GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1926 - 1950** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
GRB7 events in ERBB2 signaling	Growth factor receptor-bound protein 7 Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Receptor tyrosine-protein kinase erbB-2	O14511 P04626 Q02297 Q14451	ERBB2 GGF GRB7 HER2 HGL HRGA MLN19 NDF NEU NGL NRG1 NRG2 NTAK SMDF	Homo sapiens (human)
Transcriptional regulation of pluripotent stem cells	Endothelial PAS domain-containing protein 1 Homeobox protein NANOG Hypoxia-inducible factor 3-alpha Krueppel-like factor 4 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 4 POU domain, class 5, transcription factor 1 PR domain zinc finger protein 14 Pre-B-cell leukemia transcription factor 1 Protein lin-28 homolog A Sal-like protein 4 Signal transducer and activator of transcription 3 Steroidogenic factor 1 Transcription factor SOX-2 Zinc finger and SCAN domain-containing protein 10 Zinc finger protein ZIC 3	O43474 O60481 P40424 P40763 P48431 Q01860 Q13285 Q13485 Q15796 Q96SZ4 Q99814 Q9GZV8 Q9H9S0 Q9H9Z2 Q9UJQ4 Q9Y2N7	AD4BP APRF BHLHE17 BHLHE73 CSDD1 DPC4 EPAS1 EZF FTZF1 GKLF HIF2A HIF3A KLF4 LIN28 LIN28A MADH2 MADH4 MADR2 MOP2 MOP7 NANOG NR5A1 OCT3 OCT4 OTF3 PASD2 PASD7 PBX1 POU5F1 PRDM14 PRL SALL4 SF1 SMAD2 SMAD4 SOX2 STAT3 ZCCHC1 ZIC3 ZNF203 ZNF206 ZNF797 ZSCAN10	Homo sapiens (human)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Peptidyl-prolyl cis-trans isomerase D Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP5 Prostaglandin E synthase 3 Serine/threonine-protein phosphatase 5	P03372 P07900 P08238 P27361 P28482 P53041 Q02790 Q08752 Q13451 Q15185 Q92731	AIG6 CYP40 CYPD ERK1 ERK2 ESR ESR1 ESR2 ESTRB FKBP4 FKBP5 FKBP51 FKBP52 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB MAPK1 MAPK3 NR3A1 NR3A2 P23 PPID PPP5 PPP5C PRKM1 PRKM2 PRKM3 PTGES3 TEBP	Homo sapiens (human)
Transcriptional and post-translational regulation of MITF-M expression and activity	Adenosine 5'-monophosphoramidase HINT1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 Arginine--tRNA ligase, cytoplasmic Aspartate--tRNA ligase, cytoplasmic Bifunctional glutamate/proline--tRNA ligase CREB-binding protein Cadherin-1 Catenin beta-1 DNA-binding protein inhibitor ID-1 Endothelin receptor type B Endothelin-1 Endothelin-3 Eukaryotic translation elongation factor 1 epsilon-1 Exportin-1 Forkhead box protein D3 Glutamine--tRNA ligase Glycogen synthase kinase-3 beta Histone deacetylase 1 Homeobox protein aristaless-like 3 Isoleucine--tRNA ligase, cytoplasmic Leucine--tRNA ligase, cytoplasmic Lymphoid enhancer-binding factor 1 Lysine--tRNA ligase Mast/stem cell growth factor receptor Kit Melanocortin receptor 3 Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Methionine--tRNA ligase, cytoplasmic Microphthalmia-associated transcription factor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 NAD-dependent protein deacetylase sirtuin-1 POU domain, class 3, transcription factor 2 Paired box protein Pax-3 Pro-opiomelanocortin Protein Wnt-3a RAC-gamma serine/threonine-protein kinase Ribosomal protein S6 kinase alpha-1 T-box transcription factor TBX3 Transcription factor E3 Transcription factor EB Transcription factor EC Transcription factor SOX-10 Transcription factor SOX-2 Transcription factor SOX-9 Zinc finger protein SNAI2 Zinc finger protein ZIC 1	O14948 O14980 O15119 O43324 O43623 O75030 O95076 P01189 P05305 P07814 P10721 P12830 P14138 P14868 P19484 P19532 P20265 P23760 P24530 P27361 P28482 P32245 P33032 P35222 P41134 P41252 P41968 P47897 P48431 P48436 P49773 P49841 P54136 P56192 P56693 P56704 Q01726 Q12904 Q13155 Q13547 Q15046 Q15418 Q15915 Q92793 Q96EB6 Q9P2J5 Q9UJU2 Q9UJU5 Q9Y243	AIMP1 AIMP2 AIMP3 AKT3 ALX3 BHLHB24 BHLHE32 BHLHE33 BHLHE34 BHLHE35 BRN2 CBP CDH1 CDHE CREBBP CRM1 CTNNB CTNNB1 DARS DARS1 EDN1 EDN3 EDNRB EEF1E1 EMAP2 EPRS EPRS1 ERK1 ERK2 ETRB FOXD3 GLNS GSK3B HDAC1 HFH2 HINT HINT1 HUP2 IARS IARS1 ID ID1 JTV1 KARS KARS1 KIAA0070 KIAA1352 KIT LARS LARS1 LEF1 MAPK1 MAPK3 MAPKAPK1A MARS MARS1 MC1R MC3R MC4R MC5R MITF MSHR OCT7 OTF7 P18 PARS PAX3 PKBG PKCI1 POMC POU3F2 PRKCNH1 PRKM1 PRKM2 PRKM3 QARS QARS1 QPRS RARS RARS1 RPD3L1 RPS6KA1 RSK1 SCFR SCYE1 SIR2L1 SIRT1 SLUG SLUGH SNAI2 SOX10 SOX2 SOX9 TBX3 TCFEC TFE3 TFEB TFEC TFECL UVO WNT3A XPO1 ZIC ZIC1 ZNF201	Homo sapiens (human)
SUMOylation of DNA methylation proteins	Chromobox protein homolog 2 Chromobox protein homolog 8 DNA (cytosine-5)-methyltransferase 1 DNA (cytosine-5)-methyltransferase 3A DNA (cytosine-5)-methyltransferase 3B E3 SUMO-protein ligase CBX4 E3 ubiquitin-protein ligase RING1 E3 ubiquitin-protein ligase RING2 Polycomb complex protein BMI-1 Polycomb group RING finger protein 2 Polyhomeotic-like protein 1 Polyhomeotic-like protein 2 Polyhomeotic-like protein 3 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	O00257 P26358 P35226 P35227 P63165 P63279 P78364 Q06587 Q14781 Q8IXK0 Q8NDX5 Q99496 Q9HC52 Q9UBC3 Q9Y6K1	AIM BAP1 BMI1 CBX2 CBX4 CBX8 CXXC9 DING DNMT DNMT1 DNMT3A DNMT3B EDR1 EDR2 EDR3 HIPI3 MEL18 PC3 PCGF2 PCGF4 PH1 PH2 PH3 PHC1 PHC2 PHC3 RC1 RING1 RING1A RING1B RNF1 RNF110 RNF2 RNF51 SMT3C SMT3H3 SUMO1 UBC9 UBCE9 UBE2I UBL1 ZNF144	Homo sapiens (human)
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	Apoptosis regulator BAX Apoptosis-stimulating of p53 protein 1 Apoptosis-stimulating of p53 protein 2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BH3-interacting domain death agonist Bcl-2-binding component 3, isoforms 1/2 CREB-binding protein Cellular tumor antigen p53 Ferroptosis suppressor protein 1 Metalloreductase STEAP3 PRELI domain containing protein 3A PRELI domain-containing protein 1, mitochondrial Phorbol-12-myristate-13-acetate-induced protein 1 Serine-protein kinase ATM TP53-regulated inhibitor of apoptosis 1 Tumor protein 63 Tumor protein p53-inducible nuclear protein 1 Tumor protein p73 Zinc finger protein 420 p53-regulated apoptosis-inducing protein 1	O15350 O43715 O60238 P04637 P55957 Q07812 Q13315 Q13625 Q13794 Q658P3 Q8TAQ5 Q92793 Q96A56 Q96KQ4 Q96N28 Q9BRQ8 Q9BXH1 Q9H3D4 Q9HCN2 Q9Y255	15E1.1 AIFM2 AMID ASPP1 ASPP2 ATM BAX BBC3 BBP BCL2L4 BID BNIP3A BNIP3H BNIP3L C18orf43 CBP CREBBP KET KIAA0771 NIX NOXA P53 P53DINP1 P63 P73 P73H P73L PMAIP1 PPP1R13B PRELI PRELID1 PRELID3A PRG3 PUMA SIP SLMO1 STEAP3 TP53 TP53AIP1 TP53BP2 TP53INP1 TP63 TP73 TP73L TRIAP1 TSAP6 ZNF420	Homo sapiens (human)
Glutathione synthesis and recycling	5-oxoprolinase Cytosolic non-specific dipeptidase Gamma-glutamylcyclotransferase Glutamate--cysteine ligase catalytic subunit Glutamate--cysteine ligase regulatory subunit Glutathione hydrolase 1 proenzyme Glutathione hydrolase 5 proenzyme Glutathione hydrolase 6 Glutathione hydrolase 7 Glutathione synthetase Glutathione-specific gamma-glutamylcyclotransferase 1 Glutathione-specific gamma-glutamylcyclotransferase 2 Putative glutathione hydrolase 3 proenzyme	A6NGU5 O14841 O75223 P19440 P36269 P48506 P48507 P48637 Q6P531 Q8WUX2 Q96KP4 Q9BUX1 Q9UJ14	BOTCH C7orf24 CHAC1 CHAC2 CN2 CNDP2 CPGL CRF21 GCLC GCLM GGCT GGT GGT1 GGT3 GGT3P GGT5 GGT6 GGT7 GGTL3 GGTL5 GGTLA1 GLCL GLCLC GLCLR GSS HEL-S-13 OPLAH PEPA	Homo sapiens (human)
KW2449-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
Signaling by BRAF and RAF1 fusions	14-3-3 protein beta/alpha A-kinase anchor protein 9 AP-3 complex subunit beta-1 Acylglycerol kinase, mitochondrial Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Angiogenic factor with G patch and FHA domains 1 Bcl-2-like protein 11 Beta-arrestin-1 Beta-arrestin-2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epithelial splicing regulatory protein 1 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas H(+)/Cl(-) exchange transporter 6 Integrin alpha-IIb Integrin beta-3 KH domain-containing RNA-binding protein QKI Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 Lysine-specific demethylase 7A MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Myosin phosphatase Rho-interacting protein Phosphatidylethanolamine-binding protein 1 Prelamin-A/C Protein FAM114A2 Protein FAM131B Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase RNA-binding protein FXR1 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Staphylococcal nuclease domain-containing protein 1 Talin-1 Terminal nucleotidyltransferase 4A Trafficking kinesin-binding protein 1 Transcription intermediary factor 1-alpha Type-1 angiotensin II receptor-associated protein Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 UPF0606 protein KIAA1549 Ubiquitin-like modifier-activating enzyme ATG7 Vinculin Zinc finger CCCH-type antiviral protein 1 von Willebrand factor	O00203 O15164 O43252 O43521 O60674 O95352 P01111 P01112 P02545 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P51114 P51797 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q53H12 Q5XG87 Q6NXG1 Q6RW13 Q6VAB6 Q6WCQ1 Q6ZMT4 Q7KZF4 Q7Z2W4 Q7Z5R6 Q86XD5 Q8IVT5 Q8N302 Q8WXI2 Q969H4 Q96PU8 Q99996 Q9HCM3 Q9NRY5 Q9UPV9 Q9UQM7 Q9Y490	ADTB3A AGGF1 AGK AGTRAP AKAP350 AKAP450 AKAP9 AP3B1 APBB1IP APG7L ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 ATG7 ATPSK1 ATRAP BCL2L11 BIM BRAF BRAF1 C5orf3 CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CLCN6 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 ESRP1 F8VWF FAM114A2 FAM131B FGA FGB FGG FN FN1 FXR1 GP2B GP3A GPATC7 GPATCH7 HKQ HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 JHDM1D KDM7 KDM7A KIAA0046 KIAA0051 KIAA0773 KIAA0803 KIAA0864 KIAA0902 KIAA0968 KIAA1027 KIAA1042 KIAA1549 KIAA1718 KREV1 KSR KSR1 KSR2 LMN1 LMNA MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MPRIP MRIP MULK NRAS OIP106 PAPD7 PAPSS PAPSS1 PBP PEBP PEBP1 PKS PKS2 POLS PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 QKI RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RBM35A RHOIP3 RIAM RNF82 SND1 SRC SRC1 TDRD11 TENT4A TIF1 TIF1A TLN TLN1 TRAK1 TRF4 TRIM24 VCL VG5Q VWF YWHAB ZC3HAV1 ZC3HDC2	Homo sapiens (human)
Activation of PKB	3-phosphoinositide-dependent protein kinase 1 Acyl-coenzyme A thioesterase THEM4 RAC-beta serine/threonine-protein kinase Tribbles homolog 3	O15530 P31751 Q5T1C6 Q96RU7	AKT2 C20orf97 CTMP NIPK PDK1 PDPK1 SKIP3 THEM4 TRB3 TRIB3	Homo sapiens (human)
G beta:gamma signalling through CDC42	Cell division control protein 42 homolog Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Rho guanine nucleotide exchange factor 6 Serine/threonine-protein kinase PAK 1	O14610 O14775 O60262 P16520 P50150 P50151 P59768 P60953 P61952 P62873 P62879 P63211 P63215 P63218 Q13153 Q15052 Q9HAV0 Q9P2W3 Q9UBI6 Q9UK08	ARHGEF6 CDC42 COOL2 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 KIAA0006 PAK1 PIXA	Homo sapiens (human)
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	CREB-binding protein Core-binding factor subunit beta Galectin-3 Granulocyte-macrophage colony-stimulating factor Protein kinase C beta type Runt-related transcription factor 1	P04141 P05771 P17931 Q01196 Q13951 Q92793	AML1 CBFA2 CBFB CBP CREBBP CSF2 GMCSF LGALS3 MAC2 PKCB PRKCB PRKCB1 RUNX1	Homo sapiens (human)
Activated point mutants of FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 2	O15520 O43320 O76093 P05230 P08620 P09038 P10767 P11487 P21781 P21802 P31371 Q9GZV9 Q9HCT0 Q9NP95	BEK FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR2 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KGFR KS3 KSAM	Homo sapiens (human)
HDL clearance	Apolipoprotein A-I Cubilin Protein amnionless Vigilin	O60494 P02647 Q00341 Q9BXJ7	AMN APOA1 CUBN HBP HDLBP IFCR VGL	Homo sapiens (human)
SUMOylation of intracellular receptors	Androgen receptor E3 SUMO-protein ligase PIAS1 E3 SUMO-protein ligase PIAS3 E3 SUMO-protein ligase PIAS4 Estrogen receptor Glucocorticoid receptor Histone deacetylase 4 Mineralocorticoid receptor Nuclear receptor ROR-alpha Nuclear receptor subfamily 2 group C member 1 Nuclear receptor subfamily 4 group A member 2 Oxysterols receptor LXR-beta Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma Progesterone receptor Retinoic acid receptor RXR-alpha Retinoic acid receptor alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Steroidogenic factor 1 Thyroid hormone receptor beta Vitamin D3 receptor	O75925 P03372 P04150 P06401 P08235 P10275 P10276 P10828 P11473 P13056 P19793 P35398 P37231 P43354 P55055 P55854 P56524 P61956 P63165 P63279 Q07869 Q13285 Q8N2W9 Q9Y6X2	AD4BP AR DDXBP1 DHTR ERBA2 ESR ESR1 FTZF1 GRL HDAC4 KIAA0288 LXRB MCR MLR NER NOT NR1A2 NR1B1 NR1C1 NR1C3 NR1F1 NR1H2 NR1I1 NR2B1 NR2C1 NR3A1 NR3C1 NR3C2 NR3C3 NR3C4 NR4A2 NR5A1 NURR1 PGR PIAS1 PIAS3 PIAS4 PIASG PPAR PPARA PPARG RARA RORA RXRA RZRA SF1 SMT3A SMT3B SMT3C SMT3H1 SMT3H2 SMT3H3 SUMO1 SUMO2 SUMO3 THR1 THRB TINUR TR2 UBC9 UBCE9 UBE2I UBL1 UNR VDR	Homo sapiens (human)
Common Pathway of Fibrin Clot Formation	Antithrombin-III CD177 antigen Coagulation factor V Coagulation factor VIII Coagulation factor X Coagulation factor XIII A chain Coagulation factor XIII B chain Endothelial protein C receptor Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Glia-derived nexin Heparin cofactor 2 Myeloblastin Plasma serine protease inhibitor Platelet factor 4 variant Platelet factor 4 Proteinase-activated receptor 1 Prothrombin Thrombomodulin Vitamin K-dependent protein C Vitamin K-dependent protein S	P00451 P00488 P00734 P00742 P01008 P02671 P02675 P02679 P02776 P04070 P05154 P05160 P05546 P07093 P07204 P07225 P10720 P12259 P24158 P25116 Q8N6Q3 Q9UNN8	AT3 CD177 CF2R CXCL4 CXCL4V1 EPCR F10 F13A F13A1 F13B F2 F2R F5 F8 F8C FGA FGB FGG HCF2 MBN NB1 PAR1 PCI PF4 PF4V1 PI7 PLANH3 PN1 PROC PROCI PROCR PROS PROS1 PRTN3 PRV1 SCYB4 SCYB4V1 SERPINA5 SERPINC1 SERPIND1 SERPINE2 THBD THRM TR	Homo sapiens (human)
cell division	Kinesin-like protein KIF20A Kinesin-like protein KIF23 Serine/threonine-protein kinase PLK1	O95235 P53350 Q02241	KIF20A KIF23 KNSL5 MKLP1 MKLP2 PLK PLK1 RAB6KIFL	Homo sapiens (human)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(olf) subunit alpha Guanine nucleotide-binding protein G(t) subunit alpha-3	A8MTJ3 O43306 O60266 O60503 O95622 P04899 P08754 P38405 P40145 P51828 P63096 Q08462 Q08828 Q8NFM4	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 GNAI1 GNAI2 GNAI2B GNAI3 GNAL GNAT3 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060	Homo sapiens (human)
Interleukin-4 and Interleukin-13 signaling	72 kDa type IV collagenase Amine oxidase [flavin-containing] A Annexin A1 Apoptosis regulator Bcl-2 B-cell lymphoma 6 protein Baculoviral IAP repeat-containing protein 5 Basic leucine zipper transcriptional factor ATF-like Bcl-2-like protein 1 C-C motif chemokine 22 C-C motif chemokine 2 CCAAT/enhancer-binding protein delta Cellular tumor antigen p53 Coagulation factor XIII A chain Collagen alpha-2(I) chain Cyclin-dependent kinase inhibitor 1 Cytokine receptor common subunit gamma Delta-type opioid receptor Endoplasmin Eotaxin Fascin Fibroblast growth factor 2 Fibronectin Forkhead box protein O1 Forkhead box protein O3 G1/S-specific cyclin-D1 Heat shock cognate 71 kDa protein Heat shock protein HSP 90-alpha Heme oxygenase 1 Hepatocyte growth factor Homeobox protein NANOG Hypoxia-inducible factor 1-alpha Immunoglobulin heavy constant epsilon Immunoglobulin heavy constant gamma 1 Immunoglobulin heavy constant gamma 4 Induced myeloid leukemia cell differentiation protein Mcl-1 Integrin alpha-M Integrin alpha-X Integrin beta-1 Integrin beta-2 Intercellular adhesion molecule 1 Interferon regulatory factor 4 Interleukin-1 alpha Interleukin-1 beta Interleukin-10 Interleukin-12 subunit alpha Interleukin-12 subunit beta Interleukin-13 receptor subunit alpha-1 Interleukin-13 receptor subunit alpha-2 Interleukin-13 Interleukin-17A Interleukin-17F Interleukin-18 Interleukin-23 receptor Interleukin-23 subunit alpha Interleukin-4 receptor subunit alpha Interleukin-4 Interleukin-6 receptor subunit alpha Interleukin-6 Interleukin-8 Interstitial collagenase Laminin subunit alpha-5 Leukemia inhibitory factor Lipopolysaccharide-binding protein Low affinity immunoglobulin epsilon Fc receptor Matrix metalloproteinase-9 Metalloproteinase inhibitor 1 Mu-type opioid receptor Mucin-1 Myc proto-oncogene protein Necdin Neutrophil gelatinase-associated lipocalin Nitric oxide synthase, inducible Non-receptor tyrosine-protein kinase TYK2 Nuclear receptor ROR-alpha Nuclear receptor ROR-gamma Oncostatin-M POU domain, class 2, transcription factor 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Platelet glycoprotein 4 Polyunsaturated fatty acid 5-lipoxygenase Polyunsaturated fatty acid lipoxygenase ALOX15 Pro-opiomelanocortin Prostaglandin G/H synthase 2 Protein c-Fos RAC-alpha serine/threonine-protein kinase Rho-related GTP-binding protein RhoU Serine/threonine-protein kinase pim-1 Serum amyloid A-1 protein Signal transducer and activator of transcription 1-alpha/beta Signal transducer and activator of transcription 3 Signal transducer and activator of transcription 6 Sphingosine 1-phosphate receptor 1 Stromelysin-1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Suppressor of cytokine signaling 5 Trans-acting T-cell-specific transcription factor GATA-3 Transcription factor JunB Transcription factor SOX-2 Transforming growth factor beta-1 proprotein Tumor necrosis factor ligand superfamily member 6 Tumor necrosis factor receptor superfamily member 1B Tumor necrosis factor Twist-related protein 1 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Vascular cell adhesion protein 1 Vascular endothelial growth factor A, long form Vimentin Zinc finger E-box-binding homeobox 1	O00626 O14543 O15230 O15392 O15524 O43524 O60674 O75159 P00488 P01033 P01100 P01106 P01137 P01189 P01375 P01583 P01584 P01854 P01857 P01861 P02751 P03956 P04083 P04637 P05107 P05112 P05231 P05362 P05556 P06734 P07900 P08123 P08253 P08254 P08670 P08887 P09038 P09601 P09917 P0DJI8 P10145 P10415 P11142 P11215 P11309 P13500 P13725 P14210 P14625 P14780 P14859 P15018 P15692 P15941 P16050 P16671 P17275 P18428 P19320 P20333 P20702 P21397 P21453 P22301 P23458 P23771 P24385 P24394 P27986 P29459 P29460 P29597 P31749 P31785 P35225 P35228 P35354 P35372 P35398 P37275 P38936 P40763 P41143 P41182 P42224 P42226 P48023 P48431 P49716 P51449 P51671 P52333 P78552 P80188 Q07817 Q07820 Q12778 Q14116 Q14627 Q15306 Q15672 Q16520 Q16552 Q16658 Q16665 Q5VWK5 Q7L0Q8 Q96PD4 Q99608 Q9H9S0 Q9NPF7	AKT1 ALOX15 ALOX5 ANX1 ANXA1 API4 APRF APT1LG1 AREB6 ARHU BATF BCL1 BCL2 BCL2L BCL2L1 BCL2L3 BCL5 BCL6 BCLX BHLHA38 BHLHE39 BHLHE78 BIRC5 CAP20 CCL11 CCL2 CCL22 CCND1 CD11B CD11C CD18 CD23A CD36 CD95L CDC42L1 CDKN1 CDKN1A CEBPD CHEDG1 CIP1 CIS3 CIS6 CISH5 CISH6 CLEC4J CLG CLG4A CLG4B CLGI COL1A2 COX2 CR3A CTLA8 CXCL8 EDG1 F13A F13A1 FAN1 FASL FASLG FCE2 FCER2 FGF2 FGFB FKHR FKHRL1 FN FN1 FNRB FOS FOXO1 FOXO1A FOXO3 FOXO3A FSCN1 G0S7 G28K GATA3 GP3B GP4 GRB1 GRP94 HGF HIF1A HILDA HMOX1 HNL HO HO1 HPTA HSC70 HSN HSP73 HSP90A HSP90AA1 HSP90B1 HSPA10 HSPA8 HSPC1 HSPC4 HSPCA IAP4 ICAM1 IFNB2 IGEBF IGHE IGHG1 IGHG4 IGIF IL10 IL12A IL12B IL13 IL13R IL13RA IL13RA1 IL13RA2 IL17 IL17A IL17F IL18 IL1A IL1B IL1F1 IL1F2 IL1F4 IL23A IL23R IL2RG IL4 IL4R IL4RA IL6 IL6R IL8 IRF4 ITGAM ITGAX ITGB1 ITGB2 JAK1 JAK1A JAK1B JAK2 JAK3 JUNB KIAA0533 KIAA0671 KIAA1907 LAMA5 LAZ3 LBP LCN2 LIF LOG15 LOG5 LPC1 MAOA MCL1 MCP1 MDA6 MDC MDF2 MFI7 MMP1 MMP2 MMP3 MMP9 MOP1 MOR1 MSK12 MUC1 MUM1 MYC NANOG NC30 NDN NGAL NKSF1 NKSF2 NOS2 NOS2A NR1F1 NR1F3 OCT1 OPRD OPRD1 OPRM1 OSM OTF1 P53 PASD8 PIC1 PIK3R1 PIM1 PKB POMC POU2F1 PRAD1 PTGS2 PUM RAC RHOU RORA RORC RORG RZRA RZRG S1PR1 SAA1 SCYA11 SCYA2 SCYA22 SDI1 SGRF SNL SOCS1 SOCS3 SOCS5 SOX2 SSI1 SSI3 STAT1 STAT3 STAT6 STMY1 TCF8 TGFB TGFB1 TIMP TIMP1 TIP3 TNF TNFA TNFBR TNFR2 TNFRSF1B TNFSF2 TNFSF6 TP53 TRA1 TWIST TWIST1 TYK2 VCAM1 VEGF VEGFA VIM WAF1 WRCH1 ZBTB27 ZEB1 ZNF51	Homo sapiens (human)
Noncanonical activation of NOTCH3	Gamma-secretase subunit APH-1A Gamma-secretase subunit APH-1B Gamma-secretase subunit PEN-2 Neurogenic locus notch homolog protein 3 Nicastrin Presenilin-1 Presenilin-2 Y-box-binding protein 1	P49768 P49810 P67809 Q8WW43 Q92542 Q96BI3 Q9NZ42 Q9UM47	AD3 AD4 APH1A APH1B KIAA0253 NCSTN NOTCH3 NSEP1 PEN2 PS1 PS2 PSEN1 PSEN2 PSENEN PSF PSFL PSNL1 PSNL2 STM2 YB1 YBX1	Homo sapiens (human)
Maturation of nucleoprotein	Glycogen synthase kinase-3 alpha Glycogen synthase kinase-3 beta Nucleoprotein Protein mono-ADP-ribosyltransferase PARP10 Protein mono-ADP-ribosyltransferase PARP14 Protein mono-ADP-ribosyltransferase PARP16 Protein mono-ADP-ribosyltransferase PARP4 Protein mono-ADP-ribosyltransferase PARP6 Protein mono-ADP-ribosyltransferase PARP8 Protein mono-ADP-ribosyltransferase PARP9 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1	P49840 P49841 P59595 P63165 P63279 Q2NL67 Q460N5 Q53GL7 Q8IXQ6 Q8N3A8 Q8N5Y8 Q9UKK3	ADPRTL1 ARTD15 BAL BAL1 BAL2 C15orf30 GSK3A GSK3B KIAA0177 KIAA1268 N PARP10 PARP14 PARP16 PARP4 PARP6 PARP8 PARP9 PARPL SMT3C SMT3H3 SUMO1 UBC9 UBCE9 UBE2I UBL1	Homo sapiens (human)
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)	Sodium-dependent phosphate transport protein 2B	O95436	SLC34A2	Homo sapiens (human)
Inhibition of PKR	Interferon-induced, double-stranded RNA-activated protein kinase Non-structural protein 1	P03496 P19525	EIF2AK2 NS PKR PRKR	Homo sapiens (human)
Amine ligand-binding receptors	G-protein coupled receptor 143 Putative trace amine-associated receptor 3 Trace amine-associated receptor 1 Trace amine-associated receptor 2 Trace amine-associated receptor 5 Trace amine-associated receptor 6 Trace amine-associated receptor 8 Trace amine-associated receptor 9	O14804 P51810 Q969N4 Q96RI8 Q96RI9 Q96RJ0 Q9P1P4 Q9P1P5	GPR102 GPR143 GPR57 GPR58 OA1 PNR TA1 TA3 TA4 TA5 TAAR1 TAAR2 TAAR3 TAAR3P TAAR5 TAAR6 TAAR8 TAAR9 TAR1 TAR3 TAR4 TAR5 TRAR1 TRAR3 TRAR4 TRAR5	Homo sapiens (human)
Activation of BAD and translocation to mitochondria	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta Apoptosis regulator Bcl-2 BH3-interacting domain death agonist Bcl2-associated agonist of cell death Calcineurin subunit B type 1 RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform	P10415 P27348 P31749 P31751 P31946 P31947 P48454 P55957 P61981 P62258 P63098 P63104 Q04917 Q92934 Q9Y243	AKT1 AKT2 AKT3 BAD BBC6 BCL2 BCL2L8 BID CALNA3 CNA2 CNA3 CNB HME1 PKB PKBG PPP3CC PPP3R1 RAC SFN YWHA1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	Homo sapiens (human)

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