GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (10109) Glycans (5831) Glycoproteins (15837) Lectins (297) Pathways (2074)

Displaying entries **276 - 300** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	GlyTouCan ID
Apoptosis induced DNA fragmentation	Caspase-3 DNA fragmentation factor subunit alpha DNA fragmentation factor subunit beta High mobility group protein B1 High mobility group protein B2 Histone H1.0 Histone H1.1 Histone H1.2 Histone H1.3 Histone H1.4 Histone H1.5 Importin subunit alpha-5 Importin subunit beta-1	O00273 O76075 P07305 P09429 P10412 P16401 P16402 P16403 P26583 P42574 P52294 Q02539 Q14974	CAD CASP3 CPP32 DFF1 DFF2 DFF40 DFF45 DFFA DFFB H1-0 H1-1 H1-2 H1-3 H1-4 H1-5 H1F0 H1F1 H1F2 H1F3 H1F4 H1F5 H1FV HIST1H1A HIST1H1B HIST1H1C HIST1H1D HIST1H1E HMG1 HMG2 HMGB1 HMGB2 KPNA1 KPNB1 NTF97 RCH2
TRAF6 mediated IRF7 activation	Antiviral innate immune response receptor RIG-I CREB-binding protein E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Histone acetyltransferase p300 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Interferon alpha-1/13 Interferon alpha-10 Interferon alpha-14 Interferon alpha-16 Interferon alpha-17 Interferon alpha-21 Interferon alpha-2 Interferon alpha-4 Interferon alpha-5 Interferon alpha-6 Interferon alpha-7 Interferon alpha-8 Interferon beta Interferon regulatory factor 3 Interferon regulatory factor 7 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Serine/threonine-protein kinase TBK1 Suppressor of IKBKE 1 TNF receptor-associated factor 2 TNF receptor-associated factor 6 TRAF family member-associated NF-kappa-B activator	O95786 P01562 P01563 P01566 P01567 P01568 P01569 P01570 P01571 P01574 P05013 P05014 P05015 P32881 Q09472 Q12933 Q14164 Q14258 Q14653 Q7Z434 Q8IUD6 Q92793 Q92844 Q92985 Q9BRV8 Q9BYX4 Q9C037 Q9UHD2 Q9Y4K3	CBP CREBBP DDX58 EFP EP300 IFB IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA2A IFNA2B IFNA2C IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB IFNB1 IKBKE IKKE IKKI IPS1 IRF3 IRF7 ITRAF KIAA0151 KIAA1271 MAVS MDA5 NAK P300 RH116 RIGI RNF135 RNF147 RNF85 RNF87 SIKE SIKE1 TANK TBK1 TRAF2 TRAF6 TRAP3 TRIM25 TRIM4 VISA ZNF147
TRAF3 deficiency - HSE	TIR domain-containing adapter molecule 1 TNF receptor-associated factor 3 Toll-like receptor 3	O15455 Q13114 Q8IUC6	CAP-1 CRAF1 PRVTIRB TICAM1 TLR3 TRAF3 TRAFAMN TRIF
Regulation of IGF Activity by IGFBP	72 kDa type IV collagenase Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antitrypsin Alpha-2-HS-glycoprotein Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid beta precursor like protein 2 Amyloid-beta precursor protein Anoctamin-8 Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein E Apolipoprotein L1 BPI fold-containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Calumenin Cathepsin G Ceruloplasmin Chordin-like protein 1 Coagulation factor V Complement C3 Complement C4-A Cystatin-C Cytoskeleton-associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin Extracellular serine/threonine protein kinase FAM20C Fibrillin-1 Fibrinogen alpha chain Fibrinogen gamma chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Follistatin-related protein 3 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Granzyme H Growth arrest-specific protein 6 Heparin cofactor 2 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 2 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Insulin-like growth factor-binding protein 6 Insulin-like growth factor-binding protein 7 Insulin-like growth factor-binding protein complex acid labile subunit Inter-alpha-trypsin inhibitor heavy chain H2 Interleukin-6 Interstitial collagenase Kallikrein-13 Kallikrein-1 Kallikrein-2 Kinectin Kininogen-1 Lactadherin Laminin subunit beta-1 Laminin subunit beta-2 Laminin subunit gamma-1 Latent-transforming growth factor beta-binding protein 1 Macrophage colony-stimulating factor 1 Matrilin-3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane-bound transcription factor site-1 protease Menin Mesothelin Metalloproteinase inhibitor 1 Neurosecretory protein VGF Nucleobindin-1 Osteopontin Palmitoleoyl-protein carboxylesterase NOTUM Pappalysin-1 Pappalysin-2 Patatin-like phospholipase domain-containing protein 2 Plasma alpha-L-fucosidase Plasminogen Proenkephalin-A Proprotein convertase subtilisin/kexin type 9 Prostate-specific antigen Protein Z-dependent protease inhibitor Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein eva-1 homolog A Protein shisa-5 Prothrombin Pseudokinase FAM20A Reticulocalbin-1 SPARC-like protein 1 Sarcoplasmic reticulum histidine-rich calcium-binding protein Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Stanniocalcin-2 Sulfhydryl oxidase 1 Syndecan-2 Tenascin Trans-Golgi network integral membrane protein 2 Transmembrane protein 132A Transport and Golgi organization protein 1 homolog Versican core protein Vitamin K-dependent protein C Wolframin von Willebrand factor A domain-containing protein 1	O00255 O00391 O00622 O14672 O14791 O15232 O15240 O43493 O43852 O76024 O76061 O95084 O95633 O95972 P00450 P00734 P00747 P01008 P01009 P01024 P01033 P01034 P01042 P01210 P01344 P02647 P02649 P02652 P02671 P02679 P02751 P02765 P02768 P02771 P02787 P03956 P04070 P04114 P05019 P05060 P05067 P05231 P05546 P06870 P07237 P07288 P07942 P08253 P08311 P08582 P08833 P09382 P09603 P0C0L4 P10451 P11047 P12259 P12644 P13521 P13611 P14314 P14625 P17936 P18065 P19022 P19823 P20151 P20718 P22692 P23327 P24592 P24593 P24821 P34741 P35555 P35858 P51654 P55268 Q02818 Q06481 Q07065 Q08431 Q12841 Q13103 Q13217 Q13219 Q13316 Q13421 Q14393 Q14515 Q14703 Q14766 Q15084 Q15293 Q16270 Q24JP5 Q5JRA6 Q6P988 Q6PCB0 Q6Q788 Q6UX39 Q86UP2 Q8IXL6 Q8N114 Q8N4F0 Q8NBJ4 Q8NBP7 Q8WXD2 Q96AD5 Q96MK3 Q99217 Q9BRK3 Q9BTY2 Q9BU40 Q9BXP8 Q9GZV9 Q9H8M9 Q9HCE9 Q9NP70 Q9NQ76 Q9NRM1 Q9UK55 Q9UKR3 Q9UM21	A4 AAT AD1 ADAM10 AFP AHSG ALB ALS AMBN AMELX AMG AMGX AMTN ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APOL APOL1 APP APPL2 APS AT3 ATGL AXLLG BDK BMP15 BMP2B BMP4 BNSP BP2 BPIFB2 BPIL1 C20orf184 C3 C4A C9orf155 CALU CCN1 CDH2 CDHN CG1 CGL2 CHGB CHGC CHRDL1 CKAP4 CLG CLG4A CLGI CO4 CP CPAMD1 CPAMD2 CSF1 CSPG2 CST3 CTSG CTSGL2 CYR61 DMP1 DMP4 DNAJC3 DVR4 ENAM ERBA2L ERP5 EVA1A F2 F5 FAM176A FAM20A FAM20C FBN FBN1 FETUA FGA FGF23 FGG FLRG FN FN1 FRP FSTL1 FSTL3 FUCA2 G19P1 GAS6 GDF9B GIG1 GOLM1 GOLPH2 GPC3 GRP94 GZMH HCF2 HCP HPAFP HRC HSP90B1 HSPA5BP1 HSPC4 HSPG1 HXB HYPF IBP1 IBP2 IBP3 IBP4 IBP5 IBP6 IFNB2 IGF1 IGF2 IGFALS IGFBP1 IGFBP10 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 IGHEP2 IL6 ITIH2 KIAA0004 KIAA0091 KIAA0268 KIAA1583 KIAA1623 KLK1 KLK13 KLK2 KLK3 KLKL4 KNG KNG1 KTN1 KUZ LAMB1 LAMB2 LAMC1 LAMS LGALS1 LPLUNC2 LTBP1 MAC25 MADM MAP97 MATN3 MBTPS1 MELTF MEN1 MEPE MFGE8 MFI2 MGAT4A MIA3 MMP1 MMP2 MPF MSLN MXRA8 NARC1 NCAD NOTUM NRLN1 NUC NUCB1 OCI5 OPN P4HB P5 P58IPK PAPPA PAPPA2 PCSK9 PDI PDIA1 PDIA6 PENK PI PLAC3 PLG PNPLA2 PO4DB PRKCSH PRKRI PROC PRSS23 PSF QSCN6 QSOX1 RAP3 RCN RCN1 S1P SCG1 SCG2 SCG3 SCOTIN SDC2 SERPINA1 SERPINA10 SERPINC1 SERPIND1 SHISA5 SKI1 SPARCL1 SPP1 SPP2 SPP24 STC2 TANGO TF TGN46 TGN51 TGOLN2 TIMP TIMP1 TMEM132A TMEM166 TMEM16H TNC TRA1 TXNDC7 VCAN VGF VWA1 WFS1 ZPI ZSIG13
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	A-kinase anchor protein 5 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 Glucagon-like peptide 1 receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Potassium voltage-gated channel subfamily B member 1 Potassium voltage-gated channel subfamily S member 3 Pro-glucagon Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Voltage-gated potassium channel KCNC2 Voltage-gated potassium channel regulatory subunit KCNG2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O14610 O14775 O43306 O60262 O95398 O95622 P01275 P10644 P13861 P16520 P17612 P22612 P22694 P24588 P31321 P31323 P40145 P43220 P46940 P50150 P50151 P59768 P61952 P62834 P62873 P62879 P63092 P63211 P63215 P63218 Q14571 Q14573 Q14643 Q14721 Q5JWF2 Q8WZA2 Q96PR1 Q9BQ31 Q9HAV0 Q9P2W3 Q9UBI6 Q9UJ96 Q9UK08	ADCY5 ADCY6 ADCY8 AKAP5 AKAP79 CGEF1 CGEF2 EPAC EPAC1 EPAC2 GCG GLP1R GNAS GNAS1 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP INSP3R1 IQGAP1 ITPR1 ITPR2 ITPR3 KCNB1 KCNC2 KCNF2 KCNG2 KCNS3 KIAA0051 KIAA0422 KREV1 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B RAP1A RAPGEF3 RAPGEF4 TSE1
Surfactant metabolism	Adenosine deaminase 2 Adenosine receptor A2a Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Cytokine receptor common subunit beta Cytoskeleton-associated protein 4 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha LIM and cysteine-rich domains protein 1 Napsin-A P2Y purinoceptor 2 Palmitoyltransferase ZDHHC2 Pepsin A-3 Pepsin A-4 Pepsin A-5 Phospholipid-transporting ATPase ABCA3 Pro-cathepsin H Pulmonary surfactant-associated protein A1 Pulmonary surfactant-associated protein A2 Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein D Scavenger receptor cysteine-rich domain-containing protein DMBT1 Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Surfactant protein C Surfactant-associated protein 3 Thyroid transcription factor 1-associated protein 26 Transcription factor GATA-6 Transcription termination factor 1	O95436 O96009 P07988 P08913 P09668 P0C7M3 P0DJD7 P0DJD8 P0DJD9 P11686 P15509 P18825 P29274 P29275 P32927 P35247 P41231 Q06495 Q07065 Q15361 Q8IWL1 Q8IWL2 Q8IZF2 Q92908 Q99758 Q9NZK5 Q9NZU5 Q9P031 Q9UGM3 Q9UIJ5	ABC3 ABCA3 ADA2 ADGF ADGRF5 ADORA2 ADORA2A ADORA2B ADRA2A ADRA2C ADRA2L2 ADRA2R ADRA2RL2 ADRAR BR22 CCDC59 CECR1 CKAP4 COLEC4 COLEC5 COLEC7 CPSB CSF2R CSF2RA CSF2RB CSF2RY CTSH DMBT1 GATA6 GP340 GPR116 IDGFL IL3RB IL5RB KIAA0758 LMCD1 NAP1 NAPA NAPSA NPT2 P2RU1 P2RY2 PGA3 PGA4 PGA5 PSAP PSPD REAM REC SFTA3 SFTP1 SFTP2 SFTP3 SFTP4 SFTPA SFTPA1 SFTPA1B SFTPA2 SFTPA2B SFTPB SFTPC SFTPD SFTPH SLC17A2 SLC34A1 SLC34A2 TAP26 TTF1 ZDHHC2 ZNF372
Signaling by high-kinase activity BRAF mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Phosphatidylethanolamine-binding protein 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Vinculin von Willebrand factor	P01111 P01112 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q6VAB6 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 KIAA0051 KIAA0902 KIAA1027 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 NRAS PBP PEBP PEBP1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RIAM SRC SRC1 TLN TLN1 VCL VWF YWHAB
SHC-mediated cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 GTPase HRas GTPase NRas Son of sevenless homolog 1	O15520 O43320 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P21781 P31371 Q07889 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 NRAS SOS1
Hedgehog 'off' state	Adenylate cyclase type 10 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Centriole and centriolar satellite protein OFD1 Cytoplasmic dynein 2 heavy chain 1 G-protein coupled receptor 161 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Intraflagellar transport protein 122 homolog Intraflagellar transport protein 140 homolog Intraflagellar transport protein 172 homolog Intraflagellar transport protein 52 homolog Intraflagellar transport protein 57 homolog Intraflagellar transport protein 88 homolog Kinesin-like protein KIF3A Kinesin-like protein KIF7 Protein fantom Protein fuzzy homolog Protein inturned Protein patched homolog 1 Protein smoothened Suppressor of fused homolog Tectonic-like complex member MKS1 Tetratricopeptide repeat protein 21B Transcriptional activator GLI3 Tubby-related protein 3 WD repeat-containing protein 19 WD repeat-containing protein 35 Zinc finger protein GLI1 Zinc finger protein GLI2 cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O75386 O75665 O95622 P08151 P10070 P10071 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 P63092 Q08462 Q08828 Q13099 Q13635 Q2M1P5 Q5JWF2 Q68CZ1 Q7Z4L5 Q8N6U8 Q8NCM8 Q8NEZ3 Q8NFM4 Q96PN6 Q96RY7 Q99835 Q9BT04 Q9HBG6 Q9NWB7 Q9NXB0 Q9P2L0 Q9UG01 Q9ULD6 Q9UMX1 Q9Y366 Q9Y496	ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 C20orf9 CXorf5 DERP8 DHC1B DHC2 DNCH2 DYH1B DYNC2H1 ESRRBL1 FTM FUZ FY GLI GLI1 GLI2 GLI3 GNAS GNAS1 GPR161 GSP HIPPI IFT121 IFT122 IFT139 IFT140 IFT144 IFT172 IFT52 IFT57 IFT88 INTU KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA0590 KIAA1005 KIAA1060 KIAA1179 KIAA1284 KIAA1336 KIAA1638 KIAA1992 KIAA1997 KIF3 KIF3A KIF7 MKS1 NGD5 NPHP8 OFD1 PDZD6 PDZK6 PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B PTCH PTCH1 RPGRIP1L SAC SMO SMOH SPG SUFU TG737 THP TSE1 TTC10 TTC21B TUBL3 TULP3 WDR10 WDR140 WDR19 WDR35 WDTC2
Paradoxical activation of RAF signaling by kinase inactive BRAF	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB
Type II Na+/Pi cotransporters	Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Sodium-dependent phosphate transport protein 2C	O95436 Q06495 Q8N130	NPT2 NPT2C NPTIIC SLC17A2 SLC34A1 SLC34A2 SLC34A3
G alpha (z) signalling events	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Guanine nucleotide-binding protein G(t) subunit alpha-3 Guanine nucleotide-binding protein G(z) subunit alpha Guanine nucleotide-binding protein subunit beta-4 Guanine nucleotide-binding protein subunit beta-5 Protein kinase C alpha type Protein kinase C beta type Protein kinase C delta type Protein kinase C epsilon type Protein kinase C eta type Protein kinase C gamma type Protein kinase C theta type Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 Regulator of G-protein signaling 19 Regulator of G-protein signaling 20 Regulator of G-protein signaling 4 Regulator of G-protein signaling protein-like	A5PLK6 A8MTJ3 O14610 O14775 O15492 O43306 O60262 O60266 O60503 O76081 O95622 P04899 P05129 P05771 P08754 P08913 P16520 P17252 P18089 P18825 P19086 P24723 P40145 P49795 P49798 P50150 P50151 P51828 P59768 P61952 P62873 P62879 P63092 P63096 P63211 P63215 P63218 Q02156 Q04759 Q05655 Q08462 Q08828 Q5JWF2 Q8NFM4 Q9HAV0 Q9P2W3 Q9UBI6 Q9UGC6 Q9UK08	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRA2A ADRA2B ADRA2C ADRA2L1 ADRA2L2 ADRA2R ADRA2RL1 ADRA2RL2 ADRAR GAIP GNAI1 GNAI2 GNAI2B GNAI3 GNAI3IP GNAS GNAS1 GNAT3 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNG9 GNGT1 GNGT10 GNGT11 GNGT2 GNGT3 GNGT4 GNGT5 GNGT7 GNGT8 GNGT9 GSP KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 PKCA PKCB PKCD PKCE PKCG PKCL PRKACA PRKCA PRKCB PRKCB1 PRKCD PRKCE PRKCG PRKCH PRKCL PRKCQ PRKCT RGS16 RGS17 RGS19 RGS20 RGS4 RGSL RGSL1 RGSL2 RGSR RGSZ1 RGSZ2 ZGAP1
RPIA deficiency: failed conversion of R5P to RU5P	Ribose-5-phosphate isomerase	P49247	RPI RPIA
Formation of the nephric duct	Bone morphogenetic protein 4 Catenin beta-1 DNA-binding protein inhibitor ID-4 Fibroblast growth factor 2 Histone-lysine N-methyltransferase MECOM Homeobox protein EMX2 Homeobox protein Hox-A6 Homeobox protein Hox-B4 LIM/homeobox protein Lhx1 Nephronectin Paired box protein Pax-2 Paired box protein Pax-8 Placenta-specific gene 8 protein Protein odd-skipped-related 1 Proto-oncogene tyrosine-protein kinase receptor Ret Protocadherin-19 Trans-acting T-cell-specific transcription factor GATA-3 WAP four-disulfide core domain protein 2	P07949 P09038 P12644 P17483 P23771 P31267 P35222 P47928 P48742 Q02962 Q03112 Q04743 Q06710 Q14508 Q6UXI9 Q8TAB3 Q8TAX0 Q9NZF1	BHLHB27 BMP2B BMP4 CDHF12 CDHR16 CTNNB CTNNB1 DVR4 EGFL6L EMX2 EVI1 FGF2 FGFB GATA3 HE4 HOX1B HOX2F HOXA6 HOXB4 ID4 KIAA1313 LHX1 LIM-1 LIM1 MDS1 MECOM NPNT ODD OSR1 PAX2 PAX8 PCDH19 PLAC8 POEM PRDM3 PTC RET WAP5 WFDC2
Essential fructosuria	Ketohexokinase	P50053	KHK
Synthesis of bile acids and bile salts via 24-hydroxycholesterol	24-hydroxycholesterol 7-alpha-hydroxylase 3 beta-hydroxysteroid dehydrogenase type 7 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase Aldo-keto reductase family 1 member C1 Aldo-keto reductase family 1 member C2 Aldo-keto reductase family 1 member C3 Aldo-keto reductase family 1 member C4 Aldo-keto reductase family 1 member D1 Alpha-methylacyl-CoA racemase Cholesterol 24-hydroxylase Long-chain fatty acid transport protein 2 Long-chain fatty acid transport protein 5 Sterol 26-hydroxylase, mitochondrial	O14975 P17516 P42330 P51857 P52895 Q02318 Q04828 Q9H2F3 Q9NYL5 Q9UHK6 Q9UNU6 Q9Y2P5 Q9Y6A2	ACSB ACSVL1 ACSVL6 AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 AMACR CHDR CYP12 CYP27 CYP27A1 CYP39A1 CYP46 CYP46A1 CYP8B1 DDH DDH1 DDH2 FACVL1 FACVL3 FATP2 FATP5 HSD17B5 HSD3B7 KIAA0119 PGFS SLC27A2 SLC27A5 SRD5B1 VLACS
LXRs regulate gene expression linked to triglyceride lipolysis in adipose	Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Perilipin-1 Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta	O60240 P19793 P28702 P55055 Q13133	LXRA LXRB NER NR1H2 NR1H3 NR2B1 NR2B2 PERI PLIN PLIN1 RXRA RXRB UNR
Mtb iron assimilation by chelation	Bacterioferritin BfrA Bacterioferritin BfrB Lactotransferrin Mycobactin import ATP-binding/permease protein IrtA Mycobactin import ATP-binding/permease protein IrtB Uncharacterized protein Rv2895c	P02788 P9WL31 P9WNE5 P9WPQ9 P9WQJ7 P9WQJ9	GIG12 LF LTF Rv2895c bfr bfrA bfrB ftn irtA irtB
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	DNA polymerase beta DNA repair nuclease/redox regulator APEX1	P06746 P27695	APE APE1 APEX APEX1 APX HAP1 POLB REF1
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	Adenosine 5'-monophosphoramidase HINT1 Catenin beta-1 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 2A G1/S-specific cyclin-D1 G2/mitotic-specific cyclin-B1 Hepatocyte growth factor receptor Histone deacetylase 1 Lymphoid enhancer-binding factor 1 Paired amphipathic helix protein Sin3a Serine/threonine-protein kinase PLK1 T-box transcription factor TBX2 Transcription factor 7-like 1 Transcription factor 7-like 2 Transcription factor 7	P08581 P14635 P24385 P24941 P35222 P36402 P38936 P42771 P49773 P53350 Q13207 Q13547 Q96ST3 Q9HCS4 Q9NQB0 Q9UJU2	BCL1 CAP20 CCNB CCNB1 CCND1 CDK2 CDKN1 CDKN1A CDKN2 CDKN2A CIP1 CTNNB CTNNB1 HDAC1 HINT HINT1 LEF1 MDA6 MET MTS1 PIC1 PKCI1 PLK PLK1 PRAD1 PRKCNH1 RPD3L1 SDI1 SIN3A TBX2 TCF1 TCF3 TCF4 TCF7 TCF7L1 TCF7L2 WAF1
Disassembly of the destruction complex and recruitment of AXIN to the membrane	APC membrane recruitment protein 1 Adenomatous polyposis coli protein Axin-1 Casein kinase I isoform alpha Casein kinase I isoform gamma-2 Catenin beta-1 Caveolin-1 Frizzled-1 Frizzled-2 Frizzled-5 GSK-3-binding protein FRAT2 Glycogen synthase kinase-3 beta Low-density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein 6 Protein Wnt-3a Protein Wnt-8a Protein Wnt-8b Proto-oncogene FRAT1 Proto-oncogene Wnt-1 Segment polarity protein dishevelled homolog DVL-1 Segment polarity protein dishevelled homolog DVL-2 Segment polarity protein dishevelled homolog DVL-3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	O14640 O14641 O15169 O75197 O75474 O75581 P04628 P25054 P30153 P30154 P35222 P48729 P49841 P56704 P62714 P67775 P78368 Q03135 Q13362 Q13467 Q14332 Q14738 Q15172 Q15173 Q16537 Q5JTC6 Q92837 Q92997 Q93098 Q9H1J5 Q9UP38	AMER1 APC AXIN AXIN1 C2orf31 CAV CAV1 CK1G2 CSNK1A1 CSNK1G2 CTNNB CTNNB1 DP2.5 DVL1 DVL2 DVL3 FAM123B FRAT1 FRAT2 FZD1 FZD2 FZD5 GSK3B INT1 KIAA0044 KIAA0208 LR3 LRP5 LRP6 LRP7 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E WNT1 WNT3A WNT8A WNT8B WNT8D WTX
The fatty acid cycling model	Brain mitochondrial carrier protein 1 Dicarboxylate carrier SLC25A8 Mitochondrial brown fat uncoupling protein 1 Mitochondrial uncoupling protein 4 Putative mitochondrial transporter UCP3	O95258 O95847 P25874 P55851 P55916	BMCP1 SLC25A14 SLC25A27 SLC25A7 SLC25A8 SLC25A9 UCP UCP1 UCP2 UCP3 UCP4 UCP5
Regulation of lipid metabolism by PPARalpha	3'-5' exoribonuclease HELZ2 CREB-binding protein Chromodomain-helicase-DNA-binding protein 9 F-box-like/WD repeat-containing protein TBL1X F-box-like/WD repeat-containing protein TBL1XR1 Fatty acid-binding protein, liver Histone deacetylase 3 Histone-arginine methyltransferase CARM1 Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor coactivator 1 Nuclear receptor coactivator 2 Nuclear receptor coactivator 6 Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Paired amphipathic helix protein Sin3a Peroxisome proliferator-activated receptor alpha Retinoic acid receptor RXR-alpha SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 Trimethylguanosine synthase	O15379 O60907 O75376 P07148 P19793 Q07869 Q14686 Q15596 Q15648 Q15788 Q3L8U1 Q6STE5 Q86X55 Q92793 Q96RS0 Q96ST3 Q9BYK8 Q9BZK7 Q9Y618	AIB3 ARC205 BAF60C BHLHE74 BHLHE75 CARM1 CBP CHD9 CREBBP CRSP1 CRSP200 CTG26 DRIP205 DRIP230 FABP1 FABPL HCA137 HDAC3 HELZ2 IRA1 KIAA0181 KIAA0308 KIAA1047 KIAA1769 KISH2 MED1 NCOA1 NCOA2 NCOA6 NCOA6IP NCOR1 NCOR2 NR1C1 NR2B1 PBP PIMT PPAR PPARA PPARBP PPARGBP PRIC285 PRIC320 PRMT4 RAP250 RB18A RXRA SIN3A SMARCD3 SRC1 SRC2 TBL1 TBL1X TBL1XR1 TBLR1 TGS1 TIF2 TRAP220 TRBP TRIP2
SHC1 events in ERBB2 signaling	Epidermal growth factor receptor GTPase HRas GTPase NRas Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Protein kinase C alpha type Protein kinase C delta type Protein kinase C epsilon type Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 12	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P17252 P29353 P35070 P56975 Q02156 Q02297 Q05209 Q05655 Q07889 Q8WWG1 Q99075	BTC DTR DTS EGF EGFR ERBB ERBB1 ERBB2 EREG GGF HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PKCA PKCD PKCE PRKACA PRKCA PRKCD PRKCE PTPN12 SHC SHC1 SHCA SMDF SOS1
N-glycan trimming and elongation in the cis-Golgi	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Glycoprotein endo-alpha-1,2-mannosidase	P26572 Q5SRI9	GGNT1 GLCT1 GLYT1 MANEA MGAT MGAT1	G58161NS

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