Loss of phosphorylation of MECP2 at T308
|
|
|
- CALM
- CALM1
- CAM
- CAM1
- CAMK
- CAMK-GR
- CAMK4
- CAMKIV
- PKACA
- PRKACA
|
|
ROBO receptors bind AKAP5
|
|
|
- AKAP5
- AKAP79
- CALNA2
- CALNB
- CNA2
- KIAA1568
- PKACA
- PKCA
- PKR2
- PPP3CB
- PRKACA
- PRKACB
- PRKACG
- PRKAR2
- PRKAR2A
- PRKCA
- ROBO2
|
|
Conjugation of salicylate with glycine
|
|
|
- ACGNAT
- ACSM2
- ACSM2A
- ACSM2B
- ACSM4
- ACSM5
- C6orf140
- CAT
- GAT
- GLYAT
- GLYATL1
- GLYATL2
- GLYATL3
- GNAT
- MACS2
- MACS3
|
|
RAF activation
|
|
|
- ARAF
- ARAF1
- BRAF
- BRAF1
- BRAP
- CALM
- CALM1
- CAM
- CAM1
- CAM2
- CAMK
- CAMK-II
- CAMK2
- CAMK2A
- CAMK2B
- CAMK2D
- CAMK2G
- CAMKA
- CAMKB
- CAMKD
- CAMKG
- CTAK1
- EMK2
- HRAS
- HRAS1
- JAK2
- KIAA0044
- KIAA0862
- KIAA0968
- KSR
- KSR1
- MAP2K1
- MAP2K2
- MAP3K11
- MARK3
- MEK1
- MEK2
- MKK2
- MLK3
- MRAS
- NRAS
- PHB
- PHB1
- PKS
- PKS2
- PPP1CB
- PPP1CC
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PRKMK1
- PRKMK2
- PTK1
- RAF
- RAF1
- RAFB1
- RNF52
- RRAS3
- SHOC2
- SPRK
- SRC
- SRC1
- YWHAB
|
|
NGF-stimulated transcription
|
|
|
- 1R21
- ARC
- ASCL1
- ASH1
- ATF1
- ATF2
- BHLHA18
- BHLHA46
- BHLHB20
- BHLHB24
- BHLHB25
- BHLHB26
- BHLHB27
- C8FW
- CDK5
- CDK5R
- CDK5R1
- CDK5R2
- CDKN5
- CHD4
- CNSA3
- CREB2
- CREBP1
- DNM2
- DYN2
- EGR1
- EGR2
- EGR3
- EGR4
- ELK1
- EP300
- F3
- FOS
- FOSB
- FOSL1
- FRA1
- G0S3
- G0S7
- GIG2
- HASH1
- HEB
- HEIR1
- HTF4
- ID
- ID1
- ID2
- ID3
- ID4
- JUNB
- JUND
- KIAA0278
- KROX20
- KROX24
- LYL1
- MADER
- MEF2D
- NAB1
- NAB2
- NCK5A
- NCK5AI
- NRSF
- P300
- PILOT
- PSSALRE
- RAD
- REST
- RRAD
- SGK
- SGK1
- SH3D2C
- SH3GL3
- SRF
- TCF12
- TPH
- TPH1
- TPRH
- TRB1
- TRIB1
- TRPH
- VGF
- XBR
- ZNF225
|
|
TRAF3-dependent IRF activation pathway
|
|
|
- 1C
- CAP-1
- CBP
- CRAF1
- CREBBP
- DDX58
- EFP
- EP300
- IFB
- IFIH1
- IFNB
- IFNB1
- IKBKE
- IKKE
- IKKI
- IPS1
- IRF3
- IRF7
- KIAA0151
- KIAA1271
- M
- MAVS
- MDA5
- NAK
- NS1
- P300
- RH116
- RIGI
- RNF135
- RNF147
- RNF87
- SIKE
- SIKE1
- TBK1
- TRAF3
- TRAFAMN
- TRIM25
- TRIM4
- VISA
- ZNF147
|
|
Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2)
|
|
|
|
|
GAB1 signalosome
|
|
|
- AREG
- AREGB
- BTC
- CBP
- CSK
- DTR
- DTS
- EGF
- EGFR
- EPGN
- ERBB
- ERBB1
- EREG
- GAB1
- GRB1
- HBEGF
- HEGFL
- HER1
- PAG
- PAG1
- PIK3CA
- PIK3R1
- PTP2C
- PTPN11
- PXN
- SDGF
- SHPTP2
- SRC
- SRC1
- TGFA
|
|
Inhibition of replication initiation of damaged DNA by RB1/E2F1
|
|
|
- DP1
- DP2
- E2F1
- POLA
- POLA1
- POLA2
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R3B
- PPP2R3L
- PRIM1
- PRIM2
- PRIM2A
- RB1
- RBBP3
- TFDP1
- TFDP2
|
|
RNA Polymerase III Chain Elongation
|
- DNA-directed RNA polymerase III subunit RPC10
- DNA-directed RNA polymerase III subunit RPC1
- DNA-directed RNA polymerase III subunit RPC2
- DNA-directed RNA polymerase III subunit RPC3
- DNA-directed RNA polymerase III subunit RPC4
- DNA-directed RNA polymerase III subunit RPC5
- DNA-directed RNA polymerase III subunit RPC6
- DNA-directed RNA polymerase III subunit RPC7-like
- DNA-directed RNA polymerase III subunit RPC7
- DNA-directed RNA polymerase III subunit RPC8
- DNA-directed RNA polymerase III subunit RPC9
- DNA-directed RNA polymerases I and III subunit RPAC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC1
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- DNA-directed RNA polymerases I, II, and III subunit RPABC3
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- DNA-directed RNA polymerases I, II, and III subunit RPABC5
- Protein POLR1D, isoform 2
|
|
- BN51
- BN51T
- CRCP
- KIAA1452
- KIAA1665
- POLR1C
- POLR1D
- POLR1E
- POLR2E
- POLR2F
- POLR2H
- POLR2K
- POLR2L
- POLR3A
- POLR3B
- POLR3C
- POLR3D
- POLR3E
- POLR3F
- POLR3G
- POLR3GL
- POLR3H
- POLR3K
- POLRF
- RPC11
- RPC8
|
|
PCP/CE pathway
|
|
|
- ARH12
- ARHA
- DAAM1
- DVL1
- DVL2
- DVL3
- FZD1
- FZD3
- FZD6
- FZD7
- INT1
- JTK5A
- KIAA0208
- KIAA0666
- KIAA1215
- NTRKR2
- PFN1
- RAC1
- RAC2
- RAC3
- RHO12
- RHOA
- ROR2
- RYK
- STB1
- TC25
- VANGL2
- WNT1
- WNT11
- WNT4
- WNT5A
- WNT5B
|
|
PLC beta mediated events
|
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
- Guanine nucleotide-binding protein G(q) subunit alpha
- Guanine nucleotide-binding protein subunit alpha-11
- Guanine nucleotide-binding protein subunit alpha-14
- Guanine nucleotide-binding protein subunit alpha-15
- Inositol 1,4,5-trisphosphate receptor type 2
- Inositol 1,4,5-trisphosphate receptor type 3
- Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1
- S-adenosylhomocysteine hydrolase-like protein 1
|
|
- AHCYL1
- DCAL
- GA11
- GAQ
- GNA11
- GNA14
- GNA15
- GNA16
- GNAQ
- INSP3R1
- IRBIT
- ITPR1
- ITPR2
- ITPR3
- KIAA0581
- PLCB1
- PLCB2
- PLCB3
- PLCB4
- XPVKONA
|
|
Maturation of protein M
|
|
|
|
|
Sensory processing of sound by outer hair cells of the cochlea
|
|
|
- AIE75
- C12orf64
- C20orf145
- C6orf32
- C9orf75
- CASK
- CDH23
- CIB2
- CLIC5
- CMYA3
- DAL1
- DFNB25
- DFNB31
- DFNB36
- DFNB59
- DIFF48
- DXS552E
- EMP55
- EPB41L1
- EPB41L3
- EPS8
- EPS8L2
- EPS8R2
- ESPN
- ESPNL
- EZR
- FAM65B
- FSCN2
- GRXCR1
- GRXCR2
- GSN
- KCNQ4
- KIAA0338
- KIAA0386
- KIAA0987
- KIAA1526
- KIAA1774
- KIAA1812
- KIP2
- LHFPL5
- LIN2
- MPP1
- MSN
- MYH9
- MYO15
- MYO15A
- MYO1C
- MYO3A
- MYO3B
- MYO7A
- NEAS
- OTGN
- OTOG
- OTOGL
- PCDH15
- PJVK
- PL48
- PLS1
- PRES
- PTK9
- PTK9L
- RDX
- RIPOR2
- SANS
- SLC26A5
- SPTA2
- SPTAN1
- SPTB2
- SPTBN1
- STRC
- TMC1
- TMC2
- TMHS
- TMIE
- TPRN
- TWF1
- TWF2
- USH1B
- USH1C
- USH1F
- USH1G
- VIL2
- WHRN
- XIRP2
|
|
Defective MPDU1 causes CDG-1f
|
|
|
|
|
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
|
|
|
- AKT1
- AREG
- AREGB
- ARHG
- BCAP
- BTC
- C9orf26
- CD135
- CD19
- CD28
- CD28LG
- CD28LG1
- CD28LG2
- CD80
- CD86
- DER4
- DIF2
- DTR
- DTS
- EGF
- EGFR
- EPGN
- ERBB
- ERBB1
- ERBB2
- EREG
- ERK1
- ERK2
- ESR
- ESR1
- ESR2
- ESTRB
- FGF1
- FGF10
- FGF16
- FGF18
- FGF19
- FGF2
- FGF20
- FGF22
- FGF23
- FGF3
- FGF4
- FGF6
- FGF7
- FGF9
- FGFA
- FGFB
- FGFR4
- FLK2
- FLT3
- FLT3LG
- FRS2
- FYN
- GAB1
- GAB2
- GGF
- GRB1
- HBEGF
- HEGFL
- HER1
- HER2
- HGF
- HGL
- HPTA
- HRGA
- HST
- HST2
- HSTF1
- HSTF2
- HYPF
- IER3
- IEX1
- IL1F11
- IL1RL1
- IL33
- INS
- INSR
- INT2
- IRAK
- IRAK1
- IRAK4
- IRS1
- IRS2
- JTK2
- KGF
- KIAA0044
- KIAA0571
- KIAA0589
- KIT
- KLB
- KS3
- LAB7
- LCK
- MAPK1
- MAPK3
- MET
- MLN19
- MYD88
- NDF
- NEU
- NFHEV
- NGL
- NR3A1
- NR3A2
- NRG1
- NRG2
- NRG3
- NRG4
- NTAK
- PDGF2
- PDGFB
- PDGFR
- PDGFR1
- PDGFR2
- PDGFRA
- PDGFRB
- PI5P4KA
- PIK3AP1
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3R1
- PIK3R2
- PIK3R3
- PIP4K2A
- PIP4K2B
- PIP4K2C
- PIP5K1A
- PIP5K1B
- PIP5K1C
- PIP5K2
- PIP5K2A
- PIP5K2B
- PIP5K2C
- PKB
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PRG1
- PRKM1
- PRKM2
- PRKM3
- PTP2C
- PTPN11
- RAC
- RAC1
- RAC2
- RHEPDGFRA
- RHOG
- RNF85
- SCFR
- SDGF
- SHPTP2
- SIS
- SMDF
- SRC
- SRC1
- ST2
- STK1
- STM7
- STRN
- T1
- TC25
- TCRIM
- TGFA
- TKF
- TRAF6
- TRAT1
- VAV
- VAV1
|
|
Interferon alpha/beta signaling
|
|
|
- ABCE1
- ADAR
- ADAR1
- BIRC4BP
- BST2
- CD225
- CIG-42
- CIG-49
- CIG5
- CIS3
- DSRAD
- EGR1
- EIF2AK2
- G10P1
- G10P2
- G1P1
- G1P2
- G1P3
- GBP2
- HCP
- HEM45
- HLA-5.4
- HLA-6.0
- HLA-6.2
- HLA-A
- HLA-B
- HLA-C
- HLA-E
- HLA-F
- HLA-G
- HLA-H
- HLAA
- HLAB
- HLAC
- HLAE
- HLAF
- HLAG
- HLAH
- ICSBP1
- IFB
- IFI17
- IFI27
- IFI35
- IFI4
- IFI54
- IFI56
- IFI6
- IFI60
- IFIT1
- IFIT2
- IFIT3
- IFIT4
- IFIT5
- IFITM1
- IFITM2
- IFITM3
- IFNA1
- IFNA10
- IFNA13
- IFNA14
- IFNA16
- IFNA17
- IFNA2
- IFNA21
- IFNA2A
- IFNA2B
- IFNA2C
- IFNA4
- IFNA5
- IFNA6
- IFNA7
- IFNA8
- IFNAI1
- IFNAR
- IFNAR1
- IFNB
- IFNB1
- IFP35
- IHPK2
- IP6K2
- IRF1
- IRF2
- IRF3
- IRF4
- IRF5
- IRF6
- IRF7
- IRF8
- IRF9
- ISG15
- ISG20
- ISG54
- ISG56
- ISG58
- ISG60
- ISGF3G
- JAK1
- JAK1A
- JAK1B
- KPNA1
- KPNB1
- KROX24
- LMP7
- MOP5
- MUM1
- MX1
- MX2
- N
- NTF97
- OAS1
- OAS2
- OAS3
- OASL
- OIAS
- PKR
- PRKR
- PSMB5i
- PSMB8
- PTP1C
- PTP2C
- PTPN11
- PTPN6
- RCH2
- RI58
- RING10
- RLI
- RNASEL
- RNASEL1
- RNASELI
- RNS4
- RNS4I
- RPS27A
- RSAD2
- SAMHD1
- SHPTP2
- SOCS1
- SOCS3
- SSI1
- SSI3
- STAT1
- STAT2
- TIP3
- TRIP14
- TYK2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UCRP
- XAF1
- XIAPAF1
- Y2
- ZNF225
|
|
Glutamate and glutamine metabolism
|
|
|
- CCBL1
- FAM80A
- FAM80B
- GA
- GLNS
- GLS
- GLS1
- GLS2
- GLUD
- GLUD1
- GLUD2
- GLUDP1
- GLUL
- GOT2
- KIAA0838
- KIAA1238
- KYAT1
- KYAT4
- OAT
- PYCR1
- PYCR2
- PYCR3
- PYCRL
- RIMKLA
- RIMKLB
|
|
Peptide ligand-binding receptors
|
|
|
- ACKR1
- ACTHR
- AGT
- AGTBP
- AGTR1
- AGTR1A
- AGTR1B
- AGTR2
- AGTRL1
- APEL
- APJ
- APLN
- APLNR
- AT2R1
- AT2R1B
- AXOR12
- AZ3B
- BDK
- BDKRB1
- BDKRB2
- BKR2
- BRADYB1
- BRS3
- BV8
- C3
- C3AR1
- C3R1
- C5
- C5AR
- C5AR1
- C5AR2
- C5L2
- C5R1
- CCK
- CCKAR
- CCKBR
- CCKRA
- CCKRB
- CEPR
- CF2R
- CMKRL2
- CORT
- CPAMD1
- CPAMD4
- CXCL8
- DARC
- DRY12
- ECE1
- ECE2
- EDN1
- EDN2
- EDN3
- EDNRA
- EDNRB
- ETA
- ETBRLP2
- ETRA
- ETRB
- F2
- F2R
- F2RL1
- F2RL2
- F2RL3
- FY
- GAL
- GAL1
- GALN
- GALNR
- GALNR1
- GALNR2
- GALNR3
- GALR1
- GALR2
- GALR3
- GHSR
- GLBA
- GLNN
- GPD
- GPER
- GPER1
- GPR10
- GPR11
- GPR14
- GPR145
- GPR154
- GPR24
- GPR30
- GPR37
- GPR37L1
- GPR38
- GPR54
- GPR66
- GPR7
- GPR73
- GPR73L1
- GPR77
- GPR8
- GPRA
- GR3
- GRP
- GRPR
- HNFAG09
- IL8
- KEL
- KIAA0604
- KIAA1226
- KISS1
- KISS1R
- KNG
- KNG1
- MC1R
- MC2R
- MC3R
- MC4R
- MC5R
- MCH
- MCHR1
- MCHR2
- MLN
- MLNR
- MOR1
- MSHR
- MTLR
- MTLR1
- NLN
- NMB
- NMBR
- NMS
- NMU
- NMU2R
- NMUR1
- NMUR2
- NPB
- NPBWR1
- NPBWR2
- NPS
- NPSR1
- NPW
- NPY
- NPY1R
- NPY2R
- NPY4R
- NPY5R
- NPYR
- NPYR5
- NPYY1
- NTRR
- NTS
- NTSR1
- NTSR2
- OFQ
- OOR
- OPRD
- OPRD1
- OPRK
- OPRK1
- OPRL1
- OPRM1
- ORL1
- PAR1
- PAR2
- PAR3
- PAR4
- PDYN
- PENK
- PGR14
- PKR1
- PKR2
- PMCH
- PNOC
- PNP
- POMC
- PPL7
- PPL8
- PPNPB
- PPNPW
- PPY
- PPYR1
- PRH
- PRLH
- PRLHR
- PROK1
- PROK2
- PROKR1
- PROKR2
- PSAP
- PYY
- SAP1
- SERPINA8
- SLC1
- SLT
- SST
- SSTR1
- SSTR2
- SSTR3
- SSTR4
- SSTR5
- TGR1
- TR
- TRH
- TRHR
- URP
- UTS2
- UTS2B
- UTS2D
- UTS2R
- XK
- XKR1
- XRG1
|
|
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
|
|
|
- BLU
- CROC1
- IRAK
- IRAK1
- IRAK4
- IRF7
- MYD88
- RNF85
- TLR7
- TLR9
- TRAF6
- UBE2N
- UBE2V
- UBE2V1
- UEV1
|
|
Retinoid cycle disease events
|
|
|
- ABCA4
- ABCR
- BCP
- CRALBP
- CRBP1
- GCP
- HSD17B9
- LRAT
- OPN1LW
- OPN1MW
- OPN1SW
- PALB
- RBP1
- RBP4
- RCP
- RDH1
- RDH12
- RDH5
- RLBP1
- SDR7C2
- SDR9C5
- STRA6
- TTR
|
|
Electric Transmission Across Gap Junctions
|
|
|
- CX62
- GJA10
- GJA7
- GJA9
- GJC1
- GJD2
- MRS1
- PANX1
- PANX2
|
|
Degradation of the extracellular matrix
|
|
|
- A2M
- ACAN
- AD3
- ADAM10
- ADAM15
- ADAM8
- ADAMTS1
- ADAMTS11
- ADAMTS16
- ADAMTS18
- ADAMTS21
- ADAMTS4
- ADAMTS5
- ADAMTS8
- ADAMTS9
- ADMP2
- AGC1
- BCAN
- BEHAB
- BMP1
- BNSP
- BSG
- CALPM
- CANP3
- CANPL1
- CANPL2
- CANPL3
- CANPX
- CAPN1
- CAPN10
- CAPN11
- CAPN12
- CAPN13
- CAPN14
- CAPN15
- CAPN2
- CAPN3
- CAPN4
- CAPN5
- CAPN6
- CAPN7
- CAPN8
- CAPN9
- CAPNS
- CAPNS1
- CAPNS2
- CASP3
- CAST
- CATL2
- CD44
- CDH1
- CDHE
- CEGF3
- CLG
- CLG1
- CLG4A
- CLG4B
- CPAMD5
- CPP32
- CSPG1
- CSPG7
- CTSG
- CTSK
- CTSL
- CTSL1
- CTSL2
- CTSO
- CTSO2
- CTSS
- CTSU
- CTSV
- DCN
- ELA2
- ELANE
- HME
- HSPG2
- HTRA
- HTRA1
- KIAA0253
- KIAA0533
- KIAA0688
- KIAA0932
- KIAA1312
- KIAA1346
- KIAA1845
- KIAA1907
- KIAA2029
- KLK7
- KUZ
- LAMA3
- LAMA5
- LAMB1
- LAMB2
- LAMB2T
- LAMB3
- LAMC1
- LAMC2
- LAMNA
- LAMNB1
- LAMNB2
- LHR
- MADM
- MDC15
- MDU2
- MDU3
- METH1
- METH2
- MIC4
- MMP1
- MMP10
- MMP11
- MMP12
- MMP13
- MMP14
- MMP15
- MMP18
- MMP19
- MMP2
- MMP20
- MMP3
- MMP7
- MMP8
- MMP9
- MPSL1
- MS2
- MSK16
- NCL1
- NCL2
- NCL3
- NCL4
- NCSTN
- NID
- NID1
- OPN
- OPT
- OPTC
- PALBH
- PCOLC
- PLG
- PRSS11
- PRSS6
- PS1
- PSEN1
- PSNL1
- PUMP1
- RASI
- SCCE
- SCUBE1
- SCUBE3
- SLRR1B
- SOLH
- SPP1
- STMY1
- STMY2
- STMY3
- TLL
- TLL1
- TLL2
- TMPRSS6
- UVO
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DARPP-32 events
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- CALM
- CALM1
- CALNA
- CALNA2
- CALNA3
- CALNB
- CAM
- CAM1
- CDK5
- CDKN5
- CNA
- CNA2
- CNA3
- CNB
- DARPP32
- DPDE1
- DPDE2
- DPDE3
- PDE4A
- PDE4C
- PDE4D
- PKACA
- PKR1
- PKR2
- PPP1A
- PPP1CA
- PPP1R1B
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5D
- PPP3CA
- PPP3CB
- PPP3CC
- PPP3R1
- PRKACA
- PRKACB
- PRKACG
- PRKAR1
- PRKAR1A
- PRKAR1B
- PRKAR2
- PRKAR2A
- PRKAR2B
- PSSALRE
- TSE1
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Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
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- ACADL
- ECHS1
- HAD
- HAD1
- HADH
- HADHA
- HADHB
- HADHSC
- SCHAD
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