GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1526 - 1550** of **2074** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Abacavir metabolism	Adenosine deaminase-like protein Alcohol dehydrogenase 1A Cytosolic purine 5'-nucleotidase Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	P07327 P35558 P49902 Q6DHV7	ADAL ADAL1 ADH1 ADH1A NT5B NT5C2 NT5CP PCK1 PEPCK1 PNT5	Homo sapiens (human)
Defective ALG9 causes CDG-1l	Alpha-1,2-mannosyltransferase ALG9	Q9H6U8	ALG9 DIBD1	Homo sapiens (human)
Post-translational protein phosphorylation	Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1-antitrypsin Alpha-2-HS-glycoprotein Alpha-fetoprotein Ameloblastin Amelogenin, X isoform Amelotin Amyloid beta precursor like protein 2 Amyloid-beta precursor protein Anoctamin-8 Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B-100 Apolipoprotein E Apolipoprotein L1 BPI fold-containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Calumenin Ceruloplasmin Chordin-like protein 1 Coagulation factor V Complement C3 Complement C4-A Cystatin-C Cytoskeleton-associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin Extracellular serine/threonine protein kinase FAM20C Fibrillin-1 Fibrinogen alpha chain Fibrinogen gamma chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Follistatin-related protein 3 Galectin-1 Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest-specific protein 6 Heparin cofactor 2 Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Insulin-like growth factor-binding protein 7 Inter-alpha-trypsin inhibitor heavy chain H2 Interleukin-6 Kinectin Kininogen-1 Lactadherin Laminin subunit beta-1 Laminin subunit beta-2 Laminin subunit gamma-1 Latent-transforming growth factor beta-binding protein 1 Macrophage colony-stimulating factor 1 Matrilin-3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane-bound transcription factor site-1 protease Menin Mesothelin Metalloproteinase inhibitor 1 Neurosecretory protein VGF Nucleobindin-1 Osteopontin Palmitoleoyl-protein carboxylesterase NOTUM Patatin-like phospholipase domain-containing protein 2 Plasma alpha-L-fucosidase Proenkephalin-A Proprotein convertase subtilisin/kexin type 9 Protein Z-dependent protease inhibitor Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein eva-1 homolog A Protein shisa-5 Pseudokinase FAM20A Reticulocalbin-1 SPARC-like protein 1 Sarcoplasmic reticulum histidine-rich calcium-binding protein Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Stanniocalcin-2 Sulfhydryl oxidase 1 Syndecan-2 Tenascin Trans-Golgi network integral membrane protein 2 Transmembrane protein 132A Transport and Golgi organization protein 1 homolog Versican core protein Vitamin K-dependent protein C Wolframin von Willebrand factor A domain-containing protein 1	O00255 O00391 O00622 O14672 O14791 O15232 O15240 O43493 O43852 O76024 O76061 O95084 O95633 O95972 P00450 P01008 P01009 P01024 P01033 P01034 P01042 P01210 P02647 P02649 P02652 P02671 P02679 P02751 P02765 P02768 P02771 P02787 P04070 P04114 P05060 P05067 P05231 P05546 P07237 P07942 P08582 P08833 P09382 P09603 P0C0L4 P10451 P11047 P12259 P12644 P13521 P13611 P14314 P14625 P17936 P19022 P19823 P22692 P23327 P24593 P24821 P34741 P35555 P51654 P55268 Q02818 Q06481 Q07065 Q08431 Q12841 Q13103 Q13217 Q13316 Q13421 Q14393 Q14515 Q14703 Q14766 Q15084 Q15293 Q16270 Q24JP5 Q5JRA6 Q6P988 Q6PCB0 Q6Q788 Q6UX39 Q86UP2 Q8IXL6 Q8N114 Q8N4F0 Q8NBJ4 Q8NBP7 Q8WXD2 Q96AD5 Q96MK3 Q99217 Q9BRK3 Q9BTY2 Q9BU40 Q9GZV9 Q9H8M9 Q9HCE9 Q9NP70 Q9NQ76 Q9NRM1 Q9UK55 Q9UM21	A4 AAT AD1 ADAM10 AFP AHSG ALB AMBN AMELX AMG AMGX AMTN ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APOL APOL1 APP APPL2 AT3 ATGL AXLLG BDK BMP15 BMP2B BMP4 BNSP BPIFB2 BPIL1 C20orf184 C3 C4A C9orf155 CALU CCN1 CDH2 CDHN CG1 CHGB CHGC CHRDL1 CKAP4 CLGI CO4 CP CPAMD1 CPAMD2 CSF1 CSPG2 CST3 CYR61 DMP1 DMP4 DNAJC3 DVR4 ENAM ERBA2L ERP5 EVA1A F5 FAM176A FAM20A FAM20C FBN FBN1 FETUA FGA FGF23 FGG FLRG FN FN1 FRP FSTL1 FSTL3 FUCA2 G19P1 GAS6 GDF9B GIG1 GOLM1 GOLPH2 GPC3 GRP94 HCF2 HCP HPAFP HRC HSP90B1 HSPA5BP1 HSPC4 HSPG1 HXB HYPF IBP1 IBP3 IBP4 IBP5 IFNB2 IGFBP1 IGFBP10 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IGHEP2 IL6 ITIH2 KIAA0004 KIAA0091 KIAA0268 KIAA1583 KIAA1623 KNG KNG1 KTN1 KUZ LAMB1 LAMB2 LAMC1 LAMS LGALS1 LPLUNC2 LTBP1 MAC25 MADM MAP97 MATN3 MBTPS1 MELTF MEN1 MEPE MFGE8 MFI2 MGAT4A MIA3 MPF MSLN MXRA8 NARC1 NCAD NOTUM NRLN1 NUC NUCB1 OCI5 OPN P4HB P5 P58IPK PCSK9 PDI PDIA1 PDIA6 PENK PI PNPLA2 PO4DB PRKCSH PRKRI PROC PRSS23 PSF QSCN6 QSOX1 RAP3 RCN RCN1 S1P SCG1 SCG2 SCG3 SCOTIN SDC2 SERPINA1 SERPINA10 SERPINC1 SERPIND1 SHISA5 SKI1 SPARCL1 SPP1 SPP2 SPP24 STC2 TANGO TF TGN46 TGN51 TGOLN2 TIMP TIMP1 TMEM132A TMEM166 TMEM16H TNC TRA1 TXNDC7 VCAN VGF VWA1 WFS1 ZPI ZSIG13	Homo sapiens (human)
Plus-strand DNA synthesis	Gag polyprotein Gag-Pol polyprotein Peptidyl-prolyl cis-trans isomerase A Protein Rev Protein Vpr Protein Vpu Virion infectivity factor	P04585 P04591 P04618 P05919 P62937 P69723 P69726	CYPA PPIA gag gag-pol rev vif vpr vpu	Homo sapiens (human)
Signaling by PDGF	Collagen alpha-1(IV) chain Collagen alpha-1(IX) chain Collagen alpha-1(VI) chain Collagen alpha-2(IV) chain Collagen alpha-2(IX) chain Collagen alpha-2(VI) chain Collagen alpha-3(IV) chain Collagen alpha-3(IX) chain Collagen alpha-3(VI) chain Collagen alpha-4(IV) chain Collagen alpha-5(IV) chain Collagen alpha-5(VI) chain Collagen alpha-6(VI) chain Furin Osteopontin Plasminogen Platelet-derived growth factor D Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Thrombospondin-1 Thrombospondin-2 Thrombospondin-3 Thrombospondin-4 Tissue-type plasminogen activator Tyrosine-protein phosphatase non-receptor type 12	A6NMZ7 A8TX70 P00747 P00750 P01127 P02462 P07996 P08572 P09619 P09958 P10451 P12109 P12110 P12111 P16234 P20849 P29400 P35442 P35443 P49746 P53420 Q01955 Q05209 Q14050 Q14055 Q9GZP0	BNSP COL29A1 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 COL9A1 COL9A2 COL9A3 FUR FURIN IEGF OPN PACE PCSK3 PDGF2 PDGFB PDGFD PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PLAT PLG PTPN12 RHEPDGFRA SCDGFB SIS SPP1 THBS1 THBS2 THBS3 THBS4 TSP TSP1 TSP2 TSP3 TSP4 VWA4	Homo sapiens (human)
Defective SLC6A5 causes hyperekplexia 3 (HKPX3)	Sodium- and chloride-dependent glycine transporter 2	Q9Y345	GLYT2 NET1 SLC6A5	Homo sapiens (human)
Nucleotide catabolism	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	Q9Y3Z3	MOP5 SAMHD1	Homo sapiens (human)
Transport of Mature mRNA derived from an Intron-Containing Transcript	ATP-dependent RNA helicase DDX39A Aladin Chromatin target of PRMT1 protein E3 SUMO-protein ligase RanBP2 Eukaryotic initiation factor 4A-III Leucine zipper protein 4 NTF2-related export protein 1 Nuclear RNA export factor 1 Nuclear RNA export factor 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear envelope pore membrane protein POM 121 Nuclear envelope pore membrane protein POM 121C Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup155 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup93 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoporin Nup37 Nucleoporin Nup43 Nucleoporin p54 Nucleoprotein TPR Polymerase delta-interacting protein 3 Pre-mRNA-processing factor 17 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 Pre-mRNA-splicing factor SLU7 Protein CASC3 Protein SEC13 homolog Protein mago nashi homolog 2 Protein mago nashi homolog RNA-binding protein 8A RNA-binding protein with serine-rich domain 1 Regulator of nonsense transcripts 3B SAP domain-containing ribonucleoprotein Serine/arginine repetitive matrix protein 1 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 9 Spliceosome RNA helicase DDX39B Splicing factor U2AF 26 kDa subunit Splicing factor U2AF 35 kDa subunit Splicing factor U2AF 65 kDa subunit THO complex subunit 1 THO complex subunit 2 THO complex subunit 3 THO complex subunit 4 THO complex subunit 5 THO complex subunit 6 THO complex subunit 7 UAP56-interacting factor Zinc finger CCCH domain-containing protein 11A mRNA export factor GLE1 mRNA export factor RAE1	A8CG34 O00148 O15234 O15504 O60508 O75152 O75694 O95391 P12270 P26368 P35658 P37198 P38919 P49790 P49792 P52298 P55735 P57740 P61326 P78406 P82979 P84103 Q01081 Q01130 Q05519 Q07955 Q08170 Q09161 Q12769 Q13242 Q13243 Q13247 Q13769 Q13838 Q15287 Q16629 Q53GS7 Q5SRE5 Q6I9Y2 Q7Z3B4 Q86V81 Q86W42 Q8IYB3 Q8N1F7 Q8NFH3 Q8NFH4 Q8NFH5 Q8NI27 Q8TEM1 Q8WU68 Q8WUM0 Q92620 Q92621 Q96A72 Q96FV9 Q96HA1 Q96J01 Q96QD9 Q99567 Q9BTX1 Q9BW27 Q9BY77 Q9BZI7 Q9GZY0 Q9NRG9 Q9P127 Q9UBU9 Q9UKK6 Q9UKX7 Q9Y3Y2 Q9Y5S9	AAAS ADRACALA ALY ALYREF ASF BAT1 BEF C1orf77 C22orf19 C7orf14 CAIN CAN CASC3 CBP20 CBP80 CDC40 CG1 CHTOP CXorf3 D3S1231E DDX38 DDX39 DDX39A DDX39B DDX48 DHX38 EHB3 EIF4A3 FOP FYTTD1 GLE1 GLE1L HCC1 HPR1 HRS KIAA0023 KIAA0095 KIAA0111 KIAA0169 KIAA0197 KIAA0224 KIAA0225 KIAA0618 KIAA0663 KIAA0791 KIAA0906 KIAA0983 KIAA1649 LDC2 LUZP4 MAGOH MAGOH2 MAGOHA MAGOHB MLN51 MP44 MRNP41 NCBP NCBP1 NCBP2 NDC1 NIF3L1BP1 NPAP60L NUP107 NUP120 NUP121 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP358 NUP37 NUP42 NUP43 NUP50 NUP53 NUP54 NUP62 NUP75 NUP85 NUP88 NUP93 NUPL2 NXF1 NXF2 NXF2B NXT1 PCNT1 PDIP46 POLDIP3 POM121 POM121A POM121C PRP16 PRP17 PRPF17 RAE1 RANBP2 RBM8 RBM8A RENT3B RNPS1 SARNP SEC13 SEC13A SEC13L1 SEC13R SF2 SF2P33 SFRS1 SFRS11 SFRS2 SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SLU7 SRM160 SRP20 SRP30C SRP40 SRP55 SRP75 SRRM1 SRSF1 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF9 TAP TAPL2 THOC1 THOC2 THOC3 THOC4 THOC5 THOC6 THOC7 TMEM48 TPR U2AF1 U2AF1-RS3 U2AF1L3 U2AF1L4 U2AF2 U2AF35 U2AF65 U2AFBP UAP56 UIF UPF3B UPF3X WDR58 ZC3H11A ZC3HDC11A	Homo sapiens (human)
RAF/MAP kinase cascade	Alpha-actinin-2 Amphiregulin Angiopoietin-1 receptor Angiopoietin-1 Artemin Astrocytic phosphoprotein PEA-15 Beta-klotho Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Cytokine receptor common subunit beta Cytokine receptor common subunit gamma Disks large homolog 1 Disks large homolog 2 Disks large homolog 3 Disks large homolog 4 Epidermal growth factor receptor Epigen Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 19 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fms-related tyrosine kinase 3 ligand Focal adhesion kinase 1 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GDNF family receptor alpha-3 GDNF family receptor alpha-4 GTPase HRas GTPase NRas Glial cell line-derived neurotrophic factor Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor ionotropic, NMDA 2D Granulocyte-macrophage colony-stimulating factor receptor subunit alpha Granulocyte-macrophage colony-stimulating factor Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-3 receptor subunit alpha Interleukin-3 Interleukin-5 receptor subunit alpha Interleukin-5 Leucine-rich repeat-containing protein 7 Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Neural cell adhesion molecule 1 Neurofilament light polypeptide Neurturin Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Pro-neuregulin-2, membrane-bound isoform Pro-neuregulin-3, membrane-bound isoform Pro-neuregulin-4, membrane-bound isoform Probetacellulin Proepiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase receptor Ret Protransforming growth factor alpha RAS guanyl-releasing protein 1 RAS guanyl-releasing protein 4 Ral guanine nucleotide dissociation stimulator-like 1 Ral guanine nucleotide dissociation stimulator-like 2 Ral guanine nucleotide dissociation stimulator-like 3 Ral guanine nucleotide dissociation stimulator Ran-binding protein 9 Rap guanine nucleotide exchange factor 2 Ras guanyl-releasing protein 3 Ras-GEF domain-containing family member 1A Ras-specific guanine nucleotide-releasing factor 1 Ras-specific guanine nucleotide-releasing factor 2 Receptor tyrosine-protein kinase erbB-2 Receptor-type tyrosine-protein kinase FLT3 Receptor-type tyrosine-protein phosphatase alpha SHC-transforming protein 1 SHC-transforming protein 2 SHC-transforming protein 3 Son of sevenless homolog 1 Spectrin alpha chain, erythrocytic 1 Spectrin alpha chain, non-erythrocytic 1 Spectrin beta chain, erythrocytic Spectrin beta chain, non-erythrocytic 1 Spectrin beta chain, non-erythrocytic 2 Spectrin beta chain, non-erythrocytic 4 Spectrin beta chain, non-erythrocytic 5 Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3	O00451 O00459 O14511 O14827 O14944 O15020 O15211 O15399 O15520 O43320 O43559 O60542 O60609 O60674 O76093 O95267 O95750 P00533 P01111 P01112 P01127 P01133 P01135 P01589 P02549 P04141 P04626 P05113 P05230 P06241 P07196 P07949 P08581 P08620 P08700 P09038 P09619 P0DP23 P10721 P10767 P11277 P11487 P13591 P14210 P14784 P15509 P15514 P16234 P18433 P21781 P22455 P23458 P26951 P27361 P27986 P28482 P29353 P31371 P31785 P32927 P35070 P35568 P35609 P36888 P39905 P42336 P42338 P49771 P52333 P56159 P56975 P60568 P78352 P98077 Q01082 Q01344 Q02297 Q02763 Q05397 Q05586 Q07889 Q12959 Q12967 Q13224 Q13554 Q13555 Q13557 Q13813 Q13972 Q15121 Q15389 Q15700 Q3MIN7 Q5T4W7 Q6UW88 Q86Z14 Q8IV61 Q8N9B8 Q8TDF6 Q8WU20 Q8WWG1 Q92529 Q92796 Q96NW7 Q96S59 Q99075 Q99748 Q9GZV9 Q9GZZ7 Q9H254 Q9HCT0 Q9NP95 Q9NRC6 Q9NZL6 Q9UQM7 Q9Y4G8 Q9Y4H2	ACTN2 ANGPT1 AREG AREGB ARTN BSPECV BTC CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CD135 CDC25 CDHF12 CDHR16 CSF2 CSF2R CSF2RA CSF2RB CSF2RY DLG1 DLG2 DLG3 DLG4 DTR DTS EGF EGFR EPGN ERBB ERBB1 ERBB2 EREG ERK1 ERK2 EVN FAK FAK1 FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR4 FLK2 FLT3 FLT3LG FRS2 FRS3 FYN GDNF GDNFRA GDNFRB GFRA1 GFRA2 GFRA3 GFRA4 GGF GMCSF GNRP GRB1 GRF1 GRF2 GRIN1 GRIN2B GRIN2D GRP3 GluN2D HBEGF HEGFL HER1 HER2 HGF HGL HPTA HRAS HRAS1 HRGA HST HST2 HSTF1 HSTF2 HUBSPECV HUSPECV HYPF IL15RB IL2 IL2RA IL2RB IL2RG IL3 IL3R IL3RA IL3RB IL5 IL5R IL5RA IL5RB INT2 IRS1 IRS2 JAK1 JAK1A JAK1B JAK2 JAK3 JTK2 KGF KIAA0003 KIAA0302 KIAA0313 KIAA0846 KIAA0959 KIAA0968 KIAA1232 KIAA1308 KIAA1365 KIAA1642 KIT KLB KS3 LAP1 LRRC7 MAPK1 MAPK3 MET MLN19 NCAM NCAM1 NDF NEAS NEFL NEU NF68 NFL NGL NMDAR1 NMDAR2B NMDAR2D NRAPGEP NRAS NRG1 NRG2 NRG3 NRG4 NRTN NSHC NTAK PDGF2 PDGFB PDGFR PDGFR1 PDGFR2 PDGFRA PDGFRB PDZGEF1 PEA15 PIK3C1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKM1 PRKM2 PRKM3 PSD95 PSPN PTC PTK2 PTPA PTPRA PTPRL2 RAB2L RALGDS RANBP9 RANBPM RAPGEF2 RASGEF1A RASGRF1 RASGRF2 RASGRP RASGRP1 RASGRP3 RASGRP4 RET RETL1 RETL2 RGF RGL RGL1 RGL2 RGL3 RHEPDGFRA SCA5 SCFR SCK SDGF SHC SHC1 SHC2 SHC3 SHCA SHCB SHCC SIS SMDF SOS1 SPTA SPTA1 SPTA2 SPTAN1 SPTB SPTB1 SPTB2 SPTBN1 SPTBN2 SPTBN3 SPTBN4 SPTBN5 STK1 TEK TGFA TIE2 TKF TRNR1 TRNR2 VMCM VMCM1	Homo sapiens (human)
Signaling by moderate kinase activity BRAF mutants	14-3-3 protein beta/alpha Amyloid beta A4 precursor protein-binding family B member 1-interacting protein BRCA1-associated protein Beta-arrestin-1 Beta-arrestin-2 Calcium/calmodulin-dependent protein kinase type II subunit alpha Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calcium/calmodulin-dependent protein kinase type II subunit gamma Calmodulin-1 Connector enhancer of kinase suppressor of ras 1 Connector enhancer of kinase suppressor of ras 2 Dual specificity mitogen-activated protein kinase kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin GTPase HRas GTPase KRas GTPase NRas Integrin alpha-IIb Integrin beta-3 Kinase suppressor of Ras 1 Kinase suppressor of Ras 2 MAP/microtubule affinity-regulating kinase 3 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase kinase kinase 11 Phosphatidylethanolamine-binding protein 1 Prohibitin 1 Proto-oncogene tyrosine-protein kinase Src RAF proto-oncogene serine/threonine-protein kinase Ras GTPase-activating-like protein IQGAP1 Ras-related protein Rap-1A Ras-related protein Rap-1b Serine/threonine-protein kinase A-Raf Serine/threonine-protein kinase B-raf Talin-1 Tyrosine-protein kinase CSK Tyrosine-protein kinase JAK2 Vinculin von Willebrand factor	O60674 P01111 P01112 P01116 P02671 P02675 P02679 P02751 P04049 P04275 P05106 P08514 P0DP23 P10398 P12931 P15056 P18206 P27361 P27448 P28482 P30086 P31946 P32121 P35232 P36507 P41240 P46940 P49407 P61224 P62834 Q02750 Q13554 Q13555 Q13557 Q16584 Q6VAB6 Q7Z569 Q7Z5R6 Q8IVT5 Q8WXI2 Q969H4 Q9UQM7 Q9Y490	APBB1IP ARAF ARAF1 ARB2 ARR1 ARR2 ARRB1 ARRB2 BRAF BRAF1 BRAP CALM CALM1 CAM CAM1 CAM2 CAMK CAMK-II CAMK2 CAMK2A CAMK2B CAMK2D CAMK2G CAMKA CAMKB CAMKD CAMKG CNK1 CNK2 CNKSR1 CNKSR2 CSK CTAK1 EMK2 ERK1 ERK2 F8VWF FGA FGB FGG FN FN1 GP2B GP3A HRAS HRAS1 IQGAP1 ITGA2B ITGAB ITGB3 JAK2 KIAA0051 KIAA0902 KIAA0968 KIAA1027 KRAS KRAS2 KREV1 KSR KSR1 KSR2 MAP2K1 MAP2K2 MAP3K11 MAPK1 MAPK3 MARK3 MEK1 MEK2 MKK2 MLK3 NRAS PBP PEBP PEBP1 PHB PHB1 PKS PKS2 PREL1 PRKM1 PRKM2 PRKM3 PRKMK1 PRKMK2 PTK1 RAF RAF1 RAFB1 RAP1A RAP1B RARP1 RASK2 RIAM RNF52 SPRK SRC SRC1 TLN TLN1 VCL VWF YWHAB	Homo sapiens (human)
Synthesis of IP2, IP, and Ins in the cytosol	Inositol monophosphatase 1 Inositol monophosphatase 2 Inositol oxygenase Inositol polyphosphate 1-phosphatase Inositol polyphosphate 4-phosphatase type II Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase A Inositol-3-phosphate synthase 1 Myotubularin-related protein 9 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Phosphatidylinositol-3-phosphate phosphatase MTMR7 Synaptojanin-1 Type II inositol 1,4,5-trisphosphate 5-phosphatase	O14732 O15327 O43426 P29218 P32019 P49441 Q01968 Q14642 Q15735 Q96PE3 Q96QG7 Q9NPH2 Q9UGB7 Q9Y216	5PTASE ALDRL6 C8orf9 IMP.18P IMPA IMPA1 IMPA2 INO1 INPP1 INPP4A INPP4B INPP5A INPP5B INPP5J ISYNA1 KIAA0910 KSP32 MIOX MTMR7 MTMR8 MTMR9 OCRL OCRL1 OCRL2 PIB5PA PIPP RSOR SYNJ1	Homo sapiens (human)
Transport of organic anions	Monocarboxylate transporter 8 Solute carrier organic anion transporter family member 1A2 Solute carrier organic anion transporter family member 1B1 Solute carrier organic anion transporter family member 1B3 Solute carrier organic anion transporter family member 1C1 Solute carrier organic anion transporter family member 2A1 Solute carrier organic anion transporter family member 2B1 Solute carrier organic anion transporter family member 4A1 Solute carrier organic anion transporter family member 4C1 Vasopressin-neurophysin 2-copeptin	O94956 P01185 P36021 P46721 Q6ZQN7 Q92959 Q96BD0 Q9NPD5 Q9NYB5 Q9Y6L6	ARVP AVP KIAA0880 LST1 LST2 MCT7 MCT8 OATP OATP1 OATP14 OATP1A2 OATP1B1 OATP1B3 OATP1C1 OATP2 OATP2A1 OATP2B1 OATP4A1 OATP4C1 OATP8 OATPB OATPC OATPE OATPF OATPX SLC16A2 SLC21A12 SLC21A14 SLC21A2 SLC21A20 SLC21A3 SLC21A6 SLC21A8 SLC21A9 SLCO1A2 SLCO1B1 SLCO1B3 SLCO1C1 SLCO2A1 SLCO2B1 SLCO4A1 SLCO4C1 VP XPCT	Homo sapiens (human)
Separation of Sister Chromatids	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit 7 Anaphase-promoting complex subunit CDC26 Aurora kinase B B9 domain-containing protein 2 Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain-containing linker protein 1 CLIP-associating protein 1 CLIP-associating protein 2 Cell division cycle protein 16 homolog Cell division cycle protein 20 homolog Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Centromere protein C Centromere protein F Centromere protein H Centromere protein I Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein P Centromere protein Q Centromere protein R Centromere protein S Centromere protein T Centromere protein U Centromere-associated protein E Centromere/kinetochore protein zw10 homolog Cohesin subunit SA-1 Cohesin subunit SA-2 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic dynein 1 light intermediate chain 1 Cytoplasmic dynein 1 light intermediate chain 2 Cytoskeleton-associated protein 5 DNA excision repair protein ERCC-6-like Double-strand-break repair protein rad21 homolog Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic E3 SUMO-protein ligase RanBP2 Exportin-1 Histone H3-like centromeric protein A Inner centromere protein Kinesin-like protein KIF18A Kinesin-like protein KIF2A Kinesin-like protein KIF2B Kinesin-like protein KIF2C Kinetochore protein NDC80 homolog Kinetochore protein Nuf2 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Kinetochore-associated protein 1 Kinetochore-associated protein DSN1 homolog Kinetochore-associated protein NSL1 homolog Microtubule-associated protein RP/EB family member 1 Mitotic checkpoint protein BUB3 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Mitotic checkpoint serine/threonine-protein kinase BUB1 Mitotic spindle assembly checkpoint protein MAD1 Mitotic spindle assembly checkpoint protein MAD2A Nuclear distribution protein nudE homolog 1 Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup160 Nuclear pore complex protein Nup85 Nucleoporin Nup37 Nucleoporin Nup43 Platelet-activating factor acetylhydrolase IB subunit beta Polyamine-modulated factor 1 Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein ELYS Protein MIS12 homolog Protein RCC2 Protein SEC13 homolog Protein Spindly Protein zwilch homolog Ran GTPase-activating protein 1 SKA complex subunit 1 Securin Separin Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase TAO1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Sister chromatid cohesion protein PDS5 homolog A Sister chromatid cohesion protein PDS5 homolog B Small ribosomal subunit protein eS27 Sororin Spindle and kinetochore-associated protein 2 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein 3 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 E1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Wings apart-like protein homolog ZW10 interactor	O00139 O00231 O00232 O00487 O00762 O14576 O14777 O14818 O14980 O15392 O43237 O43242 O43264 O43683 O43684 O60216 O60566 O75122 O95229 O95997 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P30153 P30154 P30260 P30622 P35998 P36873 P42677 P43034 P43686 P46060 P48556 P49450 P49454 P49720 P49721 P49792 P50748 P51665 P51668 P51965 P53350 P55735 P57740 P60006 P60896 P60900 P62191 P62195 P62333 P62714 P62979 P62987 P63167 P67775 Q02224 Q03188 Q12769 Q12834 Q13042 Q13200 Q13257 Q13352 Q13362 Q13409 Q14008 Q14204 Q14674 Q14683 Q14738 Q15008 Q15172 Q15173 Q15691 Q16186 Q16537 Q16763 Q29RF7 Q2NKX8 Q53HL2 Q562F6 Q5FBB7 Q6IPU0 Q6P1K2 Q71F23 Q7L2Z9 Q7L7X3 Q7Z460 Q7Z5K2 Q8N0S6 Q8N2Z9 Q8N3U4 Q8N4N8 Q8NBT2 Q8NFH3 Q8NFH4 Q8NG31 Q8NHZ8 Q8NI77 Q8WUM0 Q8WVK7 Q8WVM7 Q8WYP5 Q92674 Q96BD8 Q96BT3 Q96DE5 Q96EA4 Q96FF9 Q96FJ2 Q96GD4 Q96H22 Q96IY1 Q99436 Q99460 Q99661 Q9BPU9 Q9BS16 Q9BU64 Q9BW27 Q9BZD4 Q9GZM8 Q9H081 Q9H1A4 Q9H3R5 Q9H410 Q9H900 Q9HBM1 Q9NQS7 Q9NSP4 Q9NTI5 Q9NXR1 Q9NYG5 Q9P258 Q9UJX2 Q9UJX3 Q9UJX4 Q9UJX5 Q9UJX6 Q9UM13 Q9UNM6 Q9UQE7 Q9Y266 Q9Y6D9 Q9Y6G9	ADRM1 AHCTF1 AIK2 AIM1 AIRK2 ANAPC1 ANAPC10 ANAPC11 ANAPC12 ANAPC15 ANAPC16 ANAPC2 ANAPC3 ANAPC4 ANAPC5 ANAPC6 ANAPC7 ANAPC8 APC10 APC2 APC4 APC5 APC7 API4 APITD1 APRIN ARK2 AS3 AURKB B9D2 BAM BIRC5 BMH BUB1 BUB1B BUB1L BUB3 BUBR1 C10orf104 C11orf51 C16orf56 C16orf60 C18orf24 C1orf155 C1orf48 C20orf172 C22orf18 C6orf139 C7orf76 C9orf17 CASC5 CCDC99 CDC16 CDC20 CDC23 CDC26 CDC27 CDCA1 CDCA5 CDCA8 CENP-27 CENPA CENPC CENPC1 CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPN CENPO CENPP CENPQ CENPR CENPS CENPT CENPU CKAP5 CLASP1 CLASP2 CLIP1 CRM1 CSPG6 CYLN1 D0S1430E D17S978E D3S1231E DHC1 DLC1 DLC2 DNCH1 DNCI1 DNCI2 DNCIC1 DNCIC2 DNCL DNCL1 DNCLC1 DNCLI1 DNCLI2 DNECL DSN1 DSS1 DXS423E DYHC DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 E2EPF EAP1 ELYS EOPA ERCC6L ESP1 ESPL1 FAAP16 FAM33A FOE FSHPRH1 GP110 HC2 HC3 HC8 HC9 HDLC1 HEC HEC1 HR21 HSPC IAP4 ICEN19 ICEN22 ICEN24 ICEN32 ICEN33 ICEN35 ICEN36 ICEN37 ICEN39 ICEN7 INCENP ITGB3BP KIAA0044 KIAA0078 KIAA0097 KIAA0107 KIAA0165 KIAA0166 KIAA0178 KIAA0197 KIAA0261 KIAA0325 KIAA0622 KIAA0627 KIAA0648 KIAA0979 KIAA1361 KIAA1406 KIAA1470 KIAA1570 KIAA1835 KIF18A KIF2 KIF2A KIF2B KIF2C KLIP1 KNL1 KNS2 KNSL6 KNTC1 KNTC2 LIC2 LIS1 LMPX LMPY LRPR1 MAD1 MAD1L1 MAD2 MAD2L1 MAD3L MAP3K16 MAPRE1 MARKK MAST1 MB1 MCM21R MDCR MDS MHF1 MIP224 MIS12 MIS13 MITAP1 MKSR2 MLF1IP MOV34L MPS1 MSS1 NDC80 NDE1 NDEL1 NRIF3 NSL1 NU NUDC NUDE NUDEL NUF2 NUF2R NUP107 NUP120 NUP133 NUP160 NUP358 NUP37 NUP43 NUP75 NUP85 NXP1 PAFAH1B1 PAFAHA PANE1 PBIP1 PCNT1 PDS5 PDS5A PDS5B PESCRG3 PFAAP4 PICH PLK PLK1 PMF1 POH1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 PTTG PTTG1 RAD21 RANBP2 RANGAP1 RCC2 ROD RPS27 RPS27A RSN SA1 SA2 SB1.8 SCC1 SCC3 SD SEC13 SEC13A SEC13L1 SEC13R SEM1 SFT SGO1 SGO2 SGOL1 SGOL2 SHFDG1 SHFM1 SKA1 SKA2 SMC1 SMC1A SMC1L1 SMC3 SMC3L1 SPBC24 SPBC25 SPC24 SPC25 SPDL1 SSK1 STAG1 STAG2 STK1 STK12 STK5 SUG1 SUG2 TAOK1 TBP1 TBP7 TD60 TMBS62 TRAP2 TSG24 TUTR1 TXBP181 UBA52 UBA80 UBB UBC UBC5A UBCEP1 UBCEP2 UBCH10 UBCH5 UBCH5A UBCH6 UBE2C UBE2D1 UBE2E1 UBE2S WAPAL WAPL X XPO1 Y Z ZW10 ZWILCH ZWINT	Homo sapiens (human)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Collagen alpha-2(I) chain Cyclin-C Cyclin-K Cyclin-T1 Cyclin-T2 Cyclin-dependent kinase 4 inhibitor B Cyclin-dependent kinase 8 Cyclin-dependent kinase 9 E3 ubiquitin-protein ligase Arkadia Furin Histone acetyltransferase p300 Histone deacetylase 1 Homeobox protein TGIF1 Homeobox protein TGIF2 Menin Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog 7 Myc proto-oncogene protein Plasminogen activator inhibitor 1 Polyubiquitin-B Polyubiquitin-C Retinoblastoma-like protein 1 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F4 Transcription factor E2F5 Transcription factor JunB Transcription factor Sp1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain-containing transcription regulator protein 1 Y-box-binding protein 1	O00255 O15105 O60563 O60583 O75909 P01106 P05121 P08047 P08123 P09958 P0CG47 P0CG48 P17275 P24863 P27361 P28482 P28749 P42772 P49336 P50750 P62979 P62987 P67809 P84022 Q09472 Q13485 Q13547 Q14186 Q14188 Q15329 Q15583 Q15796 Q16254 Q6ZNA4 Q9GZN2 Q9GZV5	BHLHE39 CCNC CCNK CCNT1 CCNT2 CDC2L4 CDK8 CDK9 CDKN2B COL1A2 CPR4 DP1 DP2 DPC4 E2F4 E2F5 EP300 ERK1 ERK2 FUR FURIN HDAC1 JUNB MADH2 MADH3 MADH4 MADH7 MADH8 MADR2 MAPK1 MAPK3 MEN1 MTS2 MYC NSEP1 P300 PACE PAI1 PCSK3 PLANH1 PRKM1 PRKM2 PRKM3 RBL1 RNF111 RPD3L1 RPS27A SCG2 SERPINE1 SMAD2 SMAD3 SMAD4 SMAD7 SP1 TAK TAZ TFDP1 TFDP2 TGIF TGIF1 TGIF2 TSFP1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 WWTR1 YB1 YBX1	Homo sapiens (human)
Hedgehog ligand biogenesis	26S proteasome complex subunit SEM1 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Derlin-2 Desert hedgehog protein E3 ubiquitin-protein ligase synoviolin Endoplasmic reticulum lectin 1 Indian hedgehog protein Polyubiquitin-B Polyubiquitin-C Proteasomal ubiquitin receptor ADRM1 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Protein OS-9 Protein disulfide-isomerase Protein sel-1 homolog 1 Protein-cysteine N-palmitoyltransferase HHAT Sonic hedgehog protein Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O00231 O00232 O00487 O14818 O43242 O43323 P07237 P0CG47 P0CG48 P17980 P20618 P25786 P25787 P25788 P25789 P28066 P28070 P28072 P28074 P35998 P43686 P48556 P49720 P49721 P51665 P55072 P60896 P60900 P62191 P62195 P62333 P62979 P62987 Q13200 Q13438 Q14623 Q15008 Q15465 Q16186 Q5VTY9 Q86TM6 Q96DZ1 Q99436 Q99460 Q9GZP9 Q9UBV2 Q9UNM6	ADRM1 C2orf30 C7orf76 DER2 DERL2 DHH DSS1 ERBA2L ERLEC1 FLANA GP110 HC2 HC3 HC8 HC9 HEL-220 HEL-S-70 HHAT HRD1 HSPC IHH KIAA0107 KIAA1810 LMPX LMPY MART2 MB1 MIP224 MOV34L MSS1 NU OS9 P4HB PDI PDIA1 PFAAP4 PO4DB POH1 PROS26 PROS27 PROS30 PSC2 PSC3 PSC5 PSC8 PSC9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD6 PSMD7 PSMD8 RPS27A SEL1L SEM1 SHFDG1 SHFM1 SHH SKI1 SUG1 SUG2 SYVN1 TBP1 TBP7 TRAP2 TSA305 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP X XTP3TPB Y Z	Homo sapiens (human)
Sensory perception of sweet, bitter, and umami (glutamate) taste	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 Calcium homeostasis modulator protein 1 Calcium homeostasis modulator protein 3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 4 Sodium channel protein type 2 subunit alpha Sodium channel protein type 3 subunit alpha Sodium channel protein type 9 subunit alpha Sodium channel regulatory subunit beta-1 Sodium channel regulatory subunit beta-2 Sodium channel subunit beta-4 Taste receptor type 1 member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 10 Taste receptor type 2 member 13 Taste receptor type 2 member 14 Taste receptor type 2 member 16 Taste receptor type 2 member 1 Taste receptor type 2 member 20 Taste receptor type 2 member 30 Taste receptor type 2 member 31 Taste receptor type 2 member 38 Taste receptor type 2 member 39 Taste receptor type 2 member 3 Taste receptor type 2 member 40 Taste receptor type 2 member 41 Taste receptor type 2 member 43 Taste receptor type 2 member 46 Taste receptor type 2 member 4 Taste receptor type 2 member 50 Taste receptor type 2 member 5 Taste receptor type 2 member 7 Taste receptor type 2 member 8 Transient receptor potential cation channel subfamily M member 4 Transient receptor potential cation channel subfamily M member 5	A8MTJ3 O60939 P16520 P59533 P59534 P59535 P59536 P59537 P59538 P59540 P59541 P59543 P59544 P62873 Q00722 Q07699 Q13255 Q14573 Q14833 Q15858 Q7RTX0 Q7RTX1 Q86XJ0 Q8IU99 Q8IWT1 Q8TD43 Q8TE23 Q99250 Q9NY46 Q9NYV7 Q9NYV8 Q9NYV9 Q9NYW0 Q9NYW2 Q9NYW3 Q9NYW4 Q9NYW5 Q9NYW6 Q9NYW7 Q9NZQ8 Q9P2W3	CALHM1 CALHM3 FAM26A FAM26C GNAT3 GNB1 GNB3 GNG13 GPR60 GPR70 GPR71 GPRC1A GPRC1D GRM1 GRM4 HBA ITPR3 KIAA1356 LTRPC4 LTRPC5 MGLUR1 MGLUR4 MTR1 NAC2 NAC3 NENA PLCB2 PTC SCN1B SCN2A SCN2A1 SCN2A2 SCN2B SCN3A SCN4B SCN9A T1R1 T1R2 T1R3 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R20 TAS2R3 TAS2R30 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R43 TAS2R44 TAS2R46 TAS2R47 TAS2R49 TAS2R5 TAS2R50 TAS2R7 TAS2R8 TR1 TR2 TR3 TRPM4 TRPM5	Homo sapiens (human)	G58161NS
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIE subunit 1 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 TATA-binding protein-associated factor 2N TATA-box-binding protein Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor TFIID subunit 1-like Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 11 Transcription initiation factor TFIID subunit 12 Transcription initiation factor TFIID subunit 13 Transcription initiation factor TFIID subunit 1 Transcription initiation factor TFIID subunit 2 Transcription initiation factor TFIID subunit 3 Transcription initiation factor TFIID subunit 4 Transcription initiation factor TFIID subunit 4B Transcription initiation factor TFIID subunit 5 Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 7-like Transcription initiation factor TFIID subunit 7 Transcription initiation factor TFIID subunit 9 Transcription initiation factor TFIID subunit 9B	O00268 O15514 P13984 P18074 P19387 P19388 P19447 P20226 P21675 P24928 P29083 P29084 P30876 P32780 P35269 P36954 P49848 P50613 P51946 P51948 P52434 P52435 P52655 P52657 P53803 P61218 P62487 P62875 Q00403 Q12962 Q13888 Q13889 Q15542 Q15543 Q15544 Q15545 Q16514 Q16594 Q5H9L4 Q5VWG9 Q6P1X5 Q6ZYL4 Q8IZX4 Q92750 Q92759 Q92804 Q9HBM6	BA2R BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCG1 CCGS CCNH CDK7 CDKN7 CIF150 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2D1 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 MAT1 MNAT1 MO15 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RBP56 RNF66 RPB7 STK1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1L TAF2 TAF2A TAF2B TAF2C TAF2C1 TAF2C2 TAF2D TAF2E TAF2F TAF2G TAF2H TAF2I TAF2J TAF2K TAF2N TAF2Q TAF3 TAF4 TAF4A TAF4B TAF5 TAF6 TAF7 TAF7L TAF9 TAF9B TAF9L TAFII105 TAFII130 TAFII135 TAFII18 TAFII20 TAFII30 TAFII31 TAFII55 TAFII70 TBP TF2A1 TF2A2 TF2B TF2D TF2E1 TF2E2 TFIIB TFIID TTDA XPB XPBC XPD XPDC	Homo sapiens (human)
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)	Sodium-dependent dopamine transporter	Q01959	DAT1 SLC6A3	Homo sapiens (human)
Defective ABCB6 causes MCOPCB7	ATP-binding cassette sub-family B member 6	Q9NP58	ABCB6 MTABC3 PRP UMAT	Homo sapiens (human)
MPS IV - Morquio syndrome B	Beta-galactosidase	P16278	ELNR1 GLB1	Homo sapiens (human)	G82768YB
Gluconeogenesis	Alpha-enolase Beta-enolase Enolase 4 Fructose-1,6-bisphosphatase 1 Fructose-1,6-bisphosphatase isozyme 2 Fructose-bisphosphate aldolase A Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase C Gamma-enolase Glucose-6-phosphatase 2 Glucose-6-phosphatase 3 Glucose-6-phosphatase catalytic subunit 1 Glucose-6-phosphate exchanger SLC37A1 Glucose-6-phosphate exchanger SLC37A4 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase, testis-specific Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase [GTP], mitochondrial Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate kinase 1 Phosphoglycerate kinase 2 Phosphoglycerate mutase 1 Phosphoglycerate mutase 2 Pyruvate carboxylase, mitochondrial Triosephosphate isomerase	A6NNW6 O00757 O14556 O43826 P00558 P04075 P04406 P05062 P06733 P06744 P07205 P09104 P09467 P09972 P11498 P13929 P15259 P18669 P35558 P35575 P57057 P60174 Q16822 Q9BUM1 Q9NQR9	ALDA ALDB ALDC ALDOA ALDOB ALDOC C10orf134 ENO1 ENO1L1 ENO2 ENO3 ENO4 FBP FBP1 FBP2 G3PP G6PC G6PC1 G6PC2 G6PC3 G6PT G6PT1 GAPD GAPD2 GAPDH GAPDH2 GAPDHS GAPDS GPI IGRP MBPB1 MPB1 PC PCK1 PCK2 PEPCK1 PEPCK2 PGAM1 PGAM2 PGAMA PGAMM PGK1 PGK2 PGKA PGKB SLC37A1 SLC37A4 TPI TPI1 UGRP	Homo sapiens (human)	G58161NS
NF-kB is activated and signals survival	Beta-nerve growth factor Inhibitor of nuclear factor kappa-B kinase subunit beta Interleukin-1 receptor-associated kinase 1 NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Polyubiquitin-C Sequestosome-1 TNF receptor-associated factor 6 Transcription factor p65 Tumor necrosis factor receptor superfamily member 16 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O14920 P01138 P08138 P0CG47 P0CG48 P19838 P25963 P51617 P62979 P62987 Q04206 Q13501 Q9Y4K3	IKBA IKBKB IKKB IRAK IRAK1 MAD3 NFKB1 NFKB3 NFKBI NFKBIA NGF NGFB NGFR ORCA OSIL RELA RNF85 RPS27A SQSTM1 TNFRSF16 TRAF6 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Homo sapiens (human)
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	Cyclin-A2 Cyclin-dependent kinase 1 Histone deacetylase 1 Histone-binding protein RBBP4 Myb-related protein B Protein lin-37 homolog Protein lin-52 homolog Protein lin-54 homolog Protein lin-9 homolog Retinoblastoma-like protein 1 Retinoblastoma-like protein 2 Transcription factor Dp-1 Transcription factor Dp-2 Transcription factor E2F1 Transcription factor E2F4 Transcription factor E2F5	P06493 P10244 P20248 P28749 Q01094 Q08999 Q09028 Q13547 Q14186 Q14188 Q15329 Q16254 Q52LA3 Q5TKA1 Q6MZP7 Q96GY3	BARA BMYB C14orf46 CCN1 CCNA CCNA2 CDC2 CDC28A CDK1 CDKN1 CXCDC1 DP1 DP2 E2F1 E2F4 E2F5 HDAC1 KIAA2037 LIN37 LIN52 LIN54 LIN9 MYBL2 P34CDC2 RB2 RBAP48 RBBP3 RBBP4 RBL1 RBL2 RPD3L1 TFDP1 TFDP2 TGS	Homo sapiens (human)
Regulation of commissural axon pathfinding by SLIT and ROBO	Netrin receptor DCC Netrin-1 Protein kinase C-binding protein NELL2 Proto-oncogene tyrosine-protein kinase Src Roundabout homolog 1 Roundabout homolog 2 Slit homolog 1 protein Slit homolog 2 protein Slit homolog 3 protein	O75093 O75094 O94813 O95631 P12931 P43146 Q99435 Q9HCK4 Q9Y6N7	DCC DUTT1 IGDCC1 KIAA0813 KIAA0814 KIAA1568 MEGF4 MEGF5 NELL2 NRP2 NTN1 NTN1L ROBO1 ROBO2 SLIL1 SLIL2 SLIL3 SLIT1 SLIT2 SLIT3 SRC SRC1	Homo sapiens (human)
MET activates RAS signaling	GTPase HRas GTPase NRas Hepatocyte growth factor receptor Hepatocyte growth factor Mucin-20 Ran-binding protein 10 Ran-binding protein 9 Son of sevenless homolog 1	P01111 P01112 P08581 P14210 Q07889 Q6VN20 Q8N307 Q96S59	HGF HPTA HRAS HRAS1 KIAA1359 KIAA1464 MET MUC20 NRAS RANBP10 RANBP9 RANBPM SOS1	Homo sapiens (human)

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