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GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB) and Alliance of Genome Resources is integrated into one list.

Source	Last Updated
Alliance of Genome Resources	October 9, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Displaying entries **9126 - 9150** of **15957** in total

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Disease ID ▲	Disease Name	Gene Symbol	Gene ID	Organism	Source
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	A2m Acadvl Ace Ache Adam10 Adam17 Adam2 Adra1a Adrb3 Agt Agtr1a Agtr1b Aldh2 Ank3 Aoc3 Apod App Aqp4 Atf2 Atp5f1a Atp5f1d Atp5mg Atp5po Atp7a Bace1 Bace2 Bad Bdnf C3 C5ar1 Camk2a Ccr5 Cd40lg Cdk5 Cebpb Cftr Chrna4 Chrna7 Clu Cst3 Ctnnb1 Ctsd Ctss Dlst Dnm1 Dnm1l Drd2 Drd3 Drd5 Dync1h1 Egf Elk1 Eno1 Epo Esr1 Esr2 Fas Fgfr1 Gapdh Gapdhs Gdnf Glud1 Grin1 Grin2a Grin2b Grn Gsk3b Gsto2 Hadha Hadhb Hfe Hivep2 Hmgcr Hsd17b10 Hspa1a Hspd1 Htr1a Htr2a Icam1 Igf1r Igf2 Igfbp3 Il10 Il1a Il2 Il4 Ins1 Ins2 Irs1 Itpr1 Kcnc4 L1cam Ldlr Lep Lpl Lrp1 Lrpap1 Map2 Mme Mmp2 Mmp9 ND4 Ncam1 Ncstn Nefl Nefm Nfe2l2 Ngf Ngfr Nos1 Nos3 Notch3 Nrp1 Ntf3 Ntrk1 Ntrk2 Parp1 Pck1 Pdgfb Pik3r1 Plcd1 Pon1 Pon2 Pon3 Ppara Pparg Ppargc1a Prkcb Ptgs2 Reg1a Reln Sell Selp Serpine2 Slc18a3 Slc25a4 Slc2a1 Slc2a3 Slc8a1 Slc8a2 Slc8a3 Snap91 Snca Sncb Sncg Sod2 Sorl1 Syp Tlr4 Tm2d2 Tmed10 Tnf Tnfrsf1a Tnfrsf1b Ttr Uqcrc1 Vegfa Vim	113893 113959 114114 116562 116565 117029 140447 140448 140694 140908 156767 170670 171155 171293 192241 24153 24179 24180 24225 24232 24253 24255 24310 24318 24333 24335 24383 24399 24408 24409 24410 24472 24473 24483 24484 24493 24505 24506 24539 24586 24588 24590 24596 245965 24598 24600 246097 24628 246331 24655 24714 24718 24778 24787 24804 24835 24854 24856 24890 24941 25023 25054 25149 25195 25239 25262 25293 25302 25307 25313 25325 25363 25400 25453 25464 25467 25513 25551 25590 25591 25595 25608 25625 25645 25651 25664 25675 25718 25747 26201 287287 288227 289231 290833 29143 29199 29219 29238 29259 29260 29366 29392 29412 29473 29489 29527 29539 29595 29650 296851 29715 29721 299201 299858 300438 300652 300677 301011 309465 310738 312086 314436 361833 362282 50654 50687 54226 56761 56806 57027 59109 60422 63864 63868 64347 64639 65178 65262 66020 684516 79114 81638 81647 81686 81687 81737 81818 83516 83613 83619 83785 83817 84024 84027 84349 84353 84599 85333	Rattus norvegicus (Norway rat)	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	C02F5.13 C41D11.9 W01C8.5 W01F3.2 Y66D12A.21 abt-2 ace-1 ace-2 ace-3 acn-1 acr-15 acr-16 acr-7 adm-2 adm-4 aph-2 apl-1 asp-4 cpi-1 cri-2 daf-2 dop-1 dop-2 dop-4 eat-2 eef-1A.1 eef-1A.2 enol-1 gldi-2 gpd-1 gpd-3 gpd-4 lad-2 lev-9 lin-12 ncam-1 nep-11 nep-1 nep-2 parp-1 pkc-2 poml-1 poml-2 scav-2 scav-3 ser-5 skn-1 sph-1 srp-3 sup-17 timp-1 unc-29 unc-38 unc-63 vab-1 zmp-4	171782 171905 171999 172105 172150 172689 172703 172905 173685 173794 174116 174262 174423 174578 174603 174787 175072 175076 175410 175975 176282 176581 176673 176787 177078 177343 177372 177608 178672 179197 179199 179235 179347 179991 180351 180418 180601 180714 180780 180783 180836 181041 181044 181166 181444 181489 181706 183715 184572 187297 188090 188252 191602 266651 266823 3565859	Caenorhabditis elegans	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	A2m Abca1 Acadvl Ace Ache Adam10 Adam17 Adam2 Adam9 Adipoq Adra1a Adrb3 Ager Agtr1a Agtr1b Aifm1 Akap5 Aldh2 Ank2 Ank3 Anxa5 Aoc3 Apbb1 Aplp1 Aplp2 Apod App Aqp4 Ass1 Atf2 Atp5f1a Atp5mg Atp7a Bace1 Bace2 Bad Baiap2 Bax Bche Bdnf C1qb C2 C3 C5ar1 Camk2a Casp9 Cast Ccr5 Cd36 Cd40lg Cebpb Cftr Chrna4 Chrna7 Clock Clu Csnk1d Cst3 Ctnnb1 Ctsd Ctss Dbn1 Dlg4 Dlst Dnaja1 Dnaja2 Dnm1 Dnm1l Drd1 Drd2 Drd3 Drd4 Drd5 Dync1h1 Ece1 Eef1a2 Eef2 Egf Egr1 Eif2s1 Elk1 Eno1 Eno1b Ep300 Epha4 Ephx1 Epo Epor Esr1 Esr2 Fas Fgfr1 Gapdh Gapdhs Gcg Gdnf Glud1 Glul Gnas Grin1 Grin2a Grin2b Grn Gsk3b Gsr Gss Gsto1 Gsto2 H2-Eb1 Hadha Hfe Hivep2 Hivep3 Hmgcr Hnrnpa1 Hsf1 Hsp90aa1 Hspa1a Hspa9 Hspb1 Hspd1 Htr1a Htr2a Htr6 Icam1 Igf1r Igf2 Igfbp3 Ikbkb Il10 Il1a Il2 Il3 Il4 Il6ra Il6st Il7 Ins1 Ins2 Insr Irs1 Irs2 Itpr1 Kcnc4 Kcnma1 L1cam Ldlr Lep Lipc Lpl Lrp1 Lrpap1 Maob Map2 Mapk14 Mapt Mbl2 Mcm2 Mme Mmp2 Mmp9 Napb Ncam1 Ncstn Ndufa2 Ndufb8 Nectin2 Nefl Nefm Nfe2l2 Ngf Ngfr Nos3 Notch2 Notch3 Notch4 Nrp1 Ntf3 Ntrk1 Ntrk2 Pak1 Pck1 Pcsk1n Pdgfb Pik3r1 Pitrm1 Plcd1 Pon1 Pon2 Pon3 Ppara Pparg Ppargc1a Ppp1r9b Ppp2r2b Prkcb Psmc5 Ptgs1 Ptgs2 Ptpn5 Rcor1 Reg1 Reln Sell Selp Serpine2 Serpinf1 Slc25a4 Slc2a1 Slc2a3 Slc8a1 Slc8a2 Slc8a3 Snap91 Snca Sncb Sncg Sod1 Sod2 Sorl1 Sox13 Spint1 Stat3 Stox1 Syp Thbd Tlr4 Tm2d1 Tm2d2 Tm2d3 Tmed10 Tnf Tnfrsf1a Tnfrsf1b Tomm40 Ttr Uqcrc1 Vegfa Vim Vldlr	104069 104318 108100 109676 109731 110891 110893 11303 11370 11421 11423 11438 11441 11450 11487 11491 11495 11502 11549 11556 11596 11607 11608 11669 11735 11739 11747 11754 11785 11803 11804 11815 11820 11829 11898 11909 11946 11977 12015 12028 12038 12064 12260 12263 12266 12273 12322 12371 12380 12387 12491 12608 12638 12753 12759 12774 13010 13033 13040 13385 13424 13429 13488 13489 13490 13491 13492 13628 13629 13645 13653 13665 13712 13806 13838 13849 13856 13857 13982 13983 14102 14182 14433 14447 14526 14573 14645 14661 14683 14782 14810 14811 14812 14824 14854 14873 14969 15216 15273 15357 15382 15450 15499 15502 15507 15510 15519 15526 15550 15558 15565 15894 16001 16002 16009 16150 16153 16175 16183 16187 16189 16194 16195 16196 16333 16334 16337 16367 16438 16531 16656 16728 16835 16846 16956 16971 16976 17195 17216 17380 17390 17395 17756 17762 17957 17967 17991 18024 18039 18040 18049 18053 18127 18129 18131 18132 18186 18205 18211 18212 18479 18534 18591 18708 18751 18799 18979 19013 19016 19017 19184 19224 19225 19259 19294 193740 19692 19699 20317 20343 20344 20525 20527 20541 20616 20617 20618 20655 20656 20660 20668 20720 20732 20848 20977 216021 217124 217864 21824 21898 21926 21937 21938 21947 22139 22273 22339 22352 22359 230857 232345 23821 238276 26416 26926 269823 27425 30052 328572 330260 384783 433182 53333 56175 56320 56445 56637 59287 67264 68214 68581 68634 69617 69742 72930 74006 78920 94043 97212 99738	Mus musculus (house mouse)	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	ace ache cftr epoa fgfr1a gapdh gapdhs ins ngfb notch1a parp1 plcd1a pon1 slc18a3a slc18a3b tm2d1 tm2d2 tm2d3 vegfaa	100004455 100093710 100093711 114549 30262 30682 30705 30718 317743 394082 406367 436913 447803 555443 559080 559347 560788 565980 58133	Danio rerio (zebrafish)	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	A2M ABAT ABCA1 ACADVL ACE ACHE ADAM10 ADAM17 ADAM2 ADAM9 ADIPOQ ADRA1A ADRB3 AGER AGT AGTR1 AIFM1 AKR7A2 ALDH2 ALOX15 ANK2 ANXA5 AOC3 APBB1 APC APLP1 APLP2 APOA1 APOA4 APOD APOE APP AQP4 ASS1 ATF2 ATM ATP5F1A ATP7A ATR BACE1 BACE2 BAD BAIAP2 BARHL1 BAX BCHE BDNF BPTF C2 C3 C5AR1 CALML5 CAMK2A CAPN1 CASP6 CASP7 CASP9 CAST CCL5 CCR1 CCR5 CD36 CD40LG CDC42 CDK5 CDK7 CEBPB CFTR CHAT CHRNA4 CHRNA7 CLOCK CLU CTNNB1 CTSD CTSS CYP19A1 CYP46A1 CYP51A1 DBN1 DLST DNM1 DNM1L DRD1 DRD2 DRD3 DRD4 DRD5 DYNC1H1 E2F1 ECE1 EEF1A2 EEF2 EGF EGR1 EIF2AK2 EIF2S1 ELK1 ENO1 EP300 EPHA4 EPO EPOR ESR1 FADD FAS FGFR1 FOXO3 GAPDH GAPDHS GCG GDNF GLUD1 GLUL GNAS GRIN1 GRIN2A GRIN2B GRN GSK3B GSTO1 GSTO2 HADHA HADHB HBA1 HBA2 HFE HIF1A HIVEP1 HIVEP2 HIVEP3 HLA-DRB1 HMGCR HNRNPA1 HNRNPA2B1 HRAS HSD17B10 HSD17B3 HSD3B2 HSF1 HSP90AA1 HSPA1A HSPA1B HSPA9 HSPB1 HSPD1 HTR1A HTR2A ICAM1 IGF1R IGF2 IGFBP2 IGFBP3 IKBKB IL10 IL1A IL2 IL3 IL4 IL6 IL6R IL6ST IL7 INS INSR IREB2 IRS1 IRS2 ITPR1 KCNC4 KCNMA1 KLK6 L1CAM LDLR LEP LIPC LPA LPL LRP1 LRP8 LRPAP1 MAOA MAP2 MAPK14 MAPK9 MAPT MBL2 MCM2 MME MMP2 MMP9 MRE11 MT1E MT1H MT2A NBN NCAM1 NCSTN NDUFB8 NDUFS3 NECTIN2 NEFL NEFM NFE2L2 NGF NGFR NOS1 NOS2 NOS3 NOTCH4 NRG1 NRP1 NTF3 NTRK1 NTRK2 OPA1 PAK1 PARP1 PAWR PCK1 PCMT1 PCSK1N PDGFB PEBP1 PHACTR2 PITRM1 PLAU PLCB1 PLCD1 PLCG1 PON1 PON2 PON3 PPARA PPARG PPARGC1A PPP1R9B PSMC5 PTGS1 PTGS2 RCOR1 REG1A RELN SELL SELP SERPINE2 SERPINF1 SIRT1 SIRT3 SLC18A3 SLC2A1 SLC2A3 SLC8A1 SLC8A2 SLC8A3 SNAP91 SNCA SNCB SNCG SNRNP70 SNRPA SOD1 SOD2 SORL1 SOX13 SOX5 SOX6 SPINT1 STAT3 SYP TARDBP TBP TFAM THBD TLR4 TM2D1 TM2D2 TM2D3 TMED10 TNF TNFRSF1A TNFRSF1B TOMM40 TPH1 TSC2 TTR UQCRC1 VEGFA VIM VLDLR XRN1	10059 102 1020 1022 10452 10458 1051 10531 1080 10858 10891 10972 1103 1137 1139 1191 119391 1230 1234 1386 142 1432 148 1499 1509 1520 155 1588 1595 1627 1636 1743 1759 177 1778 18 1812 1813 1814 1815 1816 183 185 1869 1889 19 1917 1938 1950 1958 1965 2 2002 2023 2033 2043 2056 2057 2099 217 2186 2260 2309 23186 23236 23385 23410 23411 23435 23621 246 2515 25825 2597 26330 2641 2668 27344 2746 2752 2778 287 2896 2902 2903 2904 2932 3028 3030 3032 3039 3040 3077 308 3084 3091 3096 3097 3123 3156 3178 3181 322 324 3265 3284 3293 3297 3303 3304 3313 3315 3320 3329 333 334 335 3350 3356 337 3383 347 348 3480 3481 3485 3486 351 355 3551 3552 3558 3562 3565 3569 3570 3572 3574 3586 361 3630 3643 3658 3667 37 3708 3749 3778 3897 3949 3952 3990 4018 4023 4035 4043 4128 4133 4137 4153 4171 43 4311 4313 4318 4361 445 4493 4496 4502 4683 4684 4714 472 4722 4741 4747 4780 4803 4804 4842 4843 4846 4855 4908 4914 4915 4976 498 5037 5058 5074 5105 5110 5155 5176 51806 5270 5328 5333 5335 538 5444 5445 5446 54464 545 5465 5468 55553 5601 5610 5649 5653 56751 5705 572 5742 5743 581 5819 590 59269 5967 627 6352 6402 6403 6513 6515 6543 6546 6547 6572 6620 6622 6623 6625 6626 6647 6648 6653 6660 6692 6774 6855 6868 6908 7019 7056 7099 7124 7132 7133 7166 717 718 7249 7276 728 7384 7422 7431 7436 7804 80213 815 823 831 83877 839 83941 840 842 84687 8574 8639 8660 8754 8772 8829 9131 9370 9446 948 9575 9580 959 9749 9892 998	Homo sapiens (human)	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	5-HT1A 5-HT1B Ace Acer Ance Appl Atg6 Calx Dop1R1 Dop1R2 Dop2R E(bx) Eno Fas2 Gapdh1 Gapdh2 Glut1 Hmgcr InR N Nct Nep1 Nep3 Nep4 Nmdar1 Nrg Octbeta1R Octbeta2R Parp1 Pepck1 Psn Shaw Snmp2 Sod3 Spn27A Spn42Dd Spn88Ea Tace Tl VAChT amrt amx bisc htl nAChRalpha2 nAChRalpha6 nAChRbeta2 sgg vn	31002 31248 31293 31364 31547 31792 32342 32545 33005 33007 33351 3355109 33599 34189 34304 34805 35728 36232 37131 37191 37196 37443 38109 38657 38868 40260 40665 41549 41625 41726 42160 42449 42481 42549 42652 42795 42803 42850 42919 42920 42964 43222 43484 43558 43869 44811 45815 49804 49808	Drosophila melanogaster (fruit fly)	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	ENO1 ENO2 ERR1 ERR2 ERR3 GLR1 HMG1 HMG2 HRR25 HSF1 NFT1 PEP1 PEP4 STE20 TDH1 TDH2 TDH3 VPS1 VTH1 VTH2 VVS1 XRN1 YNR065C YPS3 YPS7	850812 851171 851950 852264 852543 852702 852806 853106 853169 853233 853395 853465 853870 853978 854575 854634 854900 855373 855802 855848 855897 855949 856014 856382 856579	Saccharomyces cerevisiae S288C	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	agtr1.L bace2.L bace2.S ctsd.S drd1.L drd2.L drd5.S eno1.S epha4.S epor.L fgfr1.L fgfr1.S gapdh.S gdnf.L grin1.L grin1.S grin2a.L hmgcr.L htr1a.L igf1r.S insr.L ldlr.L ldlr.S ntf3.L plcd1.L plcd1.S pon2.L pon2.S psen1.L psen2.S ttr.L	100127346 108699855 108705891 108710578 108718712 108719811 373644 378584 378605 380259 380298 380307 380341 397713 397750 397757 397782 397787 397953 398006 398022 398763 398806 399258 399298 399444 432039 443721 734211 779062 779087	Xenopus laevis (African clawed frog)	Alliance of Genome Resources
DOID:10652	Alzheimer's disease Aliases: Alzheimer disease Alzheimers dementia	ace bace2 fgfr1 notch1 pon2 tm2d2	100037842 100144634 100216145 448598 496785 548648	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:1067	open-angle glaucoma Aliases: Wide-angle glaucoma glaucoma simplex open angle glaucoma pigmentary glaucoma	pon2	448598	Xenopus tropicalis (tropical clawed frog)	Alliance of Genome Resources
DOID:1067	open-angle glaucoma Aliases: Wide-angle glaucoma glaucoma simplex open angle glaucoma pigmentary glaucoma	Octbeta2R	41549	Drosophila melanogaster (fruit fly)	Alliance of Genome Resources
DOID:1067	open-angle glaucoma Aliases: Wide-angle glaucoma glaucoma simplex open angle glaucoma pigmentary glaucoma	pon1	447803	Danio rerio (zebrafish)	Alliance of Genome Resources
DOID:1067	open-angle glaucoma Aliases: Wide-angle glaucoma glaucoma simplex open angle glaucoma pigmentary glaucoma	Adrb2 Apoc3 Il10 Il2 Myoc Pon1 Tnf	11555 11814 16153 16183 17926 18979 21926	Mus musculus (house mouse)	Alliance of Genome Resources
DOID:1067	open-angle glaucoma Aliases: Wide-angle glaucoma glaucoma simplex open angle glaucoma pigmentary glaucoma	cof-2 poml-1 poml-2	171999 183582 187297	Caenorhabditis elegans	Alliance of Genome Resources
DOID:1067	open-angle glaucoma Aliases: Wide-angle glaucoma glaucoma simplex open angle glaucoma pigmentary glaucoma	Il10 Il2 Myoc Pon1 Tnf	116562 24835 25325 81523 84024	Rattus norvegicus (Norway rat)	Alliance of Genome Resources
DOID:1067	open-angle glaucoma Aliases: Wide-angle glaucoma glaucoma simplex open angle glaucoma pigmentary glaucoma	ADRB2 APOC3 APOE GMDS IL10 IL2 MYOC OPTN PON1 TAP1 TNF	10133 154 2762 345 348 3558 3586 4653 5444 6890 7124	Homo sapiens (human)	Alliance of Genome Resources
DOID:1068	juvenile glaucoma Aliases: Glaucoma of childhood	MYOC	4653	Homo sapiens (human)	Alliance of Genome Resources
DOID:1068	juvenile glaucoma Aliases: Glaucoma of childhood	Myoc	17926	Mus musculus (house mouse)	Alliance of Genome Resources
DOID:1068	juvenile glaucoma Aliases: Glaucoma of childhood	Myoc	81523	Rattus norvegicus (Norway rat)	Alliance of Genome Resources
DOID:10685	separation anxiety disorder	Ngf	18049	Mus musculus (house mouse)	Alliance of Genome Resources
DOID:10685	separation anxiety disorder	ngfb	58133	Danio rerio (zebrafish)	Alliance of Genome Resources
DOID:10685	separation anxiety disorder	Ngf	310738	Rattus norvegicus (Norway rat)	Alliance of Genome Resources
DOID:10685	separation anxiety disorder	NGF	4803	Homo sapiens (human)	Alliance of Genome Resources
DOID:10690	mastitis Aliases: Inflammatory breast disease Inflammatory disease of breast breast inflammation	Tlr4 Tlr9	21898 81897	Mus musculus (house mouse)	Alliance of Genome Resources
DOID:10690	mastitis Aliases: Inflammatory breast disease Inflammatory disease of breast breast inflammation	Tl chp	43222 43690	Drosophila melanogaster (fruit fly)	Alliance of Genome Resources

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