z6I6 Q8TAA9 Q8TDM6 Q8WUY9 Q92783 Q93008 Q9H792 Q9NNW5 Q9NPB6 Q9NZM3 Q9UM54 Q9Y2X7	ARHGAP30 ARHGAP31 ARHGAP34 ARHGEF6 ARHGEF7 ARHU BP230 BP240 BPAG1 CDC42 CDC42L1 CDGAP CLH17 CLTC CLTCL2 COOL1 COOL2 DEPDC1B DFFRX DLG5 DMH DST DT ECK EPHA2 FAK2 FAM FNBP2 G28K GIT1 GIT2 GRB1 GRB4 HBP HGS HRS IQGAP1 ITSN2 KIAA0006 KIAA0034 KIAA0051 KIAA0142 KIAA0148 KIAA0389 KIAA0456 KIAA0583 KIAA0728 KIAA1142 KIAA1204 KIAA1256 KIAA2002 MYO6 NCK NCK1 NCK2 NEAS OPHN3 P85SPR PAK1 PAK2 PAK3 PAK3BP PAK4 PAR6A PARD6A PDLG PEAK1 PIK3R1 PIK3R2 PIXA PIXB PTK2B PYK2 RAFTK RHOU SH3D1B SPTA2 SPTAN1 SPTB2 SPTBN1 SRC SRC1 SRGAP2 SRGAP2A STAM STAM1 STAM2 STB2 SWAP TRP32 TXL TXNL TXNL1 USP9 USP9X VANGL1 WDR6 WRCH1 WWP2 XTP8	Homo sapiens (human)
Inhibition of Signaling by Overexpressed EGFR	Amphiregulin Epidermal growth factor receptor Epigen Pro-epidermal growth factor Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protransforming growth factor alpha	O14944 P00533 P01133 P01135 P15514 P35070 Q6UW88 Q99075	AREG AREGB BTC DTR DTS EGF EGFR EPGN ERBB ERBB1 EREG HBEGF HEGFL HER1 SDGF TGFA	Homo sapiens (human)
Activation of NF-kappaB in B cells	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell lymphoma/leukemia 10 Caspase recruitment domain-containing protein 11 Cullin-1 F-box/WD repeat-containing protein 11 F-box/WD repeat-containing protein 1A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Mitogen-activated protein kinase kinase kinase 7 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor beta NF-kappa-B inhibitor epsilon Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein kinase C beta type Proto-oncogene c-Rel S-phase kinase-associated protein 1 Transcription factor p65 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00221 O00231 O00232 O00487 O14818 O14920 O15111 O43242 O43318 O95999 P05771 P0CG47 P0CG48 P17980 P19838 P20618 P25786 P25787 P25788 P25789 P25963 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P60896 P60900 P62191 P62195 P62333 P62979 P62987 P63208 Q04206 Q04864 Q13200 Q13616 Q15008 Q15653 Q16186 Q99436 Q99460 Q9BXL7 Q9UDY8 Q9UKB1 Q9UNM6 Q9Y297 Q9Y6K9	ADRM1 BCL10 BTRC BTRCP BTRCP2 C7orf76 CARD11 CARMA1 CHUK CIPER CLAP CUL1 DSS1 EMC19 FBW1A FBW1B FBXW11 FBXW1A FBXW1B FIP3 GP110 HC2 HC3 HC8 HC9 HSPC IKBA IKBB IKBE IKBKB IKBKG IKKA IKKB KIAA0107 KIAA0696 LMPX LMPY MAD3 MALT1 MAP3K7 MB1 MIP224 MLT MOV34L MSS1 NEMO NFKB1 NFKB3 NFKBI NFKBIA NFKBIB NFKBIE NU OCP2 PFAAP4 PKCB POH1 PRKCB PRKCB1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 REL RELA RPS27A SEM1 SHFDG1 SHFM1 SKP1 SKP1A SUG1 SUG2 TAK1 TBP1 TBP7 TCEB1L TCF16 TRAP2 TRIP9 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 X Y Z	Homo sapiens (human)
Loss-of-function mutations in DLD cause MSUD3/DLDD	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial Dihydrolipoyl dehydrogenase, mitochondrial Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial	P09622 P11182 P12694 P21953	BCATE2 BCKDHA BCKDHB BCKDHE2 DBT DLD GCSL LAD PHE3	Homo sapiens (human)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	28S rRNA (cytosine(4447)-C(5))-methyltransferase 60 kDa heat shock protein, mitochondrial Myb-related protein B Nucleophosmin Transcription factor AP-2-alpha	P05549 P06748 P10244 P10809 P46087	AP2TF BMYB HSP60 HSPD1 MYBL2 NOL1 NOP2 NPM NPM1 NSUN1 TFAP2 TFAP2A	Homo sapiens (human)

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