GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **501 - 525** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Manipulation of host energy metabolism	6 kDa early secretory antigenic target Alpha-enolase Phosphoglycerate kinase 1	P00558 P06733 P9WNK7	ENO1 ENO1L1 MBPB1 MPB1 PGK1 PGKA esaT6 esxA	Homo sapiens (human)
PP2A-mediated dephosphorylation of key metabolic factors	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 Carbohydrate-responsive element-binding protein Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	P16118 P30153 P30154 P62714 P67775 Q14738 Q9NP71	BHLHD14 F6PK MIO MLXIPL PFKFB1 PFRX PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5D WBSCR14	Homo sapiens (human)
Mitochondrial protein import	4-hydroxybenzoate polyprenyltransferase, mitochondrial 60 kDa heat shock protein, mitochondrial ADP/ATP translocase 1 ADP/ATP translocase 3 ATP synthase F(0) complex subunit C1, mitochondrial ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial Aconitate hydratase, mitochondrial COX assembly mitochondrial protein 2 homolog Citrate synthase, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 Cx9C motif-containing protein 4 Cytochrome c oxidase assembly factor 4 homolog, mitochondrial Cytochrome c oxidase assembly factor 6 homolog Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase copper chaperone Cytochrome c1, heme protein, mitochondrial Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial FAD-linked sulfhydryl oxidase ALR Frataxin, mitochondrial GrpE protein homolog 1, mitochondrial GrpE protein homolog 2, mitochondrial Iron-sulfur cluster co-chaperone protein HscB Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial MICOS complex subunit MIC19 Metaxin-1 Metaxin-2 Mitochondrial chaperone BCS1 Mitochondrial import inner membrane translocase subunit TIM14 Mitochondrial import inner membrane translocase subunit TIM16 Mitochondrial import inner membrane translocase subunit TIM44 Mitochondrial import inner membrane translocase subunit TIM50 Mitochondrial import inner membrane translocase subunit Tim10 B Mitochondrial import inner membrane translocase subunit Tim10 Mitochondrial import inner membrane translocase subunit Tim13 Mitochondrial import inner membrane translocase subunit Tim17-A Mitochondrial import inner membrane translocase subunit Tim17-B Mitochondrial import inner membrane translocase subunit Tim21 Mitochondrial import inner membrane translocase subunit Tim22 Mitochondrial import inner membrane translocase subunit Tim23 Mitochondrial import inner membrane translocase subunit Tim8 A Mitochondrial import inner membrane translocase subunit Tim8 B Mitochondrial import inner membrane translocase subunit Tim9 Mitochondrial import receptor subunit TOM20 homolog Mitochondrial import receptor subunit TOM22 homolog Mitochondrial import receptor subunit TOM40 homolog Mitochondrial import receptor subunit TOM5 homolog Mitochondrial import receptor subunit TOM6 homolog Mitochondrial import receptor subunit TOM7 homolog Mitochondrial import receptor subunit TOM70 Mitochondrial intermembrane space import and assembly protein 40 Mitochondrial-processing peptidase subunit alpha Mitochondrial-processing peptidase subunit beta NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial Non-selective voltage-gated ion channel VDAC1 Ornithine transcarbamylase, mitochondrial Presequence protease, mitochondrial Probable D-lactate dehydrogenase, mitochondrial Sorting and assembly machinery component 50 homolog Stress-70 protein, mitochondrial Tafazzin	O14925 O43615 O60220 O60830 O75390 O75431 O75439 O75746 O94826 O95169 O96008 P00480 P05496 P06576 P08574 P10809 P12235 P12236 P21796 P25705 P38646 P51553 P55789 P56277 P62072 Q10713 Q13505 Q14061 Q15388 Q16595 Q16635 Q3ZCQ8 Q49B96 Q5JRX3 Q5JTJ3 Q86WU2 Q8IWL3 Q8N4H5 Q8N4Q1 Q8TAA5 Q8WYQ3 Q96B49 Q96DA6 Q96H96 Q99595 Q99798 Q9BSY4 Q9BUK0 Q9BVV7 Q9HAV7 Q9NRP2 Q9NS69 Q9NX63 Q9NYJ1 Q9P0U1 Q9UJS0 Q9Y276 Q9Y3D7 Q9Y512 Q9Y584 Q9Y5J6 Q9Y5J7 Q9Y5J9 Q9Y5L4 Q9Y6H1	AAC1 AAC3 ACO2 AGC1 ALR ANT1 ANT3 ARALAR1 ATP5A ATP5A1 ATP5AL2 ATP5B ATP5F1A ATP5F1B ATP5G1 ATP5MC1 ATPM ATPMB ATPSB BCS1 BCS1L C16orf61 C18orf55 C19orf1 C1orf31 C22orf16 C2orf9 C6.1B C7orf17 C9orf105 CHCHD10 CHCHD2 CHCHD3 CHCHD4 CHCHD5 CHCHD7 CHCHD8 CL640 CMC2 CMC4 COA4 COA6 COQ2 COX17 COX19 CS CYC1 DDP DDP1 DDP2 DDPL DNAJC19 DNAJC20 E2IG2 EFE2 FRDA FXC1 FXN G4.5 GFER GREPEL1 GRP75 GRPEL1 GRPEL2 HERV1 HPO HSC20 HSCB HSP60 HSPA9 HSPA9B HSPD1 IDH3G INPP5E KIAA0016 KIAA0123 KIAA0719 KIAA1104 LDHD MAGMAS MIA40 MIC19 MIMT17 MIMT44 MINOS3 MP1 MPPA MPPB MTCP1 MTCP1NB MTX MTX1 MTX2 MTXN NDUFB8 OBTP OTC PAM16 PEREC1 PITRM1 PMPCA PMPCB PREP SAM50 SAMM50 SLC25A12 SLC25A13 SLC25A4 SLC25A6 TAFAZZIN TAZ TEX4 TIM10 TIM13B TIM14 TIM16 TIM17 TIM17A TIM17B TIM21 TIM22 TIM23 TIM44 TIM50 TIM8A TIM8B TIM9 TIM9A TIM9B TIMM10 TIMM10B TIMM13 TIMM13A TIMM13B TIMM14 TIMM16 TIMM17 TIMM17A TIMM17B TIMM21 TIMM22 TIMM23 TIMM44 TIMM50 TIMM8A TIMM8B TIMM9 TIMM9A TIMM9B TOM22 TOM40 TOM5 TOM6 TOM7 TOM70 TOMM07 TOMM20 TOMM22 TOMM40 TOMM5 TOMM6 TOMM7 TOMM70 TOMM70A VDAC VDAC1 X25 mt-HSP70	Homo sapiens (human)
Activation of C3 and C5	Complement C2 Complement C3 Complement C4-A Complement C4-B Complement C5 Complement factor B	P00751 P01024 P01031 P06681 P0C0L4 P0C0L5	BF BFD C2 C3 C4A C4B C4B_2 C5 CFB CO4 CPAMD1 CPAMD2 CPAMD3 CPAMD4	Homo sapiens (human)
Suppression of autophagy	Dual specificity protein phosphatase 16 N-acetyltransferase Eis Phosphatidylinositol-3-phosphatase Ras-related protein Rab-7a	O53361 P51149 P9WFK7 Q9BY84	DUSP16 KIAA1700 MKP7 RAB7 RAB7A eis sapM	Homo sapiens (human)
LXRs regulate gene expression linked to triglyceride lipolysis in adipose	Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta Perilipin-1 Retinoic acid receptor RXR-alpha Retinoic acid receptor RXR-beta	O60240 P19793 P28702 P55055 Q13133	LXRA LXRB NER NR1H2 NR1H3 NR2B1 NR2B2 PERI PLIN PLIN1 RXRA RXRB UNR	Homo sapiens (human)
Regulation of NFE2L2 gene expression	CREB-binding protein Histone acetyltransferase p300 Myc proto-oncogene protein Neurogenic locus notch homolog protein 1 Nuclear factor NF-kappa-B p105 subunit Nuclear factor erythroid 2-related factor 2 Transcription factor MafK Transcription factor p65	O60675 P01106 P19838 P46531 Q04206 Q09472 Q16236 Q92793	BHLHE39 CBP CREBBP EP300 MAFK MYC NFE2L2 NFKB1 NFKB3 NOTCH1 NRF2 P300 RELA TAN1	Homo sapiens (human)
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Ficolin-1 Ficolin-2 Ficolin-3 Mannan-binding lectin serine protease 1	O00602 O75636 P48740 Q15485	CRARF CRARF1 FCN1 FCN2 FCN3 FCNH FCNL FCNM HAKA1 MASP1 PRSS5	Homo sapiens (human)	G49108TO G57321FI
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor IX Coagulation factor VII Coagulation factor X Furin Growth arrest-specific protein 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S Vitamin K-dependent protein Z	P00734 P00740 P00742 P02818 P04070 P07225 P08709 P09958 P22891 Q14393	AXLLG BGLAP F10 F2 F7 F9 FUR FURIN GAS6 PACE PCSK3 PROC PROS PROS1 PROZ	Homo sapiens (human)
PKA activation	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Adenylate cyclase type 9 Calmodulin-1 Neurobeachin cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase catalytic subunit beta cAMP-dependent protein kinase catalytic subunit gamma cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type I-beta regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase type II-beta regulatory subunit	O43306 O60266 O60503 O95622 P0DP23 P10644 P13861 P17612 P22612 P22694 P31321 P31323 P40145 P51828 Q08462 Q08828 Q8NFM4 Q8NFP9	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 BCL8B CALM CALM1 CAM CAM1 KIAA0037 KIAA0422 KIAA0511 KIAA0520 KIAA1060 KIAA1544 LYST2 NBEA PKACA PKR1 PKR2 PRKACA PRKACB PRKACG PRKAR1 PRKAR1A PRKAR1B PRKAR2 PRKAR2A PRKAR2B TSE1	Homo sapiens (human)
Nephrin family interactions	Actin nucleation-promoting factor WASL Alpha-actinin-1 Alpha-actinin-2 Alpha-actinin-3 Alpha-actinin-4 CD2-associated protein Cytoplasmic protein NCK2 Kin of IRRE-like protein 1 Kin of IRRE-like protein 2 Kin of IRRE-like protein 3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 Nephrin Peripheral plasma membrane protein CASK Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Ras GTPase-activating-like protein IQGAP1 SH2/SH3 adapter protein NCK1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 1 Tyrosine-protein kinase Fyn	O00401 O00459 O14936 O43639 O43707 O60500 P06241 P12814 P16333 P27986 P35609 P42336 P42338 P46940 Q01082 Q08043 Q13813 Q6UWL6 Q86UL8 Q8IZU9 Q96J84 Q9Y5K6	ACTN1 ACTN2 ACTN3 ACTN4 ACVRINP1 AIP1 CASK CD2AP FYN GRB1 GRB4 IQGAP1 KIAA0051 KIAA0705 KIAA1867 KIRREL KIRREL1 KIRREL2 KIRREL3 LIN2 MAGI2 NCK NCK1 NCK2 NEAS NEPH1 NEPH2 NEPH3 NPHN NPHS1 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 SPTA2 SPTAN1 SPTB2 SPTBN1 WASL	Homo sapiens (human)
Impaired BRCA2 binding to RAD51	26S proteasome complex subunit SEM1 ATR-interacting protein BRCA1-associated RING domain protein 1 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN Breast cancer type 1 susceptibility protein Breast cancer type 2 susceptibility protein Cell cycle checkpoint control protein RAD9A Cell cycle checkpoint control protein RAD9B Cell cycle checkpoint protein RAD17 Cell cycle checkpoint protein RAD1 Checkpoint protein HUS1 DNA endonuclease RBBP8 DNA repair protein RAD50 DNA repair protein RAD51 homolog 1 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase 2-binding protein 1 DNA topoisomerase 3-alpha Double-strand break repair protein MRE11 Exonuclease 1 Fanconi anemia group J protein Histone acetyltransferase KAT5 Nibrin RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 RecQ-like DNA helicase BLM RecQ-mediated genome instability protein 1 RecQ-mediated genome instability protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Serine-protein kinase ATM Serine/threonine-protein kinase ATR	O60671 O60921 O60934 O75943 P15927 P27694 P35244 P35249 P35250 P38398 P40937 P40938 P49959 P51530 P51587 P54132 P60896 Q06609 Q13315 Q13472 Q13535 Q14191 Q6WBX8 Q8WXE1 Q92547 Q92878 Q92993 Q96E14 Q99638 Q99708 Q99728 Q9BSD3 Q9BX63 Q9H9A7 Q9UQ84	AGS1 ATM ATR ATRIP BACH1 BARD1 BLM BRCA1 BRCA2 BRIP1 C12orf32 C16orf75 C7orf76 C9orf76 CTIP DNA2 DNA2L DSS1 EXO1 EXOI FACD FANCD1 FANCJ FRP1 HEX1 HNGS1 HTATIP HUS1 KAT5 KIAA0083 KIAA0259 MRE11 MRE11A NBN NBS NBS1 P95 R24L RAD1 RAD17 RAD50 RAD51 RAD51A RAD9A RAD9B RBBP8 REC1 RECA RECQ2 RECQ3 RECQL2 RECQL3 REPA1 REPA2 REPA3 RFC2 RFC3 RFC4 RFC5 RHINO RHNO1 RMI1 RMI2 RNF53 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 SEM1 SHFDG1 SHFM1 TIP60 TOP3 TOP3A TOPBP1 WRN	Homo sapiens (human)
Constitutive Signaling by Aberrant PI3K in Cancer	Amphiregulin B-lymphocyte antigen CD19 BDNF/NT-3 growth factors receptor Beta-klotho Brain-derived neurotrophic factor Epidermal growth factor receptor Epigen Estrogen receptor beta Estrogen receptor Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fms-related tyrosine kinase 3 ligand GRB2-associated-binding protein 1 GRB2-associated-binding protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Mast/stem cell growth factor receptor Kit NT-3 growth factor receptor Neurotrophin-3 Neurotrophin-4 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Phosphoinositide 3-kinase adapter protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Proto-oncogene vav Protransforming growth factor alpha Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Rho-related GTP-binding protein RhoG Striatin T-cell receptor-associated transmembrane adapter 1 T-cell-specific surface glycoprotein CD28 T-lymphocyte activation antigen CD80 T-lymphocyte activation antigen CD86 Tyrosine-protein kinase Fyn Tyrosine-protein kinase Lck Tyrosine-protein phosphatase non-receptor type 11	O00329 O00459 O14511 O14944 O15520 O43320 O43815 O76093 O95750 P00533 P01127 P01133 P01135 P03372 P04626 P05230 P06239 P06241 P08581 P08620 P09038 P09619 P10721 P10747 P10767 P11487 P12931 P14210 P15153 P15391 P15498 P15514 P16234 P20783 P21781 P22455 P23560 P27986 P31371 P33681 P34130 P35070 P35568 P36888 P42081 P42336 P42338 P49771 P56975 P63000 P84095 Q02297 Q06124 Q13480 Q16288 Q16620 Q6PIZ9 Q6UW88 Q6ZUJ8 Q86Z14 Q8WU20 Q8WWG1 Q92569 Q92731 Q99075 Q9GZV9 Q9HCT0 Q9NP95 Q9UQC2 Q9Y4H2	AREG AREGB ARHG BCAP BDNF BTC CD135 CD19 CD28 CD28LG CD28LG1 CD28LG2 CD80 CD86 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ESR ESR1 ESR2 ESTRB FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GGF GRB1 HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRGA HST HST2 HSTF1 HSTF2 HYPF INT2 IRS1 IRS2 JTK2 KGF KIAA0571 KIT KLB KS3 LAB7 LCK MET MLN19 NDF NEU NGL NR3A1 NR3A2 NRG1 NRG2 NRG3 NRG4 NTAK NTF3 NTF4 NTF5 NTRK2 NTRK3 PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PIK3AP1 PIK3C1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTP2C PTPN11 RAC1 RAC2 RHEPDGFRA RHOG SCFR SDGF SHPTP2 SIS SMDF SRC SRC1 STK1 STRN TC25 TCRIM TGFA TKF TRAT1 TRKB TRKC VAV VAV1	Homo sapiens (human)
tandutinib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
crenolanib-resistant FLT3 mutants	Receptor-type tyrosine-protein kinase FLT3	P36888	CD135 FLK2 FLT3 STK1	Homo sapiens (human)
MECP2 regulates transcription of neuronal ligands	Brain-derived neurotrophic factor Corticoliberin Delta-like protein 1 Histone deacetylase 1 Paired amphipathic helix protein Sin3a Somatostatin	O00548 P06850 P23560 P61278 Q13547 Q96ST3	BDNF CRH DLL1 HDAC1 RPD3L1 SIN3A SST	Homo sapiens (human)
Defective factor XII causes hereditary angioedema	Coagulation factor XII Plasma kallikrein Prothrombin	P00734 P00748 P03952	F12 F2 KLK3 KLKB1	Homo sapiens (human)
DDX58/IFIH1-mediated induction of interferon-alpha/beta	ATP-dependent RNA helicase DHX58 Antiviral innate immune response receptor RIG-I E3 ISG15--protein ligase HERC5 E3 ubiquitin-protein ligase RNF135 E3 ubiquitin-protein ligase TRIM4 E3 ubiquitin/ISG15 ligase TRIM25 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Interferon-induced helicase C domain-containing protein 1 Mitochondrial antiviral-signaling protein Mitochondrial import receptor subunit TOM70 NLR family member X1 Nucleoprotein ORF9b protein Protein NLRC5 Serine/threonine-protein kinase TBK1 Triokinase/FMN cyclase Ubiquitin-like modifier-activating enzyme 7 Ubiquitin-like protein ISG15 Ubiquitin/ISG15-conjugating enzyme E2 L6	O14933 O94826 O95786 P05161 P07900 P08238 P0DTC9 P0DTD2 P41226 Q14258 Q14653 Q3LXA3 Q7Z434 Q86UT6 Q86WI3 Q8IUD6 Q96C10 Q9BYX4 Q9C037 Q9UHD2 Q9UII4	9b CEB1 CEBP1 D11LGP2E DAK DDX58 DHX58 EFP G1P2 HERC5 HSP90A HSP90AA1 HSP90AB1 HSP90B HSPC1 HSPC2 HSPC3 HSPCA HSPCB IFIH1 IPS1 IRF3 ISG15 KIAA0719 KIAA1271 LGP2 MAVS MDA5 N NAK NLRC5 NLRX1 NOD27 NOD4 NOD5 NOD9 RH116 RIGI RNF135 RNF147 RNF87 TBK1 TKFC TOM70 TOMM70 TOMM70A TRIM25 TRIM4 UBA7 UBCH8 UBE1L UBE2 UBE2L6 UCRP VISA ZNF147	Homo sapiens (human)
Trafficking of myristoylated proteins to the cilium	ADP-ribosylation factor-like protein 3 Cystin-1 Nephrocystin-3 Protein XRP2 Protein unc-119 homolog B	A6NIH7 O75695 P36405 Q717R9 Q7Z494	ARFL3 ARL3 CYS1 KIAA2000 NPHP3 RP2 UNC119B	Homo sapiens (human)
TNF signaling	BAG family molecular chaperone regulator 4 Disintegrin and metalloproteinase domain-containing protein 17 Receptor-interacting serine/threonine-protein kinase 1 TNF receptor-associated factor 2 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor	O95429 P01375 P19438 P78536 Q12933 Q13546 Q15628	ADAM17 BAG4 CSVP RIP RIP1 RIPK1 SODD TACE TNF TNFA TNFAR TNFR1 TNFRSF1A TNFSF2 TRADD TRAF2 TRAP3	Homo sapiens (human)
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 16 A disintegrin and metalloproteinase with thrombospondin motifs 18 A disintegrin and metalloproteinase with thrombospondin motifs 1 A disintegrin and metalloproteinase with thrombospondin motifs 4 A disintegrin and metalloproteinase with thrombospondin motifs 5 A disintegrin and metalloproteinase with thrombospondin motifs 8 A disintegrin and metalloproteinase with thrombospondin motifs 9 Aggrecan core protein Alpha-2-macroglobulin Basement membrane-specific heparan sulfate proteoglycan core protein Basigin Bone morphogenetic protein 1 Brevican core protein CD44 antigen Cadherin-1 Calpain small subunit 1 Calpain small subunit 2 Calpain-1 catalytic subunit Calpain-10 Calpain-11 Calpain-12 Calpain-13 Calpain-14 Calpain-15 Calpain-2 catalytic subunit Calpain-3 Calpain-5 Calpain-6 Calpain-7 Calpain-8 Calpain-9 Calpastatin Caspase-3 Cathepsin G Cathepsin K Cathepsin L2 Cathepsin S Collagenase 3 Decorin Disintegrin and metalloproteinase domain-containing protein 10 Disintegrin and metalloproteinase domain-containing protein 15 Disintegrin and metalloproteinase domain-containing protein 8 Interstitial collagenase Kallikrein-7 Laminin subunit alpha-3 Laminin subunit alpha-5 Laminin subunit beta-1 Laminin subunit beta-3 Laminin subunit gamma-1 Laminin subunit gamma-2 Macrophage metalloelastase Matrilysin Matrix metalloproteinase-14 Matrix metalloproteinase-15 Matrix metalloproteinase-19 Matrix metalloproteinase-20 Matrix metalloproteinase-9 Neutrophil collagenase Neutrophil elastase Nicastrin Nidogen-1 Opticin Osteopontin Plasminogen Presenilin-1 Procathepsin L Serine protease HTRA1 Signal peptide, CUB and EGF-like domain-containing protein 1 Signal peptide, CUB and EGF-like domain-containing protein 3 Stromelysin-1 Stromelysin-2 Stromelysin-3 Tolloid-like protein 1 Tolloid-like protein 2 Transmembrane protease serine 6	A6NHC0 A8MX76 O14672 O14815 O15230 O15484 O43897 O60882 O60911 O75173 O75808 P00747 P01023 P03956 P04632 P07384 P07585 P07711 P07942 P08246 P08253 P08254 P08311 P09237 P09238 P10451 P11047 P12830 P13497 P14543 P14780 P16070 P16112 P17655 P20807 P20810 P22894 P24347 P25774 P35613 P39900 P42574 P43235 P45452 P49768 P49862 P50281 P51511 P78325 P98160 Q13444 Q13751 Q13753 Q16787 Q6MZZ7 Q6ZSI9 Q8IU80 Q8IWY4 Q8IX30 Q8TE57 Q8TE60 Q92542 Q92743 Q96GW7 Q96L46 Q99542 Q9HC96 Q9P2N4 Q9UBM4 Q9UHI8 Q9UMQ6 Q9UNA0 Q9UP79 Q9Y6L7 Q9Y6Q1 Q9Y6W3	A2M ACAN AD3 ADAM10 ADAM15 ADAM8 ADAMTS1 ADAMTS11 ADAMTS16 ADAMTS18 ADAMTS21 ADAMTS4 ADAMTS5 ADAMTS8 ADAMTS9 ADMP2 AGC1 BCAN BEHAB BMP1 BNSP BSG CALPM CANP3 CANPL1 CANPL2 CANPL3 CANPX CAPN1 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14 CAPN15 CAPN2 CAPN3 CAPN4 CAPN5 CAPN6 CAPN7 CAPN8 CAPN9 CAPNS CAPNS1 CAPNS2 CASP3 CAST CATL2 CD44 CDH1 CDHE CEGF3 CLG CLG1 CLG4A CLG4B CPAMD5 CPP32 CSPG1 CSPG7 CTSG CTSK CTSL CTSL1 CTSL2 CTSO CTSO2 CTSS CTSU CTSV DCN ELA2 ELANE HME HSPG2 HTRA HTRA1 KIAA0253 KIAA0533 KIAA0688 KIAA0932 KIAA1312 KIAA1346 KIAA1845 KIAA1907 KIAA2029 KLK7 KUZ LAMA3 LAMA5 LAMB1 LAMB2 LAMB2T LAMB3 LAMC1 LAMC2 LAMNA LAMNB1 LAMNB2 LHR MADM MDC15 MDU2 MDU3 METH1 METH2 MIC4 MMP1 MMP10 MMP11 MMP12 MMP13 MMP14 MMP15 MMP18 MMP19 MMP2 MMP20 MMP3 MMP7 MMP8 MMP9 MPSL1 MS2 MSK16 NCL1 NCL2 NCL3 NCL4 NCSTN NID NID1 OPN OPT OPTC PALBH PCOLC PLG PRSS11 PRSS6 PS1 PSEN1 PSNL1 PUMP1 RASI SCCE SCUBE1 SCUBE3 SLRR1B SOLH SPP1 STMY1 STMY2 STMY3 TLL TLL1 TLL2 TMPRSS6 UVO	Homo sapiens (human)
Signaling by ERBB2 KD Mutants	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Epidermal growth factor receptor Erbin GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Receptor tyrosine-protein kinase erbB-2 SHC-transforming protein 1 Son of sevenless homolog 1	O14511 O14944 P00533 P01111 P01112 P01133 P04626 P07900 P19174 P27986 P29353 P35070 P42336 P56975 Q02297 Q07889 Q13480 Q16543 Q8WWG1 Q96RT1 Q99075	BTC CDC37 CDC37A DTR DTS EGF EGFR ERBB ERBB1 ERBB2 ERBB2IP ERBIN EREG GAB1 GGF GRB1 HBEGF HEGFL HER1 HER2 HGL HRAS HRAS1 HRGA HSP90A HSP90AA1 HSPC1 HSPCA KIAA1225 LAP2 MLN19 NDF NEU NGL NRAS NRG1 NRG2 NRG3 NRG4 NTAK PIK3CA PIK3R1 PLC1 PLCG1 SHC SHC1 SHCA SMDF SOS1	Homo sapiens (human)
Cyclin A:Cdk2-associated events at S phase entry	CDK-activating kinase assembly factor MAT1 CDK5 and ABL1 enzyme substrate 1 Cyclin-A1 Cyclin-A2 Cyclin-H Cyclin-dependent kinase 2 Cyclin-dependent kinase 7 Cyclin-dependent kinase inhibitor 1 Cyclin-dependent kinase inhibitor 1B Fizzy-related protein homolog Histone-binding protein RBBP4 M-phase inducer phosphatase 1 M-phase inducer phosphatase 2 Myc proto-oncogene protein Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Protein max RAC-alpha serine/threonine-protein kinase RAC-beta serine/threonine-protein kinase RAC-gamma serine/threonine-protein kinase Retinoblastoma-associated protein Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5 Wee1-like protein kinase	P01106 P06400 P20248 P24941 P30291 P30304 P30305 P31749 P31751 P38936 P46527 P50613 P51946 P51948 P61244 P78396 Q01094 Q08999 Q09028 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q8TDN4 Q96GY3 Q9UM11 Q9Y243	AKT1 AKT2 AKT3 BARA BHLHD4 BHLHE39 C14orf46 CABLES CABLES1 CAK CAK1 CAP20 CAP35 CCN1 CCNA CCNA1 CCNA2 CCNH CDC25A CDC25B CDC25HU2 CDH1 CDK2 CDK7 CDKN1 CDKN1A CDKN1B CDKN2 CDKN7 CIP1 CXCDC1 DP1 DP2 E2F1 E2F4 E2F5 FYR FZR FZR1 KIAA1242 KIAA2037 KIP1 LIN37 LIN52 LIN54 LIN9 MAT1 MAX MDA6 MNAT1 MO15 MYC PIC1 PKB PKBG RAC RB1 RB2 RBAP48 RBBP3 RBBP4 RBL2 RNF66 SDI1 STK1 TFDP1 TFDP2 TGS WAF1 WEE1 p27	Homo sapiens (human)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	Histone-lysine N-methyltransferase 2C Histone-lysine N-methyltransferase 2D Lysine-specific demethylase 6A Nuclear receptor coactivator 6 PAX-interacting protein 1 PAXIP1-associated glutamate-rich protein 1 Protein dpy-30 homolog Retinoblastoma-binding protein 5 Set1/Ash2 histone methyltransferase complex subunit ASH2 WD repeat-containing protein 5	O14686 O15550 P61964 Q14686 Q15291 Q6ZW49 Q8NEZ4 Q9BTK6 Q9C005 Q9UBL3	AIB3 ALR ASH2L ASH2L1 BIG3 C16orf53 DPY30 HALR KDM6A KIAA0181 KIAA1506 KMT2C KMT2D MLL2 MLL3 MLL4 NCOA6 PA1 PAGR1 PAXIP1 PAXIP1L PTIP RAP250 RBBP5 RBQ3 TRBP UTX WDR5	Homo sapiens (human)
SDK interactions	Protein sidekick-1 Protein sidekick-2	Q58EX2 Q7Z5N4	KIAA1514 SDK1 SDK2	Homo sapiens (human)

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