RUNX2 regulates genes involved in cell migration
|
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- AKT1
- AKT2
- AKT3
- CBFB
- FNRA
- ITGA5
- ITGBL1
- MMP13
- OSCP
- PKB
- PKBG
- RAC
- TIED
|
Homo sapiens (human)
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CTLA4 inhibitory signaling
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- AKT1
- AKT2
- AKT3
- CD152
- CD28LG
- CD28LG1
- CD28LG2
- CD80
- CD86
- CTLA4
- FYN
- JTK8
- KIAA0044
- LAB7
- LCK
- LYN
- PKB
- PKBG
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PTP2C
- PTPN11
- RAC
- SHPTP2
- YES
- YES1
|
Homo sapiens (human)
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Downregulation of ERBB2:ERBB3 signaling
|
|
|
- AKT1
- AKT2
- AKT3
- ERBB2
- FLRF
- GGF
- HER2
- HGL
- HRGA
- KIAA0055
- MLN19
- NDF
- NEU
- NGL
- NRDP1
- NRG1
- NRG2
- NTAK
- PKB
- PKBG
- RAC
- RNF41
- RPS27A
- SMDF
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBPY
- USP8
|
Homo sapiens (human)
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AKT-mediated inactivation of FOXO1A
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- AKT1
- AKT2
- AKT3
- FKHR
- FOXO1
- FOXO1A
- PKB
- PKBG
- RAC
|
Homo sapiens (human)
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Deactivation of the beta-catenin transactivating complex
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- AKT1
- AKT2
- ALR
- APC
- API3
- ARB1
- ASH2L
- ASH2L1
- BCL9
- BCL9L
- BIRC4
- BTRC
- BTRCP
- C22orf2
- CBY
- CBY1
- CHD8
- CRM1
- CTBP
- CTBP1
- CTNNB
- CTNNB1
- CTNNBIP1
- DLNB11
- DP2.5
- FBW1A
- FBXW1A
- GRG4
- HDAC1
- HELSNF1
- IAP3
- ICAT
- KIAA1261
- KIAA1547
- KIAA1564
- KMT2D
- LEF1
- MEN1
- MLL2
- MLL4
- PGEA1
- PKB
- PYGO1
- PYGO2
- RAC
- RBBP5
- RBQ3
- RPD3L1
- RPS27A
- SCG2
- SOX13
- SOX17
- SOX2
- SOX3
- SOX4
- SOX6
- SOX7
- SOX9
- SRY
- TCF1
- TCF3
- TCF4
- TCF7
- TCF7L1
- TCF7L2
- TDF
- TLE1
- TLE2
- TLE3
- TLE4
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- XIAP
- XPO1
- YWHAZ
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Homo sapiens (human)
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Translocation of SLC2A4 (GLUT4) to the plasma membrane
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- AKT1
- AKT2
- AMPK
- AMPK2
- AMPKG3
- ARHQ
- AS160
- ASPL
- ASPSCR1
- C20orf74
- C2CD5
- CALM
- CALM1
- CAM
- CAM1
- CDP138
- EXO70
- EXOC1
- EXOC2
- EXOC3
- EXOC4
- EXOC5
- EXOC6
- EXOC7
- EXOC8
- GLUT4
- HME1
- KIAA0359
- KIAA0528
- KIAA0603
- KIAA1067
- KIAA1108
- KIAA1219
- KIAA1272
- KIAA1699
- KIF3
- KIF3A
- KIF3AP
- KIF3B
- KIFAP3
- LNPEP
- MEL
- MYH12
- MYH9
- MYO1C
- MYO5A
- OTASE
- PKB
- PRKAA2
- PRKAB1
- PRKAB2
- PRKAG1
- PRKAG2
- PRKAG3
- RAB10
- RAB11
- RAB11A
- RAB13
- RAB14
- RAB4
- RAB4A
- RAB8
- RAB8A
- RAC
- RAC1
- RAL
- RALA
- RALGAPA2
- RALGAPB
- RASL7A
- RCC17
- RHOQ
- SEC10
- SEC10L1
- SEC15A
- SEC15L
- SEC15L1
- SEC3
- SEC3L1
- SEC5
- SEC5L1
- SEC6
- SEC6L1
- SEC8
- SEC8L1
- SFN
- SLC2A4
- SMAP
- SNAP23
- STX4
- STX4A
- STXBP3
- SYB2
- TBC1D1
- TBC1D4
- TC10
- TC25
- TUG
- UBXD9
- UBXN9
- VAMP2
- YWHA1
- YWHAB
- YWHAE
- YWHAG
- YWHAH
- YWHAQ
- YWHAZ
|
Homo sapiens (human)
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|
Interleukin-4 and Interleukin-13 signaling
|
|
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- AKT1
- ALOX15
- ALOX5
- ANX1
- ANXA1
- API4
- APRF
- APT1LG1
- AREB6
- ARHU
- BATF
- BCL1
- BCL2
- BCL2L
- BCL2L1
- BCL2L3
- BCL5
- BCL6
- BCLX
- BHLHA38
- BHLHE39
- BHLHE78
- BIRC5
- CAP20
- CCL11
- CCL2
- CCL22
- CCND1
- CD11B
- CD11C
- CD18
- CD23A
- CD36
- CD95L
- CDC42L1
- CDKN1
- CDKN1A
- CEBPD
- CHEDG1
- CIP1
- CIS3
- CIS6
- CISH5
- CISH6
- CLEC4J
- CLG
- CLG4A
- CLG4B
- CLGI
- COL1A2
- COX2
- CR3A
- CTLA8
- CXCL8
- EDG1
- F13A
- F13A1
- FAN1
- FASL
- FASLG
- FCE2
- FCER2
- FGF2
- FGFB
- FKHR
- FKHRL1
- FN
- FN1
- FNRB
- FOS
- FOXO1
- FOXO1A
- FOXO3
- FOXO3A
- FSCN1
- G0S7
- G28K
- GATA3
- GP3B
- GP4
- GRB1
- GRP94
- HGF
- HIF1A
- HILDA
- HMOX1
- HNL
- HO
- HO1
- HPTA
- HSC70
- HSN
- HSP73
- HSP90A
- HSP90AA1
- HSP90B1
- HSPA10
- HSPA8
- HSPC1
- HSPC4
- HSPCA
- IAP4
- ICAM1
- IFNB2
- IGEBF
- IGHE
- IGHG1
- IGHG4
- IGIF
- IL10
- IL12A
- IL12B
- IL13
- IL13R
- IL13RA
- IL13RA1
- IL13RA2
- IL17
- IL17A
- IL17F
- IL18
- IL1A
- IL1B
- IL1F1
- IL1F2
- IL1F4
- IL23A
- IL23R
- IL2RG
- IL4
- IL4R
- IL4RA
- IL6
- IL6R
- IL8
- IRF4
- ITGAM
- ITGAX
- ITGB1
- ITGB2
- JAK1
- JAK1A
- JAK1B
- JAK2
- JAK3
- JUNB
- KIAA0533
- KIAA0671
- KIAA1907
- LAMA5
- LAZ3
- LBP
- LCN2
- LIF
- LOG15
- LOG5
- LPC1
- MAOA
- MCL1
- MCP1
- MDA6
- MDC
- MDF2
- MFI7
- MMP1
- MMP2
- MMP3
- MMP9
- MOP1
- MOR1
- MSK12
- MUC1
- MUM1
- MYC
- NANOG
- NC30
- NDN
- NGAL
- NKSF1
- NKSF2
- NOS2
- NOS2A
- NR1F1
- NR1F3
- OCT1
- OPRD
- OPRD1
- OPRM1
- OSM
- OTF1
- P53
- PASD8
- PIC1
- PIK3R1
- PIM1
- PKB
- POMC
- POU2F1
- PRAD1
- PTGS2
- PUM
- RAC
- RHOU
- RORA
- RORC
- RORG
- RZRA
- RZRG
- S1PR1
- SAA1
- SCYA11
- SCYA2
- SCYA22
- SDI1
- SGRF
- SNL
- SOCS1
- SOCS3
- SOCS5
- SOX2
- SSI1
- SSI3
- STAT1
- STAT3
- STAT6
- STMY1
- TCF8
- TGFB
- TGFB1
- TIMP
- TIMP1
- TIP3
- TNF
- TNFA
- TNFBR
- TNFR2
- TNFRSF1B
- TNFSF2
- TNFSF6
- TP53
- TRA1
- TWIST
- TWIST1
- TYK2
- VCAM1
- VEGF
- VEGFA
- VIM
- WAF1
- WRCH1
- ZBTB27
- ZEB1
- ZNF51
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Homo sapiens (human)
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|
Integrin signaling
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|
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- AKT1
- APBB1IP
- CDC25L
- CGEF1
- CGEF2
- CSK
- EPAC
- EPAC1
- EPAC2
- F8VWF
- FAK
- FAK1
- FGA
- FGB
- FGG
- FN
- FN1
- GP2B
- GP3A
- ITGA2B
- ITGAB
- ITGB3
- KIAA1027
- KREV1
- MCG7
- PDK1
- PDPK1
- PKB
- PREL1
- PTK2
- PTP1B
- PTPN1
- RAC
- RAP1A
- RAP1B
- RAPGEF3
- RAPGEF4
- RARP1
- RASGRP
- RASGRP1
- RASGRP2
- RIAM
- SHC
- SHC1
- SHCA
- SRC
- SRC1
- SYK
- TLN
- TLN1
- VWF
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Homo sapiens (human)
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eNOS activation
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- AKT1
- APT1
- CALM
- CALM1
- CAM
- CAM1
- CAV
- CAV1
- CYB5B
- CYB5M
- CYGB
- DDAH
- DDAH1
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- LPL1
- LYPLA1
- NMT
- NMT1
- NMT2
- NOS3
- OMB5
- PKB
- RAC
- SPR
- STAP
- ZDHHC21
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Homo sapiens (human)
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PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
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- AKT1
- ARAP1
- BRK
- CBL
- CBL2
- CENTD2
- DOK1
- KIAA0782
- PKB
- PTK6
- RAC
- RNF55
- RPS27A
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Homo sapiens (human)
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PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
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- AKT1
- AREG
- AREGB
- ARHG
- BCAP
- BDNF
- BTC
- C9orf26
- CD135
- CD19
- CD28
- CD28LG
- CD28LG1
- CD28LG2
- CD80
- CD86
- DER4
- DIF2
- DTR
- DTS
- EGF
- EGFR
- EPGN
- ERBB
- ERBB1
- ERBB2
- EREG
- ERK1
- ERK2
- ESR
- ESR1
- ESR2
- ESTRB
- FGF1
- FGF10
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF22
- FGF23
- FGF3
- FGF4
- FGF6
- FGF7
- FGF9
- FGFA
- FGFB
- FGFR4
- FLK2
- FLT3
- FLT3LG
- FRS2
- FYN
- GAB1
- GAB2
- GGF
- GRB1
- HBEGF
- HEGFL
- HER1
- HER2
- HGF
- HGL
- HPTA
- HRGA
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- IER3
- IEX1
- IL1F11
- IL1RL1
- IL33
- INS
- INSR
- INT2
- IRAK
- IRAK1
- IRAK4
- IRS1
- IRS2
- JTK2
- KGF
- KIAA0044
- KIAA0571
- KIAA0589
- KIT
- KLB
- KS3
- LAB7
- LCK
- MAPK1
- MAPK3
- MET
- MLN19
- MYD88
- NDF
- NEU
- NFHEV
- NGL
- NR3A1
- NR3A2
- NRG1
- NRG2
- NRG3
- NRG4
- NTAK
- NTF3
- NTF4
- NTF5
- NTRK2
- NTRK3
- PDGF2
- PDGFB
- PDGFR
- PDGFR1
- PDGFR2
- PDGFRA
- PDGFRB
- PI5P4KA
- PIK3AP1
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PIK3R3
- PIP4K2A
- PIP4K2B
- PIP4K2C
- PIP5K1A
- PIP5K1B
- PIP5K1C
- PIP5K2
- PIP5K2A
- PIP5K2B
- PIP5K2C
- PKB
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PRG1
- PRKM1
- PRKM2
- PRKM3
- PTP2C
- PTPN11
- RAC
- RAC1
- RAC2
- RHEPDGFRA
- RHOG
- RNF85
- SCFR
- SDGF
- SHPTP2
- SIS
- SMDF
- SRC
- SRC1
- ST2
- STK1
- STM7
- STRN
- T1
- TC25
- TCRIM
- TGFA
- TKF
- TRAF6
- TRAT1
- TRKB
- TRKC
- VAV
- VAV1
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Homo sapiens (human)
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|
Extra-nuclear estrogen signaling
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|
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- AKT1
- AREG
- AREGB
- BTC
- C9orf108
- C9orf47
- CALM
- CALM1
- CAM
- CAM1
- CAV
- CAV1
- CAV2
- CLG4A
- CLG4B
- DTR
- DTS
- EDG3
- EGF
- EGFR
- EPGN
- ERBB
- ERBB1
- EREG
- ESR
- ESR1
- ESR2
- ESTRB
- FAK
- FAK1
- GNAI1
- GNAI2
- GNAI2B
- GNAI3
- GNAT3
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNG9
- GNGT1
- GNGT10
- GNGT11
- GNGT2
- GNGT3
- GNGT4
- GNGT5
- GNGT7
- GNGT8
- GNGT9
- GRB1
- HBEGF
- HEGFL
- HER1
- HMT2
- HRMT1L2
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- IGF1R
- IR1B4
- MMP2
- MMP3
- MMP7
- MMP9
- MPSL1
- NOS3
- NR3A1
- NR3A2
- PIK3CA
- PIK3R1
- PIK3R2
- PIK3R3
- PKB
- PRMT1
- PTK2
- PUMP1
- RAC
- S1PR3
- SDGF
- SK1
- SPHK
- SPHK1
- SPK
- SRC
- SRC1
- STMY1
- STRN
- TGFA
- ZDHHC21
- ZDHHC7
|
Homo sapiens (human)
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|
Mitochondrial unfolded protein response (UPRmt)
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|
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- AKT1
- ATF5
- ATFX
- CAT
- DEF5
- DEFA5
- DNAJ2
- DNAJA1
- ESR
- ESR1
- FKHRL1
- FOXO3
- FOXO3A
- GRP75
- HDJ2
- HSF1
- HSJ2
- HSP60
- HSP72
- HSPA1
- HSPA1A
- HSPA1B
- HSPA9
- HSPA9B
- HSPD1
- HSPE1
- HSPF4
- HSTF1
- HSX70
- HTRA2
- LONP1
- NR3A1
- NRF1
- OMI
- PKB
- PRSS15
- PRSS25
- RAC
- SIR2L3
- SIRT3
- SOD2
- mt-HSP70
|
Homo sapiens (human)
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|
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
|
|
|
- AKT1
- BERG36
- BRF1
- CML28
- CSL4
- DCP1A
- DCP2
- DIS3
- ERF1
- EXOSC1
- EXOSC2
- EXOSC3
- EXOSC4
- EXOSC5
- EXOSC6
- EXOSC7
- EXOSC8
- EXOSC9
- KIAA0116
- KIAA1008
- MAPKAPK2
- MTR3
- NUDT20
- OIP2
- PKB
- PMSCL1
- RAC
- RNF162B
- RRP4
- RRP40
- RRP41
- RRP42
- RRP43
- RRP44
- RRP46
- SEP1
- SKI6
- SMIF
- TIS11B
- XRN1
- YWHAB
- ZFP36L1
|
Homo sapiens (human)
|
|
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
|
|
|
- AKT1
- CALM
- CALM1
- CAM
- CAM1
- DHFR
- DYT5
- GCH
- GCH1
- GCHFR
- GFRP
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- NOS3
- PKB
- PRKG2
- PRKGR2
- PTS
- RAC
- SPR
|
Homo sapiens (human)
|
|
KSRP (KHSRP) binds and destabilizes mRNA
|
|
|
- AKT1
- CML28
- CSBP
- CSBP1
- CSBP2
- CSL4
- CSPB1
- DAN
- DCP2
- DIS3
- EXOSC1
- EXOSC2
- EXOSC3
- EXOSC4
- EXOSC5
- EXOSC6
- EXOSC7
- EXOSC8
- EXOSC9
- FUBP2
- KHSRP
- KIAA0116
- KIAA1008
- MAPK11
- MAPK14
- MTR3
- MXI2
- NUDT20
- OIP2
- PARN
- PKB
- PMSCL1
- PRKM11
- RAC
- RRP4
- RRP40
- RRP41
- RRP42
- RRP43
- RRP44
- RRP46
- SAPK2
- SAPK2A
- SAPK2B
- SKI6
- YWHAZ
|
Homo sapiens (human)
|
|
mTORC1-mediated signalling
|
|
|
- AKT1S1
- C11orf59
- C7orf59
- EEF2K
- EIF4B
- EIF4E
- EIF4EBP1
- EIF4EL1
- EIF4F
- EIF4G
- EIF4G1
- EIF4GI
- FKBP1
- FKBP12
- FKBP1A
- FRAP
- FRAP1
- FRAP2
- GBL
- HBXIP
- KIAA1303
- LAMTOR1
- LAMTOR2
- LAMTOR3
- LAMTOR4
- LAMTOR5
- LST8
- MAP2K1IP1
- MAPBPIP
- MAPKSP1
- MLST8
- MTOR
- PDRO
- PRAS40
- RAFT1
- RAPT1
- RAPTOR
- RHEB
- RHEB2
- ROBLD3
- RPS6
- RPS6KB1
- RPTOR
- RRAGA
- RRAGB
- RRAGC
- RRAGD
- SLC38A9
- STK14A
- URLC11
- XIP
- YWHAB
|
Homo sapiens (human)
|
|
HSF1-dependent transactivation
|
|
|
- AKT1S1
- CAM2
- CAMK
- CAMK-II
- CAMK2
- CAMK2A
- CAMK2B
- CAMK2D
- CAMK2G
- CAMKA
- CAMKB
- CAMKD
- CAMKG
- CRYA2
- CRYAB
- CRYAC
- DNAJ1
- DNAJB1
- E2IG1
- FRAP
- FRAP1
- FRAP2
- GBL
- HDJ1
- HSBP1
- HSC70
- HSF1
- HSF1BP
- HSP22
- HSP72
- HSP73
- HSP90A
- HSP90AA1
- HSP90AB1
- HSP90B
- HSPA1
- HSPA10
- HSPA1A
- HSPA1B
- HSPA1L
- HSPA8
- HSPB5
- HSPB8
- HSPC1
- HSPC2
- HSPC3
- HSPCA
- HSPCB
- HSPF1
- HSTF1
- HSX70
- KIAA0968
- KIAA1303
- LST8
- MLST8
- MTOR
- PRAS40
- RAFT1
- RAPT1
- RAPTOR
- RPTOR
|
Homo sapiens (human)
|
|
Activation of PKB
|
|
|
- AKT2
- C20orf97
- CTMP
- NIPK
- PDK1
- PDPK1
- SKIP3
- THEM4
- TRB3
- TRIB3
|
Homo sapiens (human)
|
|
Inhibition of TSC complex formation by PKB
|
|
|
- AKT2
- KIAA0243
- TSC
- TSC1
- TSC2
- TSC4
|
Homo sapiens (human)
|
|
PDE3B signalling
|
|
|
|
Homo sapiens (human)
|
|
L1CAM interactions
|
|
|
- ALCAM
- APT2
- AXT
- CAML1
- CD24
- CD24A
- CNTN1
- CNTN2
- CSPG3
- DRT
- EPHB2
- EPHT3
- EPTH3
- ERK
- GAP43
- HEK5
- L1CAM
- LAMA
- LAMA1
- LAMB1
- LAMB2
- LAMC1
- LYPLA2
- MEMD
- MIC5
- NCAN
- NEUR
- RANBP9
- RANBPM
- TAG1
- TAX1
- TYRO5
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Homo sapiens (human)
|
|
Gluconeogenesis
|
|
|
- ALDA
- ALDB
- ALDC
- ALDOA
- ALDOB
- ALDOC
- C10orf134
- ENO1
- ENO1L1
- ENO2
- ENO3
- ENO4
- FBP
- FBP1
- FBP2
- G3PP
- G6PC
- G6PC1
- G6PC2
- G6PC3
- G6PT
- G6PT1
- GAPD
- GAPD2
- GAPDH
- GAPDH2
- GAPDHS
- GAPDS
- GPI
- IGRP
- MBPB1
- MPB1
- PC
- PCK1
- PCK2
- PEPCK1
- PEPCK2
- PGAM1
- PGAM2
- PGAMA
- PGAMM
- PGK1
- PGK2
- PGKA
- PGKB
- SLC37A1
- SLC37A4
- TPI
- TPI1
- UGRP
|
Homo sapiens (human)
|
|
Fructose catabolism
|
|
|
- ALDB
- ALDC
- ALDH1
- ALDH1A1
- ALDOB
- DAK
- GLYCTK
- HBEBP4
- KHK
- PUMB1
- TKFC
|
Homo sapiens (human)
|
|
RND1 GTPase cycle
|
|
|
- ALDH10
- ALDH3A2
- ANKRD26
- APE
- ARHGAP35
- ARHGAP5
- ARMS
- BP230
- BP240
- BPAG1
- C1orf8
- C6orf143
- CAV
- CAV1
- CCDC88A
- CPD
- DEPDC1B
- DLG5
- DMH
- DRCC1
- DSP
- DST
- DT
- ECK
- EPHA2
- EPSTI1
- ESA1
- FALDH
- FAM135A
- FAM83B
- FLOT2
- FRS2
- FRS3
- GRB1
- GRB7
- GRDN
- GRF1
- GRLF1
- HNRPG
- KIAA0042
- KIAA0583
- KIAA0720
- KIAA0728
- KIAA1074
- KIAA1212
- KIAA1215
- KIAA1250
- KIAA1411
- KIAA1722
- KIDINS220
- KIF14
- LEMD3
- M17S1
- MAN1
- MUC13
- NGAP
- NOV
- P190A
- PDLG
- PIK3R1
- PIK3R2
- PKP4
- PLEKHG5
- PLXN1
- PLXNA1
- PNP1
- PTP1E
- PTPL1
- PTPN13
- RASAL2
- RBMX
- RBMXP1
- RECC
- RHO6
- RHOGAP5
- RND1
- RRAS2
- SCG10
- SCGN10
- SOC
- STB1
- STB2
- STIP1
- STMN2
- TC21
- TFRC
- TMEM59
- TRP32
- TXL
- TXNL
- TXNL1
- UBXD5
- UBXN11
- VANGL1
- VANGL2
- WDR6
- XTP8
- p190ARHOGAP
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Homo sapiens (human)
|
|